81. Journal Of Bone And Joint Surgery: Spontaneous Tendon Ruptures In Alkaptonuria ochronosis, the musculoskeletal manifestation of alkaptonuria, is known to lead to The patient had no previous symptoms related to ochronosis. http://www.findarticles.com/p/articles/mi_qa3767/is_200308/ai_n9239086

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles Journal of Bone and Joint Surgery Aug 2003 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Spontaneous tendon ruptures in alkaptonuria Journal of Bone and Joint Surgery Aug 2003 by Kumar, R V Manoj Rajasekaran, S Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. Received 5 July 2002; Accepted after revision 16 December 2002 Ochronosis, the musculoskeletal manifestation of alkaptonuria, is known to lead to degenerative changes of the spine and weight-bearing joints. Symptoms related to degeneration of tendons or ligaments with spontaneous ruptures have not previously been reported. Three patients are described with four spontaneous ruptures of either the patellar tendon or tendo Achillis as the first symptom of alkaptonuria. Alkaptonuria is a rare autosomal recessive metabolic disorder due to deficiency of the enzyme homogentisic acid oxidase which is involved in the metabolism of homogentisic acid, a metabolic product of the aromatic amino acids phenylalanine and tyrosine.1 The homogentisic acid which accumulates is polymerised to form a dark pigment which is deposited in connective tissues. The pigment is also selectively deposited in the hyaline cartilage of major peripheral joints and intervertebral discs leading to early degeneration and arthritis. Apart from pigmentation of the skin, sclera and the pinnae, systemic symptoms related to the genitourinary, cardiovascular and respiratory systems have also been described.2

82. Cardiac Ochronosis Pathologic examination of the aortic leaflets revealed ochronosis (Fig. In conclusion, cardiac ochronosis is a very rare disease, but cardiac surgeons http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=548253

83. Alkaptonuric Ochronosis With Aortic Valve And Joint Replacements And Femoral Fra A diagnosis of ochronosis was made by radiological exam, The earliest verifiedcase of ochronosis was described in an Egyptian mummy dating to 1500 BC http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1069096

84. Argyria Localized argyria with pseudoochronosis. Leslie Robinson-Bostom, MD Ochre swollen homogenized collagen bundles resembling ochronosis have not been http://www.thedoctorsdoctor.com/diseases/argyria.htm

Background This is a rare and unusual complication of silver salts deposited in the skin and internal organs. OUTLINE Epidemiology Disease Associations Pathogenesis Laboratory/Radiologic/ ... Internet Links EPIDEMIOLOGY CHARACTERIZATION INCIDENCE Rare ACUPUNCTURE Blue macules of localized argyria caused by implanted acupuncture needles. Electron microscopy and roentgenographic microanalysis of deposited metal. Tanita Y, Kato T, Hanada K, Tagami H. Arch Dermatol 1985 Dec;121(12):1550-2 Abstract quote Acupuncture needles implanted in the skin for more than ten years caused peculiar bluish macules, each of which clinically resembled a blue nevus in the extremities of a 63-year-old Japanese woman. Histologically, the involved skin showed deposition of fine brownish granules in the basement membrane of the eccrine sweat glands, on the inner surface of the blood vessel walls, and along elastic fibers of the superficial dermis in addition to sparse deposits noted throughout the dermis. Electron microscopy revealed deposits of electron-dense particles on the basal lamina of the secretory coils of the eccrine sweat glands, below the basal lamina of the dermoepidermal junction, and on elastic fibers.

85. Karger Publishers A deficiency of HGAO induces homogentisic aciduria, ochronosis and arthritis 2 ochronosis is not limited to alkaptonuria and can be caused by several http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ProduktNr=

86. Alkaptonuria AKU. Homogentisic acid oxidase deficiency. ochronosis, hereditary. Painted black Painted black Ocular ochronosis in alkaptonuria patients carrying http://www.gfmer.ch/genetic_diseases_v2/gendis_detail_list.php?cat3=18

87. Gms | | Ocular Ochronosis (Alkaptonury) Ocular ochronosis (Alkaptonury) globe rupture after blunt trauma. correspondingauthor K. AlSamir - University Eye Clinic Hamburg-Eppendorf http://www.egms.de/en/meetings/dog2004/04dog691.shtml

