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         Miller Fisher Syndrome:     more detail
  1. The Official Patient's Sourcebook on Miller Fisher Syndrome: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-10
  2. Fisher syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Bryan, PhD Cobb, 2005

81. Charles Miller Fisher (www.whonamedit.com)
Charles miller fisher Canadian neurologist, born 1913, Waterloo, Ontario.Associated with GuillainBarré-Strohl syndrome,miller fisher s syndrome.
http://www.whonamedit.com/doctor.cfm/1466.html

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Charles Miller Fisher Canadian neurologist, born 1913, Waterloo, Ontario. Associated eponyms: Guillain-Barré-Strohl syndrome The commonest form of acquired neuropathy, most frequently affecting young adults. Commences with progressive muscular weakness of extremities that may lead to paralysis. Miller Fisher's syndrome A disturbance thought to be a variant of the Guillain-Barré syndrome usually characterised by total external ophthalmoplegia, ataxia, and loss of tendon reflexes. Biography: Charles Miller Fisher graduated from the University of Toronto Medical School in 1938. During the Second World War he was in a German prison camp for three and a half years. He became the doctor for the other prisoners and took the opportunity to learn German. This would later allow him, upon his return home to Canada, to access important original German literature regarding cerebrovascular disease.

82. GBS
Pure motor syndrome (IgG vs GM1); millerfisher syndrome (IgG vs GQ1b) miller-fisher syndrome 1% of childhood AIDP; CNS signs More frequent; At onset
http://www.neuro.wustl.edu/neuromuscular/antibody/gbs.htm

Front
Search Index Links ... Patient Info
Acute Immune Polyneuropathies
"Classic" Guillain-Barré Syndrome
Associated disorders

Childhood GBS

Clinical features
...
Sensory

Cranial nerve variants
Bickerstaff

Miller Fisher Syndrome

Pharyngo-cervico-brachial

IgM vs GalNAc-GD1a
General topics Classification: Acute immune neuropathies Differential diagnosis: Acute neuromuscular disorders General Principles: Acute immune neuropathies Treatment of GBS-like syndromes ... Antibodies Guillain Also see: GBS history
Classification of Acute Immune Neuropathies
  • Motor + Sensory
    • CIDP with acute onset: More prominent demyelination on NCV
    Motor
  • Axonal
  • Cranial Nerve Syndromes: Associated with
  • Other GBS variants with autoantibodies
    Acute immune neuropathies: General principles
    Acute immune neuropathies have several features in common as well as those that vary and are distinctive for a particular syndrome. Some features suggest a
  • 83. Miller-Fisher Syndrome - General Practice Notebook
    millerfisher syndrome is a rare variant of Guillain-Barre syndrome comprising.ataxia; ophthalmoplegia; areflexia. Like the Guillain-Barre,
    http://www.gpnotebook.co.uk/cache/-1395654646.htm
    Miller-Fisher syndrome Miller-Fisher syndrome is a rare variant of Guillain-Barre syndrome comprising:
    • ataxia ophthalmoplegia areflexia
    Like the Guillain-Barre, the Miller-Fisher syndrome is a post-infective polyneuropathy, with the nerves supplying the ocular muscles most often affected. It has a good prognosis.
    Click here for more information...

    84. Guillain-Barre Syndrome,Ascending Paralysis,Acute Idiopathic
    Disorder Subdivisions millerfisher syndrome Fischer s syndrome Acute DisseminatedEncephalomyeloradiculopathy Chronic Guillain-Barre syndrome
    http://www.icomm.ca/geneinfo/guillian.htm

    85. Miller-Fisher Syndrome Info?
    millerfisher syndrome info? This article submitted by Jack Creegan on 12/9/95.I am looking for sources of information on miller-fisher syndrome.
    http://neuro-www.mgh.harvard.edu/neurowebforum/GeneralFeedbackArticles/MillerFis
    Miller-Fisher Syndrome info?
    This article submitted by Jack Creegan on 12/9/95.
    I am looking for sources of information on Miller-Fisher syndrome. Can you direct me to any, on or off line? Next Article
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    86. All About Guillain-Barré Syndrome: Syndrome Facts At A Glance.
    MFS (millerfisher syndrome), Also known as miller Fish syndrome, miller s syndromeand Acute Disseminated Encephalo-myeloradiculopathy.
    http://www.jsmarcussen.com/gbs/print/overview.htm
    - GBS at a glance -
    GBS - Facts at a glance
    What is a 'Syndrome'?

