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         Ollier Disease:     more detail
  1. Molecular Profiling of Solitary and Ollier Disease-related Central Chondrosarcomas: An Investigation of DNA Aberrations, mRNA and Protein Expression by Leida B. Rozeman, 2005
  2. Allergy: The Facts (Oxford Medical Publications) by Robert J. Davies, Susan Ollier, 1989-05-18

81. Ollier's Disease. An Assessment Of Angular Deformity, Shortening, And Pathologic
A retrospective review of twentyone patients with ollier s disease showed thatthe lesion involved the femur and tibia most frequently, and that those
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JOURNAL ARTICLE
Ollier's Disease. An assessment of angular deformity, shortening, and pathological fracture in twenty-one patients
F Shapiro
A retrospective review of twenty-one patients with Ollier's disease showed that the lesion involved the femur and tibia most frequently, and that those bones accounted for the large majority of clinical problems. Angular deformities were common; 80 per cent of the affected femora had clinically significant varus or valgus angulation in the distal part and 42 per cent of the affected tibiae had proximal or distal deformity. The apex of the

82. Ollier's Disease - Definition Of Ollier's Disease In The Medical Dictionary - By
Definition of ollier s disease in the Medical Dictionary and Thesaurus.ollier s disease explanation. Information about ollier s disease in Free online
http://medical-dictionary.thefreedictionary.com/Ollier's disease
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Ollier's disease
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Cite / link Email Feedback Ol·lier's disease l z , ô-ly z n. See enchondromatosis Mentioned in No references found Medical browser Full browser olivary body olivary nucleus olive olivifugal ... olivopontocerebellar atrophy Ollier's disease Ollier-Thiersch graft OM omalizumab omega ... Ollie, Iowa Ollier's disease Ollier-Thiersch graft Ollila, Jorma Jaakko Ollivander's Ollivander's Wand Shop ... Ölme Hundred Word (phrase): Word Starts with Ends with Definition Free Tools: For surfers: Browser extension Word of the Day NEW! Help For webmasters: Free content NEW! Linking Lookup box ... Farlex, Inc. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.

83. Entrez PubMed
Multiple enchondromatosis (ollier s disease) is a nonhereditary disease characterizedby multiple ce
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

