21. Mutation Analysis In The Candidate Mobius Syndrome Genes PGT And Your browser does not support frames. Click here to view the unframed reprint. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

22. IRSC - Rare Disorders, Mobius Syndrome The Internet Resources for Special Children (IRSC) Global disABILITY resource is dedicated to communicating information relating to the needs of children http://www.irsc.org:8080/irsc/irscmain.nsf/sub?readform&cat=Rare Disorders&subca

23. MOBIUS SYNDROME (Search FastHealth.com) MOBIUS SYNDROME mobius syndrome FastHealth Medical Dictionary http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

24. IRSC - Rare Disorders, Mobius Syndrome The Internet Resources for Special Children (IRSC) Global disABILITY resource is dedicated to communicating information relating to the needs of children http://www.irsc.org:8080/irsc/irscmain.nsf/sub?readform&cat=Rare Disorders&subca

25. Mobius Syndrome - Wikipedia, The Free Encyclopedia mobius syndrome (also spelled Moebius) is an extremely rare neurological mobius syndrome is caused by abnormal development of the cranial nerves. http://en.wikipedia.org/wiki/Mobius_syndrome

You did it! Over US$240,000 was donated in the 21 day fund drive. Thank you for your generosity! You are still welcome to make a donation or purchase Wikimedia merchandise Mobius syndrome From Wikipedia, the free encyclopedia. Mobius syndrome Mobius syndrome (also spelled Moebius ) is an extremely rare neurological disorder. Contents Clinical features Treatment Pathological picture External links ... edit Clinical features Mobius syndrome is caused by abnormal development of the cranial nerves . This rare disorder has a number of causes. Most often affected are the cranial nerves VI and VII . Occasionally the cranial nerves V and VIII are affected. If the cranial nerve VI is affected, the patient suffers from loss of lateral gaze. If cranial nerve VII is affected, the patient suffers from bilateral facial palsy — mask-like expressionless face with mouth constantly held open. If cranial VIII is affected the patient suffers from hearing loss. Although its rarity often leads to late diagnosis, Infants with this disorder can be identified at birth: by a "mask-like" expression detectable during crying or laughing due to paralysis (palsy) of the sixth and seventh cranial nerves. Other characteristics include:

26. Foundation For Faces Of Children: Mobius Syndrome How are problems associated with Möbius syndrome corrected? Will Möbius syndrome affect my child s intellectual development? How will Möbius syndrome affect http://www.facesofchildren.org/conditions/mobius.html

Home Craniofacial Conditions What problems is my child likely to have? Can these lead to other problems as my child develops? RECOMMENDED READING "Möbius Syndrome," Cleft Palate Foundation, 104 South Estes Drive, Suite 204, Chapel Hill, NC 27514 Some doctors believe the problem arises when certain nerves in the head and neck do not develop properly; others believe that the nerves begin to develop but are damaged before birth. Still others believe that this rare disorder is related to the development of blood vessels. What problems is my child likely to have? Strabismus , or crossed eyes, is also common. syndactyly (fused fingers or toes), to missing fingers or toes. Can these lead to other problems as my child develops? Another concern as your child gets older is dental problems. Because of facial nerve paralysis and difficulty eating, food may collect around the gums and teeth. To prevent tooth decay, it is very important to keep your child's teeth and gums clean by brushing and flossing. Many children require orthodontic braces later in life.

27. HONselect - Mobius Syndrome Translate this page mobius syndromes - Moebius Syndromes - Syndrome, Mobius. Français, Syndrome de Mobius, - Diplégie faciale congénitale de Moebius - Syndrome de Moebius http://www.hon.ch/HONselect/RareDiseases/C10.292.300.825.html

List of rare diseases: English Deutsch Language: MeSH term: Accepted terms: English: Mobius Syndrome - Congenital Oculofacial Paralysis, Moebius - Moebius Congenital Oculofacial Paralysis - Moebius Syndrome - Mobius Syndromes - Moebius Syndromes - Syndrome, Mobius Français: Syndrome de Mobius - Diplégie faciale congénitale de Moebius - Syndrome de Moebius Deutsch: Moebius-Syndrom Español: Síndrome de Mobius Português: Síndrome de Möbius HONselect ressources Definition: Yes Articles: Yes Images: No News: No Conferences: No Clinical trials: No Web sites: English Yes Français Yes Deutsch No Español No Português No Home About us Site map Search ... Contact http://www.hon.ch/HONselect/RareDiseases/C10.292.300.825.html Last modified: Wed May 18 2005