    The many names of the syndrome

    Variants of GBS
    ...
    Further reading
    GBS - Facts at a glance
    Guillain-Barré Syndrome (GBS) is a rare inflammation of the nerves, caused by the patient's body producing antibodies against the peripheral nerves. The syndrome affects each patient differently and so the course of the disease differs for each patient.
    How and why one contracts GBS is as yet unknown. The syndrome is typically observed after an infection in the lungs, diarrhoea, surgery, vaccination or childbirth.
    The inflammation damages portions of the nerve cell, resulting in muscle weakness, paralysis or sensory disturbances. The damage usually involves loss of the nerve's myelin sheath (demyelination), which slows the conduction of impulses through the nerve.
    The damage may also involve destruction of the axon part of the nerve cell (denervation), which

    87. All About Guillain-Barré Syndrome - David Cleal's Case As A Miller-Fisher Suffe
    millerfisher syndrome written by his wife. My husband David is a charteredaccountant practicing in the South Wairarapa. About 12 years ago – December 1990
    http://www.jsmarcussen.com/gbs/print/david.htm
    - Case Histories -
    David Cleal , New Zealand
    Miller-Fisher syndrome
    written by his wife
    The dates below are approximate but give you a pretty accurate idea of the time span involved in such a case. At the hospital a doctor was present when David tried to eat some jelly and could not swallow it. By repeating the tests done by the GP during the day they were able to assess the progress of the still undiagnosed problem. During the night his condition worsened, and he was extremely embarrassed when he fell down while going into the toiled to deal with yet another bout of diarrhea, completely losing control of both feet and bowel functions. Monday the 13th December the decision was made to transfer him to Wellington Hospital and the doctor and a nurse accompanied him in an ambulance. Breathing had become difficult and movement of arms and legs almost ceased. David panicked (and so did the Masterton doctor) when David was left in the Emergency admissions for over an hour because the orderlies were at lunch.
    Tests identified the presence of Campylobactor, probably the catalyst for the infection and resulting syndrome.

    88. Miller-fisher Syndrome A Variant Of Guillian Barre Syndrome : A Case Report
    Medical Journal Armed Forces India. 1986 Jul; 42(3) 2312.
    http://medind.nic.in/imvw/imvw22796.html
    Extracted from IndMED Narula AS; Rana PVS; Narula HS Dept. of Medicine, Command Hospital (SC), Pune 400 040, (Maharashtra) Miller-fisher syndrome a variant of guillian barre syndrome : a case report Medical Journal Armed Forces India. 1986 Jul; 42(3): 231-2 ABSTRACT: A case of Miller-Fisher Syndrome has been presented. This is an unusual variant of Guillian Barre Syndrome. Relevant literature has also been reviewed. KEYWORDS: Polyradiculoneuritis/DI; Polyradiculoneuritis/DT; Prednisolone/AD; Middle Age; case Report References: 8 Record Identifier: NI209465

