21. The Molecular Genetics Of Marfan Syndrome And Related Keywords marfan syndrome; fibrillin; microfibrillopathies 2000 by J Med Genet This article has been cited by other articles http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

22. EMedicine - Marfan Syndrome : Article By Harold Chen, MD, MS, FAAP, FACMG marfan syndrome marfan syndrome is an inherited connective tissue disorder transmitted as an autosomal dominant trait. It is noteworthy for its worldwide http://www.emedicine.com/ped/topic1372.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Genetics And Metabolic Disease Marfan Syndrome Last Updated: May 14, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: Marfan's syndrome, Marfan disease, Marfan's disease AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Harold Chen, MD, MS, FAAP, FACMG , Chief, Professor, Department of Pediatrics, Section of Perinatal Genetics, Louisiana State University Medical Center Harold Chen, MD, MS, FAAP, FACMG, is a member of the following medical societies: American Academy of Pediatrics American College of Medical Genetics American Medical Association American Society of Human Genetics , and Teratology Society Editor(s): James Bowman, MD , Senior Scholar of Maclean Center for Clinical Medical Ethics, Professor Emeritus, Department of Pathology, University of Chicago; Robert Konop, PharmD

23. Lakers' Draft Pick Faces Heart Surgery and Marfan's syndrome, which often leads to a weakening of heart valves. When a person overexerts, those conditions can be fatal. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

24. EMedicine - Marfan Syndrome : Article By Khalid Channell, MD marfan syndrome marfan syndrome (MFS) is a spectrum disorder caused by a heritable genetic defect of connective tissue that has an autosomal dominant mode http://www.emedicine.com/orthoped/topic414.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Orthopedic Surgery Pediatrics Marfan Syndrome Last Updated: October 5, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: MFS, Marfan's syndrome, arachnodactyly, long and thin digits, dolichostenomelia, long limbs, pectus deformities, pectus excavatum, pectus carinatum, thoracolumbar scoliosis, aortic dilation, aortic regurgitation, aneurysm, mitral valve prolapse, myopia, cataracts, retinal detachment, superior lens dislocation AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Indications Relevant Anatomy And Contraindications ... Bibliography Author: Khalid Channell, MD , Staff Physician, Department of General Surgery, Division of Orthopedic Surgery, King Drew Medical Center Coauthor(s): Eleby R Washington III, MD, FACS , Associate Professor, Department of Surgery, Division of Orthopedics, Charles R Drew University of Medicine and Science Editor(s): Charles T Mehlman, DO, MPH

25. A Forum For Worldwide Communication For Marfan Syndrome A global information center providing links to marfan syndrome Organizations aroud the world http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

26. Medical References: Marfan Syndrome marfan syndrome affects about 1 in 5000 Americans. It is one of the most common inherited disorders of connective tissue. It can affect the heart, http://www.marchofdimes.com/professionals/681_1216.asp

View All Chapters Find Your Local Chapter September 9, 2005 Select one Folic Acid Pregnancy Prenatal Screening Infections/Diseases Loss Concerns Newborn Information Birth Defects Polio Genetics Research Funding Perinatal Statistics Medical References Continuing Education ... Prematurity Quick Reference and Fact Sheets Marfan Syndrome Marfan syndrome is an inherited connective tissue disorder that can affect the heart, blood vessels, lungs, eyes, bones and ligaments. Symptoms of Marfan syndrome may be mild or severe, and may be present at birth or appear in childhood or in adult life. Marfan syndrome affects about 1 in 5,000 Americans. It is one of the most common of the more than 100 inherited disorders of connective tissue (material that holds tissues of the body together). The disorder affects males and females from all racial and ethnic groups. It is named for Dr. Antoine Marfan who, in 1896, described a 5-year-old patient with unusually long, slender fingers and limbs and other skeletal abnormalities. How are individuals with Marfan syndrome affected? Affected individuals often are tall, slender and loose-jointed. Arms and legs may be unusually long in proportion to the torso. Feet often are flat. The spine may be curved (scoliosis), and the breastbone may protrude or look caved in. The face may be long and narrow, with a high roof of the mouth and crowded teeth.

