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         Metachromatic Leukodystrophy:     more detail
  1. The Official Parent's Sourcebook on Metachromatic Leukodystrophy: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-09-11
  2. Leukodystrophies: Adrenoleukodystrophy, Canavan Disease, Pelizaeus-Merzbacher Disease, Metachromatic Leukodystrophy, Krabbe Disease
  3. Metachromatic leukodystrophy: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Igor, MD, PhD Medica, 2005

1. The Family Village / Library / Leukodystrophy
Resources on Adrenoleukodystrophy, Alexander Disease, Canavan Disease, Krabbes Disease, metachromatic leukodystrophy, and Refsum's Disease.
http://www.familyvillage.wisc.edu/lib_leukodystrophy.html
Leukodystrophy
Types of Leukodystophy: Adrenoleukodystrophy, Alexander Disease, Canavan Disease, Krabbes Disease, Metachromatic Leukodystrophy, and Refsum's Disease
Who to Contact
Where to Go to Chat with Others

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Web Sites
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Search Google for "Leukodystrophy"
Who to Contact
United Leukodystrophy Foundation (ULF)
2304 Highland Drive
Sycamore IL 60718
(815) 895-2432 (fax)
E-mail: ulf@tbcnet.com
Website: http://www.ulf.org/
This is a nonprofit, voluntary health organization dedicated to providing patients and their families with information about their disease. In addition, it provides assistance in identifying sources of medical care, social services, and genetic counseling; establishing a communication network among families; increasing public awareness; acting as an information source for health care providers; and promoting and supporting research into causes, treatments, and prevention of the leukodystrophies. The ULF is supported solely by donations.
Where to Go to Chat with Others
Learn More About It

2. MLD Foundation - Support For Families With Metachromatic Leukodystrophy
Information, support, education and online networking for families throughout the world dealing with metachromatic leukodystrophy (MLD).
http://www.mldfoundation.org

3. EMedicine - Metachromatic Leukodystrophy : Article By Theodore Moore, MD
metachromatic leukodystrophy metachromatic leukodystrophy (MLD) is part of a larger group of lysosomal storage diseases, some of which are progressive,
http://www.emedicine.com/ped/topic2893.htm
(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Genetics And Metabolic Disease
Metachromatic Leukodystrophy
Last Updated: May 26, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: arylsulfatase A deficiency, MLD, neurodegenerative disorders, cerebroside sulfatide, galactosyl sulfatide, bone marrow transplantation, sulfatide sulfatase deficiency, sulfatide accumulation AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography
Author: Theodore Moore, MD , Director, UCLA Pediatric Bone Marrow Transplant Program, Clinical Director, Pediatric Hematology/Oncology; Associate Professor, Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of California at Los Angeles Medical Center Coauthor(s): Robert D Steiner, MD , Head, Division of Metabolism, Associate Professor, Departments of Pediatrics and Molecular and Medical Genetics, Child Development and Rehabilitation Center, Theodore Moore, MD, is a member of the following medical societies:

4. Metachromatic Leukodystrophy Information Page National Institute
metachromatic leukodystrophy information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Metachromatic Leukodystrophy Information Page: National Institute Of Neurologica
metachromatic leukodystrophy information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
http://www.ninds.nih.gov/disorders/metachromatic_leukodystrophy/metachromatic_le
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Email this to a friend or colleague Table of Contents (click to jump to sections) What is Metachromatic Leukodystrophy? Is there any treatment? What is the prognosis? What research is being done? ... Organizations What is Metachromatic Leukodystrophy? Metachromatic leukodystrophy (MLD) is one of a group of genetic disorders called the leukodystrophies. These diseases impair the growth or development of the myelin sheath, the fatty covering that acts as an insulator around nerve fibers. Myelin, which lends its color to the white matter of the brain, is a complex substance made up of at least 10 different enzymes. The leukodystrophies are caused by genetic defects in how myelin produces or metabolizes these enzymes. Each of the leukodystrophies is the result of a defect in the gene that controls one (and only one) of the enzymes. MLD is caused by a deficiency of the enzyme

6. Leukodystrophy Information Page National Institute Of
Specific leukodystrophies include metachromatic leukodystrophy, Krabb disease, adrenoleukodystrophy, PelizaeusMerzbacher disease, Canavan
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. Metachromatic Leukodystrophy
metachromatic leukodystrophy is a genetic disorder caused by a deficiency of the enzyme arylsulfatase A.
http://healthlink.mcw.edu/article/921440824.html
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Metachromatic Leukodystrophy
Metachromatic leukodystrophy (MLD) is a genetic disorder caused by a deficiency of the enzyme arylsulfatase A. It is one of a group of genetic disorders called the leukodystrophies that affect growth of the myelin sheath, the fatty coveringwhich acts as an insulatoron nerve fibers in the brain. There are three forms of MLD: late infantile, juvenile, and adult. In the late infantile form, which is the most common, onset of symptoms begins between ages 6 months and 2 years. The infant is usually normal at birth, but eventually loses previously gained abilities. Symptoms include hypotonia (low muscle tone), speech abnormalities, loss of mental abilities, blindness, rigidity (uncontrolled muscle tightness), convulsions, impaired swallowing, paralysis, and dementia. Symptoms of the juvenile form begin between ages 4 and 14, and include impaired school performance, mental deterioration, ataxia, seizures, and dementia.

