101. The Parkinson's Institute - An independent notfor-profit institution dedicated to seeking the cause andfinding a cure for Parkinson s disease, while providing the best possible care http://www.parkinsonsinstitute.org/

Home Care Cause Cure Home Care Cause Cure ... Admin

102. Health Matters - Library A-Z Parkinson s disease is a degenerative neurological condition. The main symptomsare abnormalities of movement, such as tremor and muscular rigidity. http://www.abc.net.au/health/library/ff_parkinsons.htm

ABC Home Radio Television News ... More info Parkinson's fact file Parkinson's disease is a degenerative neurological condition. The main symptoms are abnormalities of movement, such as tremor and muscular rigidity. by Peter Lavelle Background Parkinson's disease was named after Scottish physician James Parkinson, who published a description of the condition, An Essay on the Shaking Palsy , in 1817. This joined an already substantial collection of his works, including Observations on the excessive indulgence of children (1807) and Observations on the act for regulating mad-houses Today he's best known for the former. Parkinson's disease is a degenerative neurological condition. Over the last decade, it's been given an especially high profile by celebrities who've been affected by it, like Michael J. Fox, Katherine Hepburn, Muhammad Ali, and Pope John Paul. More than 30,000 people in Australia have Parkinson's disease, which makes it the second most common degenerative neurological condition after Alzheimer's disease. It affects men and women equally and it's more common in people over 50, though it can occur in younger people: about one in 10 of those diagnosed are under 40. top Symptoms Deep inside the brain are specialised areas responsible for coordinating body movements, called the basal ganglia. They connect with other areas of the brain via a neurotransmitter (messenger chemical) called dopamine, helping to make the body's muscular movements smooth and regular.

103. EMedicine - Parkinson Disease : Article By Jeff Blackmer, MD Parkinson disease James Parkinson first described Parkinson disease (PD) in 1817.PD is one of a number of chronic progressive central nervous system http://www.emedicine.com/pmr/topic99.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Physical Medicine and Rehabilitation Movement Disorders Parkinson Disease Last Updated: August 31, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: Parkinsonism, idiopathic Parkinson disease, PD, Parkinson's disease AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Jeff Blackmer, MD , Medical Director, Neurospinal Service, Assistant Professor, Division of Physical Medicine and Rehabilitation, The Rehabilitation Centre Jeff Blackmer, MD, is a member of the following medical societies: American Paraplegia Society Canadian Association of Physical Medicine and Rehabilitation Canadian Medical Association , and Royal College of Physicians and Surgeons of Canada Editor(s): Milton J Klein, DO , Consulting Staff, Department of Physical Medicine and Rehabilitation, Sewickley Valley Hospital and Ohio Valley General Hospital; Francisco Talavera, PharmD, PhD

104. Clinical Aspects Of Parkinson's Disease Although some symptoms of Parkinson s disease are found in many of these other The nature and severity of symptoms in Parkinson s disease vary from one http://www.mayo.edu/fpd/pd-info/clinical.htm

Parkinson's Most Common Symptoms In order to avoid confusion, it is important to remember that Parkinson's disease (or PD) is merely the most common in a group of conditions collectively refered to as 'parkinson ism '. Although some symptoms of Parkinson's disease are found in many of these other conditions, (see 'Parkinson's plus'- below) they also have additional features which distinguish them, different causes and different disease progressions. Unless otherwise stated, this site refers to Parkinson's Disease. The nature and severity of symptoms in Parkinson's disease vary from one person to another. In the beginning, symptoms may be very subtle. Eventually you may experience: Tremor of a hand when it's in a relaxed position (resting tremor). It may increase during stressful times and it's often worse on one side of the body. Rigidity or stiffness in the muscles. Slowness of movement (called bradykinesia) and a delay in initiating movements, Poor balance. Usually occurs when making a sudden change in the body's position. Walking problems. These include short, shuffling steps, and an inability to take the next step (gait "freezing").