27. Marfan Syndrome : Canadian Marfan Association Home Page Information, articles, events, a patient survey, and products. Also contains an article on Pharaoh Akhenaten who was believe to have the disease. http://www.marfan.ca/

... dedicated to preventing the early death and disability, and improve the quality of life for Marfan patients in Canada, through comprehensive programs of... Education... Support... Research... Marfan syndrome is a genetic disorder of the connective tissue that can affect the skeletal system, eyes, lungs, blood vessels and heart. About Marfan Syndrome Become a Member About the Association Products ... Research Grant Proposals NEW! Medical Advisory Board Hbc Rewards Community Program National and Regional Events CMA Brochures Order Form ... Contact Us Call for Grant Proposals The Canadian Marfan Association is requesting applications for a one year grant for clinical or basic research on the Marfan syndrome. Click here for details If you wish to contact us, please do so using any of the following methods: Canadian Marfan Association Centre Plaza Postal Outlet 128 Queen St. South P.O. Box 42257 Mississauga, Ontario, L5M 4Z0, Canada

28. Marfan Syndrome Online interactive user community. http://www.marfansyndrome.us/

29. Marfan Syndrome Fact Sheet marfan syndrome is an inherited disorder of the connective tissues which affects many In marfan syndrome, the connective tissue in the heart, lungs, http://www.marfan.ca/syndrome.htm

info@marfan.ca http://www.marfan.ca Toll Free #: 1-866-722-1722 Tel: (905) 826-3223 Fax: (905) 826-2125 What is Marfan Syndrome? Marfan Syndrome is an inherited disorder of the connective tissues which affects many organ systems, including the skeleton, lungs, eyes, heart and blood vessels. The condition, first described by Dr. Marfan in 1896, can affect both men and women of any race or ethnic origin. Connective tissue "connects", provides structural support, and determines the elasticity of the body's organs, bones, and ligaments. In Marfan Syndrome, the connective tissue in the heart, lungs, eyes and skeletal systems can stretch and weaken. What Causes Marfan Syndrome? It is now known that a single abnormal gene located on chromosome 15 and containing the coding for fibrilin , a connective tissue protein, is responsible for the syndrome. Most of the time this gene is inherited from a parent who is affected. About 30% of cases occur when the abnormal gene arises in an egg or a sperm of an unaffected parent. Each child of a Marfan sufferer has a 50-50 chance of inheriting the syndrome. Since genes carry the master plan for all human characteristics, an abnormality of one gene, such as the Marfan gene, results in a specific pattern of bodily changes and medical problems. Marfan Syndrome is inherited as an "autosomal dominant" condition. One in ten affected children are seriously affected.

30. Marfan Syndrome - Health And Medical Information Produced By Doctors - MedicineN Doctorproduced health and medical information written for you to make informed decisions about your health concerns. http://www.medicinenet.com/marfan_syndrome/article.htm

document.writeln(''); MedicineNet Home > Marfan Syndrome search help Printer-Friendly Format FREE Newsletters Email to a Friend ... Next Marfan Syndrome What is Marfan syndrome? How common is Marfan syndrome? What are the characteristics of Marfan syndrome? What causes Marfan syndrome? ... Marfan Syndrome At A Glance What is Marfan syndrome? Marfan syndrome is an inherited condition that affects the connective tissue. The primary purpose of connective tissue is to hold the body together and provide a framework for growth and development. In Marfan syndrome, the connective tissue is defective. Because connective tissue is found throughout the body, Marfan syndrome can affect many body systems, including the skeleton, eyes, heart and blood vessels, nervous system, skin, and lungs. How common is Marfan syndrome? Marfan syndrome affects men, women, and children, and has been found among people of all races and ethnic backgrounds. It is estimated that at least 25,000 people in the United States have the disease. Marfan Syndrome Center Next Next: What are the characteristics of Marfan syndrome? >>

