1. Mobius Syndrome mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or underdevelopment of the 6th and 7th cranial nerves. http://healthlink.mcw.edu/article/921441372.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Mobius Syndrome Mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or underdevelopment of the 6th and 7th cranial nerves. These nerves control eye movements and facial expression. In newborns, the first symptom is an inability to suck. Excessive drooling and strabismus (crossed eyes) may occur. Other symptoms may include lack of facial expression; inability to smile; feeding, swallowing, and choking problems; eye sensitivity; motor delays; high or cleft palate; hearing problems; and speech difficulties. Deformities of the tongue, jaw, and limbs, such as club foot and missing or webbed fingers, may also occur. Most patients have low muscle tone, especially in the upper body. Mental retardation may also occur. As children get older, lack of facial expression and inability to smile become the dominant visible symptoms. Mobius syndrome may be accompanied by Pierre Robin syndrome, a disease in which there is an abnormally small jaw, downward displacement of the tongue, and a soft, cleft palate. It may also be accompanied by Poland's anomaly, a disease characterized by abnormal development of one side of the chest and limb deformities.

2. NINDS Forwarding Page Also known as congenital facial diplegia, an information sheet compiled by NINDS. http://www.ninds.nih.gov/health_and_medical/disorders/mobius.htm

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3. Mobius Syndrome mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or underdevelopment of the 6th and 7th cranial http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. Mobius Syndrome Information Page: National Institute Of Neurological Disorders A mobius syndrome (Congenital Facial Diplegia) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). http://www.ninds.nih.gov/disorders/mobius/mobius.htm

Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system More about Mobius Syndrome Studies with patients Research literature Press releases Search NINDS... (help) Contact Us My Privacy NINDS is part of the National Institutes of Health You are here: Home Disorders Mobius Syndrome NINDS Mobius Syndrome Information Page Synonym(s): Congenital Facial Diplegia Get Web page suited for printing Email this to a friend or colleague Table of Contents (click to jump to sections) What is Mobius Syndrome? Is there any treatment? What is the prognosis? What research is being done? ... Organizations What is Mobius Syndrome? Is there any treatment? There is no specific course of treatment for Mobius syndrome. Treatment is supportive and in accordance with symptoms. Infants may require feeding tubes or special bottles to maintain sufficient nutrition. Surgery may correct crossed eyes and improve limb and jaw deformities. Physical and speech therapy often improves motor skills and coordination, and leads to better control of speaking and eating abilities. Plastic reconstructive surgery may be beneficial in some individuals. Nerve and muscle transfers to the corners of the mouth have been performed to provide limited ability to smile. What is the prognosis?

5. Mobius Syndrome Information Page National Institute Of mobius syndrome (Congenital Facial Diplegia) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. Introduction: Mobius Syndrome - WrongDiagnosis.com Introduction to mobius syndrome as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis. http://www.wrongdiagnosis.com/m/mobius_syndrome/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Mobius syndrome Next sections Basic Summary for Mobius syndrome Prevalence and Incidence of Mobius syndrome Prognosis of Mobius syndrome Symptoms of Mobius syndrome ... Associated Conditions of Mobius syndrome Next chapters: Neuronal Migration Disorders Holoprosencephaly Congenital malformations Cleft palate ... Feedback Introduction: Mobius syndrome Mobius syndrome: Type of facial paralysis. Mobius syndrome: Mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or underdevelopment of the 6th and 7th cranial nerves. These nerves control eye movements and facial expression. Researching symptoms of Mobius syndrome: Further information about the symptoms of Mobius syndrome is available including a list of symptoms of Mobius syndrome , or alternatively return to research other symptoms in the symptom center Treatments for Mobius syndrome: Various information is available about treatments available for Mobius syndrome , or research treatments for other diseases.

