1. MedlinePlus Medical Encyclopedia: Pellagra Adam.com looks at this disorder, its alternate names and symptoms. http://www.nlm.nih.gov/medlineplus/ency/article/000342.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Pellagra Contents of this page: Illustrations Alternative names Definition Illustrations Food guide pyramid Alternative names Return to top Vitamin deficiency - niacin; Deficiency - niacin Definition Return to top Pellagra is a disease that occurs when a person does not get enough niacin (one of the B complex vitamins) or tryptophan (an amino acid) in their diet. It can also occur if the body fails to absorb these nutrients. The disease is common in certain parts of the world (in people consuming large quantities of corn). It is characterized by scaly skin sores, diarrhea, inflamed mucous membranes, and mental confusion and delusions. It may develop after gastrointestinal diseases or alcoholism. Update Date: 10/23/2004 Updated by: Kevin Pho, M.D., Attending, Internal Medicine, Boston VA Medical Center, Boston, MA. Review provided by VeriMed Healthcare Network. Home Health Topics Drug Information Encyclopedia ... U.S. National Library of Medicine , 8600 Rockville Pike, Bethesda, MD 20894 National Institutes of Health Page last updated: 18 August 2005

2. Exhibits And Galleries Informative article on the history of this disorder. http://www.nih.gov/od/museum/exhibits/goldberger/main.html

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3. NIACIN Pellagra Dementia pellagra, the classic niacin deficiency disease is characterized by bilateral dermatitis in sun exposed areas, glossitis, diarrhea, and dementia. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Pellagra NIACIN pellagra dementiapellagra, the classic niacin deficiency disease,is characterized by bilateraldermatitis in sun exposed areas, glossitis, diarrhea, and dementia. http://www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Pellagra

5. NIACIN Pellagra Dementia A discussion on niacin and how its absorbed, deficiencies, diet recommendations, food sources and toxicity. http://www.eagle-min.com/faq/faq100.htm

Toll Free 1 888 441 4184 SupraLife Online Shopping cart Shopping Cart Full Spectrum Specialized ... Sports Our Family Bio-lumin Supralife Youngevity Niacin Niacin (nicotinic acid or nicotinamide) is essential in the form of the coenzymes nicotinamide adenine dinucleotide (NAD) and NAD phosphate (NADP) in which the nicotinamide moiety acts as an electron acceptor or hydrogen donor in many biological redox reactions. NAD functions as an electron carrier for intracellular respiration, as well as a codehydrogenase with enzymes involved in the oxidation of fuel molecules. NADP functions as a hydrogen donor in reductive biosyntheses such as in fatty acid and steroid syntheses and, like NAD, as a codehydrogenase. Nicotinic acid and nicotinamide are rapidly absorbed from the stomach or the intestine. Nicotinamide, the major form in the bloodstream, arises from enzymatic hydrolysis of NADP in the intestinal mucosa and liver. It is transported to tissues that synthesize their own NAD as needed. Niacin and NAD are biosynthesized from dietary tryptophan via the kynurenine pathway and quinolinic acid. Excess niacin is excreted in the urine primarily as N -methylnicotinamide and N -methyl-2-pyridone-5-carboxamide.

6. Symptoms Of Pellagra - WrongDiagnosis.com Symptoms of pellagra including signs, symptoms, incubation period, duration, and correct diagnosis. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. A Science Odyssey: People And Discoveries: Pellagra Shown To Be Dietary Disease In 1914, the surgeon general appointed him to tackle the crisis of pellagra.pellagra had been a lowlevel problem throughout the South for years, http://www.pbs.org/wgbh/aso/databank/entries/dm15pa.html