31. Arthritis - UW Medicine - Department Of Orthopaedics And Sports Medicine What the disease is and includes the impacts on daily life. http://www.orthop.washington.edu/arthritis/types/marfan/01

Home Site Map Contact Us Links ... Arthritis The Arthritis Source Our articles (listed to the left) feature information about managing arthritis, medications for arthritis, more than 20 types of arthritic conditions, and more. All articles were written or edited by our medical faculty . Some of them were developed with help from the Arthritis Foundation If you have specific questions about arthritis, you might want to search our site by typing in your question. On our search page , you can also search for a doctor or surgeon. The Department of Orthopaedics and Sports Medicine The UW Medicine Bone and Joint Surgery Center and the UW Medicine Eastside Specialty Center offer subspecialized surgical care for arthritis patients. UW surgeons provide the most current approaches for patients with arthritis affecting: The hips and knees The shoulders and elbows The neck and back The wrists and hands ... The feet and ankles UW Rheumatoid Arthritis Service The UW Medicine Bone and Joint Surgery Center at UWMC-Roosevelt offers a specialty program for rheumatoid arthritis. The

32. Stanford University Marfan Center marfan syndrome was initially described in 1896 and is now recognized as Staff of the Center for marfan syndrome and Related Connective Tissue Disorders http://marfan.stanford.edu/

Stanford University Center for Marfan Syndrome History and Mission The Stanford University Marfan Clinic was established in 1988 by Dr. D. Craig Miller at the urging of the local chapter of the National Marfan Foundation based upon the perceived need to establish a specialized care center in the western United States. At the fifth anniversary, the name was changed to the Stanford University Center for Marfan Syndrome and Related Connective Tissue Disorders to reflect the broader mission of the Center. Marfan syndrome was initially described in 1896 and is now recognized as a genetic disorder of connective tissue that affects the bones, joints, eyes, blood vessels and the heart. Recent studies in molecular genetics have identified the fibrillin gene product as the defective connective tissue protein that causes Marfan syndrome. Marfan syndrome affects approximately 1 per 5,000 individuals throughout the world including both genders as well as all races and ethnic groups. Prior to innovations in the medical and surgical management of this disease, most patients died of cardiovascular complications by the age of 50. The central mission of the Stanford University Center for Marfan Syndrome and Related Connective Tissue Disorders is to be an integrated, multi-disciplinary unit that provides comprehensive, cost-effective, state-of-the-art diagnostic evaluation and care for adult and

33. Health And Medical Information Produced By Doctors - MedicineNet.com A QuestionAnswer format page of information. http://www.medicinenet.com/Script/Main/Art.asp?li=MNI&ag=Y&ArticleKey=41

34. Marfan Syndrome: The Similarities To Copper Deficiency Reviews the similarities between copper deficiency and marfan syndrome including aortic aneurysms and emphysema. http://www.ctds.info/marfan_syndrome.html

Con nective Tissue Disorder Home Search Site Map ... Links Marfan Syndrome The Links to Copper Deficiency Read my Contents: Features Common to Both Marfan Syndrome and Copper Deficiency Indications That Marfan Syndrome May Be Affected by Nutrition Lung Disorders, Emphysema, Elastin, Desmosines and Nutrition Aneurysms, Elastin, Desmosines and Nutrition Features Common to Both Marfan Syndrome and Copper Deficiencies C opper is a trace mineral found in all body tissues. It is vital in making elastin, a chief component of the elastic muscle fibers found throughout the body, especially in the heart and lungs. It is needed to build strong bones, connective tissue and joints. Copper is needed for the proper function of the enzyme lysyl oxidase, which is required in the crosslinking of collagen and elastin. A significant portion of the symptoms of Marfan syndrome, and to a lesser extent some the other inherited connective tissue disorders, are identical to symptoms of copper deficiency. Geneticists believe that Marfan syndrome is caused solely by a genetic defect. But is it? Just because a disorder is inherited does not automatically exclude nutrition from playing a role in the manifestations of its symptoms.