105. Parkinson S Disease With Additional Symptoms Patients eventually develop symptoms of both Parkinson s disease (eg slowedmovement, ridity) and autonomic (linked to parts of the body not under concious http://www.mayo.edu/fpd/pd-info/parkplus.htm

Parkinson's Disease with Additional Symptoms 'Parkinson's Plus' is a name given to a group of disorders with parkinsonian symptoms, but with additional features. While the clinical symptoms of these disorders overlap with Parkinson's disease, the underlying neuropathology is often different and individuals may require alternate treatments. We've tried to provide an informative passage on each of these disorders, but for further information, please see our links for other sources. Dementia with Lewy Bodies Cortical Lewy bodies of dementia with Lewy bodies (DLB) are noticeably smaller and different in appearance, both with a standard H+E stain, and with an anti-synuclein staining (see figure). Prior to the identification of Lewy bodies in demented patients, the 50% (approx.) of dementia cases not attributable to pure Alzheimer's disease were assumed the result of vascular dementia. The discovery of Lewy bodies in the brains of demented patients by Kosaka and coleagues (1984) prompted a variety of new diagnoses i.e. dementia with Lewy bodies, diffuse Lewy body disease, Lewy body variant of Alzheimer's disease and others. More recently, the umbrella term 'Dementia with Lewy bodies' has been used - distinctions between different Lewy dementias were probably due to the variable bias between research groups. As a result, today's DLB is probably the second most common form of dementia after Alzheimer's disease. In DLB, patients usually initially develop Alzheimer's like dementia symptoms or parkinsonian signs and subsequently progress to symptoms of the other condition. McKeith and colleagues (1996) defined the features of possible or probable DLB diagnoses. These are (2 needed for a probable, 1 for a possible diagnosis):

106. American Parkinson Disease Association - Washington State Chapter The Washington State Chapter of the American Parkinson disease Association ishere to help people who deal with Parkinson s disease, whether patients, http://www.waparkinsons.org/

ABOUT APDA SUPPORT GROUPS GET INVOLVED DOWNLOAD THE YOPD SURVEY The Washington State Chapter of the APDA is here to help patients, family members, and caregivers cope with Parkinson's disease. Our role is to inform. assist, educate and raise funds to help ease the burden and find the cure. And, most of all, to care. Donate Newsletters News and Events: It's Here! Straight Talk About Parkinson's Disease Find out more! Interests, Issues and Concerns Forums The Washington Coalition of Citizens with disAbilities (WCCD) and the New Wings Advisory Council invite people with disabilities and their families living in King County to participate in one of a series of forums. Participants are asked to share their interests, issues and concerns related to living with disabilities in our area. APDA's Information and Referral Center joins other area organizations in co-sponsoring this muti-site event. Find out more! Hold this date!!! On Saturday, October 8th, APDA of Washington State will be holding the 21st Annual Parkinson's Symposium Location: Shoreline Conference Center Shoreline, WA

107. Parkinson's Disease Tutorial Parkinson s disease. Basal Ganglia Animation Simulating the System UnderlyingParkinson s disease (To view this animation, you ll need to download the http://www.sci.sdsu.edu/multimedia/basalgang/

SDSU Home Sciences Home Sciences Site Map Feedback Parkinson's Disease Basal Ganglia Animation Simulating the System Underlying Parkinson's Disease (To view this animation, you'll need to download the Shockwave plugin) Description of this animation What is the importance of this animation? developed for The Freshman Neuroscience Course, Winter 1995 Loma Linda University School of Medicine Course Coordinator: Michael Kirby, Ph.D. For the "Introduction to Motor Systems" lecture of A. Douglas Will, M.D.. Dr. Doug Will was the inspiration behind this animation, and it serves as a great help to medical students. This Shocked animation was created in collaboration with Jeff Sale . If you are interested in obtaining more information about this animation, please send email to jsale@sunstroke.sdsu.edu

108. BrainTalk Communities - Parkinson's Disease Threads in Forum Parkinson s disease, Forum Tools, Search this Forum Parkinson s disease linked to personality. juanhch. Yesterday 0740 PM http://brain.hastypastry.net/forums/forumdisplay.php?f=199

