141. Science News Online - This Week - News Feature - 10/4/97 The cause of mad cow disease and of the new human CJD variant has been difficult to Human version of mad cow disease? Science News 149(April 13)228. http://www.sciencenews.org/sn_arc97/10_4_97/fob1.htm

October 4, 1997 Mad Cow Disease, Human Illness Tied by N. Seppa T wo groups of researchers have tightened the link between mad cow disease and a devastating brain disorder that has stricken 21 people in the United Kingdom in the past 3 years. Those people apparently ate infected beef. The human illness, a variant of Creutzfeldt-Jakob disease (CJD), causes brain damage, dementia, tremors, and death. The mysterious agent behind this disease riddles the brain with tiny holes, a condition called spongiform encephalopathy (SN: 10/12/96, p. 238). In the new studies, the researchers injected brain tissue from infected cows into a group of mice. Other mice received tissue from people who had died of variant CJD. Less than a year after the injections, both groups of mice displayed the same bizarre symptoms, such as walking backward. The disease ultimately proved fatal, as it has in humans and cows. The two studies, both published in the Oct. 2 Nature, "confirm the notion that the variant CJD is very similar to BSE," or bovine spongiform encephalopathy, says Blas Frangione, a pathologist at New York University. Classical CJD, first described in 1920, is a rare disease of unknown origin that strikes about 1 in 1 million elderly people. The recent variant, however, attacks people of any age.

142. John Titor - Mad Cow Mad cowtype disease blamed on transfusion USA Today August 8, 2004 A second case in which the human form of mad cow disease was spread through a blood http://www.johntitor.com/Pages/MadCow.html

MAD COW DISEASE John Titor Story Site News Worldline 2036 Time Travel ... Original Titor Info John's Posts about Mad Cow Disease News about Mad Cow Disease on this Worldline PAGE CURRENTLY UNDER CONSTRUCTION MORE MAD COW NEWS Feds looked into human mad cow cases in NY WASHINGTON, Oct. 29 (UPI) Federal officials have investigated 20 cases for possible human mad cow disease in the last 10 years in New York, where state officials currently are looking into a cluster of five cases of a related disease, United Press International has learned. Five cases of what initially appeared to be a fatal, incurable brain illness known as Creutzfeldt Jakob disease recently have been reported in Ulster county and surrounding areas in southern New York. "I believe there's definitely a problem in this area," said Brent Tobey, who lives in Ulster county and whose father, Richard Tobey, 59, died earlier this month after being diagnosed with CJD.

143. MadCowQuest mad cow disease is a fatal brain illness with unusually long incubation periods measured in months to years, and is caused by an unconventional http://www.interactworks.info/madcow/madcowquest.htm

A WebQuest for students in Public Health Disciplines Mad Cow Disease is a fatal brain illness with unusually long incubation periods measured in months to years, and is caused by an unconventional transmissible agent. Designed by Leo M. Grassi solve@interactworks.info

144. Mad Cow Disease mad cow disease, also known as BSE, is a minor cattle epidemic that has devastated cattle businesses in Europe. The disease, which produces holes in the http://library.thinkquest.org/11170/epidemics/madcow.html

Mad Cow Disease, also known as [ BSE ], is a minor cattle epidemic that has devastated cattle businesses in Europe. The disease, which produces holes in the brain, was first reported in 1986 in Great Britain and has also been reported in France, Ireland, Switzerland, and Portugal. BSE is usually only found in cattle, although it is assumed that BSE can cause CJD. See Human Victims below BSE is caused by waste included in the cattles' feed to increase their milk supply. Some of the waste, or offals (brain, spleen, thymus, tonsil, and gut), could contain tissues from sheep infected with Scrapie, a related disease. Scrapie is a fatal brain disease found in some sheep. The name "Scrapie" refers to the furious scraping of itching developed in the sheep. The UK paid compensation to British farmers for the cattle they lost. Though the compensation for each cow was only worth half a cow, the total had reached $74.4 million. The first symptom of BSE is a progressive degeneration of the nervous system. Infected cattle may:

145. Technology News: Health : Plasmas Destroy Mad Cow Disease Particles Everything you need to know about doing business on the Internet. Information for CLevel executives and small-to-mid-sized business managers. http://www.technewsworld.com/story/45200.html

