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         Madelungs Disease:     more detail

1. EMedicine - Tumescent Liposuction Article By Ron Shelton, MD
Discusses the use of liposuction in the palliative treatment of Madelung's Disease. The tumescent method is the safest method found to date.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

2. Lipoma Forum Index
Dercum's Disease The section is for the disussion of Dercum's Disease (Adiposis Dolorosa), a disease in the lipoma family.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

3. About Madelung's Disease
pesticides and Madelung's Disease. More on this when results of this research are published. NEW Read some new ideas about Madelungs 1
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. BenignMisused
my enthusiasm for a medical study concluding that madelungs disease is notbenign, harmful ALL of these apply to many cases of Madelung s disease,
http://www.geocities.com/madelungs/BenignMisused.html
Misusing "Benign" Updated 12/29/2003 People lacking first hand experience with this condition will be a little taken aback at my enthusiasm for a medical study concluding that Madelungs Disease is not benign, but while doctors in North America could find evidence that it was benign they have allowed patients to slowly grow worse and die with little or no attempt to intervene.
After following 30 patients with this condition for 30 years, an article published in the International Journal of Obesity in February, 2002 concludes:
"...our long term study firstly demonstrated that MSL is associated with a significant morbidity and mortality. Both morbidity and mortality should be considered as disease-specific... Therefore, we believe that the definition 'benign symmetrical lipomatosis' still adopted by several authors can no longer be justified"
The abstract for this article can be found HERE
and the full text article can be purchased through the same site.
The first step in solving any problem is admitting that the problem exists, finally we have data saying that we are facing a kind of terminal illness that nobody really understands. Apparently it took 3500 years to achieve this step. Hopefully the subsequent steps won't take as long.
According the the 18th Edition of Taber's Cyclopedic Medical Dictionary, BENIGN means

5. Madelung's Disease Benign Symmetric Lipomatosis
Madelung's disease or Benign Symmetric Lipomatosis is a _QUOTATION_sight diagnosis._QUOTATION_ Only a doctor knowledgeable about the disease can
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. Pathology Teaching Slide - Soft Tissue Pathology
The first dozen or so entries are images of Madelung's Disease, taken with various scanning techniques.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. NEJM Madelung's Disease Inherited From An Ancient Mediterranean
Images in Clinical Medicine from The New England Journal of Medicine Madelung's Disease Inherited from an Ancient Mediterranean Population? Only
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. OMIM Entry 151800
Describes the form of Multiple Symmetric Lipomatosis (MSL) characterized by a collar of fat around the neck. The article suggests the cause to be a
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. BSL
BRODIE's DISEASEMADELUNGS FETTHALS-LAUNOIS BENSAUDE's LIPOMATOSIS-MSL LIPOMATOSI SIMMETRICA BENIGNA Prof. Camillo O. DI CICCO Member of " DNA
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. Radial Aplasia And Distraction
for radial dysgenesis or limb shortness from primary disease processes such or Madelungs's deformity can be more easily and carefully
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. Directory Home Ventures
madelungs disease. Home Health Conditions and Diseases Nutrition andMetabolism Disorders madelungs disease. CATEGORIES. LINKS
http://www.resourcenet.org.uk/Health/Conditions_and_Diseases/Nutrition_and_Metab

12. Dyschondrosteosis And Madelung Wrist Deformity ( 2001 )
I'm now 147 cm), I was then preliminary diagnosed with this disease. be very interested in talking to other people who have Madelungs and
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Nutrition And Metabolism Disorders Ventures
Glycogen Storage Disease Type I (0). madelungs disease (0). Malnutrition (0).Obesity (0). Organizations (0). Porphyrias (0). Vitamins and Minerals (0)
http://www.resourcenet.org.uk/Health/Conditions_and_Diseases/Nutrition_and_Metab

14. M - Medical Conditions
madelungs disease Benign Symmetric Lipomatosis, madelungs disease or BenignSymmetric Lipomatosis is a quotsight diagnosis. Only a doctor knowledgeable
http://conditions.webdirs.net/medgroup-M.html
Directory M : 1243 page(s) Part : 1 M. D. Anderson Cancer Center Information and resources on a number of tumors from this comprehensive cancer treatment facility affiliated with the University of Texas. Located in Houston. M. D. Anderson Cancer Center Information about researchers studying the genetic components of alopecia areata. Offers disease information and study details. M. D. Anderson Cancer Center Prevention Oriented to research, clinical service and educational programs. Located in Houston, Texas. M. D. Anderson Cancer Center Thyroid Cancer Presents research, symptoms, treatments, and clinical trials. Includes news, a support group and message board. M. D. Anderson Cancer Center Lung Cancer Provides access to information about prevention, symptoms, diagnosis, treatment, clinical trials and stories of survivors. M. D. Anderson Cancer Center Melanoma A discussion of the topic from this Houston, Texas institution. M. D. Anderson Cancer Center Prostate Cancer Message Board Share information and experiences with other patients via this online discussion format. M.D. Anderson Bladder Cancer