7. Biology Symptoms, diagnosis, and treatment of mobius syndrome. Information on research, community outreach and support. http://genetics.about.com/science/genetics/library/blmob.htm

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') About Homework Help Biology Homework Help ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Biology newsletter! See Online Courses Search Biology From Regina Bailey Your Guide to Biology FREE Newsletter. Sign Up Now! Grasshopper Suicide Scientists have discovered that parasitic hairworms cause their host to commit suicide in order to increase their chances of survival. As the hairworm grows inside its host, a grasshopper for example, it secretes chemicals that make the host dive into water and drown. Thursday September 08, 2005 Aphid Helping Bacteria Researchers have discovered that bacterial symbiotes are responsible for the resistance of certain aphids to wasps . Aphids must avoid these wasps who seek to lay their eggs inside the aphids. Wednesday September 07, 2005 Brain Anatomy: Substantia Nigra Located in the midbrain region, the substantia nigra is involved in controlling voluntary movement and regulating mood. Saturday September 03, 2005

8. MOEBIUS SYNDROME NEWS NEWSLETTER MOBIUS SYNDROME CRANIAL NERVE Growing Old With Moebius. NACD. Annilea, A New Book. Moebius Syndrome Book. Questions/Answers. Thank You's. Gentler Method Club Foot. Mother http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. Article: NINDS Mobius Syndrome Information Page: NINDS - WrongDiagnosis.com Medical article NINDS mobius syndrome Information Page NINDS including all symptom, diagnosis, misdiagnosis, treatment and prevention information. http://www.wrongdiagnosis.com/artic/ninds_mobius_syndrome_information_page_ninds

Home Symptoms Diseases Risks ... Newsletter Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: NINDS Mobius Syndrome Information Page: NINDS Next chapters: NINDS Monomelic Amyotrophy Information Page: NINDS NINDS Motor Neuron Diseases Information Page: NINDS NINDS Moyamoya Disease Information Page: NINDS NINDS Mucopolysaccharidoses Information Page: NINDS ... Feedback NINDS Mobius Syndrome Information Page: NINDS Article title: NINDS Mobius Syndrome Information Page: NINDS Main condition: Mobius syndrome Conditions: Mobius syndrome What is Mobius Syndrome? Is there any treatment? There is no specific course of treatment for Mobius syndrome. Treatment is supportive and symptomatic. Infants may require feeding tubes or special bottles to maintain sufficient nutrition. Surgery may correct strabismus and improve limb and jaw deformities. Physical and speech therapy may improve motor skills and coordination, and help to better control speaking and eating abilities. Plastic reconstructive surgery may be beneficial in some individuals. Also, in a few cases, nerve and muscle transfers (microvascular muscle transplant) to the corners of the mouth have been performed to provide some ability to smile. What is the prognosis?

10. Reader's Digest - Rd.com A list of alternate names for mobius syndrome, along with a general discussion and resources. http://www.rd.com/common/nav/index.jhtml?articleId=8612437

11. Mobius Syndrome mobius syndrome. This article submitted by Shawn K. Centers, DO on 4/14/95. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. Mobius Syndrome mobius syndrome. This article submitted by Shawn K. Centers, DO on 4/14/95. mobius syndrome is a conginital disorder involving (1)complete or partial VIIth http://neuro-www.mgh.harvard.edu/neurowebforum/ChildNeurologyArticles/MobiusSynd

Mobius Syndrome This article submitted by Shawn K. Centers, DO on 4/14/95. Mobius syndrome is a conginital disorder involving (1)complete or partial VIIth nerve palsy (2)abducens palsy (3) limb malformations especially talipes (3) less commonly there may be palsies of the Vth, IXth, and XXIIth CN's. There have been less than 80 reported cases in the literature. I am interested in the pathogenesis of this disorder and any additional known cases. Next Article Previous Article Return to Topic Menu Here is a list of responses that have been posted to this article... Rea Respiratory Palsy (1/14/97) 8:35 PM Nerve Transplant IN Moebius (12/21/96) 2:30 PM Nerve Transplanted (12/21/96) 12:31 PM Leslie (12/19/96) 2:16 PM ... Mobius Syndrome (5/16/95) 2:10 PM You now have TWO OPTIONS: Post a new Article or post a Response to this Article Click here to post a new Article! If you would like to post a Response to this article, fill out this form completely... Do not use slashes ("/") or colons (":") in your Article title! Response Title: Author: Response Text: Original Article: (Don't change this field!)