109. Parkinson S Disease Treatment - STALEVO (carbidopa/levodopa Learn about Stalevo, a treatment for Parkinson s disease, and find informationfor patients and caregivers about Parkinson s disease. http://www.stalevo.com/index.jsp

110. Welcome To NHS Direct Online Parkinson’s disease is a progressive, neurological condition which affects about120000 However, younger people can also have Parkinson’s disease, http://www.nhsdirect.nhs.uk/en.asp?TopicID=349

111. Introduction: Parkinson's Disease - WrongDiagnosis.com Introduction to Parkinson s disease as a medical condition including symptoms,diagnosis, misdiagnosis, treatment, prevention, and prognosis. http://www.wrongdiagnosis.com/p/parkinsons_disease/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Parkinson's Disease Next sections Basic Summary for Parkinson's Disease Prevalence and Incidence of Parkinson's Disease Prognosis of Parkinson's Disease Types of Parkinson's Disease ... Causes of Parkinson's Disease Next chapters: Meningitis Bacterial meningitis Pneumococcal meningitis Fungal meningitis ... Feedback Introduction: Parkinson's Disease Parkinson's Disease: A degenerative brain disorder that typically appears after 50 but can occur in younger adults. The charactistic symptom of Parkinson's is uncontrollable shaking called tremor , usually starting in the hands. Gradual progression of Parkinson's disease causes symptoms throughout the body. In many cases the cause is unclear, but Secondary Parkinson's disease can occur can be caused by various underlying causes such as brain injury or certain brain infections. Parkinson's Disease: Parkinson's disease belongs to a group of conditions called motor system disorders. Parkinson's and related disorders are the result of the loss of dopamine-producing brain cells.

112. Science, Medicine, And The Future: Parkinson's Disease -- Schapira 318 (7179): 3 Parkinson s disease is the commonest neurodegenerative disease after The mainchallenges in the treatment of Parkinson s disease are therefore (a) to http://bmj.bmjjournals.com/cgi/content/full/318/7179/311

Home Help Search Archive ... Table of Contents Author Keyword(s) Vol Page [Advanced] This article Extract PDF Respond to this article Read responses to this article ... View citation map Services Email this article to a friend Find similar articles in BMJ Find similar articles in PubMed Alert me to new issues of the journal ... Read articles citing this article PubMed PubMed Citation Articles by Schapira, A H V Related content Other Neurology BMJ 1999;318:311-314 ( 30 January ) Clinical review Science, medicine, and the future Parkinson's disease A H V Schapira professor of clinical neurosciences University Department of Clinical Neurosciences, Royal Free and University College Medical School and Institute of Neurology, University College London, London Parkinson's disease is the commonest neurodegenerative disease after Alzheimer's disease, with an estimated incidence of 20/100 000 and a prevalence of 150/100 000. It is characterised clinically by asymmetric onset of bradykinesia, rigidity, and, usually, resting tremor. The cause of the most common clinical features is the

113. Parkinson's Disease - Health And Medical Information Produced By Doctors - Medic Doctorproduced health and medical information written for you to make informeddecisions about your health concerns. http://www.medicinenet.com/parkinsons_disease/article.htm

document.writeln(''); MedicineNet Home > Parkinson's Disease search help Printer-Friendly Format FREE Newsletters Email to a Friend ... Next Parkinson's Disease Introduction What is Parkinson's disease? What causes Parkinson's disease? Who gets Parkinson's disease? ... What research is being done for Parkinson's disease? Introduction Parkinson's disease may be one of the most baffling and complex of the neurological disorders. Its cause remains a mystery but research in this area is active, with new and intriguing findings constantly being reported. Parkinson's disease was first described in 1817 by James Parkinson, a British physician who published a paper on what he called "the shaking palsy." In this paper, he set forth the major symptoms of the disease that would later bear his name. For the next century and a half, scientists pursued the causes and treatment of the disease. They defined its range of symptoms, distribution among the population, and prospects for cure. In the early 1960s, researchers identified a fundamental brain defect that is a hallmark of the disease: the loss of brain cells that produce a chemical - dopamine - that helps direct muscle activity. This discovery pointed to the first successful treatment for Parkinson's disease and suggested ways of devising new and even more effective therapies.

