41. Narcolepsy And Hypocretin: Information And Background This site gives clinical, genetic and HLA information about this disorder. http://www.geocities.com/mhungs

Narcolepsy Epidemiology Symptoms Diagnosis Treatment ... Genetics and HLA Part Links

42. Modafinil ( Provigil ) Information about this moodbrightening and memory-enhancing psychostimulant which enhances wakefulness and vigilance. Discusses mode of action and uses in treating narcolepsy, as well as experimental uses. http://www.modafinil.com/

From THE GOOD DRUG GUIDE modafinil Provigil ', 'Alertec', 'Vigicer', 'Modalert', etc) is a memory-improving and mood-brightening psychostimulant. It enhances wakefulness and vigilance , but its pharmacological profile is notably different from the amphetamines methylphenidate Ritalin ) or cocaine . Modafinil is less likely to cause jitteriness, anxiety, or excess locomotor activity - or lead to a hypersomnolent 'rebound effect' - than traditional stimulants . Subjectively, it feels smoother and cleaner than the amphetamines too. The normal elimination half-life of modafinil in humans is between 12 - 15 hours . So it's worth fine-tuning one's dosage schedule accordingly. Current research suggests modafinil, like its older and better-tested analogue adrafinil , is a safe, effective and well-tolerated agent. It is long-acting and doesn't tend to cause peripheral sympathetic stimulation. Yet its CNS action isn't fully understood. Modafinil induces wakefulness in part by its action in the anterior hypothalamus . Its dopamine -releasing action in the nucleus accumbens is weak and dose-dependent; the likelihood of a euphoric response ('abuse potential'), dose-escalation and tolerance is thus apparently small. Modafinil has central

43. EMedicine - Narcolepsy : Article By Matthew J Baker, MD narcolepsy narcolepsy is characterized by the classic tetrad of excessivedaytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis. http://www.emedicine.com/NEURO/topic522.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Neurology Sleep Related Diseases Narcolepsy Last Updated: October 4, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, sleep paralysis, hypersomnolence, sleep disorder AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Matthew J Baker, MD , Consulting Staff, Collier Neurologic Specialists, Naples Community Hospital Coauthor(s): Selim R Benbadis, MD , Director of Comprehensive Epilepsy Program, Professor, Departments of Neurology and Neurosurgery, University of South Florida, Tampa General Hospital Matthew J Baker, MD, is a member of the following medical societies: American Academy of Neurology Editor(s): Carmel Armon, MD, MHS , Professor of Neurology, Tufts University School of Medicine, Chief, Division of Neurology, Baystate Medical Center, Springfield, Massachusetts;

44. NHLBI, Narcolepsy Basic information on narcolepsy from National Institutes of Health National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/nhlbi/sleep/gp/narcolep.htm

45. Adamcadre.ac: Interactive Fiction narcolepsy. Game or story? Story; almost no gamelike elements. Download narcolepsyfor Windows. This package includes the Blorb file for narcolepsy, http://adamcadre.ac/if.html

To most people who've heard of it, the entry for "interactive fiction" in their mental dictionaries goes something like this: " Interactive fiction , noun. A fancy name for text adventures, a type of computer game popular in the early 1980s despite having no graphics. Usually involved wandering around in caves solving complicated puzzles, and became completely obsolete around the time Reagan left office, as graphics became less crappy." The problem with this definition is that the medium introduction IF archive . And if you'd like a preview of this IF stuff before you download, you can play a few moves of my shortest and most basic offering, , right off your web browser. (Whereas if you'd prefer to learn about Glulx Inform, which I've been using to create these things, check out Gull Game or story? Story; almost no gamelike elements. Easy or difficult? Easy; if stuck, just keep exploring. Good for newcomers? I hope so! First released in December 2003. Download Narcolepsy for Windows . This package includes the Blorb file for Narcolepsy, the Glulx interpreter for Windows along with a file needed to make that interpreter work, a configuration file to cover up the gears and pulleys, and the release notes (a must-read before playing). Just download and open the package and double-click on the "play-Narcolepsy" file to begin. (488K) Download the Blorb file alone, if you're on another platform. (This does work on the Mac, though there are some glitches with the way certain messages are printed; it shouldn't interfere with gameplay, though.) (278K)

