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         Lyells Syndrome:     more detail
  1. Dermatose Bulleuse: Brûlure, Impétigo, Épidermolyse Bulleuse, Épidermolyse Bulleuse Dystrophique, Syndrome de Lyell, Dermite Des Prés (French Edition)

81. World Jewish Congress Online Articles Urgent Medical
Albumin is used as a Volume Expander in hypovolemia and shock syndrome Lyell s syndrome (toxic epidermal necrolysis); nephrotic syndrome; nephritis;
http://www.worldjewishcongress.org/nfo/article.cfm?id=2751

82. Lamotrigine
Rarely, serious skin rashes, including StevensJohnson syndrome and toxic epidermalnecrolysis (Lyell s syndrome) have been reported.
http://www.mentalhealth.com/drug/p30-l06.html
Lamotrigine
Brand name: Lamictal
Drug monograph
September 1999
Contents
Pharmacology
Antiepileptic Lamotrigine is a drug of the phenyltriazine class chemically unrelated to existing antiepileptic drugs (AEDs). Lamotrigine is thought to act at voltage-sensitive sodium channels to stabilize neuronal membranes and inhibit the release of excitatory amino acid neurotransmitters (e.g. glutamate, aspartate) that are thought to play a role in the generation and spread of epileptic seizures. Clinical Trials:
In placebo-controlled clinical studies, lamotrigine has been shown to be effective in reducing seizure frequency and the number of days with seizures when added to existing antiepileptic drug therapy in adult patients with partial seizures, with or without generalized tonic-clonic seizures, that are not satisfactorily controlled. Studies have also been conducted using lamotrigine monotherapy in patients (n=443) newly diagnosed with epilepsy (partial seizures, with or without secondary generalization or primary generalized tonic clonic). Results have shown comparable efficacy (time to first seizure, seizure frequency, percentage of patients seizure-free) with fewer side effects than currently approved therapies. Clinical trials have also demonstrated that patients (any seizure type) can be converted to lamotrigine monotherapy from polytherapy with significant numbers of patients maintaining or improving seizure control. Efficacy was maintained during longterm treatment (up to 152 weeks).

83. The EOPS Source Index 1992
9225 Stefani FH Strampelli s keratoprosthesis in corneal scarring fromLyell s syndrome (toxic epidermal necrolysis); 92-26 Balestrazzi E First
http://www.helsinki.fi/laak/silk/perus/EOPS1992.html
The EOPS Source Index
Go to Home Previous Next 60's ... Notes
Strasbourg, June 1st - 4th, 1992
31st Annual Meeting
Streeten B W
Invasive squamous carcinoma of the cornea: a 20 year incubation period
Witschel H
Bilateral xanthogranuloma of orbit and lid in an adult
Adenoid cystic carcinoma
Sahel J A
Primary orbital melanoma
D'Hermies F D
Orbital involvement by an ethmoidal carcinoma
Mullaney J
Panuveal neurofibromatosis
de Wolff-Rouendaal D
Choroidal melanoma growing in a choroidal naevus in a patient with dysplastic naevus syndrome
McCartney A C E
Familial malignant melanoma of the uvea and p53 (a Victorian melodrama in four acts)
Daicker B
Pleomorphic adenocarcinoma of the ciliary epithelium
Naumann G O H
Melanocytoma of the ciliary body with extrascleral extension
Hanssens M
Medullo-epitheliomatous (?) structures in a congenitally blind eye
Tarkkanen A
Hereditary vitreoretinal degeneration (Wagner's disease)
Libert J
Ultrastructural studies of the vitreous in progressive retinoschisis
Kennedy S
Retinitis pigmentosa in hypobetalipoproteinemia (atypical retinitis pigmentosa with basal linear deposits)
Ohnishi Y
A case of cancer-associated retinopathy
Garner A
Drusen with calcification and secondary neovascularisation
Vogel M H
Retinoblastoma in a 12 year old boy
Uffer S
Retinal tumor in a member of a retinoblastoma family
Neoplastic or nodular reactive proliferation of RPE
Nicolaissen B Jr
The morphology of one week old laser lesions in human retina
Not presented
Mooy C M
Granulomatous reaction to silicon oil
Cunha- Vaz J G
Silicone oil related periretinal membranes

