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         Moersch-woltmann Syndrome:     more detail

1. Stiff-man Syndrome (a.k.a. Moersch-Woltmann Syndrome)
Stiffman Syndrome (aka moersch-woltmann syndrome) -Stiff-man syndrome, alsocalled moersch-woltmann syndrome, is a rare, severe autoimmune neurologic
http://www.medical-library.net/sites/_stiff-man_syndrome.html
Stiff-man Syndrome
(a.k.a. Moersch-Woltmann Syndrome)
by Ron Kennedy, M.D., Santa Rosa, California
Stiff-man syndrome, also called Moersch-Woltmann syndrome, is a rare, severe autoimmune neurologic disease involving the central nervous system. Autoimmune disorders are caused when the body's immune system, which is meant to defend the body against bacteria, viruses, and any other foreign product, malfunctions and produces antibodies against healthy tissue, cells and organs. The disease is characterized by a progressive rigidity or stiffness of the muscles caused by a diffuse hypertonia (excess muscular tension or pressure) involving the voluntary muscles of the neck, shoulders, trunk, arms and legs. Painful muscle spasms may also be present. Unlike many autoimmune diseases which have a higher incidence in women, stiff-man syndrome is found more frequently in men. Approximately 70 percent of those afflicted are men. Oddly enough, women can have the stiff-man syndrome.
While the exact cause of stiff-man syndrome is not clear, autoimmunity is thought to be a factor. The frequent occurrence of insulin-dependent diabetes mellitus IDDM ), (also referred to as

2. Stiff-man Syndrome (a.k.a. Moersch-Woltmann Syndrome)
Stiffman Syndrome (a.k.a. moersch-woltmann syndrome) -Stiff-man syndrome, also called moersch-woltmann syndrome, is a rare, severe autoimmune
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

3. Stiff Person Syndrome
moerschwoltmann syndrome; Muscular Rigidity - Progressive Spasm; SMS; Stiff ManSyndrome. Disorder Subdivisions. None. General Discussion
http://my.webmd.com/hw/health_guide_atoz/nord326.asp
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Who We Are About WebMD Site Map You are in Medical Library Our Content Sources Ask A Question Clinical Trials Health Guide A-Z Health Topics Symptoms Medical Tests Medications ... For a Complete Report Stiff Person Syndrome Important It is possible that the main title of the report Stiff Person Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms
  • Moersch-Woltmann Syndrome Muscular Rigidity - Progressive Spasm SMS Stiff Man Syndrome
Disorder Subdivisions
  • None
General Discussion Stiff-person syndrome is an extremely rare neurological disorder characterized by progressive muscle stiffness (rigidity) and spasms. It usually begins in young adults, first involving muscles of the trunk and progressing to affect muscles of the legs. This syndrome may begin as recurring (intermittent) episodes of stiffness and spasms, often precipitated by surprise or minor physical contact. Those affected have a characteristic stiff-legged way of walking (gait) and increase in the curvature of the spine (lordotic posture). The exact cause of stiff person syndrome is not known. Resources American Autoimmune Related Diseases Association, Inc.

4. Stiff Person Syndrome Support Stiff-man Syndrome
Stiff Person Syndrome Support Stiffman Syndrome, moersch-woltmann syndrome
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Index
MarinescoSjogren Syndrome-Hypergonadotrophic Hypogonadism Marinesco-SjogrenSyndrome- Moebius Syndrome moersch-woltmann syndrome Mohr Syndrome
http://my.webmd.com/hw/index/index-topics-M.asp
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Medical Info
Check Symptoms

