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         Ollier Disease:     more detail
  1. Molecular Profiling of Solitary and Ollier Disease-related Central Chondrosarcomas: An Investigation of DNA Aberrations, mRNA and Protein Expression by Leida B. Rozeman, 2005
  2. Allergy: The Facts (Oxford Medical Publications) by Robert J. Davies, Susan Ollier, 1989-05-18

1. NORD - National Organization For Rare Disorders, Inc.
Sample report, plus links to organisations. Fee required for full report
http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Ollier Diseas

2. Ollier Disease
As with ollier disease, there is typically a shortening of the long bones.These patients are at higher risk for sarcomatous transformation of both the
http://www.stevensorenson.com/residents6/ollier_disease.htm

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Up Neurofibromatosis Pyknodysostosis ... Multiple hereditary exostoses [ Ollier disease ] Achondroplasia Diastrophic dwarfism Chondrodysplasia punctata Thanatophoric dwarfism ... Dyschondrosteoses Enchondromatosis, or multiple enchondromas, refers to a group of disorders of which Ollier disease is the best known. This is nonhereditary disorder which usually presents in childhood. Nominally, the disease consists of multiple enchondromas. However, on radiographs, streaks of low density are seen projecting through the diaphyses into the epiphyses of the long bones, due to ectopic cartilage deposits. With age, the cartilage may calcify in the typical "snowflake" pattern. The affected extremity is shortened (asymmetric dwarfism) and sometimes bowed due to epiphyseal fusion anomalies. Patients are at risk for development of sarcomas, specifically osteosarcomas and chondrosarcomas. These occur in approximately 25 % of patients. Mafucci syndrome represents enchondromatosis with oft tissue hemangiomas, usually in the hands and feet. As with Ollier disease, there is typically a shortening of the long bones. These patients are at higher risk for sarcomatous transformation of both the vascular and cartilaginous portions of the disease. REFERENCES Flemming DJ, Murphey MD. Enchondroma and chondrosarcoma. Semin Musculoskelet Radiol. 2000;4(1):59-71.

3. Ollier Disease
ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia). While this disorder may be present at
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. Ollier Disease
Pyknodysostosis Mucopolysaccharidoses Multiple hereditary exostoses ollier disease Achondroplasia Diastrophic dwarfism
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5. Ollier Disease
a CHORUS notecard document about ollier disease
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. Ollier Disease
ollier disease is a rare skeletal disorder characterized by abnormal bonedevelopment (skeletal dysplasia). While this disorder may be present at birth
http://www.bchealthguide.org/kbase/nord/nord337.htm
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National Organization for Rare Disorders, Inc.
Ollier Disease
Important
It is possible that the main title of the report Ollier Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
  • Multiple Enchondromatosis Multiple Cartilaginous Enchondroses Dyschondroplasia Enchondromatosis
Disorder Subdivisions
  • None
General Discussion
Ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia). While this disorder may be present at birth (congenital); it may not become apparent until early childhood when symptoms, such as deformities or improper limb growth, are more obvious. Ollier disease primarily affects the long bones and cartilage of the joints of the arms and legs, specifically the area where the shaft and head of a long bone meet (metaphyses). The pelvis is often involved; and even more rarely, the ribs, breast bone (sternum), and/or skull may also be affected.
Ollier disease manifests as greater than normal growth of the cartilage in the long bones of the legs and arms so that growth is abnormal and the outer layer (cortical bone) of the bone becomes thin and more fragile. These masses of cartilage are benign (non-cancerous) tumors known as enchondromas. Enchondromas may occur at anytime. After puberty these growths stabilize as cartilage is replaced by bone. In rare cases, the enchondromas may undergo malignant changes (e.g., chondrosarcomas). The exact cause of Ollier disease is not known, although in some cases it may be inherited as an autosomal dominant genetic trait.

7. Ollier's Disease (Dyschondroplasia, [Multiple] Enchodromatosis
Ollier's Disease (Dyschondroplasia, Multiple Hereditary Enchodromatosis, Osteochondromatosis)
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Ollier Disease
a CHORUS notecard document about ollier disease. ollier disease. multipleenchondromata; hamartomas of cartilage within bone
http://chorus.rad.mcw.edu/doc/00292.html
CHORUS Collaborative Hypertext of Radiology Musculoskeletal system About CHORUS
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Ollier disease
  • multiple enchondromata
  • hamartomas of cartilage within bone
  • may be limited to one extremity or to extremities of one side
  • femur + tibia most often involved
  • may degenerate > chondrosarcoma
Cf: Mafucci syndrome Charles E. Kahn, Jr., MD - 2 February 1995
Last updated 26 May 2004
Related CHORUS documents:
enchondroma Mafucci syndrome chondrosarcoma hemangioma of bone ... fibrous dysplasia
Search for related articles:
AJR American Journal of Roentgenology PubMed : index to biomedical literature ...