E-BUSINESS TECHNOLOGY CRM LINUX ... Reviews Reader Services Account Management Become an Affiliate Discussion ECT News Network Map ... RSS / Headline Feeds Search ECT News Network WiFi Hotspot Locator [NEW] September 9, 2005 03:03:58 AM PDT TechNewsWorld Science HEALTH AND MEDICINE Plasmas Destroy Mad Cow Disease Particles E-Mail Article Print Version The Herald 08/03/05 6:00 PM PT The technique involves using forms of gas called plasmas to strip the contaminating material from stainless steel surfaces. Radio waves excite the molecules of harmless gases, which then scour the surface of the instruments, breaking down traces of biological tissue and converting them to non-toxic gases. Free WiFi Hotspot Locator from TechNewsWorld Wondering where to find the nearest publicly available WiFi Internet access? Our global directory of 70,000 locations in 26 countries is a terrific tool for mobile computer users. Scientists at Edinburgh University have developed a new hospital cleaning method that could stop the spread of the human form of mad cow disease. Prions, infectious particles that cause the condition, linked to Creutzfeldt-Jakob Disease (CJD), are immune to most sterilization processes.

146. Mad Cow Disease And Beef Trade: An Update mad cow disease and beef trade An update encephalopathy (BSE), or mad cow disease, on May 20, 2003, dealt a body blow to Canada’s beef industry. http://www.statcan.ca/cgi-bin/downpub/listpub.cgi?catno=11-621-MWE2004010

147. Topic - Mad Cow Disease However, no cases of mad cow disease impacting cattle or humans have been mad cow disease has an incubation period from two to eight years in cattle. http://healthyamericans.org/topics/index.php?TopicID=24

148. Retesting Reveals Mad Cow Case Scientists believe that mad cow disease is spread through the feeding of There have been no known cases of the human variant of mad cow disease in this http://www.washingtonpost.com/wp-dyn/content/article/2005/06/24/AR2005062401022.

var SA_Message="SACategory=" + 'nation/wires'; Hello Edit Profile Sign Out Sign In Register Now ... Subscribe to SEARCH: News Web var ie = document.getElementById?true:false; ie ? formSize=27 : formSize=24 ; document.write(''); Top 20 E-mailed Articles washingtonpost.com Nation Wires ... E-Mail This Article RSS News Feeds Top News Nation What is RSS? All RSS Feeds ... Dispatch From New Orleans As I drive into New Orleans on the West Bank Expressway, the bruised-looking Superdome is ... More Retesting Reveals Mad Cow Case USDA Criticized for First Clearing Animal of Disease By Marc Kaufman Washington Post Staff Writer Saturday, June 25, 2005; Page A01 New tests have confirmed that a Texas animal that federal officials earlier declared to be free of mad cow disease did have the brain-wasting ailment, the U.S. Agriculture Department announced yesterday. The definitive testing, done in England over the past two weeks, showed that the ailing animal, first flagged as suspicious in November, was infected with mad cow disease. The animal was retested after the USDA's inspector general requested the additional check because of continuing concerns about the sample dismissed by the agency. Agriculture Secretary Mike Johanns, left, said at a news conference that there is no indication the diseased cow had been imported.

149. Bse.org.uk mad cow disease has hit the US What can you do to avoid it? MadToEatMeat.com Free mad cow disease info from the Agriculture Dictionary! http://www.bse.org.uk/

bse.org.uk For Cattle disease try these sponsored links: Mad Cow Disease Facts The latest news and information on mad cow disease www.mad-cow-facts.com Increase "on" time by 6 hours a day with Activa deep brain stimulation. ... alohamedicinals.com/pet.htm Related Links Alopecia areata gullet Fitness Loans ... flowers Search Search the Web This page provided to the domain owner free by Sedo's Domain Parking Buy Domains Sell Domains Premium Domains ... Domain Name

150. CNN.com - Scientists Lower Mad Cow Epidemic Estimate - Feb. 28, 2003 CNN http://cnn.com/2003/HEALTH/conditions/02/28/madcow.disease.ap/index.html

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com Scientists lower mad cow epidemic estimate Story Tools LONDON, England (AP) Scientists have dramatically lowered their estimates of how many people are likely to die from the human form of mad cow disease, though experts say much uncertainty remains. Part of the reason the estimate has dropped is because early predictions of worse-case scenarios did not materialize, forcing a shift in calculations. Experts previously estimated that anywhere between a few hundred to 100,000 people in Britain could eventually get the fatal brain-wasting illness, variant Creutzfeldt-Jakob disease. Now, new research published by the Royal Society, Britain's academy of scientists, forecasts that as few as 10 additional people and as many as 7,000 could get the illness by 2080. Variant CJD has killed 132 people so far 122 of them in Britain. Much uncertainty still surrounds the likely course of the epidemic, said James Ironside, director of Britain's national Creutzfeldt-Jakob disease surveillance unit, who was not involved in the research. Since the disease emerged in England in 1996, the task of predicting how many people are likely to get it and when they will get sick has been a struggle because there have been fewer than 150 cases so far and the incubation period is unknown. Scientists believe it may be longer than 30 years.