84. The EOPS Author Index - S
additional tooth and cervical cyst; 9225 Strampelli s keratoprosthesis incorneal scarring from Lyell s syndrome (toxic epidermal necrolysis)
http://www.helsinki.fi/laak/silk/perus/EOPSAUTS.html
The EOPS Author Index
Go to Home A B C ... Notes
Alphabetical List of All Members and Guests Alphabet S
Sach, Josef
Guest
Guest
Previous:
Institute of Pathology
3rd Medical Faculty
Charles University
Praha, Czechoslovakia
Eye Clinic
3rd Medical Faculty
Charles University
Praha, Czech Republic
  • 18 years lasting case of conjunctival malignant melanoma
  • Haemangiosarcoma involving ciliary body
    Guest

    Ordinary Member

    Organising Secretary
    Clinique Ophtalmologique Centre Hospitalier Universitaire Strasbourg, France
  • Unusual localized retinal gliosis
  • Unilateral benign medulloepithelioma associated with bilateral retinal detachment
  • Metastatic orbital neuroblastoma
  • Vitreous metastasis from cutaneous melanoma
  • Primary orbital melanoma
  • Orbital nodular fasciitis?
  • Orbital Kaposi sarcoma: an unusual location Not presented
  • Late-onset anterior persistent hyperplastic primary vitreous
  • Histopathology and ultrastructural features of vitreous samples and opercula removed during macular hole surgery Not presented
    Guest
    Faculty of Medicine Barcelona, Spain
  • 85. Galen's Log: A Risk Free Society
    StevensJohnson syndrome, alopecia, exfoliative dermatitis, Lyell s syndrome (toxicepidermal necrolysis), photosensitivity reactions.
    http://galenslog.typepad.com/galens_log/2005/02/a_risk_free_soc.html
    hostName = '.typepad.com';
    Galen's Log
    Inside medicine looking out
    Main
    February 23, 2005
    A Risk Free Society
    One of the TV networks ran a tragic story about 2 young girls who developed Stevens Johnson sydrome after taking ibuprofen over the counter. One died, the other lost her eyesight. These stories serve as grim reminders about the dual nature of any medications, both prescription and non prescription. Adverse reactions abound in almost any type of medication. Let's take a look at ibuprofen in the PDR: CONTRAINDICATIONS MOTRIN should not be used in patients with previously demonstrated hypersensitivity to ibuprofen, or in individuals with a history of allergic manifestations to aspirin or other NSAIDs. Severe anaphylactic-like reactions to ibuprofen have been reported in such patients, some with fatal outcome.
    INCIDENCE LESS THAN 1% Causal Relationship Unknown: The following adverse reactions occurred at an incidence of less than 1% in clinical trials, or were suggested by marketing experience under circumstances where a causal relationship could not be definitely established. They are listed as alerting information for the physician. Allergic: Serum sickness, lupus erythematosus syndrome, Henoch-Sch[omacr ]nlein vasculitis, angioedema. Cardivascular system: Arrhythmias (sinus tachycardia, sinus bradycardia). Hematologic system: Bleeding episodes (e.g., epistaxis, menorrhagia). Metabolic/endocrine: Gynecomastia, hypoglycemic reaction, acidosis. Nervous system: Paresthesias, hallucinations, dream abnormalities, pseudo-tumor cerebri. Special senses: Conjunctivitis, diplopia, optic neuritis, cataracts.