28. Mobius Syndrome - Congenital Oculofacial Paralysis, Moebius - Information Page W A syndrome of congenital facial paralysis, frequently associated with abducens p http://www.hon.ch/HONselect/RareDiseases/EN/C10.292.300.825.html

InitBulle("navy","#F8F8F8","#000066",1); HONcode sites All Web sites HONselect News ... Images HONselect Search English French German Spanish Portuguese the word the part of word in MeSH term in MeSH term and description Information on "Mobius Syndrome": Medical hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Hierarchy English French German Spanish Portuguese Mobius Syndrome Definition: A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020) Synonym(s): Congenital Oculofacial Paralysis, Moebius / Moebius Congenital Oculofacial Paralysis / Moebius Syndrome / Mobius Syndromes / See also: Facial Paralysis Browse New search Web resources for "Mobius Syndrome" English French German = Site with HON description - = Site with a robot description info: enter the site: (click below) domain of the site: HONcode - www.emedicine.com

29. MOEBIUS SYNDROME NEWS NEWSLETTER MOBIUS SYNDROME CRANIAL NERVE NERVES Moebius Syndrome Book. Questions/Answers. Thank You s. Gentler Method Club Foot. Mother In England. Erik From Peru. Benefit Concert For Moebius . http://www.moebius1.org/newsletter_jan_2000.html

Vol. IX No. 2 Editor: vmccarrell@mid-mo.net SITE INDEX MORE NEWS Aug. 2000 4th International Moebius Conference Edition Conference Overview Stars Come Out At Night Up-Coming Get Togethers Halverson Attends Conference ... easchum@warwick.net ; 914-831-5221. Send Elisa a check for $10, which includes shipping, to the Moebius Syndrome Foundation with your name and address. We still have a few conference canvas bags with the logo left and many XL conference t-shirts. Cost of the bags is $10 each, cost of the t-shirts is $15 - both also available from Elisa. To order audio tapes of the conference send your request, with $20 per tape, to Marsha Roach, 722 Vauxhall Street Ext, Waterford, CT 06385-4354; 860-437-8396. marsha_l_roach@groton.pfizer.com To order video tapes of the speakers contact ProMedia, 2593 Hamline Avenue, Roseville, MN 55133; 612-631-3681. The tapes cost $25 each. A study in Sweden has identified the drug Misoprostol, which causes uterine contractions and was used to induce abortion in South America, (the drug is illegal in the U.S.) as a cause of Moebius Syndrome where use of the drug failed to cause an abortion. In these cases, a vascular disruption occurred in the uterus between 23-46 days gestation. For more information go to: http://omie.med.jhmi.edu/craniofacial

30. GUIDE - CHAPTER 3 Our 7 yr old son, Kieran, we believe, has mobius syndrome. We have just discovered there *is* a mobius syndrome! He was born with left side facial paralysis http://www.moebius1.org/chapter_3.html

MOEBIUS1.ORG MODEL: MOEBIUS SYNDROME SITE INDEX GUIDE INDEX EMAIL SOLID FOODS Chapter 3 - Parent's Guide My name is Gena, my husband's name is Jeff, and we have two sons, 7 and 2.  Our 7 yr old son, Kieran, we believe, has Mobius Syndrome.  We have just discovered there *is* a Mobius Syndrome! He was born with left side facial paralysis, he didn't blink his left eye for months (one of my biggest worries for him!), had some troubles breastfeeding as an infant (that we were able to overcome!!!), and has always had issues with choking on certain types of foods.  He has always had a love of intensely flavored food, and as a toddler would devour a bowl of curried onions!  Now, we realize it is because he probably has limited taste, which also explains teething on dill pickles, a fondness for strong european cheeses, preferring course whole grain breads, etc, not exactly what one would think of as 'kid' food :) Gena PREVIOUS PAGE NEXT CHAPTER If you can contribute to the development of this project it will be greatly appreciated. Feel free to contact us at any time and on any topic.