46. Scientific American: Feature Article: Narcolepsy: January 2000 Image Dusan Petricic, after a cartoon from the American narcolepsy Association.OVERWHELMING SLEEPINESS is a symptom that best characterizes narcolepsy. http://www.npi.ucla.edu/sleepresearch/sciam.htm

Narcolepsy Although people with the disorder do not fall face-first into their soup as in the movies, narcolepsy is still a mysterious disease. But science has new leads by Jerome M. Siegel SUBTOPICS: Sleep and Narcolepsy Narcoleptic Dogs An Autoimmune Disease? FURTHER INFORMATION We have found the first evidence of neuronal degeneration in narcolepsy. After hearing the punch line of the joke, the teenager falls to the floor, almost as if actually punched. She remains there, completely unable to move. She hears her parents reassure her friends that they need not worry about her because she will be all right in a few minutes. She is embarrassed and frustrated as the episode continues, and her friends begin to leave. They bid her goodbye, but she is unable to respond. Although she cannot talk or move, she is otherwise in a state of high alertness, feeling, hearing and remembering everything that is going on around her. The episode lasts for five minutes, longer than her typical cataplexieswhich often last only secondsbut shorter than her longest episode, which lasted 25 minutes. Then it ends, almost as abruptly as it began. She gets up from the floor, and her everyday life resumes. Cataplexy, the loss of skeletal muscle tone without loss of consciousness, is one of the defining symptoms of a puzzling neurological disorder called narcolepsy. The cataplectic attacks of narcolepsy are frequently prompted by laughter; other times, embarrassment, social interactions with strangers, sudden anger, athletic exertion or sexual intercourse may trigger an episode.

47. Modafinil - Drugs & Vitamins - Drug Library - DrugDigest Information from DrugDigest on dosage, usage, side effects, and interactions of this medication used to treat excessive daytime sleepiness associated with narcolepsy. http://www.drugdigest.org/DD/DVH/Uses/0,3915,550410|Modafinil,00.html

Drug Library Check Interactions Compare Drugs Interactive Tools Supplements Pill Images Using Medicine Drug Comparisons Side Effect Comparisons Health Conditions Treatment Options Care Paths Health Risk Assessments Medication Card Medication Checklist showLayer('mainNav'); Search Conditions Modafinil Active Ingredients: Modafinil Representative Names: Provigil Available Product Images: What are modafinil tablets? What should my health care professional know before I take modafinil? How should I take this medicine? What if I miss a dose? ... Where can I keep my medicine? What are modafinil tablets? (Back to top) What should my health care professional know before I take modafinil? (Back to top) They need to know if you have any of these conditions: How should I take this medicine? (Back to top) Take modafinil tablets by mouth. Take your daily dose in the morning hours to get the best effects during the day; taking the medication in the afternoon or evening might interfere with your night-time sleep. Follow the directions on the prescription label regarding how to take this medicine. Swallow the tablets with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Remember: Your prescription for modafinil is only for you. You should never share or give your modafinil prescription to anyone else.

48. Recent Developments In Narcolepsy Research Our group at UCLA identified abnormalities in human brains that pinpoint thecause of most human narcolepsy. http://www.npi.ucla.edu/sleepresearch/xnarcnet.htm