Home About Contact Imprint ... German 102. Jahrestagung der DOG Deutsche Ophthalmologische Gesellschaft e.V. 23. bis 26.09.2004, Berlin published by Meeting DOG 2004 Search DOG 2004 Email this Article Output Options XML Meeting Abstract Ocular ochronosis (Alkaptonury): globe rupture after blunt trauma K. Al-Samir - University Eye Clinic Hamburg-Eppendorf U. Schaudig - University Eye Clinic Hamburg-Eppendorf The electronic version of this article is the complete one and can be found online at: Published: Search Medline for Al-Samir K Schaudig U Outline Top Text Text Methods Results Microscopic findings of the brownish pigmentation: Normal conjunctival epithelium, extracellular brown plaque-like structures similar to pigmentations. These pigmentations varied in size and were found most often next to vessels. On a second look the patient showed remarkable brown skin colour and very dark ears. Conclusions AWMF DIMDI ZB MED

88. Alkaptonuria - Descipher Health ochronosis Terms and Definitions at www.MedicalGlossary.orgochronosis Definitions and Terms. MedicalGlossary.org is designed as a free,browsable resource for all. The medical terms and definitions are not intended http://www.descipher.com/health/info/Ochronosis

Do you have lab results? Alkaptonuria From Descipher Health (Redirected from Ochronosis Description: Table of contents showTocToggle("show","hide") 1 Synonyms 2 Cause 3 Population Distribution 4 Effects ... edit Synonyms ochronosis, homogentisic acid oxidase deficiency edit Cause edit Population Distribution edit Effects edit Symptoms edit Signs edit Diagnostic Tests edit Differential Diagnosis edit Treatment edit Expected Outcome edit Prevention edit Medical References edit External Links Retrieved from " http://www.descipher.com/health/info/Alkaptonuria Views Article Discussion Edit History Personal tools Create an account or log in Check Lab Results Diseases Labs ... Terms of Service This work is licensed under a Creative Commons License . Please email webmaster@descipher.com with any comments you may have.

89. Bioline International Official Site (site Up-dated Regularly) She was diagnosed to have ochronosis and was positive for urine HPLC (high profile Our case report highlights unusual cutaneous signs of ochronosis. http://www.bioline.org.br/request?ms05031

90. OCHRONOSIS Meaning And Definition - Dictionary - ELook.org Alkaptonuric ochronosis and multiple intracranial aneurysms.Alkaptonuric ochronosis is a heritable disorder of tyrosine metabolism, withvarious systemic abnorm http://www.elook.org/dictionary/ochronosis.html

eLook Home eLook Online Dictionary Search Online Dictionary More Resources Information US City Data Worldwide Weather Entertainment Video Game Cheats Food Nutrition Recipes Literature Literature Reference Computing Dictionary Internet Encyclopedia Programming Reference ... Thesaurus By Letter: Non-alphabet A B C ... Email this page to a friend OCHRONOSIS Definition: [noun] an accumulation of dark pigment in cartilage and other connective tissue; usually a symptom of alkaptonuria or phenol poisoning Synonyms: Search for synonyms for OCHRONOSIS eLook Home eLook Online Dictionary Search Online Dictionary ... Contact

91. Entrez PubMed Ochre swollen homogenized collagen bundles resembling ochronosis have not beenpreviously described. OBJECTIVE The purpose of this study is to report a http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2

92. Aortic Valve Replacement In Cardiac Ochronosis -- Kim And Daenen 6 (11): 625 -- Two patients with generalized ochronosis developed cardiovascular symptoms relatedto cardiac ochronosis with aortic valvular stenosis. http://ejcts.ctsnetjournals.org/cgi/content/abstract/6/11/625

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Kim, Y. I. Articles by Daenen, W. ARTICLES Aortic valve replacement in cardiac ochronosis YI Kim and W Daenen Department of Cardiac Surgery, University Hospital, Gasthuisberg, Leuven, Belgium. Two patients with generalized ochronosis developed cardiovascular symptoms related to cardiac ochronosis with aortic valvular stenosis. One patient with a transvalvular pressure gradient of 150 mm Hg underwent emergency aortic valve replacement. The other patient with a transvalvular pressure gradient of 96 mm Hg underwent successful elective aortic valve replacement. Cardiac ochronosis is a rare disease that might be encountered, with the typical signs, during an elective, planned cardiac

