1. European Multiple System Atrophy Study Group The European MSA Study Group represents a consortium of neurologists and neuropharmacologists who are dedicated to promote novel therapeutic interventions http://www.emsa-sg.org/

2. Autonomic Movement Disorders Program - Department Of Neurology - Mount Sinai Sch The Autonomic Nervous System Laboratory is the hub of the Department of Neurology s research efforts into autonomic disorders. http://www.mssm.edu/neurology/autodis/disorders/msa/

Multiple System Atrophy Multiple system atrophy is a neurological disorder that begins in adult life and is characterized by parkinsonism, cerebellar ataxia, and autonomic dysfunction in various combinations. Cerebellar ataxia refers to impaired coordination and is caused by degeneration of the cerebellum. Autonomic dysfunction causes orthostatic hypotension (fall in blood pressure upon standing up), bladder and bowel dysfunction, and impotence. Literature on multiple system atrophy Multiple System Atrophy Hypertensive cardiovascular damage in patients with primary autonomic failure Documents above marked are viewable with the free Adobe TM Acrobat TM Reader. If you do not have Acrobat Reader, click on the image below to download it. clinical trials faculty autonomic disorders fellowships ... mssm home Questions? Contact the Web Development Office

3. WE MOVE - Multiple System Atrophy multiple system atrophy (MSA) is a neurodegenerative disease marked by a combination of symptoms affecting movement, blood pressure, and other body http://www.wemove.org/msa/

WE MOVE 204 West 84th Street New York, NY 10024 E-mail: wemove@wemove.org Multiple System Atrophy Multiple System Atrophy Information for Patients and Caregivers (see table of contents below) Multiple System Atrophy Information for Medical Professionals at MDVU Multiple System Atrophy Information for Patients and Caregivers Table of Contents Overview of Multiple System Atrophy Symptoms and Complications of Multiple System Atrophy Treatment of Multiple System Atrophy Multiple System Atrophy Discussion Forum ... Additional Resources WE MOVE makes every effort to present medical information that is up-to-date and accurate. The material provided has undergone rigorous medical review. Information regarding the authors, editors, publisher, and medical reviewers of this material of the WE MOVE Web site is listed below. Medical science is constantly changing. Therefore, the authors, editors, and publisher do not warrant that the information in this text is complete, nor are they responsible for omissions or errors in the text or for the results of the use of this information. This information does not replace consultation with a physician. All medical procedures, drug doses, indications, and contraindications should be discussed with your personal physician. Medical Editor: Richard Robinson, NASW

4. WE MOVE - Multiple System Atrophy Symptoms, complications and treatment of MSA. http://www.wemove.org/msa.html

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5. WE MOVE - Multiple System Atrophy multiple system atrophy (MSA) is a neurodegenerative disease marked by a combination of symptoms affecting movement, blood pressure, and other body http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. WE MOVE Discussion Forum: Multiple System Atrophy Icon 1, multiple system atrophy News April 2005, pbower, 0. April 20, 2005 1105 AM. Icon 10, you want to quit smoking?Try NOSMOQ!!! chary, 0 http://www.wemove.org/ubb/ultimatebb.php?/forum/15.html

7. Page Not Found - Welcome To The National Parkinson Foundation Good Article on MSA by the National Parkinson Foundation. http://www.parkinson.org/atrophy.htm

HOME Page Not Found For Ask the Doctor Ask the Parkinson Dietician click here To view our archive of articles click here For our online publications this section To learn about our events Events Calendar Make a Gift to NPF Doctor, Support Group, or other Resource Surveys and Questionnaires ... Home Page , where you can search the site, or browse for whatever you may be looking for. webmaster@parkinson.org TELL US WHAT YOU THINK ABOUT THIS SITE SITE MAP

8. WE MOVE - Worldwide Education And Awareness For Movement Disorders Education materials on movement disorders. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. MSA multiple system atrophy. In 1960, two researchers, Dr. Milton Shy at the multiple system atrophy is associated with both upper airway and central apnea, http://www.ndrf.org/MSA.htm

NDRF National Dysautonomia Research Foundation PO Box 301, Red Wing, MN 55066-0301 Phone: (651) 267-0525 Fax: (651) 267-0524 Be sure to visit the NDRF Reference Page where you can learn more about the NDRF Patient Handbook, Videos and other reference materials. Multiple System Atrophy In 1960, two researchers, Dr. Milton Shy at the National Institutes of Health, and Dr. Glen Drager at Baylor College of Medicine in Houston, Texas, described a common set of neurological manifestations associated with autonomic failure. Originally called the "Shy-Drager Syndrome" this complex syndrome is currently referred to as "Multiple System Atrophy" or MSA. The American Autonomic Society has defined MSA in the following manner: "MSA is a sporadic, progressive, adult onset disorder characterized by autonomic dysfunction, Parkinsonism, and ataxia (a failure of muscular coordination) in any combination. The features of the disorder include: Parkinsonism Cerebellar or Corticospinal Signs Orthostatic Hypotension, Impotence, Urinary Incontinence or Retention, usually preceding or within two years after the onset of the motor symptoms