Recent Developments in Narcolepsy Research, An Explanation for Patients and the General Public Jerome Siegel, UCLA, VA GLAHS Reprinted from the Narcolepsy Network Newsletter Winter, 2000 The cause of the death of the hypocretin cells is not entirely clear, but there are two possibilities. One is that a specific "poison" produced by the body or absorbed through the environment kills these cells. Parkinson's disease, another neurological disease caused by the loss of specific brain cells, can be triggered by ingested toxins, for instance. The second and more likely possibility is that the hypocretin cells are killed by the immune system, which confuses these cells with an infectious agent such as a virus. Other cells near where the hypocretin cells should have been appear to be normal; this indicates that whatever the cause of the cell loss, the hypocretin cells are targeted very specifically. What does finding the cause of narcolepsy mean for people with narcolepsy? This discovery ends the 120-year search for the cause of this debilitating disease. It also has important implications for people with narcolepsy: 1. We have clearly shown that narcolepsy is a neurological disease not a psychiatric one. The problem in not "in your mind," but rather is caused by damage to your brain, specifically to the hypothalamus. Many persons with narcolepsy have not only had to suffer from the disease but also from family members, friends and even physicians, who thought of narcolepsy as a motivational problem. Only the ignorant will now consider narcolepsy a psychological problem.

49. The Page Cannot Be Found Information on the difficulties associated with diagnosis and treatment. http://users.pullman.com/beaumont/Narcolepsy.htm

The page cannot be found The page you are looking for might have been removed, had its name changed, or is temporarily unavailable. Please try the following: If you typed the page address in the Address bar, make sure that it is spelled correctly. Open the home page, and then look for links to the information you want. Click the Back button to try another link. HTTP 404 - File not found Internet Information Services Technical Information (for support personnel) More information: Microsoft Support

50. Sleep Apnea, Narcolepsy, Hypersomnia And Other Sleep Disorders (Columbus) Sleep medicine resources for detection and control of sleep apnea, narcolepsy, hypersomnia, insomnia and sleep disorders. http://www.netexp.net/~flamenco/sleepresources.html

51. Narcolepsy narcolepsy is a chronic, or longlasting, sleep disorder with no known cause . When a person has narcolepsy, messages about when to sleep and when to be http://www.4woman.gov/faq/narcolep.htm

Skip navigation Narcolepsy Printer-friendly version PDF file, 179 Kb] What is narcolepsy? What are the symptoms of narcolepsy? Should I worry about getting narcolepsy? How is narcolepsy diagnosed? ... What can I do to cope with narcolepsy? What is narcolepsy? Narcolepsy is a chronic , or long-lasting, sleep disorder with no known cause. It affects the body's central nervous system, which is made up of nerves that carry messages from the brain to other parts of the body. When a person has narcolepsy, messages about when to sleep and when to be awake can get mixed up. This can cause a person to fall asleep when they do not want to, and often without any warning like feeling drowsy. The desire to sleep can be overwhelming and hard to resist, and can happen to a person several times during the day. Night sleep may also be poor, broken up by waking up often during the night. If not controlled with medication, narcolepsy can cause serious problems in a person's personal, social, and work life. It can also limit a person's activities, such as driving a car, work, and exercising. Studies indicate that narcolepsy may run in families. What are the symptoms of narcolepsy?

52. The Sleep Site. Sleep Apnea, Snoring, Narcolepsy, Insomnia And Other Causes Of D Snoring, sleepiness, sleep apnea, insomnia, narcolepsy and other sleep disordersare serious health problems and receive treatment at The Columbus Community http://www.thesleepsite.com/

Sleep Apnea, Snoring, Narcolepsy, Insomnia and Other Sleep Disorders. THE SLEEP SITE. HOW ARE SLEEP PROBLEMS AFFECTING YOU WHAT IS THE PRESENT IMPACT OF SLEEP DISORDERS ON YOUR HEALTH? ON YOUR JOB? ON YOUR FAMILY? ON YOUR BUSINESS? HOW CAN YOU TELL WHETHER YOU AND THOSE CLOSE TO YOU SUFFER FROM SLEEP DISORDERS?... AND WHAT CAN YOU DO ABOUT THEM THE SLEEP SITE: Bringing the mysteries of the night to the light of day. WHAT SHOULD YOU KNOW ABOUT SLEEP AND ITS DISORDERS? SLEEPINESS CAN INDICATE THE PRESENCE OF SERIOUS ILLNESSES Sleepiness whether due to sleep apnea, heavy snoring, idiopathic hypersomnia, narcolepsy, insomnia or other sleep-related disorders -threatens the health and economic security of millions of Americans. -For example, sleep apnea has been associated with heart attacks, heart failure, stroke, hypertension, abnormal heart rhythms, convulsions, memory problems, slowed thinking, irritability, mood swings, depression and high speed highway crashes Sleep apnea has been diagnosed in up to 10% of men over age 40 Loud snoring often indicates sleep apnea and related problems: with increased risk of both severe sleepiness and major health problems.

