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         Narcolepsy:     more books (100)
  1. Sleep Well: A Natural Remedy Guide for Healthful Sleep! by MsMimee, 2010-06-26
  2. Forever Ahbra by Mary Anderson, 1981-09
  3. Secrets To Sleeping Soundly by Jack Earl, 2009-02-20
  4. Narcoleptic Sunday by Jeremy Haun, 2007-08-15
  5. NarcolepsyMaster of Disguise: Evidence-Based Recommendations for Management by MD Vahid Mohsenin, 2010-05-18
  6. The Shanghai Gesture by Gary Indiana, 2009-04-01
  7. London Revenant by Conrad Williams, 2007-03-21
  8. The Little Sleep: A Novel by Paul Tremblay, 2009-03-03
  9. Dreams, Waking Thoughts, and Incidents by William Beckford, 2010-02-23
  10. Common Causes for Sleep Disturbances and Disorders by LittleWhiteEbook.com, 2010-03-27
  11. How To Win Your War Against Insomnia And Sleep Disorders - The Ultimate Sleeping Guide!(110 Pages)AAA+++
  12. VIVIR DURMIENDO: El sueño excesivo diurno (Spanish Edition) by Rafael J. Salín-Pascual, 2009-11-29
  13. Secrets to Sleeping Soundly
  14. "The Secrets to Sleeping Soundly" by Michelle Tason, 2009-07-04

121. Blackout Records.com
narcolepsy. Release Date 7/26/2005. track listing 1. West Chester Nuclear Winter 2.85 E. Cleaveland 3. A Beatiful Love Song 4. Last Call
http://www.blackoutrecords.com/releasedetail.asp?id=60

122. Mercola.com: "Curing" Insomnia With A Narcolepsy Drug?
Free twiceweekly natural health newsletter of top medical news on subjectsincluding splenda, soy, sucralose, statins, insulin, aspartame, prevention and
http://www.mercola.com/blog/2005/aug/5/curing_insomnia_with_a_narcolepsy_drug
Dr. Joseph Mercola
Author of the
Total Health Program
Enter your e-mail address below to subscribe to my free newsletter:
Previous Issues
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Essential Info Health Blog My Vision My Qualifications #1 Natural Health Website ... More... Health Resources Nutrition Plan Fewer Grains/Sugars More Omega-3 More Water ... E-mail to a Friend "Curing" Insomnia With A Narcolepsy Drug? Last year, I warned you about the skyrocketing sales of Provigil (modafinil), a drug tailored to push Type A people into extreme workaholic behaviors by helping them avoid sleep . Provigil originally marketed to treat narcolepsy may soon be prescribed for shift workers and those suffering from chronic fatigue. A New England Journal of Medicine study found Provigil produced fewer lapses in attention and reduced the number of accidents or near-mishaps by shift workers during their daily commutes. According to researchers, well-rested patients take anywhere from 10-20 minutes to fall asleep. Before taking Provigil, it took shift workers about 2 minutes on average to get there. But after taking the drug, that lag time between increased to about 4 minutes, and some 77 percent of the patients were less likely to be sleepy during their night shift. Not that impressive... And, there were some serious caveats worth taking into consideration:

123. Narcolepsy: Symptoms, Causes, Diagnosis And Treatment
What is narcolepsy? Symptoms, causes, diagnosis, treatment and research discussed.
http://www.helpguide.org/life/narcolepsy_symptom_causes_treatments.htm
Home About Us Contact Site Map Search Helpguide
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Santa Monica
Narcolepsy: Symptoms, Causes, Diagnosis and Treatment
On this page: What is narcolepsy? Signs and symptoms Causes Effects ... Related articles Did You Know?
From, Narcolepsy Basics (National Sleep Foundation)
What is narcolepsy?
Narcolepsy, a chronic neurological disorder, is the second leading cause of excessive daytime sleepiness (after obstructive sleep apnea). People with narcolepsy typically experience:
  • excessive daytime sleepiness, intermittent, uncontrollable episodes of sleep and loss of muscle control (cataplexy) during the day.
If you experience narcolepsy, you may have fallen asleep while working, cooking, or even driving. You are not alone. The National Center on Sleep Disorders Research reports that narcolepsy affects about 1 in 2,000 people and most people experience their first symptoms between the ages of 15 and 30. Evidence suggests that the condition is genetic.
What are the signs and symptoms of narcolepsy?
In addition to excessive daytime sleepiness and sudden episodes of falling asleep, other symptoms typically associated with narcolepsy are:

124. GHB ( Xyrem) And Narcolepsy
that has been under investigation in the management of narcolepsy for abouttwo decades. GHB (Xyrem) and narcolepsy GHB use, abuse and withdrawal
http://www.biopsychiatry.com/ghbnarco.htm
Pharmacokinetics of gammahydroxybutyrate
(GHB) in narcoleptic patients
by
Scharf MB, Lai AA, Branigan B, Stover R, Berkowitz DB
Center For Research In Sleep Disorders,
Cincinnati, Ohio, USA
Sleep 1998 Aug 1; 21(5):507-14
ABSTRACT
S odium gammahydroxybutyrate (GHB) is an endogenous compound that has been under investigation in the management of narcolepsy for about two decades. The data confirm that GHB treatment decreases daytime sleepiness and episodes of cataplexy, sleep paralysis, and hypnagogic hallucinations. The current study evaluated the pharmacokinetics of GHB, given twice in one night to six narcoleptic patients who had been chronically taking GHB nightly on a similar basis. Results confirmed earlier reports and showed nonlinear pharmacokinetics. Maximum concentrations were reached in 40 +/- 6.2 and 35.7 +/- 7 minutes after the first and second dose respectively. Mean AUCinf was 17731.6 +/- 4867 mg/mL/m. Mean GHB T1/2 was 53 +/- 19 minutes. GHB elimination appears to be capacity-limited in some patients when administered at a fixed dose of 3 g twice nightly at a 4-hour interval. GHB
GABA

Opioids

Reward
... A GHB receptor?

125. Stanford Researchers Nab Gene For Narcolepsy In Dogs
Sleep disorder community providing authoritative sleep information and live sleepdisorder support news, chat rooms, message boards, and articles.
http://www.talkaboutsleep.com/sleep-disorders/archives/Narcolepsy_ndogs.htm
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Stanford Researchers Nab Gene For Narcolepsy in Dogs
Washington, DC - August 5, 1999 After a decade-long search, a Stanford-led team has identified a gene that causes the sleep disorder narcolepsy - a breakthrough that brings a cure for this disabling condition within reach, the scientists say. The researchers, led by Emmanuel Mignot, MD, PhD, associate professor of psychiatry at Stanford University School of Medicine, used a technique called positional cloning to pinpoint the gene in dogs, one of the few species besides humans known to develop narcolepsy. Mignot predicts the finding will not only help the roughly 135,000 Americans who suffer from narcolepsy, but in time it will shed light on two of the biggest mysteries in sleep research: how and why we sleep. "This discovery is the exciting culmination of 36 years of research on narcolepsy at Stanford," said William Dement, MD, PhD, director of the Sleep Disorders Research Center at Stanford. "Narcolepsy is the only known neurological disorder that affects the brain and sleep in such a dramatic way," said Mignot, who is director of Stanford's Center for Narcolepsy. It affects both humans and animals and has both genetic and sporadic forms. Usually beginning in adolescence, narcolepsy's symptoms include extreme daytime sleepiness, sleep paralysis a frightening inability to move shortly after awakening or shortly after dozing off as well as vivid auditory or visual hallucinations while asleep or while falling asleep.

126. Narcolepsy / Hypersomnia Info, Treatment Ratings
Which treatments work for narcolepsy / Hypersomnia? RemedyFind is a free, unbiasedsite where you rate the medications, supplements, therapies etc. you’ve
http://remedyfind.com/hc-narcolepsy.asp

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127. - - - - HEALTHOLOGY - - - -
Dr. Joyce Walsleben discusses the causes, diagnosis, and treatments availablefor narcolepsy.
http://www.healthology.com/focus_article.asp?f=sleep_disorders&b=healthology&c=n

128. Narcolepsy Arms
the online journal of words, images, sounds, views.
http://www.narcolepsyarms.com/

vol. 1

words
images sounds
vol. 1

words
images sounds ... views

129. Dr. Koop - Narcolepsy
narcolepsy is a sleep disorder associated with uncontrollable sleepiness andfrequent daytime sleeping.
http://www.drkoop.com/ency/93/000802.html
Home Health Reference Narcolepsy Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library
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Narcolepsy
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Narcolepsy
Definition: Narcolepsy is a sleep disorder associated with uncontrollable sleepiness and frequent daytime sleeping.
Alternative Names: Daytime sleep disorder
Causes, incidence, and risk factors: The exact cause of narcolepsy is unknown. Studies using gene markers have indicated that the disorder may be genetic. A small group of neurons in the brain has been implicated in producing transitions from sleep to wakefulness and vice-versa. People with narcolepsy may have fewer of these neurons or they may have been damaged. The condition may be aggravated by conditions that cause insomnia , such as disruption of work schedules.
Narcolepsy is characterized by episodes of frequent, uncontrollable daytime sleeping, usually preceded by drowsiness . The episodes usually occur after meals, but sudden onset of sleep may occur while working or driving a vehicle, having a conversation, or being in any sedentary or nonstimulating situation. There is a brief period of sleep, and the person awakens feeling refreshed. However, the person may again become uncontrollably sleepy a short time later.