    86. Pediatrics -- Sign In Page
    No cases of Lyell s syndrome or StevensJohnson syndrome were observed.Eighteen children were admitted to a hospital, 17 were seen in emergency departments
    http://pediatrics.aappublications.org/cgi/content/full/peds.2004-0040v1
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    Incidence of Mucocutaneous Reactions in Children Treated With Niflumic Acid, Other...
    Sturkenboom et al. Pediatrics.
    This Article Abstract Full Text (PDF) P ... Alert me if a correction is posted Services E-mail this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Sturkenboom, M. Related Collections
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    87. : The AMEDEO Literature Guide
    Novel treatments for druginduced toxic epidermal necrolysis (Lyell s syndrome).Int Arch Allergy Immunol 2005;136205-16. PubMed Related articles Abstract
    http://www.amedeo.com/medicine/hys/intaaimm.htm
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    Single Articles
    August 2005
  • GAFVELIN G , Thunberg S, Kronqvist M, Gronlund H, et al
    Cytokine and Antibody Responses in Birch-Pollen-Allergic Patients Treated with Genetically Modified Derivatives of the Major Birch Pollen Allergen Bet v 1.
    Int Arch Allergy Immunol 2005;138:59-66.
    PubMed
    Related articles Abstract available
  • KARAKI M , Dobashi H, Kobayashi R, Tokuda M, et al
    Expression of Interleukin-16 in Allergic Rhinitis. Int Arch Allergy Immunol 2005;138:67-72. PubMed Related articles Abstract available
  • OHKI Y , Tokuyama K, Mayuzumi H, Sato A, et al Characteristic Features of Allergic Airway Inflammation in a Murine Model of Infantile Asthma. Int Arch Allergy Immunol 2005;138:51-58. PubMed Related articles Abstract available
  • IIJIMA H , Tulic MK, Duguet A, Shan J, et al NOS 1 Is Required for Allergen-Induced Expression of NOS 2 in Mice. Int Arch Allergy Immunol 2005;138:40-50.
  • 88. Virtual Hospital: P & T News
    Injection site pain, pruritis, rash; Urticaria, ecchymosis, bruising, hematoma,tingling, Lyell s syndrome, StevensJohnson syndrome, exfoliative dermatitis
    http://www.vh.org/adult/provider/pharmacyservices/PTNews/1994/05.94.html
    The Rational Use of Parenteral Ketorolac
    Nancy E. Sloan, Pharm.D.
    Peer Review Status: Internally Peer Reviewed by Charles R. Clark, M.D., Professor, Department of Orthopaedic Surgery Pharmacology
    Ketorolac is a potent inhibitor of the cyclo-oxygenase pathway of arachidonic acid metabolism, resulting in a decrease in prostaglandin and thromboxane products as shown in Figure 1.(2,3) It is structurally and pharmacologically related to tolmetin, zomepirac, and indomethacin.(4) It is structurally and pharmacologically related to tolmetin, zomepirac, and indomethacin.(4) Ketorolac exhibits analgesic, anti-inflammatory, and antipyretic activity. Ketorolac may produce analgesia by inhibiting the synthesis of prostaglandins peripherally and possibly centrally, but does not appear to affect opiate receptors.(4,5) Figure 1: Metabolism of Phospholipid and Arachidonic Acid Pharmacokinetic Properties
    Rapid and complete absorption occurs following intramuscular (IM) ketorolac administration, with a maximum plasma concentration achieved in 45 to 50 minutes. Ketorolac displays characteristics of a two-compartment model. In order to minimize the time delay in achieving adequate analgesic effect and to achieve steady state levels more rapidly, a loading dose equal to twice the maintenance dose is recommended.(5) Studies have shown a significant increase in plasma half-life and a decrease in total plasma clearance in the elderly,(6) and renally impaired(7) subjects compared with young volunteers. No changes occur in clearance with chronic dosing. Metabolism and excretion are outline in Table 1.(3-9)

    89. MedlinePlus Medical Encyclopedia: Topics Beginning With Lo-Lz
    Loeffler s syndrome see Simple pulmonary eosinophilia (Loeffler s syndrome) Lye see Sodium hydroxide; Lyell s syndrome see Erythema multiforme
    http://www.nlm.nih.gov/medlineplus/ency/encyclopedia_Lo-Lz.htm
    @import url(/medlineplus/images/advanced.css); Skip navigation
    Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z
    Medical Encyclopedia Topics beginning with "Lo-Lz"

    90. Press Release Concerning Lamictal (lamotrigine) And Serious Skin Reactions
    such as febrile mucocutaneous syndrome (StevensJohnson syndrome) and toxicepidermal necrolysis (Lyell s syndrome) have been observed.
    http://www.mpa.se/press/press96/lamictal.shtml
    Sweweb Läkemedel Övriga produkter Medicinteknik ... In English
    Box 26, 751 03 Uppsala
    Tel 018-17 46 00,
    Fax 018-54 85 66 registrator@mpa.se
    webmaster@mpa.se

    June 27, 1996
    Press release concerning Lamictal (lamotrigine) and serious skin reactions
    Lamictal (lamotrigine) is a relatively new drug for the treatment of epilepsy. Skin reactions, especially at the beginning of treatment, are well known side effects with Lamictal. Therefore, a slow increase of the dose is important. Despite this, serious mucocutaneous reactions, such as febrile mucocutaneous syndrome (Stevens-Johnson syndrome) and toxic epidermal necrolysis (Lyell's syndrome) have been observed. Warnings of these reactions are included in the product information for Lamictal. So far, 4 cases of serious skin reactions have been seen in Sweden in connection with Lamictal therapy. The Medical Products Agency is at present investigating these cases and the possible causal connection with Lamictal together with the company and the health personnel involved. Patients who are treated with Lamictal and who experience any skin reaction should interrupt the treatment and consult a physician. Otherwise, the patients should not on their own initiative stop treatment with Lamictal.