8. Natalie's Miracle
Natalie suffers from metachromatic leukodystrophy. This site is about her prayers for healing.
http://onin.com/natalie/
Natalie's Miracle This site is dedicated to the Lord Jesus Christ, the Savior, Healer, and Miracle Worker of the world. The Compassionate Great Physician "Rise up Natalie, I have healed you and made you whole."
Thank you for visiting the Natalie Meadows Fund web site. This site is currently under construction. We invite you to return often. We would appreciate your prayers and support for Natalie. Please e-mail us at natalies_miracle@onin.com or write us at: Barbara Meadows
P.O. Box 681522
Marietta, GA 30068 Visitor
Since 9 June 2001

Updated 2 September 2001

9. Introduction To Leukodystrophy
Krabbe Disease (Globoid Cell Leukodystrophy) metachromatic leukodystrophy (MLD) Neonatal Adrenoleukodystrophy
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. Introduction: Metachromatic Leukodystrophy - WrongDiagnosis.com
Introduction to metachromatic leukodystrophy as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis.
http://www.wrongdiagnosis.com/m/metachromatic_leukodystrophy/intro.htm
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Next sections Basic Summary for Metachromatic Leukodystrophy Prognosis of Metachromatic Leukodystrophy Types of Metachromatic Leukodystrophy Symptoms of Metachromatic Leukodystrophy ... Treatments for Metachromatic Leukodystrophy Next chapters: Microcephaly Miller Fisher Syndrome Monomelic Amyotrophy Motor neuron diseases ... Feedback
Introduction: Metachromatic Leukodystrophy
Metachromatic Leukodystrophy: Brain myelin genetic disorder with various subtypes. Metachromatic Leukodystrophy: Metachromatic leukodystrophy (MLD) is a genetic disorder caused by a deficiency of the enzyme arylsulfatase A. It is one of a group of genetic disorders called the leukodystrophies that affect growth of the myelin sheath, the fatty covering -which acts as an insulator - on nerve fibers in the brain. Researching symptoms of Metachromatic Leukodystrophy: Further information about the symptoms of Metachromatic Leukodystrophy is available including a list of symptoms of Metachromatic Leukodystrophy , or alternatively return to research other symptoms in the symptom center Treatments for Metachromatic Leukodystrophy: Various information is available about treatments available for Metachromatic Leukodystrophy , or research treatments for other diseases.

11. Adam Smith
Artist tells of his fight against metachromatic leukodystrophy, and shares artwork, poetry, beliefs, and photos.
http://www.notthatadamsmith.com/
Home About
Adam Smith
Art Work ... Photos
Welcome to Adam Smith's web site.
Our Lady of Guadalupe
Print by Adam Smith Adam Smith is an artist who works with a variety of media. He also writes poetry and plays trumpet. Adam's art is inspired by the beauty and folk traditions of his home state of New Mexico, his deep religious faith, his love of horses and his Greek heritage. Adam Smith's art can be acquired through VSA Arts of New Mexico , or contact

12. MedlinePlus Medical Encyclopedia Metachromatic Leukodystrophy
metachromatic leukodystrophy Contents of this page Alternative names. Definition. Causes, incidence, and risk factors. Symptoms. Signs and tests
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Symptoms Of Metachromatic Leukodystrophy - WrongDiagnosis.com
Symptoms of metachromatic leukodystrophy including signs, symptoms, incubation period, duration, and correct diagnosis.
http://www.wrongdiagnosis.com/m/metachromatic_leukodystrophy/symptoms.htm
Home Symptoms Diseases Risks ... Metachromatic Leukodystrophy Search our medical database
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Condition Lists