Medical Library

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... Women, Men, Lifestyle
Who We Are About WebMD Site Map You are in Medical Library Our Content Sources Ask A Question Clinical Trials Health Guide A-Z Health Topics Symptoms Medical Tests Medications ... Support Organizations Search the Help Health Topics Click a letter to see a list of topics beginning with that letter A B C D ... MY MA MAA Machado Disease Machado-Joseph Disease Macrocephaly, multiple lipomas, and hemangiomata ... back to top MC MCAD Deficiency McArdle Disease McCune Albright Syndrome MCD ... back to top MD MdDS back to top ME ME Measles (Rubeola) Meckel Syndrome Meckel-Gruber Syndrome ... back to top Ménière's Disease back to top ME Menieres Menieres Disease Meningeal Capillary Angiomatosis Meningeal Fibroblastoma ... back to top MF back to top MG MG back to top MH MH MHA back to top MI Michail-Matsoukas-Theodorou-Rubinstein-Taybi Syndrome Microangiopathic Hemolytic Anemia Microangiopathy of the Regina, Cochlea, and Brain Microangiopathy of the Retina, Cochlea, and Brain ... back to top MJ MJD back to top MK MKS back to top ML ML Disorder III ML Disorder IV ML Disorder, Type II

6. Moersch-Woltmann Syndrome
moerschwoltmann syndrome moersch-woltmann syndrome
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. EMedicine - Stiff Person Syndrome : Article Excerpt By: Nancy Rodgers-Neame, MD
The eponym for this syndrome, moerschwoltmann syndrome, is one of the fewinstances in which the eponym may be the most inclusive and at the same time most
http://www.emedicine.com/neuro/byname/stiff-person-syndrome.htm
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Excerpt from Stiff Person Syndrome
Synonyms, Key Words, and Related Terms: SPS, stiff man syndrome, SMS, stiff baby syndrome, SBS, hyperekplexia, Moersch-Woltmann syndrome, stiff woman syndrome, stiff limb syndrome
Please click here to view the full topic text: Stiff Person Syndrome
Background: Stiff person syndrome is rather unique among neurologic diagnoses because of its lack of significant similarity to any other neurologic diseases. Although rare, once observed it is quite unforgettable. Possibly the closest related disease is tetanus because both conditions affect peripheral inhibition via central mechanisms and both conditions inhibit central gamma-aminobutyric acid (GABA) systems. In 1956, Moersch and Woltmann, who also coined the term stiff man syndrome, first clearly described stiff person syndrome as a neurologic clinical entity at the Mayo Clinic. The eponym for this syndrome, Moersch-Woltmann syndrome, is one of the few instances in which the eponym may be the most inclusive and at the same time most appropriately limiting name for the disease. Stiff person seems to exclude babies, and stiff man is inappropriate for children and women; perhaps stiff individual most perfectly describes the affected patient. Some confusion and controversy has also ensued as a result of cases that include other neurologic findings, such as encephalomyelitis or cerebellar deficits, in addition to the classic clinical syndrome. To further confuse matters, the most common pathologic correlate, anti–glutamic acid decarboxylase (GAD) antibodies, have been associated with a wide range of human disease, including diabetes mellitus and seizures.

8. Webkatalog
Reizdarm prue13 Frauen und Analverkehr frank.f Sie sind hier Startseite Fit Gesund Webkatalog. StiffPerson Syndrome Websites
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. Stiff Person Syndrome - Quest Diagnostics Patient Health Library
Synonyms. moerschwoltmann syndrome; Muscular Rigidity - Progressive Spasm; SMS;Stiff Man Syndrome. Disorder Subdivisions. None. General Discussion
http://www.questdiagnostics.com/kbase/nord/nord326.htm
var hwPrint=1;var hwDocHWID="nord326";var hwDocTitle="Stiff Person Syndrome";var hwRank="1";var hwSectionHWID="nord326-Header";var hwSource="en-usQ2_05";var hwDocType="Nord";
National Organization for Rare Disorders, Inc.
Stiff Person Syndrome
Important
It is possible that the main title of the report Stiff Person Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
  • Moersch-Woltmann Syndrome Muscular Rigidity - Progressive Spasm SMS Stiff Man Syndrome
Disorder Subdivisions
  • None
General Discussion
Stiff-person syndrome is an extremely rare neurological disorder characterized by progressive muscle stiffness (rigidity) and spasms. It usually begins in young adults, first involving muscles of the trunk and progressing to affect muscles of the legs. This syndrome may begin as recurring (intermittent) episodes of stiffness and spasms, often precipitated by surprise or minor physical contact. Those affected have a characteristic stiff-legged way of walking (gait) and increase in the curvature of the spine (lordotic posture). The exact cause of stiff person syndrome is not known.
Resources
American Autoimmune Related Diseases Association, Inc.