15. N - Medical Conditions
NEJM madelungs disease Inherited from an Ancient Mediterranean Population,Images in Clinical Medicine from The New England Journal of Medicine Madelungs
http://conditions.webdirs.net/medgroup-N-5.html
Directory N : 832 page(s) Part : NEJM Madelungs Disease Inherited from an Ancient Mediterranean Population Images in Clinical Medicine from The New England Journal of Medicine Madelungs Disease Inherited from an Ancient Mediterranean Population Only the first part of the article is displayed. You will have to purchase the article if you want to see it. Nemaline Myopathy Information and contacts regarding Nemaline Myopathy Neon Nits Offers locator spray, shampoo, and removal kits. Neonatal Cystic Fibrosis Screening Information sheets on testing for immunoreactive trypsinogen to diagnose CF in infants. Test description, preparation, risks, expectations, special considerations, normal and abnormal values, and evaluation of results. Neoplasia International journal oriented to basic cancer research and published by the Nature Publishing Group. Neoplasm Paediatric Brain Tumours British site with information about paediatric brain tumours. Neoplasms Karolinska Institutet List of links relating to neoplasms, with special section on nervoussystem neoplasms. From Sweden. Neoral Pregnancy Registry for Psoriasis and Rheumatoid Arthritis A research study conducted by Thomas Jefferson University, on the effects of Neoral during pregnancy.

16. ¬d¸ß¿é¥X
We describe two cases of madelungs disease both patients presented complainingof a development of a painless neck mass that was increasing in size.
http://kjms.kmu.edu.tw/cgi-bin/kjms?VOL=&PAGENUM=133-136

17. Conditions And Disorders
Browse through our hand selected links to find Madelung s Disease photos and images. Save up to 80% off retail store prices on your Photo madelungs disease.
http://www.profound-health.com/ConditionsandDisorders/NutritionalDisorders/Madel
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18. Conditions And Disorders
Browse through our hand selected links to find Madelung s Disease magazines. Magazine madelungs disease Medical Information Site
http://www.profound-health.com/ConditionsandDisorders/NutritionalDisorders/Madel
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19. SF AIDS Fdn: BETA Summer 2000 -- The Wide-Ranging Effects Of Nucleoside Analogs
HAARTassociated lipodystrophy and a form of multiple symmetricallipomatosis (abnormal fat accumulations), also known as MSL or madelungs disease.
http://www.sfaf.org/treatment/beta/b44/b44toxicity.html
Published in the Bulletin of Experimental Treatments for AIDS Summer 2000 issue, by the San Francisco AIDS Foundation.
Summer 2000 Table of Contents

Main Page

beta@sfaf.org
The Wide-Ranging Effects Of Nucleoside Analogs
A Look at Mitochondrial Toxicity
Dave Gilden September 25, 1999: A group of French doctors report on five cases of a rare syndrome of cerebral, neurologic, and/or retinal damage in 8 of 2,000 babies born to HIV positive mothers. This large mother-child cohort had received AZT (Retrovir) or AZT/3TC (Epivir) to prevent HIV transmission during pregnancy and delivery. The babies also displayed a variety of other abnormalities in muscle, heart, pancreas, and bone marrow activity. Underlying defects in energy production also were apparent. Two of the babies died after about a year. All were HIV negative. October 14, 1999: U.S. Bioscience announces the termination of a trial of their experimental nucleoside analog or nucleoside reverse transcriptase inhibitor (NRTI) lodenosine because of "serious adverse events." On October 11, one of the trial participants died due to a striking liver failure syndrome that continued to worsen for a month after he had stopped taking lodenosine. Three similar deaths occurred in the seven weeks after the remaining trial participants were taken off lodenosine. Another nine persons had to be hospitalized for monitoring and treatment. In all, 75 trial participants exhibited some sign of liver damage in blood tests.

20. Adipose Tissue Metabolism In Benign Symmetric Lipomatosis -- Nielsen Et Al. 86 (
Initially described a century ago (1, 2) under the eponyms LaunoisBensaudesyndrome and madelungs disease, the syndromes are today termed BSL and at least
http://jcem.endojournals.org/cgi/content/full/86/6/2717

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Other Original Studies
Adipose Tissue Metabolism in Benign Symmetric Lipomatosis
James Levine Ricky Clay and Michael D. Jensen Endocrine Research Unit and Department of Plastic Surgery (R.C.), Mayo Clinic, Rochester, Minnesota 55905 Address all correspondence and requests for reprints to: Michael D. Jensen, M.D., Endocrine Research Unit, 5-194 Joseph, Mayo Clinic, Rochester, Minnesota 55905. E-mail: Abstract Type 2 benign symmetric lipomatosis (BSL) is characterized by abnormal growth of adipose tissue in the upper back, deltoid region, upper arms, hips, and upper thigh region. Studies of lipomatous tissue in vitro have suggested that defective lipolysis may account for excess fat accumulation; however

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