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Current chapter:
Metachromatic Leukodystrophy
Next sections Treatments for Metachromatic Leukodystrophy Articles about Metachromatic Leukodystrophy Glossary for Metachromatic Leukodystrophy Next chapters: Microcephaly Miller Fisher Syndrome Monomelic Amyotrophy Motor neuron diseases ... Feedback
Symptoms of Metachromatic Leukodystrophy
General information about symptoms of Metachromatic Leukodystrophy: The symptom information on this page attempts to provide a list of some possible symptoms of Metachromatic Leukodystrophy. This symptom information has been gathered from various sources, may not be fully accurate, and may not be the full list of symptoms of Metachromatic Leukodystrophy. Furthermore, symptoms of Metachromatic Leukodystrophy may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of symptoms and whether they are indeed symptoms of Metachromatic Leukodystrophy. List of symptoms of Metachromatic Leukodystrophy: The list of symptoms mentioned in various sources for Metachromatic Leukodystrophy includes:

14. NINDS Forwarding Page
A short information sheet compiled by NINDS, the National Institute of Neurological Disorders and Stroke.
http://www.ninds.nih.gov/health_and_medical/disorders/meta_leu_doc.htm
NINDS has redesigned its website and the URL for the page you were seeking has changed. The new URL for this page is /disorders/metachromatic_leukodystrophy/metachromatic_leukodystrophy.htm . Please update your bookmark to this page. You will be automatically taken to this page in 5 seconds, or you can click the link to go there now.

15. Metachromatic Leukodystrophy
a CHORUS notecard document about metachromatic leukodystrophy
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Introduction To Leukodystrophy
metachromatic leukodystrophy (MLD). DEFINITION The Metachromatic Leukodystrophies (MLD) are a group of degenerative white matter diseases.
http://www.ulf.org/ulf/intro/
U NITED L EUKODYSTROPHY F OUNDATION
2304 Highland Drive Sycamore, Illinois 60178 Phone: (800) 728-5483 FAX: (815) 895-2432
Introduction to Leukodystrophy
Outlined below are brief introductions to the leukodystrophies. Further extensive in-depth research information is available on these subjects and more through the ULF library of printed and videotape materials. When requesting further information please let us know whether you are a professional or lay-person so that we can respond with the appropriate information level.
Introduction
Patterns of Inheritance
Adrenoleukodystrophy (ALD)/Adrenomyeloneuropathy (AMN)
Aicardi-Goutieres Syndrome ...
Zellweger Syndrome INTRODUCTION The leukodystrophies are genetically determined progressive disorders that affect the brain, spinal cord and peripheral nerves. The term leukodystrophy derives from the Greek words "leuko" meaning white and referring to the white matter of the nervous system and "dystrophy" meaning imperfect growth or development. White matter is white to the naked eye because it contains a complex chemical substance called the myelin sheath. Myelin contains a variety of fatty substances or lipids. Its function is to insulate the axon through which nerve impulses are conducted, much as does insulation around an electric wire; the axon being the biological equivalent of the wire. The myelin sheath is a very complex substance. It is made up of at least ten, and probably more distinct chemicals. Each of the leukodystrophies affects one (and only one) of these substances that all affect the myelin sheath in some way, but otherwise, they are totally separate. Leukodystrophy of one type, does not in any way predispose to, or increase the risk of another type of leukodystrophy.

17. The Stennis Foundation
Raising public awareness regarding metachromatic leukodystrophy, and raising funds for MLD research.
http://www.stennisfoundation.org
The Stennis Foundation for MLD Online PO Box 30065 Amarillo, TX 79120 Welcome Contact Info E-Mail Upcoming Events ... Special Fundraiser The Stennis Foundation is recognized by the IRS as a tax-exempt charitable organization under section 501(c)3. We need your gifts, large or small, to help us forcefully advance toward a cure for MLD. Donate online by clicking on the "Make a Donation" button or send your gifts to The Stennis Foundation P O Box 30065 Amarillo, TX 79120. Your support is appreciated!
Here at The Stennis Foundation We're diligently working so that 2005 Is when MLD will no longer thrive! "One Step Closer" Walk for Leukodystrophy in Paris, TN! Honoring Tucker Wells October 1, 2005 Registration/sign in 7:30 a.m. Walk begins at 8:30 a.m. Memorial Park $10 registration includes T-shirt. Follow these links to: Submit your online registration and fee for the Walk Print your Pledge Sheet Print your Release Form Learn more about The Stennis Foundation Navy "One Step Closer to a Cure"

18. Leukodystrophy
Specific diseases adrenoleukodystrophy metachromatic leukodystrophy spongy degeneration (Canavan) globoid cell (Krabbe) leukodystrophy
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. MLD Foundation - Support For Families With Metachromatic
Information, support, education and online networking for families throughout the world dealing with metachromatic leukodystrophy (MLD).
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

20. National Tay-Sachs Allied Diseases Association
An organization offering support and programs geared to families affected by TaySachs Disease and over 40 other fatal degenerative genetic
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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