10. Shy-Drager Syndrome multiple system atrophy with autonomic failure An article about this disorder giving an explanation, the types, treatment and prognosis. http://healthlink.mcw.edu/article/921961623.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Shy-Drager Syndrome Shy-Drager is often difficult totreat because of the fluctuations in blood pressure. The general treatment course is aimed at controlling symptoms. Anti-Parkinson medication, such as L-dopa, may be helpful but should be used with caution because it can lower blood pressure, causing blackouts. To relieve low blood pressure, dietary increases of salt and fluid may be beneficial. Medications to elevate blood pressure such as corticosteroids may cause side effects and should be carefully monitored by a physician. Alpha-adrenergic medications, metoclopramide, ergotamine derivatives, and indomethacin are useful in many cases. Sleeping in a head-up position at night may reduce headaches and morning dizziness. An artificial feeding tube or breathing tube may be surgically inserted for management of swallowing and breathing difficulties. In rare cases, a pacemaker may be implanted to correct heart irregularities. Shy-Drager usually ends in death 7 to 10 years after the onset of symptoms. Pneumonia is the most common cause of death, although irregularities in heart beat may be responsible for death in some patients.

11. National Institute Of Neurological Disorders And Stroke (NINDS) (multiple system atrophy)A look at this disorder, its treatment, prognosis, research and organizations. http://www.ninds.nih.gov/health_and_medical/disorders/shydrger_doc.htm

Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system Disorder Quick Links Alzheimer's Disease Autism Cerebral Palsy Chronic Pain Epilepsy Headache Multiple Sclerosis Parkinson's Disease Stroke Traumatic Brain Injury Browse All Disorders Search NINDS... (help) Contact Us My Privacy NINDS is part of the National Institutes of Health You are here: Home Page Not Found We have redesigned our website and the page you are looking for has moved. Please visit the NINDS Home Page or, if you're looking for a particular person, please visit the NINDS Organizational Chart National Institute of Neurological Disorders and Stroke Home About NINDS Disorders Funding ... Accessibility

12. Multiple System Atrophy This site is dedicated to my wife Patricia and multiple system atrophy in the hope that it will help others. meta name= http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. EMedicine - Multiple System Atrophy : Article By André Diedrich, MD, PhD multiple system atrophy The concept of multiple system atrophy (MSA) as a unitary diagnosis encompassing several clinical syndromes has a long history http://www.emedicine.com/NEURO/topic671.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Neurology Movement And Neurodegenerative Diseases Multiple System Atrophy Last Updated: January 16, 2002 Rate this Article Email to a Colleague AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: , Research Assistant Professor of Medicine, Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University School of Medicine Coauthor(s): David Robertson, MD , Director of Clinical Research, Professor, Departments of Internal Medicine, Pharmacology, and Neurology, Vanderbilt University American Autonomic Society , and American Heart Association Editor(s): Christopher C Luzzio, MD , Clinical Assistant Professor, Department of Neurology, University of Wisconsin at Madison; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, eMedicine;

14. SDS/MSA Support Group SDS/MSA SUPPORT GROUP REGIONAL MEETING http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Multisystem Atrophy - Neurologychannel Good article on MSA including MSA anatomy. http://neurologychannel.com/msa/

Home Search SiteMap Ask the Dr. ... Medical Store MULTISYSTEM ATROPHY Overview Anatomy of MSA Diagnosis Treatment CONDITIONS ADHD ALS Alzheimer's Disease Autism ... Carpal Tunnel Syndrome Cephalic Disorders Cerebral Palsy Charcot-Marie-Tooth Disease Chronic Pain Dementia Encephalitis Epilepsy ... Guillain-Barre Syndrome Headache Huntington's Disease Hydrocephalus Lou Gehrig's Disease ... Traumatic Brain Injury Vertigo DIAGNOSTIC TESTS CT Scan MRI Scan TREATMENT OPTIONS Botulinum Toxin Therapy Epidural Injection Trigger Point Injection Vagus Nerve Stimulation RESOURCES Clinical Trials Glossary Links MDLocator ... What Is a Neurologist? Videos FOR DOCTORS ONLY Website Services Get Listed in MDLocator CME ABOUT US Healthcommunities.com Testimonials Overview Multisystem atrophy (MSA) is a group of rare, multisystem degenerative diseases that have several clinical features of Parkinson’s and are sometimes referred to as the "Parkinsonism-plus syndromes." When MSA was first identified in 1960 it was named "Shy-Drager Syndrome" after the two physicians who first described its symptoms. Now, Shy-Drager Syndrome is recognized as only one of three manifestations of multisystem atrophy. The other two are