53. Department Of Sleep Medicine, LUHD Sleep apnoea/hypopnoea syndrome (SAHS), narcolepsy, and periodic limb movement syndrome (PLMS). Royal Infirmary of Edinburgh. http://www.show.scot.nhs.uk/sleep/index.htm

Your browser does not support script Last Updated: 24 May, 2005 A clinical, research and teaching centre offering: Services for patients with sleep disorders Research and education in sleep medicine The Royal Infirmary of Edinburgh 51 Little France Crescent Old Dalkeith Road Edinburgh Outpatient Appointments - 0131 242 3870 Nursing staff - 0131 242 3875/6 Research staff - 0131 242 3879/82/81 Fax - 0131 242 3878 Please telephone between 9 - 12 and 1 - 5pm.

54. Neuroscience For Kids - Narcolepsy These are examples of what people with narcolepsy experience. People with narcolepsyhave trouble staying awake. Narcoleptic often feel drowsy and fall http://faculty.washington.edu/chudler/narco.html

Narcolepsy Narcolepsy Imagine listening to a funny joke, then in the middle of laughing, your legs suddenly buckle and you are unable to move for the next several minutes. Maybe you are in class, but you are incredibly drowsy and finally just can't stay awake even though you had plenty of sleep the night before. These are examples of what people with narcolepsy experience. People with narcolepsy have trouble staying awake. Narcoleptic often feel drowsy and fall asleep, even in the middle of the day, sometime in the middle of activities that produce strong emotions. It is thought that narcolepsy occurs when rapid eye movement (REM) sleep occurs while people are awake. Although the cause of narcolepsy is unknown, it does occasionally run in families. If one person in a family has the disorder, another relative may be susceptible to developing it if certain environmental triggers occur. Symptoms Excessive daytime sleepiness: people may fall asleep when they are doing a boring task or when they are working alone. These sleep attacks may become more frequent and occur at inappropriate and dangerous times such as when they are driving a car. Cataplexy: sudden loss of muscle tone. Loss of muscle tone in the legs may cause a person to fall down. In people with normal sleep/wake functioning, loss of muscle tone is associated exclusively with REM sleep.

55. Domain Name Renewal And Web Hosting From Network Solutions Located in uptown Toronto, Silent Partners Sleep Laboratory is a seven bed laboratory with state of the art equipment. We diagnose and treat many different kinds of sleep disorders including snoring, sleep apnea, insomnia, periodic leg movement and restless leg syndromes, narcolepsy and parasomnias. http://www.silentpartners.org

silentpartners.org Renew Now If you are the current registrant for this domain name* and wish to continue the registration on the domain, you must immediately renew the domain to ensure the name is not deleted from your account. Backorder If you are not the current registrant and are interested in getting this domain name, you can submit a backorder through our trusted partner, SnapNames. There is no upfront fee or risk to place a backorder. Learn More Search For Another Domain Enter a domain name: www. .com .net .org .info .biz .us * Once a domain name has been renewed, it may take up to 48 hours to be reactivated. Web hosting packages from Network Solutions POPULAR CATEGORIES Travel Car Rental Hotels Airline ... Service Agreement , and Legal Notice

56. Howstuffworks "What Is Narcolepsy?" What is narcolepsy? In the movies, people who are. http://science.howstuffworks.com/question676.htm