114. Parkinson S Disease - Novartis Pharmaceutical Learn about Parkinson s disease, including symptoms, causes, diagnosis, treatmentoptions, and more. http://www.pharma.us.novartis.com/conditions/az/parkinsons_disease.jsp

115. BBC - Health - Conditions - Parkinson's Disease A guide to Parkinson s disease. In Parkinson s disease degeneration of thesenerve cells means not enough dopamine is made and messages transmitted from http://www.bbc.co.uk/health/conditions/parkinsons1.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index FRIDAY 9th September 2005 Text only BBC Homepage Lifestyle Health ... Help Like this page? Send it to a friend! Parkinson's disease Dr Rob Hicks Parkinson's is a degenerative disease of the brain that affects the nerve cells involved in movement. In this article What is it? What are the symptoms? How is it treated? Further help What is it? Normally nerve cells in the part of the brain called the basal ganglia produce dopamine, a chemical messenger used to transmit nerve impulses from the brain to various parts of the body. In Parkinson's disease degeneration of these nerve cells means not enough dopamine is made and messages transmitted from the brain to the muscles become less efficient. What are the symptoms? Hand tremor is often the earliest sign. Other symptoms include slowness of movement, muscle rigidity, poor coordination and clumsiness. As the disease progresses movement and everyday tasks such as dressing and writing become more difficult. Speech may also be affected. A person with Parkinson's may develop an expressionless or 'mask-like' face. Many people experience depression and some develop dementia. After several years sufferers may develop a shuffling walk without arm movement. Initiating activity may be difficult but once started they move too fast and end up almost running.

116. PLWP - People Living With Parkinson's Providing information to the Parkinson s Community; encourages mutual supportand friendship for people living with this disease, their partners, family, http://www.plwp.org/

//Top Nav Bar I v2- By Constantin Kuznetsov Jr. (script@esolutiononline.com) //Modified by Dynamic Drive for NS6/Opera6 compatibility and code streamlining March 4th, 2002 //Visit http://www.dynamicdrive.com for this script var keepstatic=0 //specify whether menu should stay static 0=non static (works only in IE4+) var menucolor="#000000" //specify menu color var submenuwidth=150 //specify sub menus' color Our thoughts and prayers are with the victims of Katrina. The heart of PLWP is it’s people. The beating of the heart is shared in the PLWP Chat Room Share our dream...share our vision! Our primary focus is YOU...your quality of life! Whether you have been diagnosed with Parkinson's Disease, are "SHARE PARTNER" to a person diagnosed with it or have an interest in Parkinson's Disease, we hope you find a home here. WELCOME CHATROOM J oin ... Medallion Sponsors Text in RED is hyperlinked Menu Welcome Comm Center Donation FAQs Guestbook Join PLWP Directors Co-founders Medallion Journals Links Library MAD Library Member Webs Photo Gallery Poetry Forum PLWP Archives E-Card Shop Event Sponsors Game Arcade Parkie Porch Team Pages Volunteer Hi, my name is

117. Parkinson's Disease: Definition And Much More From Answers.com Par·kin·son s disease ( pär kins?nz ) n. A progressive nervous disease occuringmost often after the age of 50, associated with the destruction of. http://www.answers.com/topic/parkinson-s-disease