84. Portal Toolkit Invalid Site URL
Chondrosarcoma of bone complicating ollier s disease Report of a favourable ollier s disease or multiple enchondromatosis is a rare, nonhereditary
http://ppv.ovid.com/pt/re/ausr/fulltext.00000938-200309000-00022.htm
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85. Portal Toolkit Invalid Site URL
Chondrosarcoma of bone complicating ollier s disease Report of a favourableresponse to radiotherapy. Australasian Radiology. 47(3)322324, September 2003
http://ppv.ovid.com/pt/re/ausr/abstract.00000938-200309000-00022.htm
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86. Ollier's Disease - Patient UK
ollier s disease Patient UK. A directory of UK health, disease, illness andrelated medical websites that provide patient information.
http://www.patient.co.uk/showdoc/40001121/
PatientPlus articles are written for doctors and so the language can be technical. However, some people find that they add depth to the articles found in the other sections of this website which are written for non-medical people.
Ollier's disease
A form of enchondroma. These are benign lesions of hyaline cartilage found in the centre of bone. Singly they are usually asymptomatic and found in the hand. In Ollier's disease there is multifocal involvement that can cause bony dysplasia resulting in diminished stature, deformed joints and limbs of dissimilar lengths. Presentation
Signs
Pathological fractures Investigations X-ray - radiolucent, sharply marginated lesions occupying medullary canal. More commonly in adults may be stippled or punctate calcifications within lesions. Management
Surgical
In problem lesions curettage and bone grafting. Correction of joint deformities. Associated diseases Glioma References Used
  • Nelson Textbook of Pediatrics. 16th Edition. Behrman RE et al. WB Saunder Co. 2000.
  • Jesus-Garcia R, Bongiovanni JC, Korukian M, et al
  • 87. Clinical Orthopaedics And Related Research - UserLogin
    Multiple enchondromatosis, or ollier s disease, is a nonhereditary bone defect, The term ollier s disease is used to describe a condition with
    http://www.corronline.com/pt/re/corr/fulltext.00003086-200101000-00013.htm
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    88. Clinical Orthopaedics And Related Research - Abstract: Volume (382) January 2001
    the Ilizarov External Fixator in the Treatment of Patients With ollier s disease . of 10 patients with ollier s disease using the Ilizarov technique.
    http://www.corronline.com/pt/re/corr/abstract.00003086-200101000-00013.htm
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    PDF (155 K) Use of the Ilizarov External Fixator in the Treatment of Patients With Ollier's Disease.
    Jesus-Garcia, Reynaldo MD; Bongiovanni, Jose Carlos MD; Korukian, Marcos MD; Boatto, Hilario MD; Seixas, Maria Teresa MD; Laredo, Jose MD Abstract:
    The authors present the results of treatment of 10 patients with Ollier's disease using the Ilizarov technique. The Ilizarov device was used to treat leg length discrepancy and to enhance the conversion of chondroma cartilage into normal mature bone, with no curettage and bone grafting. The mean duration of treatment was 9.4 months. This technique was highly efficient in treating the disease. It led to conversion of the abnormal cartilage into histologically mature bone in all patients. Some complications were seen, such as decreased knee mobility, which required prolonged use of the device. The Ilizarov technique is successful in treating patients with Ollier's disease despite some complications and the difficulty in using the technique.
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    89. Pathology Case Reviews - Fulltext: Volume 6(1) January/February 2001 P 8-13 Dist
    In the short tubular bones of the hands and feet and in ollier s disease,enchondromas do grow. Therefore, the threshold for regarding central cartilage
    http://www.pathologycasereviews.com/pt/re/pathcr/fulltext.00132583-200101000-000
    LWWOnline LOGIN eALERTS REGISTER ... Archive Distinguishing Enchondroma From... ARTICLE LINKS:
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    PDF (1.1 M) References (7) Permissions ... View full size inline images Pathology Case Reviews Volume 6(1) January/February 2001 pp 8-13
    Distinguishing Enchondroma From Low-Grade Central Chondrosarcoma
    McCarthy, Edward F. MD; Tyler, Wakenda K. BA From the Department of Pathology and Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Address correspondence and reprint requests to Edward F. McCarthy, MD, Department of Pathology and Orthopaedic Surgery, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287 (e-mail: mccarthy@jhmi.edu). Article Outline Figures/Tables
    Abstract TOP
    Distinguishing enchondroma from low-grade central chondrosarcoma depends on interpreting histologic findings in the light of clinical and radiologic features. In the long bones, enchondromas do not grow, whereas low-grade chondrosarcomas grow slowly. The distinction should be made based on answers to the question, Is the lesion growing? Serial radiographs are the best way to answer this question. Other clues are present in the clinical, radiographic, and histologic findings. In the short tubular bones of the hands and feet and in Ollier's disease, enchondromas do grow. Therefore, the threshold for regarding central cartilage lesions in these settings should be higher. Extreme cortical expansion and/or infiltration of soft tissues should be present to diagnose chondrosarcoma.

    90. Musculoskeletal Diseases
    About Echondromatosis, Multiple (ollier and Maffucci diseases) OMIM (US).ollier s disease Self Help Group, UK. Fibrous Dysplasia of Bone
    http://www.mic.ki.se/Diseases/C05.html
    search search staff sitemap
    ABOUT KAROLINSKA INSTITUTET
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    Diseases and Disorders Links pertaining to Musculoskeletal Diseases Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Achondroplasia Achondroplasia Acquired Hyperostosis Syndrome Acrocephalosyndactylia ... Tietze's Syndrome
    Musculoskeletal Diseases Textbook of Orthopaedics [CR Wheeless] Educational textbook syllabus [Borrill et al.] - Orthoteers (UK) The Belgian OrthoWeb - (BE) Site Map of the Orthopaedics and Sports Medicine resource at Univ of Washington, Seattle (US) The American Academy of Orthopaedic Surgeons A Musculoskeletal Atlas , an illustrated Musculoskeletal Glossary , and a set of educational cases (radiol.) - U of Washington (US) Ortho Supersite OrthoLinx WorldOrtho including A Simple Guide to Orthopaedics [RL Huckstep] - Nepean Hosp., Sydney (AU) A collection of Case discussions at OrthoGate.org