Pellagra shown to be dietary disease Photo: Man with Pellagra on arms By 1912, Joseph Goldberger had been a member of the U.S. Public Health Service for 13 years. In 1914, the surgeon general appointed him to tackle the crisis of pellagra. Pellagra had been a low-level problem throughout the South for years, but crop failures and an economic downturn had raised it to epidemic proportions. The disease causes skin rashes, mouth sores, diarrhea, and if untreated, mental deterioration. Goldberger's first step was to simply observe. He traveled tirelessly through the South, taking notes, asking questions, and watching. He noticed that the diet of poor people in the region consisted of cornbread, molasses, and a little pork fat. It seemed that the poorer people were, the more likely they were to get pellagra. Institutions such as prisons, asylums, and orphanages also had a limited diet and a great deal of pellagra among inmates. Goldberger gradually concluded that the disease was not infectious at all, but strictly a matter of diet. In 1915, he conducted experiments on inmates at a Mississippi prison, who volunteered for the study in exchange for a pardon. Because it was a farm prison, its inmates had a fairly balanced diet. Goldberger's volunteers were given the poor Southern diet he had seen associated with pellagra. That was the only difference. The other inmates ate the usual farm fare. Every effort was made to prevent and rule out infectious transmission. And within months, the volunteers came down with pellagra. Then the researchers

8. Exhibits And Galleries An essay on a pioneer in Public Health. Authored by Alan Kraut, Ph.D., Professor of History, American University. http://www.nih.gov/od/museum/exhibits/goldberger/full-text.html

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9. MedlinePlus Medical Encyclopedia Pellagra pellagra Contents of this page Illustrations. Alternative names. Definition http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. EMedicine - Pellagra : Article By Kumaravel Rajakumar, MD pellagra pellagra defines the systemic disease resulting from niacin deficiency.Don Gasper Casal, a Spanish court physician, first described pellagra. http://www.emedicine.com/ped/topic1755.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Nutrition Pellagra Last Updated: June 25, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: niacin deficiency, Alpine scurvy, maidism, mal de la rosa, mal rosso, mayidism, psychoneurosis maidica, Saint Ignatius itch, Saint Ignatius' itch, maize, corn AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Kumaravel Rajakumar, MD , Assistant Professor, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Kumaravel Rajakumar, MD, is a member of the following medical societies: Ambulatory Pediatric Association , and American Academy of Pediatrics Editor(s): Steven Schwarz, MD , Chairman, Department of Pediatrics, Long Island College Hospital; Professor of Pediatrics, State University of New York Downstate Medical Center; Robert Konop, PharmD

11. Pellagra Principal Health News pellagra is a disorder brought on by a deficiency of the nutrient called niacin or nicotinic acid, one of the Bcomplex vitamins. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. EMedicine - Pellagra : Article By Vladimir Hegyi, MD pellagra pellagra is clinically manifested by the 4 D s photosensitivedermatitis, diarrhea, dementia, and death. The full tetrad of symptoms is usually http://www.emedicine.com/derm/topic621.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Dermatology Internal Medicine Pellagra Last Updated: August 10, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: avitaminosis, niacin deficiency, vitamin deficiency, vitamin B-3 deficiency AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Vladimir Hegyi, MD , Associate Professor, Department of Pediatric Dermatovenereology, Pediatric Hospital, Comenius University, Bratislava Coauthor(s): Robert A Schwartz, MD, MPH , Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School Vladimir Hegyi, MD, is a member of the following medical societies: European Academy of Dermatology and Venereology , European Dermatology Forum, German Society for Dermatology Slovak Dermatovenereological Society , Slovak Medical Association, and Union European Medical Specialists Editor(s): James Fulton, Jr, MD, PhD

13. A Science Odyssey People And Discoveries Pellagra Shown To Be pellagra shown to be dietary disease 1915 pellagra shown to be dietary disease 1915. Photo Man with pellagra on arms http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. Pellagra - Wikipedia, The Free Encyclopedia pellagra is a vitamin deficiency disease caused by dietary lack of niacin pellagra became common only when corn became a staple that was eaten without http://en.wikipedia.org/wiki/Pellagra

You did it! Over US$240,000 was donated in the 21 day fund drive. Thank you for your generosity! You are still welcome to make a donation or purchase Wikimedia merchandise Pellagra From Wikipedia, the free encyclopedia. Pellagra is a vitamin deficiency disease caused by dietary lack of niacin and protein . A dietary deficiency in the essential amino acid tryptophan and niacin can result in a deficiency in niacin (which is a B vitamin ) and can result in pellagra. Symptoms of pellagra are red skin lesions, diarrhea dermatitis , weakness, mental confusion, and eventually dementia . This disease can be common for persons who obtain most of their food energy from corn , as corn is a poor source of lysine, and any lysine it contains is chemically bound. Therefore this disease can be common amongst people who live in rural South America where — during winter — they live off corn. Usually the symptoms show during spring, and disappear over summer, to return the next spring, after another long winter. It is also one of several diseases of malnutrition common in Africa , and was endemic in northern Italy.