35. Marfan Syndrome - Wikipedia, The Free Encyclopedia marfan syndrome is a connective tissue disorder, affecting many structures marfan syndrome is an autosomal dominant disorder that has been linked to the http://en.wikipedia.org/wiki/Marfan_syndrome

Wikimedia needs your help in the final day of its fund drive. See our fundraising page Over US$240,000 has been donated since the drive began on 19 August. Thank you for your generosity! Marfan syndrome From Wikipedia, the free encyclopedia. Marfan syndrome is a connective tissue disorder characterized by unusually long limbs . The disease also affects other bodily structures—including the skeleton lungs eyes heart and blood vessels —in less obvious ways. It is named for Antoine Marfan , the French pediatrician who first described it in Contents Genetics Symptoms Treatment Affected persons ... edit Genetics Marfan syndrome is an autosomal dominant disorder that has been linked to the FBN1 gene on chromosome codes for a protein called fibrillin , which is essential for the formation of elastic fibres found in connective tissue. Marfan syndrome is associated with incomplete penetrance, therefore not all persons carrying the mutation develop the disease. Without the structural support provided by fibrillin, many connective tissues are weakened, which can have severe consequences on support and stability. A related disease has been found in mice , and it is hoped that the study of mouse fibrillin synthesis and secretion, and connective tissue formation, will further our understanding of Marfan syndrome in humans.

36. THE MERCK MANUAL--SECOND HOME EDITION, Marfan Syndrome In Ch. 279, Hereditary Co marfan syndrome is a rare disorder of connective tissue, resulting in In marfan syndrome, which is caused by a dominant gene, some fibers and other http://www.merck.com/mmhe/sec23/ch279/ch279c.html

var externalLinkWarning = "The link you have selected will take you to a site outside Merck and The Merck Manuals.*n*nThe Merck Manuals do not review or control the content of any non-Merck site. The Merck Manuals do not endorse and are not responsible for the accuracy, content, practices, or standards of any non-Merck sources."; Search The Second Home Edition , Online Version Search Index A B C D ... Z Sections Accidents and Injuries Blood Disorders Bone, Joint, and Muscle Disorders Brain, Spinal Cord, and Nerve Disorders ... Women's Health Issues Resources Anatomical Drawings Multimedia Pronunciations Weights and Measures ... , Online Version Section Children's Health Issues Chapter Hereditary Connective Tissue Disorders Topics Introduction Chondrodysplasias Cutis Laxa Ehlers-Danlos Syndrome Marfan Syndrome Mucopolysaccharidoses Osteogenesis Imperfecta Osteopetroses Pseudoxanthoma Elasticum Marfan Syndrome Buy The Book Print This Topic Email This Topic Pronunciations aneurysm aorta aortic dissection echocardiography ... retina Marfan syndrome is a rare disorder of connective tissue, resulting in abnormalities of the eyes, bones, heart, and blood vessels. In Marfan syndrome, which is caused by a dominant gene, some fibers and other parts of connective tissue undergo changes that ultimately weaken the tissue. The weakening affects bones and joints as well as internal structures, such as the heart, blood vessels, eyes, and intestines. Weakened tissues stretch, distort, and can even tear. For example, the aorta may weaken, bulge, or tear. Connective tissues that join structures may weaken or break, separating formerly attached structures. For example, the eye's lens or retina may separate from its normal attachments.

37. Marfan Syndrome a CHORUS notecard document about marfan syndrome. lens subluxation. Cf homocystinuria. More info marfan syndrome OMIM http://chorus.rad.mcw.edu/doc/00246.html

CHORUS Collaborative Hypertext of Radiology Musculoskeletal system About CHORUS Search Feedback Marfan syndrome connective-tissue disorder: autosomal dominant, 15% sporadic cardiovascular system (prob. cause of death in 93%) aortic aneurysm (mostly ascending) dilatation of aortic sinuses aortic dissection coarctation musculoskeletal system tall stature, long limbs arachnodactyly lax joints spine scoliosis (60%) / kyphosis / pectus dural ectasia eye lens subluxation Cf: homocystinuria More info: Marfan syndrome [OMIM] Charles E. Kahn, Jr., MD - 24 November 1995 Last updated 26 May 2004 Related CHORUS documents: arachnodactyly aortic aneurysm homocystinuria aortic dissection: etiology ... progeria (Hutchinson-Gilford) syndrome Search for related articles: AJR American Journal of Roentgenology PubMed : index to biomedical literature ... Medical College of Wisconsin