130. Obstructive Sleep Apnea, Narcolepsy, Insomnia, Restless Legs Syndrome, Sleep Hea
Sleep HealthCenters is a healthcare company operating a network of clinics forthe diagnosis and treatment of people with sleep disorders.
http://www.sleephealth.com/
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Sleep Health Centers Better Sleep. Better Health.
It is estimated that at least 40 million Americans suffer from a chronic sleep disorder or intermittent sleep-related problem. Sleep deprivation is an unhealthy, dangerous and costly problem.
Sleep Health Centers is a recognized network of specialized sleep clinics, staffed by experts in the field of sleep medicine. Sleep Health Centers utilizes the most current technologies available to diagnose and treat patients with a wide variety of sleep disorders such as Obstructive Sleep Apnea, Insomnia, Narcolepsy, and Restless Legs Syndrome.
Sleep Health Centers
If you or someone you know may have a sleep disorder, please call Sleep Health Centers toll free at 1-877-SLEEPHC (1-877-753-3742).
Sleep Health Centers Affiliations
Beth Israel Deaconess Medical Center
Faulkner Hospital
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McLean Hospital Sleep Health Centers Toll Free 1-877-SLEEPHC FAX 781-271-0601 info@sleephealth.com For Patients Sleep Health Centers ... Questionnaire • Learn about sleep disorders • Connect with others who have sleep disorders • Read about patients' personal experiences at Sleep Health Centers For Professionals • Research medical literature • Find out about our latest research studies • Learn the referral process and print a referral form Sleep Health Centers In The News...

131. AllRefer Health - Narcolepsy (Daytime Sleep Disorder)
narcolepsy (Daytime Sleep Disorder) information center covers causes, prevention,symptoms, diagnosis, treatment, incidence, risk factors, signs, tests,
http://health.allrefer.com/health/narcolepsy-info.html

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Alternate Names : Daytime Sleep Disorder Definition Narcolepsy is a sleep disorder associated with uncontrollable sleepiness and frequent daytime sleeping.
Sleep Patterns in the Young and Aged The exact cause of narcolepsy is unknown. Studies have indicated that the disorder may be genetic, with studies showing gene markers that may indicate a tendency to develop narcolepsy. A small group of neurons in the brain has been implicated in producing transitions from sleep to wakefulness and vice-versa, and people with narcolepsy may have fewer of these neurons or they may have been damaged. The condition may be aggravated by conditions that cause insomnia , such as disruption of work schedules.

132. Narcolepsy — Fanlight Productions
Follows three individuals whose lives and relationships have been disrupted bythis sleep disorcer. A sleep specialist offers comprehensive scientific
http://www.fanlight.com/catalog/films/323_n.shtml

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Narcolepsy

By Jason Margolis
More than one in 2,000 Americans - perhaps as many as 200,000 people - suffer from narcolepsy, a disorder characterized by the total disruption of the normal sleep pattern. Yet few healthcare providers have been trained to recognize narcolepsy and other sleep disorders, and the majority of sufferers remain undiagnosed. In fact, on average, the disorder is not correctly diagnosed until fourteen years after the person first experiences symptoms. This remarkable film presents the experiences of three individuals whose lives and relationships have been disrupted by narcolepsy. Intertwined with their compelling stories, it offers solid, comprehensive scientific information about this disorder, with the aid of Dr. Emmanuel Mignot, director of the Stanford University Center for Narcolepsy. People with narcolepsy are always sleepy, yet are unable to experience normal, rejuvenating sleep. They may also suffer from vivid hallucinations and temporary muscle paralysis when waking or falling asleep. Most dramatic, narcoleptics are plagued by an effect called cataplexy, where they may collapse without warning. While the popular misconception is that the person has fallen asleep, this is actually an uncontrollable paralysis of their voluntary muscles. The symptoms of narcolepsy typically arise during later adolescence or young adulthood. The condition has no cure, and its precise cause is unknown.