TCDA("cc=oth; dt"); Auto Stuff Science Stuff Health Stuff Entertainment Stuff ... Shop for Stuff Top Subjects Car Engines Lock Picking Nuclear Bombs Tattoos ... Gas Turbine Engines Sponsored By: Subjects Earth Science Engineering Life Science Military ... Browse the Science Library Explore Stuff Lidrock.com Stuffo.com Big List of Articles Get the Newsletter ... ShortStuff What is narcolepsy? What you've seen in the movies is partly true narcoleptics do suddenly fall asleep, but most are treated with medication so that this doesn't happen. Symptoms of Narcolepsy Excessive daytime sleepiness - the overwhelming urge to fall asleep during the day, even after having plenty of sleep the night before Cataplexy - a sudden, usually brief attack of general muscle weakness related to a strong emotional response (fear, anger, laughter) Hypnagogic sleep paralysis - brief episodes of paralysis that occur when falling asleep Hypnopompic sleep paralysis - brief episodes of paralysis that occur when waking up Hypnagogic hallucinations - vivid, usually visual or auditory hallucinations that occur at the onset of sleep (sometime between falling asleep and the actual sleep state) Hypnopompic hallucinations - vivid, usually visual or auditory hallucinations that occur when waking up

57. MSNi - Supporting Sleep Medicine Information and education on various sleep disorders such as sleep apnea, narcolepsy and insomnia. http://www.mwsleep.com/

MSNi will be closing its doors on February 18, 2005. We wish all of our past students success in their current ventures and thank them for their patronage over the years. Please direct all inquiries to Medcare:

58. Narcolepsy - All About Narcolepsy A list of articles about narcolepsy and links to other sites containing narcolepsyinformation. http://sleepdisorders.about.com/od/narcolepsy/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a71' About Sleep Disorders Narcolepsy Sleep Disorders Essentials Sleep Disorders - The Basics Try a Quiz ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Sleep Disorders newsletter! See Online Courses Search Sleep Disorders Narcolepsy - All About Narcolepsy Narcolepsy is a disabling sleep disorder. This page describes methods of diagnosing and treating this disorder, plus articles on cataplexy and research being done on the narcolepsy gene. Alphabetical Recent Narcolepsy - the Basics Narcolepsy is a disorder characterized by excessive daytime sleepiness and periods of muscle weakness called cataplexy. Men and Narcolepsy Narcolepsy is more common in men, according to a recent study done by the Mayo clinic. The study was aimed at determining gender and age specifications of the disorder. Results revealed a higher incidence among men and often began in the late twenties. Invisible Chronic Illness PRESS RELEASE - It's difficult to live with any chronic disease or disability, but when others cannot see that disability and doubt the veracity of what you say about your disability then the difficulty is compounded.

59. NINDS Forwarding Page Information sheet compiled by NINDS, the National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/health_and_medical/disorders/narcolep_doc.htm

NINDS has redesigned its website and the URL for the page you were seeking has changed. The new URL for this page is /disorders/narcolepsy/narcolepsy.htm . Please update your bookmark to this page. You will be automatically taken to this page in 5 seconds, or you can click the link to go there now.

60. Narcolepsy - The Basics narcolepsy is a disorder characterized by excessive daytime sleepiness and periodsof muscle weakness called cataplexy. http://sleepdisorders.about.com/cs/narcolepsy/a/narcobasics.htm

var zLb=14; zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a71' About Sleep Disorders Narcolepsy Narcolepsy - the Basics Sleep Disorders Essentials Sleep Disorders - The Basics Try a Quiz ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Sleep Disorders newsletter! See Online Courses Search Sleep Disorders Stay up to date! Compare Prices Email to a friend ... Print this page Suggested Reading Narcolepsy Narcolepsy: Possible Breakthrough Men and Narcolepsy Recent Discussions melatonin tea puts you to sleep Childhood Insomnia Restless Legs? Elsewhere on the Web Center For Narcolepsy Narcolepsy Network Most Popular Night Sweats - the Basics Night Sweats Sleep Apnea Screening Quiz Sleep Disorders - The Basics ... Sleep Apnea Victim What's Hot Rape Drug For Narcolepsy Sleep Deprivation in College Narcolepsy - the Basics Deprivation and Health ... Night Sweats Knowledge Quiz adunitCM(150,100,'x55') Narcolepsy - the Basics From Florence Cardinal Your Guide to Sleep Disorders FREE Newsletter.

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