16. MSA multiple system atrophy. In 1960, two researchers, Dr. Milton Shy at the National Institutes of Health, and Dr. Glen Drager at Baylor College of http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Multisystem Atrophy - Neurologychannel Multisystem atrophy (MSA) is a group of rare, multisystem degenerative diseases that have several clinical features of Parkinsons. http://www.neurologychannel.com/msa/

Home Search SiteMap Ask the Dr. ... Medical Store MULTISYSTEM ATROPHY Overview Anatomy of MSA Diagnosis Treatment CONDITIONS ADHD ALS Alzheimer's Disease Autism ... Carpal Tunnel Syndrome Cephalic Disorders Cerebral Palsy Charcot-Marie-Tooth Disease Chronic Pain Dementia Encephalitis Epilepsy ... Guillain-Barre Syndrome Headache Huntington's Disease Hydrocephalus Lou Gehrig's Disease ... Traumatic Brain Injury Vertigo DIAGNOSTIC TESTS CT Scan MRI Scan TREATMENT OPTIONS Botulinum Toxin Therapy Epidural Injection Trigger Point Injection Vagus Nerve Stimulation RESOURCES Clinical Trials Glossary Links MDLocator ... What Is a Neurologist? Videos FOR DOCTORS ONLY Website Services Get Listed in MDLocator CME ABOUT US Healthcommunities.com Testimonials Overview Multisystem atrophy (MSA) is a group of rare, multisystem degenerative diseases that have several clinical features of Parkinson’s and are sometimes referred to as the "Parkinsonism-plus syndromes." When MSA was first identified in 1960 it was named "Shy-Drager Syndrome" after the two physicians who first described its symptoms. Now, Shy-Drager Syndrome is recognized as only one of three manifestations of multisystem atrophy. The other two are

18. Welcome multiple system atrophy (ShyDrager Syndrome) are some of the many disorders that involve a dysfunction of the autonomic nervous system, or http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. The Sarah Matheson Trust For Multiple System Atrophy The Sarah Matheson Trust is the UK charity that offers support and information services to people living with multiple system atrophy and all those that http://www.msaweb.co.uk/

The Sarah Matheson Trust is the UK charity that offers support and information services to people living with Multiple System Atrophy and all those that care for them. It also sponsors research in the cause and treatment of MSA. The site provides information on MSA and outlines the Trust's services and how to access them. sarah matheson trust, msa, multiple system atrophy, multisystem atrophy, autonomic, autonomic dysfunction, cerebellar ataxia, degenerative diseases, glial inclusion bodies, nervous system diseases, neurology, parkinsonism, postural hypotension, shy drager s="na";c="na";j="na";f=""+escape(document.referrer) document.write(""+todaysDate+""); This website provides information for health professionals and people diagnosed with MSA. The information on this site forms part of the range of information leaflets available from the Sarah Matheson Trust. The site is not designed as a diagnostic tool and, as with any medical information, the opinion of your doctor should always be sought. Sarah Matheson Trust, Pickering Unit, St Mary's Hospital, London W2 1NY (phone) 020 7886 1520

20. The Parkinson's Institute Movement Disorders Short article on clinical presentation and treatment. http://www.parkinsonsinstitute.org/movement_disorders/multiple_system.html

Treatment Center PD Dystonia ET ... TS People with Multiple System Atrophy (MSA) can exhibit a wide variety of symptoms, including: postural instability, slowed movements, muscle rigidity, orthostatic hypotension (a fall in blood pressure when standing), and urinary and sexual problems. As the term "multiple system atrophy" implies, MSA can vary in its affect on the nervous system, resulting in a range of symptoms. Thus, MSA is generally separated into three main categories depending on the predominant symptoms. Pharmacological treatment is much the same as Parkinson's disease, although as the disease progresses the benefits of these drugs diminish and often complicate the autonomic dysfunction, particularly orthostatic hypotension (low blood pressure). Orthostatic hypotension is often treated with fludrocortisone (Florinef ), midodrine (ProAmatine), or other drugs that raise blood pressure. Male impotence may be treated with penile implants or drugs. Incontinence may be treated with medications or catheterization. Constipation may improve with increased dietary fiber or laxatives. A speech-language pathologist may be able to offer strategies for improving swallowing and speaking. Use of softer foods may improve the ability to swallow. A gastrostomy tube, which delivers foods directly to the stomach, may be required at some time during the course of the disease. [return to top]

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