133. NARCOLEPSY
bullet, narcolepsy Med Standford. bullet, Bassetti, C. Aldrich, M. narcolepsy.Neurologic Clinics. 14 545-571. 1996
http://neuroland.com/sleep/narcolepsy.htm
Information for
health care professionals click on brain to return to index page Neuroland Search site Neuro Med Neuro Note Texas Dr ... YSL NARCOLEPSY Complaint of sleepiness or sudden muscle weakness Recurrent daytime naps or lapses into sleep that occur almost daily Overview Male = female Prevalence: about 1 in 4000 in North America and Europe (Hublin et al 1994) Onset: 20 to 40 years old, rarely before age 5 or after age 60. Polysomnography: short sleep latency, short REM sleep latency. Clinical symptoms Excessive sleepiness: Most common initial symptom Sleepiness is similar to those caused by sleep deprivation: most apparent in boring, sedentary situations and is partially relieved by movement. No amount of nighttime or daytime sleep produces full alertness. Cataplexy: Episodic weakness without altered consciousness lasting seconds to minutes. Precipitated by excitement or emotion: may occur several times daily or less than once per month. Laughter is the most common precipitant. Anger, embarrassment, excitement, and other forms of emotion also can induce it.

134. Erowid GHB Vault : Patent #2
GHB Patent for use in treatment of sleeping disorders (narcolepsy) Sleep disordersin mammals, such as insomnia and narcolepsy, are treated by
http://www.erowid.org/chemicals/ghb/ghb_patent2.shtml
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United States Patent
Patent Number: US4738985
Pharmaceutical composition and treatment of narcolepsy
Kluger; Ronald, et. al.
Date of Patent: Apr. 19, 1988
Inventors:
Kluger; Ronald (Don Mills, CA)
Mamelak; Mortimer (Willowdale, CA) Assignee:
The University of Toronto Innovations Foundations (Toronto, CA;
Assignee type: Foreign Company or Corporation) Appl. Number: Filed: Mar. 19, 1986 Related U.S. Application data CROSS REFERENCE TO RELATED APPLICATION This is a Continuation-in-Part of application serial number 06/637,882 filed Aug. 6, 1984 and now U.S. Pat. No. 4,599,355. Int. Cl.-4
U.S. Cl.
Field of Search
References Cited OTHER PUBLICATIONS Chem. Abst. 93-148042f (1980). Primary Examiner - Friedman; Stanley J.
ABSTRACT Sleep disorders in mammals, such as insomnia and narcolepsy, are treated by administering an effective amount of ethyl 4-acetoxybutanoate, or a closely related homolog thereof. The compounds may also be administered to mammals to cause muscle relaxation and as animal anaesthetics. Moreover the compounds appear to inhibit the release of dopamine in the brain, and are hence useful also in treatment of conditions which are associated with abnormalities of dopamine release and dopamine sensitivities, such as Parkinson's disease, schizophrenia and tardive dyskenesia.
10 CLAIMS
FIELD OF THE INVENTION
This invention relates to chemotherapeutic compounds and compositions, useful in the treatment of sleep disorders and other abnormalities in mammals.

135. Brain Foundation - Narcolepsy
narcolepsy is a neurological disorder that causes episodes of unpreventable sleep . narcolepsy occurs when the part of the brain that regulates sleep and
http://www.brainaustralia.org.au/AZ_of_Brain_Disorders/narcolepsy
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Narcolepsy
Description
Narcolepsy is a neurological disorder that causes episodes of unpreventable sleep. These episodes can occur frequently and at inappropriate times, for example while a person is talking, eating or driving. Although sleep episodes can occur at any time, they may be more frequent during periods of inactivity or monotonous, repetitive activity. Narcolepsy occurs when the part of the brain that regulates sleep and wakefulness does not function properly, causing sudden spells of Rapid-Eye-Movement (REM) sleep – the dreaming state of sleep. These "sleep attacks” last from a few seconds to 30 minutes, regardless of the amount or quality of night time sleep. These attacks result in episodes of sleep at work and social events, while eating, talking, driving, or on other similarly inappropriate occasions. Symptoms generally begin between the ages of 15 and 30. The four classic symptoms of the disorder (although not all sufferers will have all four) are:
  • Excessive daytime sleepiness.

136. Mental Help Net - 100 - Information - Symptoms - Symptoms - Narcolepsy
Symptoms narcolepsy Mental Help Net Staff. narcolepsy Symptoms. Irresistibleattacks of refreshing sleep that occur daily over at least 3 months.
http://mentalhelp.net/poc/view_doc.php?type=doc&id=561&cn=100

137. Welcome
NODSS Logo narcolepsy and. Overwhelming. Daytime. Sleep To provide supportfor people with narcolepsy and any other sleep disorder, for their families
http://www.nodss.org.au/
NODSS N arcolepsy and O verwhelming D aytime S leep S ociety of Australia ABN 74 098 031 595 Home
Excessive Daytime Sleepiness in General

What's New?