15. Pellagra See D. A. Roe, A Plague of Corn A Social History of pellagra (1973). pellagra breaks out in faminehit Zambia. (Xinhua News Agency) http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Introduction: Pellagra - WrongDiagnosis.com Introduction to pellagra as a medical condition including symptoms, diagnosis,misdiagnosis, treatment, prevention, and prognosis. http://www.wrongdiagnosis.com/p/pellagra/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Pellagra Next sections Basic Summary for Pellagra Causes of Pellagra Symptoms of Pellagra Misdiagnosis of Underlying Causes of Pellagra ... Statistics about Pellagra Next chapters: Biotin deficiency Vitamin E deficiency Vitamin E overdose Vitamin D overdose ... Feedback Introduction: Pellagra Pellagra: Dietary deficiency of vitamin B3 (niacin) Researching symptoms of Pellagra: Further information about the symptoms of Pellagra is available including a list of symptoms of Pellagra , or alternatively return to research other symptoms in the symptom center Causes of Pellagra: Research more detailed information about the causes of Pellagra , other possibly hidden causes of Pellagra , or other general information about Pellagra Statistics and Pellagra: Various sources and calculations are available in statistics about Pellagra , and you can also research other medical statistics in our statistics center Contents for Pellagra: Basic Summary for Pellagra Causes of Pellagra Symptoms of Pellagra Misdiagnosis of Underlying Causes of Pellagra ... Diseases Did we miss something? Please provide

17. Dr. Joseph Goldberger And The War On Pellagra, By Alan Kraut, Ph.D. Next Page (1 of 8) Dr. Joseph Goldberger the War on pellagra Home Goldberger and the "pellagra Germ" Goldberger vs. The South http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. Symptoms Of Pellagra - WrongDiagnosis.com Symptoms of pellagra including signs, symptoms, incubation period, duration, andcorrect diagnosis. http://www.wrongdiagnosis.com/p/pellagra/symptoms.htm

Home Symptoms Diseases Risks ... Pellagra Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Pellagra Next sections Misdiagnosis of Underlying Causes of Pellagra Statistics about Pellagra Hospital Statistics for Pellagra Glossary for Pellagra Next chapters: Biotin deficiency Vitamin E deficiency Vitamin E overdose Vitamin D overdose ... Feedback Symptoms of Pellagra General information about symptoms of Pellagra: The symptom information on this page attempts to provide a list of some possible symptoms of Pellagra. This symptom information has been gathered from various sources, may not be fully accurate, and may not be the full list of symptoms of Pellagra. Furthermore, symptoms of Pellagra may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of symptoms and whether they are indeed symptoms of Pellagra. List of symptoms of Pellagra: The list of symptoms mentioned in various sources for Pellagra includes: Weakness Skin inflammation Diarrhea Weight loss ... Memory loss More symptoms of Pellagra: In addition to the above information, to get a full picture of the possible symptoms of this condition and its related conditions, it may be necessary to examine symptoms that may be caused by complications of Pellagra

19. Niacin And Pellagra - Part 2 Innovative hypotheses about Lyme disease, pellagra, and niacin, part 2. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

20. Pellagra pellagra. pellagra. Goldberger, Joseph and GA Wheeler. The Experimental Productionof pellagra in Human Subjects by Means of Diet. http://www.mc.vanderbilt.edu/biolib/hc/nh7.html

Previous Title Title List Next Title Pellagra Pellagra Goldberger, Joseph and G.A. Wheeler. The Experimental Production of Pellagra in Human Subjects by Means of Diet . Washington: Government Printing Office, 1920. (Hygienic Laboratory Bulletin) Previous Title Title List Next Title VUMC ... Mary.Teloh@vanderbilt.edu Last modified: Tuesday, 09 August 2005

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