    91. Annals Of Plastic Surgery - UserLogin
    Miyawaki T, Kinoshita Y, Iizuka T. A case of ollier s disease of the hand.Ann Plast Surg 1997; Bone sarcomas associated with ollier s disease.
    http://www.annalsplasticsurgery.com/pt/re/annps/fulltext.00000637-200108000-0002
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    92. IngentaConnect Chondrosarcomas Of The Base Of The Skull In Olliers Disease Or Ma
    ollier s disease is a rare disease characterized by constitutional bone dysplasiawith multiple enchondromas. The combination of haemangioma and
    http://www.ingentaconnect.com/content/tandf/sonc/2004/00000043/00000008/art00002

    93. UW MSK Resident Projects : Enchondromas And Related Disorders
    ollier s disease is a rare developmental disorder characterized by enchondroma The enchondromas of ollier s disease may have different radiographic
    http://uwmsk.org:8080/residentprojects/stories/storyReader$223
    UW MSK Resident Projects University of Washington, UWMC Roosevelt Clinic, Musculoskeletal Radiology Home About Membership Join Now Login
    Enchondromas and Related Disorders
    Print-friendly version of this page Posted by Jeffrey P. Kanne , 5/17/04 at 8:52:19 AM. What are they? Enchondromas are benign cartilaginous neoplasms that originate in the medullary canal of tubular bones, believed to result from growth of residual benign cartilage rests displaced from the physis. They are often incidental findings, occurring in just under 2% of the population based on autopsy series. Where do they occur? Approximately half of all enchondromas occur in the tubular bones of the hands and feet, with others are found in the metaphyses of other long bones. They rarely occur in the pelvis, shoulder girdle, and axial skeleton. What do they look like? Radiographically, enchondromas appear as geographic, mildly expansile, lytic lesions, which may lead to mild cortical thinning. The zone of transition is narrow, although it can be lobular. A cartilaginous matrix (rings and arcs) is often present, less often in lesions occurring in the hands and feet.

    94. Journal Of Pediatric Orthopaedics - UserLogin
    Between 1997 and 2001 three children with ollier s disease underwent treatmentof five The term ollier s disease refers to cases of dyschondroplasia or
    http://www.pedorthopaedics.com/pt/re/jpedortho/fulltext.00004694-200503000-00015
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    95. Journal Of Pediatric Orthopaedics - UserLogin
    ollier s disease Varus Angulation at the Lower Femur and Its Management ollier s disease is an uncommon disorder believed to be the result of
    http://www.pedorthopaedics.com/pt/re/jpedortho/fulltext.00004694-199803000-00013
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    96. Tumors ChondrosarcID5063
    While most enchondromas are solitary, patients with ollier s disease and Maffucci ssyndrome demonstrate multiple enchondromas.
    http://www.infobiogen.fr/services/chromcancer/Tumors/chondrosarcID5063.html
    Atlas of Genetics and Cytogenetics in Oncology and Haematology
    Home Genes Leukemias Solid Tumours ... NA
    Bone: Chondrosarcoma
    Identity Figure 1: En bloc resection specimen of the proximal fibula of a 43 year old female, containing a lobulated bluish white, translucent tumour (4.5 x 2 x 1.9 cm) located centrally within the medullary cavity, consistent with central chondrosarcoma
    Figure 2: Corresponding macro-slice showing a lobular architecture, and endosteal cortical thinning. Cytonucle ar appearance can be more readily appreciated in figure 3 Classification Note approximately 90% of chondrosarcomas are histologically of the conventional type; in addition to conventional chondrosarcoma, some rare variants with distinctive microscopic and clinical features are discerned: clear cell chondrosarcoma (1%), mesenchymal chondrosarcoma (2%), juxtacortical chondrosarcoma (2%) and extra-skeletal myxoid chondrosarcoma (5%). Furthermore, dedifferentiated chondrosarcoma is a relatively rare high grade sarcoma next to a low-grade conventional malignant cartilage-forming tumor, comprising 6-10% of all chondrosarcomas. Conventional chondrosarcomas can be categorized according to their location in bone. The majority of chondrosarcomas (75%) are located centrally within the medullary cavity (central chondrosarcoma), a small percentage of which arise within a preexisting benign precursor (enchondroma). While most enchondromas are solitary, patients with Ollier's disease and Maffucci's syndrome demonstrate multiple enchondromas.A minority (15%) of chondrosarcomas develops from the surface of bone (peripheral chondrosarcoma) as a result of malignant transformation within the cartilaginous cap of a solitary or hereditary pre-existent osteochondroma.