10. Stiff Person Syndrome Moersch-Woltmann Syndrome Muscular Rigidity
Stiff Person syndrome moerschwoltmann syndrome Muscular Rigidity - Progressive Spasm SMS Stiff Man Syndrome Stiff Person syndrome Moersch-Woltmann
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. Health Topics - Quest Diagnostics Patient Health Library
MichailMatsoukas-Theodorou-Rubinstein-Taybi Syndrome Microangiopathic HemolyticAnemia Moebius Syndrome moersch-woltmann syndrome Mohr Syndrome
http://www.questdiagnostics.com/kbase/list/ht/m.htm
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MC MCAD Deficiency McArdle Disease McCune Albright Syndrome MCD ... MCTD
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ME ME Measles (Rubeola) Top Mechanical devices for urinary incontinence in women Meckel Syndrome Meckel-Gruber Syndrome MED ... Megalocornea Mental Retardation Syndrome Top Meibomian Cyst Meier-Gorlin Syndrome Meige Syndrome Melanodermic Leukodystrophy ... Meniere's Disease Top Menieres Menieres Disease Meningeal Capillary Angiomatosis Meningeal Fibroblastoma ... Meningitis, Meningococcal

12. Stiff Man Syndrome Information Diseases Database
Stiff man syndrome Stiff person syndrome Stiffman syndrome MoerschWoltman syndrome moersch-woltmann syndrome, Disease Database Information
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Stiff Person Syndrome
Links to information and resources for Stiff Person Syndrome, also known asStiffman Syndrome or moersch-woltmann syndrome.
http://rarediseases.about.com/cs/stiffpersonsynd/
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Guide picks A progressive neurological disorder, also known as Moersch-Woltmann syndrome, having persistent stiffness (rigidity) and spasms of certain muscles. It is thought to be an autoimmune disorder.
The Doctor's Medical Library

Information by Ron Kennedy, MD. Health Living Network Ltd. (U.K.)
Information from Peter Brown, MD, FRCP. KSL-TV: Stiff Man's Syndrome
Short article by KSL-TV, Salt Lake City, Utah, on a local resident with Stiff Person Syndrome, dated May 26, 1999. NINDS: Stiff-Person Syndrome Information
Information sheet from the National Institute for Neurological Disorders and Stroke (U.S.). NORD: Stiff Person Syndrome
Brief definition from the National Organization for Rare Disorders (U.S.).

14. Stiff Person Syndrome
Synonyms. moerschwoltmann syndrome. Muscular Rigidity - Progressive Spasm. SMS. Stiff Man Syndrome. Disorder Subdivisions. None. General
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Diagnose-Me: Condition: Stiff Man Syndrome
Stiff Man Syndrome, also known as moerschwoltmann syndrome or Stiff PersonSyndrome or SPS, is a neuromuscular condition in which a hyperactive startle
http://www.diagnose-me.com/cond/C550180.html
Home FAQ Start The Analyst
Stiff Man Syndrome
Contributing risk factors
Other conditions that may be present Stiff Man Syndrome , also known as Moersch-Woltmann Syndrome or Stiff Person Syndrome or SPS, is a neuromuscular condition in which a hyperactive startle reflex results in the contraction of the muscles, thus causing violent spasms. These spasms are capable of slamming the victim into walls and furniture. The disorder's cause is unknown, although evidence is pointing increasingly to the fact that it is an autoimmune disorder. Stiff person syndrome is rather unique among neurologic diagnoses because of its lack of significant similarity to any other neurologic disease. Although rare, once observed it is quite unforgettable. Possibly the closest related disease is tetanus because both conditions affect peripheral inhibition via central mechanisms and both conditions inhibit central gamma-aminobutyric acid GABA ) systems.
Although they appear completely normal, those afflicted with Stiff Man Syndrome must avoid any situation where they might be exposed to sudden sounds or stimulation. Often, they remain isolated in their home and excluded from normal living - orphaned from society by this rare and ruthless disorder.
SPS is a rare progressive neurological disorder characterized by constant painful contractions and spasms of voluntary muscles, particularly the muscles of the back and upper legs.