151. CNN.com - Mice Experiments May Lead To Mad Cow Treatment - Mar. 5, 2003 CNN http://cnn.com/2003/HEALTH/conditions/03/05/mad.cow.disease.ap/index.html

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com Mice experiments may lead to mad cow treatment Story Tools (AP) Scientists working with mice have blocked the development of a fatal brain illness resembling mad cow disease a boost for efforts toward finding a treatment for the human version. Mice that get weekly injections of an experimental treatment have remained healthy for more than 500 days so far after getting a dose of the rogue proteins that cause the disease. Untreated mice generally died within about 200 days. The treatment sharply reduced the buildup of the dangerous proteins in the spleen, and the researchers hope that further work will show the same effect in the brain. The results are far from providing a useful treatment for the human version of mad cow disease, called Creutzfeldt-Jakob disease, or CJD. For one thing, the experimental treatment failed when begun in mice that had already developed symptoms. Still, the work indicates that the approach is worth pursuing, researchers from Imperial College London and University College London conclude in Thursday's issue of the journal Nature. "We've made a promising start," said Simon Hawke of Imperial College London. But "there is much more developmental work to be done before we can begin to think about translating this research" to treating people.

152. The Atlantic Online Is the US govt. doing enough to prevent madcow disease? http://www.theatlantic.com/issues/98sep/madcow.htm

Home Current Issue Back Issues Premium Archive ... Subscriber Help Browse >> Foreign Affairs Subscribe to our free e-mail newsletters This article is viewable only by Atlantic subscribers. If you are not yet a subscriber, please consider subscribing online now . In addition to receiving a full year (ten issues) of the print magazine at a rate far below the newsstand price, you will be granted instant access to everything The Atlantic Online Click here to join us as an Atlantic subscriber. If you are already a subscriber, and have previously registered for access to the Web site, please log in above. If you are already a subscriber, but have not yet registered for access to the Web site, click here to do so. Home Current Issue Back Issues Forum ... Search

153. BBC NEWS | Europe | 'Mad Cow' Disease Found In Goat European scientists confirm what is thought to be the first known case of mad cow disease in a goat. http://news.bbc.co.uk/2/hi/europe/4216431.stm

News Sport Weather World Service ... Newswatch LANGUAGES Russian Polish Polish Greek ... More Last Updated: Friday, 28 January, 2005, 15:31 GMT E-mail this to a friend Printable version 'Mad cow' disease found in goat Goat meat is subject to the same strict controls as beef A French goat has tested positive for mad cow disease - the first animal in the world other than a cow to have bovine spongiform encephalopathy (BSE). The European Commission says further testing will be done to see if the incidence is an isolated one. The animal, which was slaughtered in 2002, was initially thought to have scrapie, a similar brain-wasting condition sometimes seen in goats. But British scientists have now confirmed the disease was in fact BSE. More than 100 people in the UK have died from vCJD (variant Creutzfeldt-Jakob Disease), the human form of BSE, after eating tainted beef. But the EC stressed on Friday that precautionary measures put in place in recent years to protect the human food chain from contaminated meats meant there was no need for alarm over the latest finding. Markos Kyprianou, EU Commissioner responsible for Health and Consumer Protection, said: "I want to reassure consumers that existing safety measures in the EU offer a very high level of protection.

154. CNN.com - More Mad Cow-linked Herds Under Quarantine - May. 22, 2003 CNN http://cnn.com/2003/HEALTH/05/22/mad.cow.disease/index.html

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com More mad cow-linked herds under quarantine Story Tools VIDEO Canadian authorities announce the discovery of a single case of mad cow disease. CNN's Greg Clarkin reports (May 20) PLAY VIDEO RELATED Mad cow disease reported in Canada Fear, mystery of mad cow disease HEALTH LIBRARY Health Library Men's Health Women's Health Care for the whole family HUMAN THREAT Mad cow disease was first reported in the United Kingdom in 1986, peaking in 1993 with almost 1,000 new cases per week. In 1996, variant Creutzfeldt-Jakob Disease (vCJD) was detected in humans and linked to the mad cow epidemic. Eating contaminated meat and cattle products is presumed to be the cause. Both are fatal brain diseases with unusually long incubation periods, often lasting years. To date, no case of mad cow disease has been identified in the United States. As of April 2, 2002, a total of 125 cases of vCJD had been reported in the world: 117 from the United Kingdom, six from France, and one each from Ireland and Italy. Source: CDC EDMONTON, Canada (CNN)