    97. The American Journal Of Surgical Pathology - UserLogin
    A 63year-old man with a known history of ollier s disease underwent a right Patients with ollier s disease are at higher risk for development of
    http://www.ajsp.com/pt/re/ajsp/fulltext.00000478-199603000-00005.htm
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    98. Disease Organizations;  Patient Support And Education
    ollier s disease, Maffucci s syndrome, and their families. ollier/Maffucci sSelf Help Group Mission is to help as many individuals with these
    http://www.voice4patients.com/patient services.htm
    Empowering Patients
    To Be
    Their Own
    Health Care Advocates
    Voice4Patients.Com
    PO Box 273
    Warren, ME. 04864
    www.voice4patients.com
    voice4patients@aol.com

    National Support Services
    PULSEAmerica.Org
    Patient Support and Education encourages patients to learn as much as possible about their illness, disease or condition. On this page, is an extensive list of disease specific organizations who offer consumer support, resources and education. It is critical that you bring the information you receive to the attention of your treating health care provider(s). Share the data and have it validated by the provider(s). The resources of this list are intended to be "Building Blocks" to encourage communication between you the patient, and your provider. They are not a substitute for the expertise of a trained clinician. To research your illness, disease or condition: www.voice4patients.com/research Acoustic Neuroma Down Syndrome Liver ... MISC. Alphabetical Listing Disease Organizations Acoustic Neuroma Assocation 600 Peachtree Pkwy, Suite 108

    99. Bone Disease Hereditary Bone Disease Metabolic Bone Disease
    Multiple forms (ollier s disease) increases the risk for malignant transformation.Cartilaginous Tumors Malignant Chondrosarcoma This cartilage producing
    http://www.geocities.com/CollegePark/Classroom/9056/bone.html
    Bone Disease Hereditary bone disease Metabolic bone disease Infectious bone disease Bone tumors Hereditary bone disease Diseases of abnormal growth plate maturation (osteochondrodysplasia).
      Achondroplasia Osteogenesis Imperfecta (OI) This condition represents a group of inheritable disorders caused by abnormal type I collage synthesis. Aberrant collagen deposition in osteoid synthesis leads to "brittle bones". This condition may confuse social and health care workers in cases of potential child abuse. Clinical: Type I (A.D.) Multiple fractures in infancy. Blue sclera Poor dentition Hearing loss Kyphoscoliosis Type II (A.R.) Perinatal death Osteopetrosis (Marble bone disease of Albers-Schonberg) . Rare disease inheritable as either dominant or recessive trait. Recessive form is fatal during neonatal/infant stage. Clinical: Cortical overgrowth Pathologic fractures Anemia Cranial nerve entrapment Prognosis: Variable with bone marrow transplant. Metabolic Disease Osteoporosis Rickets/Osteomalacia Hyperparathyroidism This condition results from excessive PTH release. The primary form results from hyperplastic parathyroid tissue. The secondary form is typically a consequence of renal failure. Unchecked PTH release stimulates osteoclasts to resorb bone. Patients suffer from changes ocurring in bone and from the hypercalcemia that develops. Clinical: Osteitis fibrosa cystica Brown tumor Hypercalcemia Pathologic fractures

    100. Health Information Resource Database: American Association Of Multiple Enchondro
    research and services for adults and children with enchondromatosis, multipleenchondroma, ollier s disease, Maffucci s syndrome, and their families.
    http://www.health.gov/NHIC/NHICScripts/Entry.cfm?HRCode=HR3623

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