31. Mobius Syndrome - Patient UK mobius syndrome Patient UK. A directory of UK health, disease, illness and related medical websites that provide patient information. http://www.patient.co.uk/showdoc/40001491/

PatientPlus articles are written for doctors and so the language can be technical. However, some people find that they add depth to the articles found in the other sections of this website which are written for non-medical people. Mobius Syndrome Mobius sequence/syndrome (Congenital facial diplegia) This is the association of congenital bilateral facial weakness with ophthalmoplegia and absent trapezius or pectoral muscles. Other features: feeding difficulty, IQ low (in 50%), expressionless face syndactyly , oligodactyly, brachydactyly, club foot arthrogryposis and other limb deformities. There is no clear genetic cause, but misoprostol, ergotamine, and chorionic villus sampling have been implicated. References: M Baraitser 1977 J Med Genet TH Shepard 1995 Lancet Last issued 01 Jun 2004 Sponsored links and adverts Patient UK has no control of the content of the following links. Inclusion does not imply endorsement by Patient UK. Health Related Books From Amazon - browse hundreds of books on health and disease. Also, worth a look... Related pages in Patient UK Patient Support UK Moebius Syndrome Support Group Your Experience Please add your comments about this condition.

32. Mobius Syndrome - Information & News The study found that when a development gene named Hoxb1 worked in a mouse?s brain but not in the developing facial tissues, nerves extended outward from http://www.news-medical.net/?keyword=Mobius syndrome

33. Simple Genetic Code Might Work To Wire Up The Body From Head To Foot similar to the mutant mice a rare birth defect named mobius syndrome, yet known if a mutation of the Hoxb1 gene plays a role in mobius syndrome, http://www.news-medical.net/?id=2443

34. Mobius Syndrome mobius syndrome, congenital facial diplegia with restriction of lateral Neurology Developmental malformations of the nervous system mobius syndrome http://www.medlink.com/PublicCIP.ASP?access=public&UID=MLT000HD&code=

35. Mobius Syndrome Topic - Unified Search Environment mobius syndrome Topic Tree mobius syndrome MSH/MH/D020331 MTH/PN/NOCODE DXP/DI/U001193 MSH/EN/D020331 MSH/PM/D020331 MSH/PM/D020331 http://www.use.hcn.com.au/portals/shared/subject.`Mobius Syndrome`/home.html

Mobius Syndrome Topic Tree Definition: A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020) Synonyms and Source Vocabularies: Mobius Syndrome CONGENITAL NUCLEAR APLASIA CONGENITAL FACIAL DIPLEGIA SYNDROME PARALYSIS, OCULOFACIAL, CONGENITAL Moebius Congenital Oculofacial Paralysis Hypoglossia-hypodactyly syndrome Congenital Abnormality Abnormalities, Drug-Induced Abnormalities, Multiple Basal Cell Nevus Syndrome Beckwith-Wiedemann Syndrome Bloom Syndrome Cockayne Syndrome ... Congenital neurologic anomalies

36. Symptoms Of Mobius Syndrome - CureResearch.com Symptoms of mobius syndrome including signs, symptoms, incubation period, duration, and correct diagnosis. http://www.cureresearch.com/m/mobius_syndrome/symptoms.htm

IMPORTANT! Use of this site is subject to our Home Contents Diseases Search Search: Condition Lists By Organ By Class By Prevalence By Deaths ... Full List Current chapter: Mobius syndrome Next sections Associated Conditions of Mobius syndrome Treatments for Mobius syndrome Statistics about Mobius syndrome Statistics by Country for Mobius syndrome Next chapters: Neuronal Migration Disorders Holoprosencephaly Congenital malformations Cleft palate ... Malpractice Symptoms of Mobius syndrome General information about symptoms of Mobius syndrome: The symptom information on this page attempts to provide a list of some possible symptoms of Mobius syndrome. This symptom information has been gathered from various sources, may not be fully accurate, and may not be the full list of symptoms of Mobius syndrome. Furthermore, symptoms of Mobius syndrome may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of symptoms and whether they are indeed symptoms of Mobius syndrome. List of symptoms of Mobius syndrome: The list of symptoms mentioned in various sources for Mobius syndrome includes: Facial paralysis Lack of facial expression Inability to smile Some additional symptoms in newborns include: Inability to suck (infant) Feeding difficulty Difficulty swallowing Choking problems (infant) ... Mental retardation Symptoms of Mobius syndrome: In newborns, the first symptom is an inability to suck. Excessive drooling and strabismus (crossed eyes) may occur. Other symptoms may include lack of facial expression; inability to smile; feeding, swallowing, and choking problems; eye sensitivity; motor delays; high or cleft palate; hearing problems; and speech difficulties. Deformities of the tongue, jaw, and limbs, such as club foot and missing or webbed fingers, may also occur. Most patients have low muscle tone, especially in the upper body. Mental retardation may also occur. As children get older, lack of facial expression and inability to smile become the dominant visible symptoms.