155. Mad Cow Variant Woman Dying Of Disease CNN http://cnn.com/2001/HEALTH/conditions/04/15/med.us.brain.wastingi.ap/index.html

156. CNN.com - Other Countries Join U.S. In Ban Of Canadian Beef - May. 21, 2003 CNN http://cnn.com/2003/HEALTH/05/21/mad.cow.disease/index.html

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com Other countries join U.S. in ban of Canadian beef Story Tools VIDEO Canadian authorities announce the discovery of a single case of mad cow disease. CNN's Greg Clarkin reports (May 20) PLAY VIDEO RELATED Mad cow disease reported in Canada Fear, mystery of mad cow disease HEALTH LIBRARY Health Library Men's Health Women's Health Care for the whole family THE HUMAN LINK Mad cow disease was first reported in the United Kingdom in 1986, peaking in 1993 with almost 1,000 new cases per week. In 1996, variant Creutzfeldt-Jakob Disease (vCJD) was detected in humans and linked to the mad cow epidemic. Eating contaminated meat and cattle products is presumed to be the cause. Both are fatal brain diseases with unusually long incubation periods, often lasting years. To date, no case of mad cow disease has been identified in the United States. As of April 2, 2002, a total of 125 cases of vCJD had been reported in the world: 117 from the United Kingdom, six from France, and one each from Ireland and Italy. Source: CDC EDMONTON, Alberta (CNN)

157. American Scientist Online - Mad-Cow Disease In Cattle And Human Beings AmericanScientist.org An archive of articles covering original scientific research into astronomy, medical science, anthropology, ecology, technology, http://www.americanscientist.org/template/AssetDetail/assetid/34005

Home Current Issue Archives Bookshelf ... Subscribe In This Section Search Book Reviews by Issue Issue Index Topical Index ... Classics Site Search Advanced Search Visitor Login Username Password Help with login Forgot your password? Change your username see full issue: July-August 2004 Mad-Cow Disease in Cattle and Human Beings Bovine spongiform encephalopathy provides a case study in how to manage risks while still learning the facts Paul Brown Go to Article Other Formats: PDF Of Possible Interest Book Review: Mortal Choices Book Review: Rethinking the Immune System Book Review: Coming: Calamity and Chaos Book Review: A Dark Mirror Book Review: The Shape of Plagues to Come Related Sigma Xi Links Distinguished Lecturer: Kimberly M. Thompson Distinguished Lecturer: Ted Labuza Distinguished Lecturer: Brian Strom Distinguished Lecturer: Joany Jackman ADVERTISEMENTS About American Scientist Site Map Text Archive ... Contact Us

158. Mystery Ailment May Be 'mad Cow' Variant CNN http://cnn.com/2001/WORLD/americas/05/27/mystery.disease.ap/index.html

159. GNN - Genome Affects Human Forms Of “Mad Cow” Disease Last month’s discovery of the first “mad cow” in the United States has rekindled interest in the weird infectious agent that causes the disease and is http://www.genomenewsnetwork.org/articles/2004/01/23/mad_cow.php

Home About Topics Genome Affects Human Forms of “Mad Cow” Disease By Nancy Touchette Posted: January 23, 2004 Email Page Printer Friendly Email GNN GNN News Alerts ... Mad Cow Brain tissue infected with prions has a spongy appearance. Image courtesy NEJM. Mad cow disease is one of several related diseases known as spongiform encephalopathies that can affect several animal species. The disease gets its name from the many holes that perforate brain tissue to give it a spongy appearance in diseased individuals. The infectious agent that is widely thought to cause disease is the prion, a particle of clumped-up protein. This particle, or clump, is made up mostly or entirely from a misshapen protein, known as the prion protein. In its normal form, the prion protein is found in a wide variety of tissues throughout the body, including the brain, immune system, blood, gut, and liver, and causes no disease. But mutations in the protein can cause it to fold abnormally and clump up to form infectious prions. Researchers also believe that new prions can form when a normal prion protein comes into physical contact with an abnormally shaped prion protein. For reasons that are totally mysterious, the bad protein makes the good protein turn bad. How Humans Develop Prion Disease Several different forms of prion disease occur in humans and they may be contracted in several ways. The chance of developing a human prion disease in any form is less than one in a million.

160. Overclockers Club Folding@Home Team Overclockers of the world unite to find cures for diseases such as; cancer, mad cow, and parkinson's. Find information about our team and how to get involved. http://www.overclockersclub.com/folding.php

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