1. Diagnosis And Treatment Of Peptic Ulcer Disease Information and discussion concerning causes, symptoms and treatment of peptic ulcers. http://www.diagnosishealth.com/ulcer.htm

DiagnosisHealth Health Discussions Disease Information Center PEPTIC ULCER DISEASE About the Author Dr. Minocha ( http://www.diagnosishealth.com/minocha.htm ) is the Professor of Medicine and Director, Division of Digestive Diseases at the University of Mississippi Medical Center in Jackson, MS, and is the author of How to Stop Heartburn; Simple Ways to Heal Heartburn and Acid Reflux What is peptic ulcer disease (PUD)? The term PUD generally refers to spectrum of disorders that includes gastric ulcer (GU), pyloric channel ulcer, duodenal ulcer (DU) and postoperative ulcers at or near the site of surgical anastomosis. HISTORICAL PERSPECTIVE Looking back at history, peptic ulcer was a rare and generally unrecognized as a cause of symptoms/complications or death until the early 19th century. Despite sporadic case reports beginning in late 18th century, Peptic Ulcer Disease did not become widely appreciated until early 20th century. The first 6 decades saw the dominance of surgery in the treatment of peptic ulcer. With the introduction of acid suppressive drugs like histamine-2 blockers in 1970s, the treatment of PUD was revolutionized. By nineteen eighties, the advent of Helicobacter pylori (HP) brought about a dramatic twist and possibly the cure. CAUSES OF PEPTIC ULCER DISEASE So what causes PUD? Numerous factors blamed in the pathogenesis of PUD. Many of these factors may be acquired during life, although some of these these may already be predetermined. Historically, stomach acid has been the most common factor blamed. No Acid No ulcer- is an old axiom which may be questionable in the nineties. As a group, patients with duodenal ulcer have high acid secretion. Increased acid secretion causes changes in the wall of duodenum (gastric metaplasia) setting the stage for invasion by HP.

2. EMedicine – Peptic Ulcer Disease (PUD, Peptic Ulcers Symptoms) : Article B Dr. George Fantry reports on symptoms and treatment of stomach and duodenal peptic ulcers often caused by Helicobacter pylori infections, NSAIDs, or stress. http://www.emedicine.com/med/topic1776.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Gastroenterology Peptic Ulcer Disease Last Updated: May 6, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: PUD Helicobacter pylori infection H pylori ... nonsteroidal anti-inflammatory drugs , NSAIDs, mucosal break, dyspepsia, heartburn, smoking stress , epigastric pain, belching, bloating, distention, fatty food intolerance, hematemesis , melena, gastrointestinal bleeding , Guaiac-positive stool, occult blood loss, succussion splash gastric outlet obstruction duodenal ulcers , perforation, gastrinoma Zollinger-Ellison syndrome multiple endocrine neoplasia syndrome MEN-I , antral G cell hyperplasia, systemic mastocytosis , basophilic leukemias, cirrhosis , chronic pulmonary disease, renal failure renal transplantation radiation-induced ulcers chemotherapy-induced ulcers , vascular insufficiency, crack cocaine duodenal obstruction AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: George T Fantry, MD

3. MedlinePlus: Peptic Ulcer From the National Institutes of Health; H. pylori and Peptic Ulcer (NationalDigestive Overviews; JAMA Patient Page peptic ulcers (American Medical http://www.nlm.nih.gov/medlineplus/pepticulcer.html

@import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Other health topics: A B C D ... List of All Topics Peptic Ulcer Contents of this page: From the NIH Overviews Diagnosis/Symptoms Treatment ... Teenagers Search MEDLINE/PubMed for recent research articles on Peptic Ulcer You may also be interested in these MedlinePlus related pages: Stomach Disorders Digestive System From the National Institutes of Health H. pylori and Peptic Ulcer (National Digestive Diseases Information Clearinghouse) Also available in: Spanish What I Need to Know about Peptic Ulcers (National Digestive Diseases Information Clearinghouse) Overviews JAMA Patient Page: Peptic Ulcers (American Medical Association) - Links to PDF Ulcers and H. pylori Infection (American Academy of Family Physicians) Diagnosis/Symptoms Breath Test for Helicobacter pylori (Cleveland Clinic Foundation) Helicobacter pylori Test (American Association for Clinical Chemistry) Upper Endoscopy (National Digestive Diseases Information Clearinghouse) Upper GI Series (National Digestive Diseases Information Clearinghouse) Treatment Ulcers: What You Can Do to Heal Your Ulcer (American Academy of Family Physicians) Also available in: Spanish Specific Conditions Gastritis (National Digestive Diseases Information Clearinghouse) Zollinger-Ellison Syndrome (National Digestive Diseases Information Clearinghouse) Related Issues Bleeding in the Digestive Tract (National Digestive Diseases Information Clearinghouse) Dangers of Aspirin and NSAIDS (American College of Gastroenterology)