37. Prognosis Of Mobius Syndrome - CureResearch.com Prognosis of mobius syndrome including probably outcomes, duration, recurrence, complications, deaths, and survival rates. http://www.cureresearch.com/m/mobius_syndrome/prognosis.htm

IMPORTANT! Use of this site is subject to our Home Contents Diseases Search Search: Condition Lists By Organ By Class By Prevalence By Deaths ... Full List Current chapter: Mobius syndrome Next sections Symptoms of Mobius syndrome Associated Conditions of Mobius syndrome Treatments for Mobius syndrome Statistics about Mobius syndrome ... Statistics by Country for Mobius syndrome Next chapters: Neuronal Migration Disorders Holoprosencephaly Congenital malformations Cleft palate ... Malpractice Prognosis of Mobius syndrome About prognosis: The 'prognosis' of Mobius syndrome usually refers to the likely outcome of Mobius syndrome. The prognosis of Mobius syndrome may include the duration of Mobius syndrome, chances of complications of Mobius syndrome, probable outcomes, prospects for recovery, recovery period for Mobius syndrome, survival rates, death rates, and other outcome possibilities in the overall prognosis of Mobius syndrome. Naturally, such forecast issues are by their nature unpredictable. Prognosis for Mobius syndrome: There is no cure for Mobius syndrome. With proper care and treatment many individuals have normal life expectancy, in spite of the severe impairments that characterize the disorder.

38. Mobius Syndrome Complete online version of The Encyclopaedia of Medical Imaging including text and images from The Encyclopaedia of Medical Imaging s eight book volumes http://www.amershamhealth.com/medcyclopaedia/medical/Volume VI 2/MOBIUS SYNDROME

financial services our commitment our company Search Medcyclopaedia for: Search marked text (mark text before you click) Browse entry words starting with: A B C D ... amershamhealth.com Mobius' syndrome, (Paul Julius Mobius, 18531907, German neurologist), congenital bilateral facial paralysis, due to total or partial absence of the facial nerve. Patients also have palsy of the abducens nerves and may have additional cranial nerve abnormalities. Various ear abnormalities may be present, such as deformation of the auricle and malformations of the inner ear . The abnormalities may be unilateral. The syndrome is known to be associated with a variety of other developmental somatic defects. RH The Encyclopaedia of Medical Imaging Volume VI 2 Corporate Products Financial Services Our Commitment ... Terms of Conditions

39. Moebius Syndrome Congenital Facial Diplegia Syndrome; Congenital Oculofacial Paralysis; mobius syndrome; Moebieus Sequence. Disorder Subdivisions. None. General Discussion http://my.webmd.com/hw/raising_a_family/nord451.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report Moebius Syndrome Important It is possible that the main title of the report Moebius Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Congenital Facial Diplegia Syndrome Congenital Oculofacial Paralysis Mobius Syndrome Moebius Sequence Disorder Subdivisions None General Discussion Moebius syndrome is a rare developmental disorder present at birth (congenital) that is characterized by facial paralysis. Affected individuals are not able to smile or frown because two important nerves, the sixth (abducens) and seventh (facialis) cranial nerves are absent or not fully developed. In some instances, this syndrome may also be associated with physical problems in other parts of the body. Resources Children's Craniofacial Association 13140 Coit Road Suite 307 Dallas, TX 75240

40. Moebius Syndrome Synonyms. Congenital Facial Diplegia Syndrome; Congenital Oculofacial Paralysis; mobius syndrome; Moebieus Sequence. Disorder Subdivisions. None http://www.bchealthguide.org/kbase/nord/nord451.htm

var hwPrint=1;var hwDocHWID="nord451";var hwDocTitle="Moebius Syndrome";var hwRank="1";var hwSectionHWID="nord451-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Moebius Syndrome Important It is possible that the main title of the report Moebius Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Congenital Facial Diplegia Syndrome Congenital Oculofacial Paralysis Mobius Syndrome Moebieus Sequence Disorder Subdivisions None General Discussion Moebius syndrome is a rare developmental disorder present at birth (congenital) that is characterized by facial paralysis. Affected individuals are not able to smile or frown because two important nerves, the sixth (abducens) and seventh (facialis) cranial nerves are absent or not fully developed. In some instances, this syndrome may also be associated with physical problems in other parts of the body. Resources Children's Craniofacial Association 13140 Coit Road Suite 307 Dallas, TX 75240

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