    91. Science -- Sign In
    Toxic epidermal necrolysis (TEN, Lyell s syndrome) is a severe adverse drugreaction in which keratinocytes die and large sections of epidermis separate
    http://www.sciencemag.org/cgi/content/full/282/5388/490
    You do not have access to this item: Full Text : Viard et al., Inhibition of Toxic Epidermal Necrolysis by Blockade of CD95 with Human Intr..., Science You are on the site via Free Public Access. What content can I view with Free Public Access If you have a personal user name and password, please login below. SCIENCE Online Sign In Options For Viewing This Content User Name Password
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    92. Dr. Koop - Erythema Multiforme
    Lyell s syndrome; StevensJohnson syndrome; Toxic epidermal necrolysis Stevens-Johnson syndrome and toxic epidermal necrolysis are associated with high
    http://www.drkoop.com/ency/93/000851trt.html
    Home Health Reference Erythema multiforme Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library
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    Erythema multiforme
    Injury Disease Nutrition Poison ... Prevention
    Erythema multiforme
    Alternative Names: Lyell's syndrome; Stevens-Johnson syndrome; Toxic epidermal necrolysis
    Treatment: Treatment goals include control of the underlying causes or illnesses, treatment of the symptoms, and prevention of infection. Suspected medications should be discontinued.
    Treatment of mild symptoms may include:
    • Moist compresses applied to skin lesions Medications such as antihistamines to control itching Over-the-counter medications (such as acetaminophen) to reduce fever and discomfort Topical anesthetics (especially for mouth lesions) to ease discomfort that interferes with eating and drinking
    Treatment of severe symptoms may include:
    • Hospitalization and treatment in an intensive care or burn care unit for severe cases, Stevens-Johnson syndrome, and toxic epidermal necrolysis Systemic corticosteroids to control inflammation Intravenous immunoglobulins (IVIG) to stop the process Antibiotics to control secondary skin infections
    Good hygiene and isolation from others may be required to prevent secondary infections Extensive skin involvement may cause the loss of large quantities of body fluids, causing

    93. Dr. Koop - Erythema Multiforme
    Lyell s syndrome; StevensJohnson syndrome; Toxic epidermal necrolysis Raynaud s Disease, Respiratory, Reye syndrome, Rheumatoid Arthritis
    http://www.drkoop.com/ency/93/000851prv.html
    Home Health Reference Erythema multiforme Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library
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    Erythema multiforme
    Injury Disease Nutrition Poison ... Prevention
    Erythema multiforme
    Alternative Names: Lyell's syndrome; Stevens-Johnson syndrome; Toxic epidermal necrolysis
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    94. Upchaar - Health, Medical,India Doctors, Medical Education, All About Jaipur Hea
    Lyell s syndrome. Lyme borreliosis. Lyme disease. Lyme disease primary.Lyme disease - secondary. Lyme disease - tertiary. Lymph follicular hypertrophy
    http://www.upchaar.com/disease l.htm
    "You can change any thing in this country" Emergency Zone : Blood Bank Eye Bank Ambulance 24 Hours Clinic ... Disease Info : L A B C D ... Z Labyrinthitis Lack of intrinsic factor Lacrimal gland tumor Lactase deficiency Lactic acidosis Lactose intolerance Laennec's cirrhosis Lambert-Eaton Syndrome Lamellar ichthyosis Lancefield group B streptococcus Landry-Guillain-Barre syndrome Langerhans cell histiocytosis Language disorder - expressive Larva migrans visceralis Laryngeal cancer Laryngeal nerve damage Laryngitis Late persistent Lyme disease Late syphilis Lateral epicondylitis Lateral rectus palsy Lazy eye Lead poisoning disease LeFort injuries Left-sided heart failure Legg-Calve-Perthes disease Legionella pneumonia Legionnaire's disease Leiomyoma Leiomyoma - intestine Leiomyosarcoma Leishmaniasis Lens opacity Lentigos Leopard syndrome Leprosy Leptospirosis Lesch-Nyhan syndrome Lethal midline granuloma Letterer-Siwe disease Leukemia Leukemic reticuloendotheliosis Leukemoid reaction Leukoplakia Leydig cell tumor LGV Lice - body Lice - head Lice - pubic Lichen planus Lichen simplex chronicus Limb-girdle muscular dystrophies Lipid Disorders - acquired Lipofuscinosis Lipoid nephrosis Listeriosis Little stroke Livedo reticularis Liver abscess Liver cancer Liver cirrhosis Liver disease Liver disease due to alcohol Liver hemangioma Liver metastases Liver spots Lobar intracerebral hemorrhage Lobar sclerosis Lobular capillary hemangioma Lobular GN Localized lymphadenopathy Lockjaw Loeffler's syndrome Lou Gehrig's disease Louis-Bar syndrome Low blood magnesium Low blood phosphate