    89. Guillain-Barre Syndrome
    millerfisher syndrome The most common subtype is miller-fisher syndrome (MFS), miller-fisher syndrome associated with Campylobacter jejuni bearing
    http://www.davidson.edu/academic/psychology/ramirezsite/neuroscience/psy324/jeca
    This web page was produced as an assignment for an undergraduate course at Davidson College.
    Guillain-Barre Syndrome
    Table of Contents History Of Guillain-Barre Syndrome Epidemiology Causes Pathogenesis ... Subtypes of Guillain-Barre Syndrome History
    In 1859, Jean B.O. Landry, a French physician, described a disorder in which the nerves of the legs, arms, neck, and breathing muscles were paralyzed. Georges Guillain, Jean Alexander Barre, and Andre Strohl discovered the characteristic abnormality of increased protein but normal cell count in the cerebrospinal fluid in 1916. Several names have been given for the syndrome including acute idiopathic polyneuritis, acute idiopathic polyradiculoneuritis, Landry’s ascending paralysis, and Guillain Barre syndrome.
    Back to the top
    Epidemiology
    Back to the top
    Causes
    The causes of Guillain Barre syndrome are unknown. Many researchers theorize that the autoimmune reaction in which macrophages and T-cells attack myelin in the peripheral and cranial nerves is associated with a bacteria or virus, as many cases occur a few days to a few weeks after an infection including the common cold, sore throat, and stomach and intestinal viruses with vomiting and diarrhea. The virus might induce the demyelination via a possible mimicry between the effector virus and a human ganglioside. Salloway and colleagues (1996) discovered that the lipopolysaccharide structure of some strains of Campylobacter jejuni , specifically, the terminal structures of the core oligosaccharide, resemble the human gangliosides GM1 and GD1a. A possible mimicry also exists between the influenza A NS2 protein and a sequence region of the human P2 (myelin) protein thought to be neuritogenic in animals and mitogenic for lymphocytes from patients with GBS. This finding could provide a possible link between the large number of cases of GBS associated with the 1976 USA swine flu vaccination program (Weise and Carnegie, 1988).

    90. EMedicine - Guillain-Barré Syndrome : Article By David Fanion, MD
    GuillainBarré syndrome - Classic Guillain-Barré syndrome (GBS) is an acute,ascending, A variation known as the miller-fisher variant is unusual,
    http://www.emedicine.com/EMERG/topic222.htm
    (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Emergency Medicine Neurology
    Last Updated: August 14, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: GBS, acute idiopathic polyneuritis AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography
    Author: David Fanion, MD , Consulting Staff, Department of Emergency Medicine, AO Fox Hospital Coauthor(s): David Fanion, MD , Consulting Staff, Department of Emergency Medicine, AO Fox Hospital David Fanion, MD, is a member of the following medical societies: American Academy of Emergency Medicine Editor(s): Edward A Michelson, MD , Program Director, Associate Professor, Department of Emergency Medicine, University Hospital Health Systems in Cleveland; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, eMedicine; J Stephen Huff, MD

    91. EMedicine - Guillain-Barre Syndrome : Article Excerpt By: Angela Cha-Kim, MD
    The millerfisher syndrome is a common variant of GBS and is observed in about5% of all GBS cases. The syndrome consists of ataxia, ophthalmoplegia,
    http://www.emedicine.com/pmr/byname/guillain-barre-syndrome.htm
    (advertisement)
    Excerpt from Guillain-Barre Syndrome
    Synonyms, Key Words, and Related Terms: Guillain-Barré syndrome, GBS, acute inflammatory demyelinating polyradiculoneuropathy, AIDP, Landry-Guillain-Barré syndrome, Landry-Guillain-Barré-Strohl syndrome, acute idiopathic neuropathy, acute demyelinating neuropathy, infectious polyneuritis, acute polyradiculoneuritis, axonal Guillain-Barré syndrome, acute motor axonal neuropathy, AMAN, acute motor-sensory axonal neuropathy, AMSAN, Miller-Fisher syndrome, pharyngeal-cervical-brachial GBS
    Please click here to view the full topic text: Guillain-Barre Syndrome
    Background: Guillain-Barré syndrome (GBS) is described most accurately as a collection of clinical syndromes manifested by an acute inflammatory polyradiculoneuropathy with resultant weakness and reflex changes. With poliomyelitis under control in developed countries, GBS is now the most important cause of acute flaccid paralysis. GBS remains a diagnosis made primarily by clinical history and findings. Though classically thought of as a demyelinating neuropathy with ascending weakness, many clinical variants have been well documented in the medical literature. Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is the most widely recognized form in Western countries, but the recently described variants of acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN) also are well recognized. Many believe that strictly defined subgroups of GBS are not distinguished easily but that the subgroups exist, based on a clinical spectrum of symptoms and findings.