4. Diagnosis And Treatment Of Peptic Ulcer Disease Information and discussion concerning causes, symptoms and treatment of peptic ulcers. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. MedlinePlus Medical Encyclopedia: Peptic Ulcer Most people with peptic ulcers have this organism living in their The abdominalpain from peptic ulcers can differ a lot from person to person. http://www.nlm.nih.gov/medlineplus/ency/article/000206.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Peptic ulcer Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... References Illustrations Ulcer emergencies Gastroscopy procedure Location of peptic ulcers Cause of peptic ulcers ... Stomach disease or trauma Alternative names Return to top Ulcer - peptic; Ulcer - duodenal or gastric; Duodenal ulcer Definition Return to top A peptic ulcer is erosion in the lining of the stomach or duodenum (the first part of the small intestine). The word “peptic” refers to pepsin, a stomach enzyme that breaks down proteins.  If a peptic ulcer is located in the stomach it is called a gastric ulcer. A peptic ulcer in the stomach is called a gastric ulcer Small ulcers may not cause any symptoms. Large ulcers can cause serious bleeding. Most ulcers occur in the first layer of the inner lining. A hole that goes all the way through is called a perforation of the intestinal lining. A perforation is a medical emergency. Causes, incidence, and risk factors

6. Wine Spectator Wine, Beer Wipe Out Ulcer-Causing Bacteria Research shows that moderate consumption of wine or beer helps rid the body of bacteria which is suspected of causing peptic ulcers. http://www.winespectator.com/Wine/Daily/News/0,1145,1945,00.html

var section = "9"; Access to ratings and tastings notes for more than 148,000 wines Web exclusive columns and articles Advance rating notification from upcoming Wine Spectator issues FREE online newsletter with Editors' Picks Plus: Wine Picks of the Day, Restaurant and Travel Recommendations, Food and Wine Matching Tips, and much more

7. Medinfo Peptic Ulcer These are known as stomach and duodenal ulcers, collectively known as peptic ulcers. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Peptic Ulcers - Health Information peptic ulcers. Ulcers are small, open craters or sores that develop in the lining of the stomach or the duodenum, the first section of the small http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. MedlinePlus Peptic Ulcer What I Need to Know about peptic ulcers (National Digestive Diseases Information Clearinghouse) Overviews http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. Helicobacter Pylori And Peptic Ulcer Disease More results from www.cdc.gov peptic ulcersMany people think that spicy foods cause ulcers, but the truth is that a type ofbacterium is the main culprit. Read this article to learn more about peptic http://www.cdc.gov/ulcer

Division of Bacterial and Mycotic Diseases Helicobacter pylori and Peptic Ulcer Disease Menu Good News - A Cure for Ulcers! H. pylori Fact Sheet for Health Care Providers Economic Impact of Ulcers ... Education Materials Order Form Related Contents Foodborne and Diarrheal Diseases Branch DBMD Disease Listing - H. pylori CDC Morbidity and Mortality Weekly Report (MMWR) A peptic ulcer is a sore or hole in the lining of the stomach or duodenum (the first part of the small intestine). People of any age can get an ulcer and women are affected just as often as men. Over 25 million Americans will suffer from an ulcer at some point during their lifetime. The good news is that most ulcers are caused by an infection with the bacterium, Helicobacter pylori , and can be cured in about two weeks with antibiotics. Ulcer Facts Most ulcers are caused by an infection, not spicy food, acid or stress.

11. MedlinePlus Medical Encyclopedia Peptic Ulcer Illustrations. Ulcer emergencies. Gastroscopy procedure. Location of peptic ulcers. Cause of peptic ulcers. Stomach disease or trauma http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. The Helicobacter Foundation Dedicated to providing latest information about Helicobacter pylori, its diagnosis, treatment and clinical correlations. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. EMedicine Health Peptic Ulcers Information, articles and statistics of peptic ulcers, causes of peptic ulcers and peptic ulcer treatment. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. Helicobacter Pylori And Peptic Ulcer many ulcers are asymptomatic and the accurate diagnosis of duodenal ulcers by radiographic methods is difficult. Mortality from peptic ulcers http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. What You Really Need To Know About Ulcers Gastric And Duodenal What You Really Need to Know About Ulcers Gastric and Duodenal peptic ulcers Cast, Crew, Reviews, Plot Summary, Comments, Discussion, Taglines http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Helicobacter Pylori And Peptic Ulcer Disease Diseases Helicobacter pylori and Peptic Ulcer Disease See the menu in Espa ol/Spanish Menu. . Good News A Cure for Ulcers! http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. H. Pylori And Peptic Ulcer Discusses peptic ulcers and explains how H. pylori can cause them. Also providesinformation on diagnosis and treatment. http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/