13. MOBIUS SYNDROME mobius syndrome. mobius syndrome is a rare congenital disturbance consisting of varying involvement of facial and lateral gaze paresis. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. Mobius Syndrome understand it, current thinking suggests that mobius syndrome a literature search of mobius syndrome that was published (? in Peds http://neuro-www.mgh.harvard.edu/neurowebforum/ChildNeurologyArticles/MobiusSynd

Mobius Syndrome This response submitted by Barry Kosofsky- MGH Child Neuro on 5/16/95. Dr. Centers, Sorry for the delay, but we are just coming on-line. As I understand it, current thinking suggests that Mobius Syndrome may result from a vascular field defect (ie. failure of perfusion of a specific vessel during fetal life, with maldevelopment of the neural, muscular, and other tissue structures normally perfused by that vessel). There was an article that you should be able to pull from a literature search of "Mobius Syndrome" that was published (? in Peds or J Peds, or Teratology) about 2 years ago that dicusses this theory (and other field defects such as POLAND Syndrome). Good Luck, Barry E. Kosofsky, M.D., Ph.D. Next Article Return to Main Article Article complete. Click HERE to return to the Neurology Web-Forum Menu.

15. MOEBIUS SYNDROME SUPPORT NETWORK HOMEPAGE Bringing together information from and links to medical and lay support for those affected by Moebius syndrome. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Mobius Syndrome mobius syndrome. Synonym(s) Congenital Facial Diplegia. What is mobius syndrome? mobius syndrome, a rare genetic disorder characterized by facial paralysis http://www.clevelandclinic.org/health/health-info/docs/1300/1307.asp?index=6064&

17. Mobius Syndrome - StopGettingSick News mobius syndrome StopGettingSick News http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. Show-documents.asp mobius syndrome Written Information. Care Treatment. , mobius syndrome New Search Health Extra Menu. http://www.clevelandclinic.org/healthextra/do-query.asp?TopicId=1329

19. Mutation Analysis In The Candidate Mobius Syndrome Genes PGT And F, Brunoni D, Schwarz IV, Larrandaburu M, Safattle H, Meloni VF, Koren G. Use of misoprostol during pregnancy and Mobius' syndrome in infants. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

20. MOBIUS SYNDROME mobius syndrome is a rare congenital disturbance consisting of varying Clinical Manifestations mobius syndrome is characterized by unilateral or http://www.members.aol.com/scottolitsky/mobius.htm

MOBIUS SYNDROME Mobius syndrome is a rare congenital disturbance consisting of varying involvement of facial and lateral gaze paresis. Mobius first suggested that congenital bilateral abducens-facial paralysis might be an independent pathologic entity, thus gaining eponymic distinction. Clinical Manifestations Mobius syndrome is characterized by unilateral or bilateral inability to abduct the eyes. Although horizontal movements are usually lacking, vertical movements and convergence are intact. Pupillary constriction, vision, and the retina are generally normal. Congenital esotropia is common in children with Mobius syndrome. In a retrospective study of 61 patients with this syndrome, 38 per cent had early-onset esotropia. The unilateral or bilateral complete or incomplete facial palsy is usually observed during the first few weeks of life because of difficulty with sucking and feeding, and incomplete closure of the eyelids during sleep. These patients typically have masklike faces with an inability to grin and wrinkle the forehead. Mobius syndrome is frequently associated with paresis of other muscles supplies by the cranial nerves. Often, there is partial atrophy of the tongue with inability to protrude the tongue beyond the lips. Paralysis of the soft palate and muscles of mastication may also occur. Various skeletal and muscle defects are common, including absence or hypoplasia of the pectoral muscles, syndactyly, club feet, and congenital limb amputations.

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