    92. Bioline International Official Site (site Up-dated Regularly)
    Our patient with recurrent millerfisher syndrome (MFS) had no antecedent illnessduring the second episode as mentioned in the case report.1 Antecedent
    http://www.bioline.org.br/request?ni03091

    93. Fýrat Týp Dergisi
    A Case Of millerfisher syndrome Displaying A Fast Improvement Following Intravenous miller-fisher syndrome is a rare and benign form of Guillain-Barre
    http://www.firattipdergisi.com/summary_en.php3?id=125

    94. Miller Fisher, Syndrome : Arborescences MeSH
    maladies C10
    http://www.chu-rouen.fr/navimesh/M/navimillerfishersyndrome.html
    Miller fisher, syndrome : arborescences MeSH Menu général CISMeF Vous pouvez aussi consulter toutes les arborescences des mots clés utilisés dans CISMeF

    95. Syndrome De Miller-fisher : Arborescences MeSH

    http://www.chu-rouen.fr/navimesh/S/navisyndromedemillerfisher.html
    Syndrome de miller-fisher : arborescences MeSH Vous pouvez aussi consulter toutes les arborescences des mots clés utilisés dans CISMeF

    96. Miller-Fisher Syndrome Associated With Campylobacter Jejuni Bearing Lipopolysacc
    millerfisher syndrome associated with Campylobacter jejuni bearing lipopolysaccharidemolecules that mimic human ganglioside GD3. S Salloway, LA Mermel,
    http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=174172

    97. Pathogenic Blocking Antibodies In Guillain-Barre Syndrome
    Pre and postsynaptic blockade of synaptic transmission by miller-fisher syndromeIgG at mouse motor nerve terminals.. European Journal of Neuroscience,
    http://www.zv.uni-wuerzburg.de/forschungsbericht/FOBE-akt/IN-30502000/Toyka DFG

    nameindex
    key word index to: corresp.unit home: research report
    Third-party-funded project
    Title:
    Pathogenic blocking antibodies in Guillain-Barre Syndrome Project management at the University of Würzburg: Participating scientists: Abstract:
    The Guillain-Barre Syndrome is the most common inflammatory peripheral nerve disorder with a mortality of up to 8 per cent and longstanding disability in almost half of the patients. The project deals with the recently identified blocking IgG autoantibodies which may act in concert with cell mediated immune mechanisms and complement. These antibodies have a unique dual action with presynaptic blockade of calcium current and of postsynaptic acetyl choline receptor channels. The project deals with the precise mechanisms as analyzed by electrophysiological patch clamp technology. These autoantibodies are likely directed to membrane gangliosides and can be neutralized by polyclonal immunoglobulins from healthy humans. Key words:
    Guillain-Barré Syndrome

    autoantibodies

    gangliosides

    neuromuscular transmission
    ...
    immunoglobulines
    Projekt period: from 11.1999 to 10.2001

    98. Disease - Guillain-Barre Syndrome (GBS)
    Disease Name, GuillainBarre syndrome (GBS). SearchTerm, miller-Fischer syndrome,Chronic idiopathic polyneuritis, Relapsing Guillain-Barre syndrome,
    http://disability.ucdavis.edu/resources/diseases/list/disease.asp?id=21

    99. JW Neurology -- Sign In
    Sixty percent of patients with ordinary acute inflammatory demyelinatingpolyneuropathy (AIDP) have had gastrointestinal or respiratory infection within 1
    http://neurology.jwatch.org/cgi/content/full/2001/1206/7

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