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         Multiple Hamartoma Syndrome:     more detail

1. EMedicine - Cowden Disease (Multiple Hamartoma Syndrome) : Article By Charles Mi
Cowden Disease (multiple hamartoma syndrome) Cowden disease (CD), also termedCowden syndrome and multiple hamartoma syndrome, is an autosomal dominant
http://www.emedicine.com/DERM/topic86.htm
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Cowden Disease (Multiple Hamartoma Syndrome)
Last Updated: June 2, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: multiple hamartoma syndrome, Cowden syndrome PTEN (phosphatase and tensin homolog) hamartoma tumor syndrome AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography
Author: Charles Miller, MD , Dermatologist, Department of Dermatology, Southern California Kaiser Permanente Charles Miller, MD, is a member of the following medical societies: American Academy of Dermatology Editor(s): Craig A Elmets, MD , Director of Dermatology, Departments of Dermatology, Professor, Pathology, Environmental Health Sciences, The Kirklin Clinic, University of Alabama at Birmingham; Richard Vinson, MD

2. EMedicine - Cowden Disease (Multiple Hamartoma Syndrome) Article
Cowden Disease (multiple hamartoma syndrome) Cowden disease (CD), also termed Cowden syndrome and multiple hamartoma syndrome, is an autosomal
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

3. EMedicine - Cowden Disease (Multiple Hamartoma Syndrome) : Article Excerpt By: C
Cowden Disease (multiple hamartoma syndrome) Cowden disease (CD), also termedCowden syndrome and multiple hamartoma syndrome, is an autosomal dominant
http://www.emedicine.com/derm/byname/cowden-disease-(multiple-hamartoma-syndrome
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Excerpt from Cowden Disease (Multiple Hamartoma Syndrome)
Synonyms, Key Words, and Related Terms: multiple hamartoma syndrome, Cowden syndrome PTEN (phosphatase and tensin homolog) hamartoma tumor syndrome
Please click here to view the full topic text: Cowden Disease (Multiple Hamartoma Syndrome)
Background: Cowden disease (CD), also termed Cowden syndrome and multiple hamartoma syndrome, is an autosomal dominant condition with variable expression that results most commonly (80%) from a mutation in the PTEN gene on arm 10q, as reported by Liaw et al. A broader category, "PTEN (phosphatase and tensin homolog) hamartoma tumor syndrome," has been suggested as a name to combine multiple phenotypic presentations all due to PTEN genetic diseases. Rare cases of CD are due to a germline mutation in (bone morphogenetic proteins). CD causes hamartomatous neoplasms of the skin and mucosa, GI tract, bones, CNS, eyes, and genitourinary tract. Skin is involved in 90-100% of cases, and the thyroid is involved in 66% of cases. Mucocutaneous features of CD include trichilemmomas, oral mucosal papillomatosis, acral keratoses, and palmoplantar keratoses. CD is associated with the development of several types of malignancy, which is why recognition of individuals with the syndrome is important. In particular, a marked increase is seen in the incidence of breast carcinoma in women and of thyroid carcinoma in both men and women. Reports also exist of several other types of malignancies occurring in patients with CD.

4. EMedicine - Cowden Disease (Multiple Hamartoma Syndrome) Article
Cowden Disease (multiple hamartoma syndrome) Cowden disease (CD), also termed Cowden syndrome and multiple hamartoma syndrome, is an autosomal
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Multiple Hamartoma Syndrome Information Diseases Database
multiple hamartoma syndrome Cowden's syndrome Dysplastic cerebellar gangliocytoma LhermitteDuclos disease, Disease Database Information
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6. Ataxia Dominant
CAG/CTG repeat; 16q23 Mental retardation 19q13 multiple hamartoma syndrome PTEN;
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7. Multiple Hamartoma Syndrome Information Diseases Database
multiple hamartoma syndrome,Cowden s syndrome,Dysplastic cerebellargangliocytoma,LhermitteDuclos disease, Disease Database Information.
http://www.diseasesdatabase.com/ddb31336.htm
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4 synonyms or equivalents were found. Multiple hamartoma syndrome
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Cowden's syndrome
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Dysplastic cerebellar gangliocytoma
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Lhermitte-Duclos disease Multiple hamartoma syndrome: Definition(s) via UMLS Code translations and terms via UMLS Multiple hamartoma syndrome: specific web sites Send Multiple hamartoma syndrome to medical search engines (JavaScript enabled browsers only.) If your browser has no JavaScript you can still use these:
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8. Radiological Findings In Multiple Hamartoma Syndrome (Cowden
Radiological findings in multiple hamartoma syndrome (Cowden disease) a report of three cases H Hauser, B Ody, O Plojoux and P Wettstein
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9. HighWire -- Browse Journals - Multiple Hamartoma Syndrome
Browse Journals publishing on multiple hamartoma syndrome, (return to Topic Listpage Alphabet, , Frequency of articles in multiple hamartoma syndrome
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Year: Vol: Page: Home Adv. Search For Institutions For Publishers ... Sign in or register for access to all HighWire Press customization features Browse Journals publishing on Multiple Hamartoma Syndrome: (return to Topic List page) Multiple Hamartoma Syndrome
Sort by: Alphabet Frequency of articles in Multiple Hamartoma Syndrome Focus of journal on Multiple Hamartoma Syndrome What's this? Journals focusing on Multiple Hamartoma Syndrome (in order by highest focus) American Journal Of Pathology info free ISSUES Journal of the National Cancer Institute ... Hamartoma Multiple Hamartoma Syndrome Home Adv. Search For Institutions For Publishers ... partners/suppliers

