SYMPOSIUM ON ALLERGY Recognizing Drug Allergy How to differentiate true allergy from other adverse drug reactions Michael E. Weiss, MD VOL 117 / NO 5 / MAY 2005 / POSTGRADUATE MEDICINE CME learning objectives - To become familiar with the various types of adverse reactions to medications that can occur
- To understand the diagnostic tests available to help ascertain the cause of an adverse medication reaction
- To learn the importance of a detailed patient history in proper diagnosis of medication reactions
The author discloses no financial interests in this article. Preview : Adverse reactions to medications are an unfortunate but common part of modern medical practice. Although only a fraction of all adverse drug reactions represent an immunologic response, it is important to identify patients who have had an allergic reaction to a particular medication or class of medications. Dr Weiss discusses the various types of adverse drug reactions that can occur and describes the diagnostic measures available for determining whether a patient's reaction is a true drug allergy. A dverse drug reactions are important and frequent complications of medication therapy. An estimated 5% to 15% of patients have adverse reactions to medications. Up to 30% of hospitalized patients experience at least one adverse drug reaction; in addition, about 3% of acute-care medical admissions and 0.3% of hospital admissions are attributed to such reactions(1). Only 5% to 10% of all adverse drug reactions are attributed to allergic (ie, immunologic) reactions. The first step in proper diagnosis of an adverse drug reaction is to understand the different types of reactions that can occur. | |
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