93. Ochronosis Of The Aorta -- Ghotkar Et Al. 23 (3): 423 -- European Journal Of Car Corresponding author. Tel. +44151-293-2391; fax +44-151-293-2254 e-mailvishvsanjay@hotmail.com. Key Words Alcaptonuria • ochronosis • Aortic stenosis http://ejcts.ctsnetjournals.org/cgi/content/extract/23/3/423

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Full Text Full Text (PDF) Alert me when this article is cited ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Ghotkar, S. Articles by Dihmis, W. Related Collections Great vessels Valve disease Eur J Cardiothorac Surg Images in cardio-thoracic surgery Ochronosis of the aorta S. Ghotkar M. Kuduvalli W. Dihmis Cardiothoracic Centre, Thomas Drive, Liverpool, L14 3PE, UK Received 11 June 2002; received in revised form 10 September 2002; accepted 1 October 2002. Corresponding author. Tel.: +44-151-293-2391; fax: +44-151-293-2254 e-mail: vishvsanjay@hotmail.com Key Words: The first 20% of the full text of this article appears below. A 63-year-old lady with alcaptonuria had aortic stenosis and was referred for Full Text of this Article HOME HELP FEEDBACK ... ALL CTSNet JOURNALS

94. ATS -- Sign In Page Green aortic valve alcaptonuria (ochronosis) with severe aortic stenosis.Gregor Zünd, MDa , Andreas C. Schmid, MDa , Paul R. Vogt, MDa , Jürg Grünenfelder http://ats.ctsnetjournals.org/cgi/content/full/67/6/1805

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This item requires a subscription to The Annals of Thoracic Surgery Online. Full Text Green aortic valve: alcaptonuria (ochronosis) with severe aortic stenosis Ann Thorac Surg. This Article Extract Full Text (PDF) Alert me when this article is cited ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager Author home page(s): Paul R. Vogt Marko I. Turina PubMed PubMed Citation Articles by Turina, M. I. To view this item, select one of the options below: Sign In User Name Sign in without cookies. Can't get past this page? Help with Cookies. Password Forgot your user name or password? Purchase Short-Term Access Pay per Article - You may access this article (from the computer you are currently using) for 1 day for US$25.00 Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.

95. OCHRONOSIS (Search FastHealth.com) OCHRONOSIS www.webstersonline-dictionary.org/definition/engl Aortic valve replacement for ochronosis of the aortic valve A patient with generalized ochronosis developed severe cardiovascular symptomsrelated to ochronotic deposits on the aortic valve and in the coronary http://www.fasthealth.com/dictionary/o/ochronosis.php

Dictionary FastHealth Email This! n pl -no*ses ochro*not*ic adj FastNurse Drug Search Hospital Search Find a Physician ... Dead Links FastHealth Corporation (Tuscaloosa, Alabama - Tuscaloosa County)

96. Arch Dermatol -- Abstract: Alkaptonuria With Extensive Ochronosis, April 1979, W Alkaptonuria with extensive ochronosis. HW Wyre Jr. A 59year-old woman withpreviously documented alkaptonuria was examined for extensive ochronosis of http://archderm.ama-assn.org/cgi/content/abstract/115/4/461

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 115 No. 4, April 1979 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Wyre HW Articles that cite this article Contact me when this article is cited Alkaptonuria with extensive ochronosis H. W. Wyre Jr A 59-year-old woman with previously documented alkaptonuria was examined for extensive ochronosis of recent onset. The cause of the extensive skin pigmentations were thought to be secondary to decreased renal clearance of homogentisic acid because of a decline in the patient's renal function. If extensive or rapidly progressive skin pigmentation is noted in a patient with alkaptonuria, then evaluation of the patient's renal status should be

97. Roche Lexikon Medizin, 5. Auflage http://www.gesundheit.de/roche/ro25000/r27348.000.html

Ochron o sis ochronosis Alkaptonurie Verwandte Themen: Alkaptonurie

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