10. Arch Dermatol Abstract Multiple Hamartoma Syndrome (Cowden's
multiple hamartoma syndrome (Cowden's disease) D. D. Nuss, J. L. Aeling, D. E. Clemons and W. N. Weber
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11. Multiple Hamartoma Syndrome
Complete online version of The Encyclopaedia of Medical Imaging including textand images from The Encyclopaedia of Medical Imaging s eight book volumes
http://www.amershamhealth.com/medcyclopaedia/medical/Volume IV 1/MULTIPLE HAMART

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our commitment our company Search Medcyclopaedia for: Search marked text (mark text before you click) Browse entry words starting with: A B C D ... amershamhealth.com Multiple hamartoma syndrome, see Cowden disease
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12. Arch Dermatol Abstract Multiple Hamartoma Syndrome (Cowden's
multiple hamartoma syndrome (Cowden's disease) associated with nonHodgkin's lymphoma
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13. Hamartoma, Oesophageal
In patients with multiple hamartoma syndrome they present as numerous very smallsessile lesions causing a small sharply demarcated filling defect on double
http://www.amershamhealth.com/medcyclopaedia/medical/Volume IV 1/HAMARTOMA OESOP

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our commitment our company Search Medcyclopaedia for: Search marked text (mark text before you click) Browse entry words starting with: A B C D ... amershamhealth.com Hamartoma, oesophageal, benign tumour characterized histologically by metaplastic respiratory epithelium and islets of cartilage in a fibrous stroma. They can be solitary or may be multiple as part of the Cowden disease. Radiographically they have a variable appearance on the barium study of the oesophagus. The solitary form presents as a nonspecific intraluminal pedunculated and smoothly lined filling defect. In patients with multiple hamartoma syndrome they present as numerous very small sessile lesions causing a small sharply demarcated filling defect on double contrast barium study of the oesophagus. Also, see Cowden disease
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14. Webkatalog
Websites 1. Cowden Syndrome A CHORUS notecard document about this syndrome. http//chorus.rad.mcw.edu/doc/00100.htm. ..
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15. Hamartoma Syndrome, Multiple
Hamartoma Syndrome, Multiple Medical.WebEnds.com. Cowden s Disease; MultipleHamartoma Syndrome; Cowden Disease; Cowdens Disease; Disease, Cowden;
http://medical.webends.com/kw/Hamartoma Syndrome, Multiple
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Hamartoma Syndrome, Multiple
A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Papules of the face and oral mucosa are the most characteristic lesion. Other changes occur in the skin , in the thyroid, the breast , the gastrointestinal system, and the nervous system
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16. HighWire Browse Journals - Multiple Hamartoma Syndrome
Browse Journals publishing on multiple hamartoma syndrome (return to Topic List page) multiple hamartoma syndrome Sort by
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17. Arch Dermatol -- Abstract: Multiple Hamartoma Syndrome (Cowden's Disease) Associ
multiple hamartoma syndrome (Cowden s disease) associated with nonHodgkin s A 70-year-old woman with the multiple hamartoma syndrome is described.
http://archderm.ama-assn.org/cgi/content/abstract/122/5/572
Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress
Vol. 122 No. 5, May 1986 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Elston DM Graham GF Contact me when this article is cited
Multiple hamartoma syndrome (Cowden's disease) associated with non-Hodgkin's lymphoma
D. M. Elston, W. D. James, O. G. Rodman and G. F. Graham
A 70-year-old woman with the multiple hamartoma syndrome is described. Diagnosis was based on the clinical presentation and histopathologic examination of cutaneous trichilemmomas. The case is reported to document the association of Cowden's disease with non-Hodgkin's lymphoma. This is the first known report of the occurrence of trichilemmomas in the sacral area. The literature concerning the association of the multiple hamartoma

18. HONselect - Hamartoma Syndrome, Multiple
Cowden's Disease - multiple hamartoma syndrome - Cowden Disease - Cowdens Disease - Disease, Cowden - Disease, Cowden's. Fran ais
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19. Arch Dermatol -- Abstract: Multiple Hamartoma Syndrome (Cowden's Disease), May 1
The four male patients with multiple hamartoma syndrome (Cowden s disease) inthis report, have most of the previously reported findings associated with
http://archderm.ama-assn.org/cgi/content/abstract/114/5/743
Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress
Vol. 114 No. 5, May 1978 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Nuss DD Weber WN Articles that cite this article Contact me when this article is cited
Multiple hamartoma syndrome (Cowden's disease)
D. D. Nuss, J. L. Aeling, D. E. Clemons and W. N. Weber
The four male patients with multiple hamartoma syndrome (Cowden's disease) in this report, have most of the previously reported findings associated with this syndrome and several important unreported findings that include multiple cutaneous trichilemmomas, cafe-au-lait spots, cutaneous squamous cell carcinoma, pathologic fracture, craniomegaly, probable malignant lung tumor, retinal glioma, drusens of the optic disk and retina, pseudotumor

20. Entrez PubMed
multiple hamartoma syndrome (Cowden s disease). Weary PE, Gorlin RJ, Gentry WCJr, Comer JE, Greer KE. MeSH Terms. Abnormalities, Multiple/genetics*
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4

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