38. EMedicine - Marfan Syndrome : Article By Harold Chen, MD, MS, FAAP, FACMG Article from eMedicine. http://www.emedicine.com/PED/topic1372.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Genetics And Metabolic Disease Marfan Syndrome Last Updated: May 14, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: Marfan's syndrome, Marfan disease, Marfan's disease AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Harold Chen, MD, MS, FAAP, FACMG , Chief, Professor, Department of Pediatrics, Section of Perinatal Genetics, Louisiana State University Medical Center Harold Chen, MD, MS, FAAP, FACMG, is a member of the following medical societies: American Academy of Pediatrics American College of Medical Genetics American Medical Association American Society of Human Genetics , and Teratology Society Editor(s): James Bowman, MD , Senior Scholar of Maclean Center for Clinical Medical Ethics, Professor Emeritus, Department of Pathology, University of Chicago; Robert Konop, PharmD

39. What Is The Marfan Syndrome The marfan syndrome is a heritable disorder of the connective tissue that The most serious problems associated with the marfan syndrome involve the http://www.marfanworld.org/whatisthemarfansyndrome.htm

International Federation of Marfan Syndrome Organizations What is the Marfan Syndrome? The Marfan syndrome is a heritable disorder of the connective tissue that affects many organ systems, including the skeleton, lungs, eyes, heart and blood vessels. The condition affects both men and women of any race or ethnic group. It is estimated that at least 200,000 people in the United States have the Marfan syndrome or a related connective tissue disorder. What medical problems are associated with the Marfan syndrome? The Cardiovascular System The most serious problems associated with the Marfan syndrome involve the cardiovas­cular system. The two leaflets of the mitral valve may billow backwards when the heart contracts (mitral valve prolapse). This can lead to leakage of the mitral valve or irregular heart rhythm. In addition, the aorta, the main artery carrying blood away from the heart, is generally wider and more fragile in patients with the Marfan syndrome. This widening is progressive and can cause leakage of the aortic valve or tears (dissection) in the aorta wall. When the aorta becomes greatly widened, or tears, surgical repair is necessary. • The Skeleton Skeletal manifestations common in people with the Marfan syndrome include curvature of the spine (scoliosis), abnormally shaped chest (pectus deformity), loose jointedness and dispropor-tionate growth usually, but not always, resulting in tall stature.

40. Marfan Syndrome A young man with marfan syndrome, showing characteristically long limbs and narrow face. Arachnodactyly in an 8year-old girl with marfan syndrome. http://medgen.genetics.utah.edu/photographs/pages/marfan_syndrome.htm

Marfan Syndrome view 613 KB version view 3 KB version A young man with Marfan syndrome, showing characteristically long limbs and narrow face. view 369 KB version view 5 KB version Arachnodactyly in an 8-year-old girl with Marfan syndrome. The hand at the left is that of a young woman with Marfan's syndrome, while the hand at the right is a normal male. Both persons were of the same height, 188 cm. However, note that the hand at the left demonstrates arachnodactyly. This mucin stain of the wall of the aorta demonstrates cystic medial necrosis, typical for Marfan's syndrome and causes the connective tissue weakness that explains the aortic dissection. Pink elastic fibers, instead of running in parallel arrays, are disrupted by pools of blue mucinous ground substance. This view of the mitral valve in a patient with Marfan's syndrome depicts a floppy mitral valve. The leaflet on the lower left has ballooned upward and the prolapse has resulted in contusion of the top of the leaflet, with a red black area of discoloration. Examinations Photographs Movies Links ... noJava Home

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 2     21-40 of 125    Back | 1  | 2  | 3  | 4  | 5  | 6  | 7  | Next 20