Medical College of Wisconsin

9. Multiple Enchondroma Diseases / Family Village
Maffucci Syndrome from eMedicine Ollier's Disease About Enchondroma Diseases Dyschondroplasia Ollier's Disease and Maffucci's Disease
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. Ollier Disease
ollier disease. multiple enchondromata; hamartomas of cartilage within bone.may be limited to one extremity or to extremities of one side
http://chorus.rad.mcw.edu/to-go/00292.html
Ollier disease
  • multiple enchondromata
  • hamartomas of cartilage within bone
  • may be limited to one extremity or to extremities of one side
  • femur + tibia most often involved
  • may degenerate > chondrosarcoma
Cf: Mafucci syndrome Home Musculoskeletal system

11. Virtual Children's Hospital Paediapaedia Enchondromatosis
In later stages of the disease the lesions are more frequently linear or striated.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. Ollier Disease
ollier disease is a rare skeletal disorder characterized by abnormal bonedevelopment (skeletal dysplasia).
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Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report Ollier Disease Important It is possible that the main title of the report Ollier Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms
  • Multiple Enchondromatosis Multiple Cartilaginous Enchondroses Dyschondroplasia Enchondromatosis
Disorder Subdivisions
  • None
General Discussion Ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia). While this disorder may be present at birth (congenital); it may not become apparent until early childhood when symptoms, such as deformities or improper limb growth, are more obvious. Ollier disease primarily affects the long bones and cartilage of the joints of the arms and legs, specifically the area where the shaft and head of a long bone meet (metaphyses). The pelvis is often involved; and even more rarely, the ribs, breast bone (sternum), and/or skull may also be affected. Ollier disease manifests as greater than normal growth of the cartilage in the long bones of the legs and arms so that growth is abnormal and the outer layer (cortical bone) of the bone becomes thin and more fragile. These masses of cartilage are benign (non-cancerous) tumors known as enchondromas. Enchondromas may occur at anytime. After puberty these growths stabilize as cartilage is replaced by bone. In rare cases, the enchondromas may undergo malignant changes (e.g., chondrosarcomas). The exact cause of Ollier disease is not known, although in some cases it may be inherited as an autosomal dominant genetic trait.

13. EMedicine - Enchondroma And Enchondromatosis Article By Felix S
In ollier disease, enchondromas often appear to be larger than they do in other conditions.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. OLLIER DISEASE : Contact A Family - For Families With Disabled Children: Informa
Contact a Family is a UK charity for families with disabled children. We offerinformation on specific conditions and rare disorders.
http://www.cafamily.org.uk/Direct/o12.html
printer friendly OLLIER DISEASE home how we can help medical information index of conditions ... how you can help Did you find this page
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yes no Ollier disease: Enchondromatosis An Enchondroma is an island of unossified hyaline cartilage situated within bone (cartilage is the precursor of bone). They are usually multiple, affecting one or several bones. Characteristically, it is an asymmetric disorder, confined to one side of the body. The bones most commonly affected are the long bones, pelvis and bones of the hand. The islands of cartilage appear early in childhood and can develop, but it is very unusual for additional lesions to appear after puberty. Ollier disease is a very rare disorder which affects both sexes. It presents either as a lump or swelling or deformity of the long bone in early childhood. As the bones are weakened, they may fracture but healing is normal. The severity varies but otherwise the child develops normally. The main complications are the nature of the lump or swelling, the deformity of the affected bone and the shortening of the affected bone. The deformity can be corrected by osteotomy and the shortening can be addressed by leg lengthening in the knowledge that the bones will heal normally. Differential diagnoses of fibrous dysplasia and diaphyseal aclasis need to be considered. It is recognised that malignancy can occur but it is extremely rare. Maffucci syndrome in which there are cutaneous haemangionates associated with the enchondromas does carry a definite risk of malignancy. However, this is a separate and even rarer condition.

15. EHLERS-DANLOS SYNDROME ASSOCIATED WITH OLLIER DISEASE14(3)
EHLERSDANLOS SYNDROME ASSOCIATED WITH ollier disease. Mohammed Moussa, MCh(Ortho), PhD; Anwar Ul-Haque, FCAP; Ake Ahlberg, PhD
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16. AAMED American Association Of Multiple Enchondroma Diseases
General Information Score 0) Clinical Information The Management of Leglength Discrepancy in Ollier's Disease with a Fully Implan
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. OLLIER DISEASE Contact A Family - For Families With Disabled
printer friendly ollier disease search this site home how we can help medical information index of conditions about the
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18. Ollier Disease Definition - Medical Dictionary Definitions Of Popular Medical Te
Online Medical Dictionary and glossary with medical definitions.
http://www.medterms.com/script/main/art.asp?articlekey=11765

19. Ollier Disease - International Center For Limb Lengthening - Rubin Institute For
ollier disease Sinai Hospital Maryland. Find a Physician, ollier disease.LifeBridge Health Quick Links, LifeBridge Health ..Community Calendar .
http://www.lifebridgehealth.org/2370.cfm
Ollier Disease LifeBridge Health Quick Links LifeBridge Health ..Community Calendar ..Giving Opportunities ..Careers at LifeBridge ..Medical Services ..News ..Volunteering ..Health Buzz ..Site Map ..Site Search ..Contact LifeBridge Health Sinai Hospital ..Directions to Sinai Hospital ..Children's Hospital at Sinai ..Graduate Medical Education ..VSP ..Centers Of Excellence -Medical Services- ..Addictions Recovery Program (SHARP) ..Anesthesia ..CyberKnife� Center ..Emergency Medicine (ER-7) ..Heart Center ..International Center for Limb Lengthening ..Krieger Eye Institute ..Medicine ..Oral Surgery and Dentistry ..Otolaryngology ..Pathology ..Psychiatry ..Radiation Oncology ..Radiology ..Rehabilitation Center ..Rubin Institute for Advanced Orthopedics ..Sleep Center ..Spine Center ..Stroke Center ..Surgery ..Urology ..Volunteering ..Women's Services ..Nursing at Sinai ..Sinai Auxiliary ..Patient E-Cards ..Sinai Gift Shop ..Contact Sinai
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20. Ollier Disease - International Center For Limb Lengthening - Rubin Institute For
ollier disease International Center for Limb Lengthening Rubin Institute forAdvanced Orthopedics at Sinai Hospitals of Baltimore.
http://www.lifebridgehealth.org/sinaibody.cfm?id=2027

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