Email To A Friend Spanish Version Also see: What I need to know about Peptic Ulcers Home Digestive Diseases A-Z List of Topics and Titles H. pylori and Peptic Ulcer H. pylori and Peptic Ulcer On this page: What is a peptic ulcer? What is H. pylori How does ... Points to Remember What is a peptic ulcer? A peptic ulcer is a sore on the lining of the stomach or duodenum, which is the beginning of the small intestine. Peptic ulcers are common: One in 10 Americans develops an ulcer at some time in his or her life. One cause of peptic ulcer is bacterial infection, but some ulcers are caused by long-term use of nonsteroidal anti-inflammatory agents (NSAIDs), like aspirin and ibuprofen. In a few cases, cancerous tumors in the stomach or pancreas can cause ulcers. Peptic ulcers are not caused by stress or eating spicy food, but these can make ulcers worse. Top What is H. pylori? Helicobacter pylori H. pylori ) is a type of bacteria. Researchers believe that H. pylori is responsible for the majority of peptic ulcers. H. pylori

18. NSAIDs And Peptic Ulcers But some peptic ulcers are caused by prolonged use of nonsteroidal Anyone takingNSAIDs who experiences symptoms of peptic ulcer should see a doctor for http://digestive.niddk.nih.gov/ddiseases/pubs/nsaids/

Email To A Friend Also see: What I need to know about Peptic Ulcers Home Digestive Diseases A-Z List of Topics and Titles : NSAIDs and Peptic Ulcers NSAIDs and Peptic Ulcers A peptic ulcer is a sore that forms in the lining of the stomach or the duodenum (the beginning of the small intestine). An ulcer can cause a gnawing, burning pain in the upper abdomen; nausea; vomiting; loss of appetite; weight loss; and fatigue. Most peptic ulcers are caused by infection with the bacterium Helicobacter pylori (H. pylori). But some peptic ulcers are caused by prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxen sodium. Normally the stomach has three defenses against digestive juices: mucus that coats the stomach lining and shields it from stomach acid, the chemical bicarbonate that neutralizes stomach acid, and blood circulation to the stomach lining that aids in cell renewal and repair. NSAIDs hinder all of these protective mechanisms, and with the stomach's defenses down, digestive juices can damage the sensitive stomach lining and cause ulcers. NSAID-induced ulcers usually heal once the person stops taking the medication. To help the healing process and relieve symptoms in the meantime, the doctor may recommend taking antacids to neutralize the acid and drugs called H2-blockers or proton-pump inhibitors to decrease the amount of acid the stomach produces.

19. Stomach And Duodenal Ulcers (Peptic Ulcers) - Digestive Disorders Factors in the development of peptic ulcers These ulcers are referred to aspeptic ulcers gastric ulcers in the stomach and duodenal ulcers in the http://www.umm.edu/digest/ulcers.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Digestive Disorders Common Digestive Disorders... Inflammatory Bowel Diseases... Irritable Bowel Syndrome ... Site Index Related Resources Within UMM Gastroenterology Translate using Google to Spanish German French Italian Portuguese Digestive Disorders Stomach and Duodenal Ulcers (Peptic Ulcers) What is a stomach or duodenal ulcer? An ulcer is an open sore, or lesion, usually found on the skin or mucous membrane areas of the body. An ulcer in the lining of the stomach or duodenum, where hydrochloric acid and pepsin are present, is referred to as a peptic ulcer When the ulcer is in the stomach, it is called a gastric ulcer When the ulcer is in the duodenum, it is called a duodenal ulcer What causes gastric and duodenal ulcers? In the past it was believed lifestyle factors, such as stress and diet caused ulcers. Later, researchers determined that stomach acids hydrochloric acid and pepsin contributed to ulcer formation. Today, research shows that most ulcers (80 percent of gastric ulcers and 90 percent of duodenal ulcers) develop as a result of infection with a bacterium called Helicobacter pylori (H. pylori).

20. Peptic Ulcers - UMMC An indepth report on the causes, diagnosis, treatment, and prevention of stomachand GI ulcers. http://www.umm.edu/patiented/articles/what_symptoms_of_peptic_ulcers_000019_3.ht

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Home Medical Reference Patient Education WHAT ARE THE SYMPTOMS OF PEPTIC ULCERS? Dyspepsia and Common Symptoms of Ulcers The most common symptoms of peptic ulcers are known collectively as dyspepsia . Peptic ulcers can occur without dyspepsia or any gastrointestinal symptoms, especially when caused by NSAIDs. Dyspepsia may be persistent or recurrent and can encompass a variety of problems in the upper abdomen, including the following: Pain or discomfort. [See Ulcer Pain , below, for more detailed description.] Bloating. A feeling of fullness. (People with severe dyspepsia are unable to drink as much water or other beverages as people with mild or no dyspepsia.) Hunger and an empty feeling in the stomach, often one to three hours after a meal. Mild nausea. (Vomiting, in fact, may relieve symptoms.) Regurgitation. (The sensation of acid backing up into the throat.) Belching. Ulcer Pain. The pain of ulcers can be either localized in one place or diffuse. The pain has been described as burning, gnawing, or aching in the upper abdomen, or as a stabbing pain penetrating through the width of the gut. The symptoms may vary depending on the location of the ulcer: Duodenal ulcers often cause a gnawing pain in the upper stomach area several hours after a meal, and the pain is often relieved by eating a meal.

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