16. Stiff Person Syndrome
Synonyms. moerschwoltmann syndrome. Muscular Rigidity - Progressive Spasm. SMS. Stiff Man Syndrome
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Diagnose-Me: Stiff Person Syndrome
Stiff Man Syndrome, also known as moerschwoltmann syndrome or Stiff PersonSyndrome or SPS, is a neuromuscular condition in which a hyperactive startle
http://www.diagnose-me.com/glossary/G1654.html
Home FAQ Start The Analyst
Glossary: Stiff Person Syndrome
Definition Stiff Person Syndrome (SPS) is a rare, progressive neuromuscular condition in which a hyperactive startle reflex results in constant painful contraction of the muscles, thus causing violent spasms of the voluntary muscles, particularly the muscles of the back and upper legs. These spasms are capable of slamming the victim into walls and furniture. The disorder's cause is unknown.
Also: Moersch-Woltmann Syndrome, Stiff Man Syndrome
Topics Related To Stiff Person Syndrome Stiff Man Syndrome The Condition
Stiff Man Syndrome , also known as Moersch-Woltmann Syndrome or Stiff Person Syndrome or SPS, is a neuromuscular condition in which a hyperactive startle reflex results in the contraction of the..."
Last updated: Jun 14, 2005
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18. Stiff Person Syndrome
Links to information and resources for Stiff Person Syndrome, also known as Stiffman Syndrome or moersch-woltmann syndrome.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. Stiff-man Syndrome (a.k.a. Moersch-Woltmann Syndrome)
Stiffman Syndrome (aka moersch-woltmann syndrome) by Ron Kennedy, MD, SantaRosa, California. Stiff-man syndrome, also called Moersch
http://209.15.81.144/sites/_stiff-man_syndrome.html
Stiff-man Syndrome
(a.k.a. Moersch-Woltmann Syndrome)
by Ron Kennedy, M.D., Santa Rosa, California
Stiff-man syndrome, also called Moersch-Woltmann syndrome, is a rare, severe autoimmune neurologic disease involving the central nervous system. Autoimmune disorders are caused when the body's immune system, which is meant to defend the body against bacteria, viruses, and any other foreign product, malfunctions and produces antibodies against healthy tissue, cells and organs. The disease is characterized by a progressive rigidity or stiffness of the muscles caused by a diffuse hypertonia (excess muscular tension or pressure) involving the voluntary muscles of the neck, shoulders, trunk, arms and legs. Painful muscle spasms may also be present. Unlike many autoimmune diseases which have a higher incidence in women, stiff-man syndrome is found more frequently in men. Approximately 70 percent of those afflicted are men. Oddly enough, women can have the stiff-man syndrome.
While the exact cause of stiff-man syndrome is not clear, autoimmunity is thought to be a factor. The frequent occurrence of insulin-dependent diabetes mellitus IDDM ), (also referred to as

20. Stiff Person Syndrome - Quest Diagnostics Patient Health Library
Synonyms. moerschwoltmann syndrome. Muscular Rigidity - Progressive Spasm. SMS. Stiff Man Syndrome
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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