showHide_TellMeAbout2('false'); Business Entertainment Games Health ... More... On this page: Dictionary Encyclopedia Health Medical WordNet Wikipedia Best of Web Mentioned In Or search: - The Web - Images - News - Blogs - Shopping Parkinson's disease Dictionary Par·kin·son's disease p¤r kÄ­n-sənz n. A progressive nervous disease occuring most often after the age of 50, associated with the destruction of brain cells that produce dopamine and characterized by muscular tremor, slowing of movement, partial facial paralysis, peculiarity of gait and posture, and weakness. Also called paralysis agitans shaking palsy [After James Parkinson (1755–1824), British physician.] Encyclopedia Parkinson's disease or Parkinsonism, degenerative brain disorder first described by the English surgeon James Parkinson in 1817. When there is no known cause, the disease usually appears after age 40 and is referred to as Parkinson's disease. Parkinsonism usually refers to similar symptoms resulting from head injury, encephalitis, syphilis, carbon monoxide poisoning, cerebral arteriosclerosis, or use of MPTP (a synthetic narcotic). The disorder is also termed paralysis agitans, or shaking palsy. Parkinson's disease is a debilitating and progressive disorder in which the chemicals that facilitate electrical transmission between nerve cells are depleted. It was the first disease to be treated by drugs that replace deficient

118. Parkinson's Disease: Is Victory In Sight? Comprehensive review of the latest research into Parkinson s disease with emphasison prevention and complementary and alternative treatments. http://vvv.com/HealthNews/dparrewb.html

Comprehensive review of the latest research into Parkinson's disease with emphasis on prevention and complementary and alternative treatments Parkinson's Disease: Is Victory in Sight? by Hans R. Larsen, MSc ChE If research into Parkinson's disease continues at its present pace this dreaded disease may well be fully understood and largely preventable early in the 21st Century. Parkinson's disease ( paralysis agitans , shaking palsy) was first described in 1817. L-dopa, the mainstay of current drug therapy was introduced in 1970 and since then hundreds of research papers have been published on the disease. It is now increasingly clear not only what causes Parkinson's, but also how it can be prevented and its relentless progress slowed down. Incidence and Symptoms Idiopathic (of no known cause) Parkinson's disease affects about one percent of the population over the age of 60 years in the United States. It is more common among men than among women and also seems to be more widespread in northern countries. The incidence of the disease increases with age although aging itself is not believed to be a causative factor. Parkinson's disease is rarely inherited and less than one per cent of all cases are thought to have a genetic component. At this time there is no medical cure for the condition, but drugs that alleviate the symptoms and slow the progress of the disease are available(1-5). The main symptom of Parkinson's disease is a pronounced tremor affecting the extremities notably the hands, chin or lips. The tremor is most evident at rest and disappears with movement. Other characteristic symptoms of Parkinson's disease are stiffness or slowness of movement, a shuffling walk, stooped posture, and difficulties in performing simple tasks. Memory impairment and cognitive dysfunction are rarely encountered in early stage Parkinson's disease. Depression is, however, a common feature and about 30 per cent of Parkinson's disease victims eventually develop Alzheimer's disease or other forms of dementia(1-3,6-8).

119. Parkinson's Disease And Glutathione (GSH) Glutathione (GSH) deficiency in Parkinson s disease and its treatment withantioxidants. http://www.1whey2health.com/parkinsons_glutathione.htm

Glutathione (GSH) in the etiology and treatment of Parkinson's Disease Reproduction Prohibited What is Parkinson's Disease? What is the role of Dopamine? Why are Antioxidants important? How does Glutathione therapy help in Parkinson's Disease? ... Research Abstracts on Glutathione and Parkinson's Disease What is Parkinson's Disease? Parkinson's Disease (PD) is named after Dr. James Parkinson, a London physician who is credited with being the first to describe this disease in 1817. According to the National Parkinson Foundation ( www.parkinson.org ), PD is a slowly progressing disease of the nervous system. Occurring in one out of every 100 individuals over 65 years of age, PD results in progressive neurodegeneration that ends in death, due primarily to secondary complications such as infection. PD involves a selective loss of neurons in an area of the midbrain called the substantia nigra. One of the mechanisms contributing to neuron loss in the substantia nigra is damage by reactive oxygen species

120. InteliHealth: Parkinson's Disease InteliHealth Featuring Harvard Medical School s consumer health information.For more than 550 diseases and conditions, learn What Is It?, Symptoms, http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/11072.html

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