Frequently Asked Question's

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What is NODSS?
NODSS was founded by psychologist Dr Dorothy Bruck in 1986, along with a small group of volunteers. NODSS became an incorporated body in 1988, and was also classified as a public benevolent institution under the Tax Act (Australia). It operates as a national body. The aims of NODSS are: To provide support for people with narcolepsy and any other sleep disorder, for their families and friends, and for doctors, health professionals and students. To encourage research and aid in facilitation of same. To gather information and to provide a means of access to this for interested persons. Services provided by NODSS are: 24 hour phone counseling and information service. (see email us or see contacts page for phone numbers and addresses) Bimonthly newsletter "The Reveille" Bimonthly meetings in Melbourne with guest speakers Information package available on request Library of articles and books ( enquiries welcome Questions or problems regarding this web site should be directed to the web maker
Last modified: Tuesday January 29, 2002.

138. Antidepressant Drugs For Narcolepsy (Cochrane Review)
Abstract of a systematic review of the effects of health care prepared by theCochrane Collaboration.
http://www.update-software.com/Abstracts/AB003724.htm
From The Cochrane Library, Issue 3, 2005
Antidepressant drugs for narcolepsy (Cochrane Review)
Vignatelli L, D'Alessandro R, Candelise L ABSTRACT What's new in this issue Search abstracts Browse alphabetical list of titles Browse by Review Group A substantive amendment to this systematic review was last made on 01 May 2005. Cochrane reviews are regularly checked and updated if necessary. Background: Narcolepsy is a disorder of the central nervous system, the main symptoms of which are excessive daytime sleepiness (EDS) and cataplexy (an abrupt and reversible decrease in or loss of muscle tone, affecting the limbs and/or trunk, elicited by emotional stimuli). Narcolepsy has an adverse impact on people's quality of life. Together with stimulant drugs (used to control EDS), antidepressants are usually recommended to counteract cataplexy. In addition, some antidepressants are also reported to improve EDS. Objectives: To evaluate the effects of antidepressant drugs on EDS, cataplexy, quality of life, and their side effects in people with narcolepsy. Search strategy: We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 3, 2003), MEDLINE (1966 to 2003), EMBASE (1980 to 2003), PsycINFO (1872 to 2003), and CINAHL (1981 to 2003). Bibliographies of identified articles were reviewed to find additional references. Unpublished randomised trials were searched for by consulting governmental and non-governmental clinical trial registers, disease-specific websites, investigators and experts in the field, pharmaceutical companies/manufacturers.

139. Narcolepsy Institute, Montefiore Medical Center, Bronx NY

http://www.narcolepsyinstitute.org/

140. Neurology -- Collected Resources : Narcolepsy
CSF hypocretin1 (orexin-A) levels in childhood narcolepsy and neurologic A monozygotic twin pair discordant for narcolepsy and CSF hypocretin-1
http://www.neurology.org/cgi/collection/narcolepsy
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Citations 1-10 of 27 total displayed. Most recent content (12 Jul 2005):
BRIEF COMMUNICATIONS
Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury
C. R. Baumann, R. Stocker, H. -G. Imhof, O. Trentz, M. Hersberger, E. Mignot, and C. L. Bassetti
Neurology 2005; 65: 147-149. [Abstract] [Full text] [PDF]
Past content (since Jan 2001):
CLINICAL/SCIENTIFIC NOTES
CSF hypocretin-1 (orexin-A) levels in childhood narcolepsy and neurologic disorders
J. Arii, T. Kanbayashi, Y. Tanabe, Y. Sawaishi, S. Kimura, A. Watanabe, K. Mishima, Y. Hishikawa, T. Shimizu, and S. Nishino
Neurology 2004; 63: 2440-a-2442-a. [Full text] [PDF]
BRIEF COMMUNICATIONS
In vivo evidence of neuronal loss in the hypothalamus of narcoleptic patients
R. Lodi, C. Tonon, L. Vignatelli, S. Iotti, P. Montagna, B. Barbiroli, and G. Plazzi
Neurology 2004; 63: 1513-1515. [Abstract] [Full text] [PDF]
EXPEDITED BRIEF COMMUNICATION
A polymorphism of the hypocretin receptor 2 gene is associated with cluster headache

Neurology 2004; 63: 1286-1288.

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