    95. BARTTERSITE.COM
    Meniere s Disease Rett syndrome Raynaud Asperger s syndrome Treatment Steven Johnson syndrome Lyell s syndrome
    http://www.barttersite.com/gitelman.htm

    96. Dermatopathologie / Activités Scientifiques
    syndrome) withintravenous human immunoglobulins. Burns 27, 652-655, 2001. GE PIERARD.
    http://www.chuliege.be/actsc/26.html
    Dermatopathologie
    G.E. PIERARD, J.E. ARRESE et C. PIERARD-FRANCHIMONT.
    Itraconazole.
    Expert Opinion on Pharmacotherapy, 1, 287-304, 2000.
    C. PIERARD-FRANCHIMONT, C. LETAWE, I. FUMAL, I. VAN CROMPHAUT et G.E. PIERARD.
    Gravitational syndrome.
    Phlebology Digest, 13, 11-12, 2000.
    G.E. PIERARD, J.F. HERMANNS, T. HERMANNS-LE, V. GOFFIN et C. PIERARD-FRANCHIMONT.
    G.E. PIERARD, J.L. NIZET et C. PIERARD-FRANCHIMONT.
    Cellulite: from standing fat herniation to hypodermal stretch marks.
    American Journal of Dermatopathology, 22, 34-37, 2000.
    F. HENRY, N. CLAESSENS, O. MARTALO, A.L. FRAITURE, C. PIERARD-FRANCHIMONT et G.E. PIERARD. G.E. PIERARD. Skin, 3, 11-12, 2000. G.E. PIERARD. EEMCO en de doeltreffendheid van cosmetica. Skin, 3, 11-12, 2000. C. PIERARD-FRANCHIMONT, J.F. HERMANNS, H. DEGREEF et G.E. PIERARD. From axioms to new insights into dandruff. Dermatology, 200, 93-98, 2000.

    97. Stevens-Johnson Syndrome Information Diseases Database
    Erythema multiforme aka/or Lyell s disease aka/or Scalded skin syndrome. may becaused by or feature of + (Follow link for list.
    http://www.diseasesdatabase.com/ddb4450.htm
    Diseases Database Index Sponsors Contact ... Previous Page
    Stevens-Johnson syndrome information
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    5 synonyms or equivalents were found. Stevens-Johnson syndrome
    aka/or
    Toxic epidermal necrolysis
    aka/or
    Erythema multiforme
    aka/or
    Lyell disease
    aka/or
    Scalded skin syndrome Stevens-Johnson syndrome: Definition(s) via UMLS Code translations and terms via UMLS Stevens-Johnson syndrome: specific web sites Send Stevens-Johnson syndrome to medical search engines (JavaScript enabled browsers only.) If your browser has no JavaScript you can still use these:
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    Search using Internet search engines (non-specialist) We subscribe to the HONcode principles of the Health On the Net Foundation Valid XHTML 1.0 Served 2005-09-09 10:36:57 View metadata Last major update 2005-09-03. The medical information here is presented for education, background reading and general interest. The Diseases Database is not a diagnostic or clinical decision-making tool. Please consult your own licensed physician regarding diagnosis and treatment of any medical condition!

    98. Disease, Medication, Symptom Etc Database Index : L Diseases Database
    Lyell s disease see StevensJohnson syndrome Lyme disease see Borrelia burgdorferi Lymecycline Lymph nodes enlarged see Lymphadenopathy
    http://www.diseasesdatabase.com/disease_index_l.asp
    Diseases Database Index Sponsors Contact ... Previous Page
    Disease, medication, symptom etc database index : L
    Search
    La Crosse virus see California encephalitis virus
    Lab abnormality (all) see Laboratory finding
    Labetalol

    Labhardt-Willi-Prader-Fanconi syndrome see Prader-Willi syndrome
    Laboratory finding

    Labour (normal)

    Labour dysfunction see Dystocia
    Labyrinthine fistula

    Labyrinthitis

    Laceration of perineum see Perineal tear Lacidipine Lack of energy see Fatigue Lacrimal canaliculitis Lacrimal gland enlarged Lacrimal sac inflammation see Dacryocystitis Lacrosse encephalitis see California encephalitis virus Lactase deficiency Lactate dehydrogenase Lactate dehydrogenase levels low (plasma or serum) ... Lactate dehydrogenase levels raised (plasma or serum) Lactate levels raised (plasma or serum) see Lactic acidosis Lactation, increased see Galactorrhoea-Hyperprolactinaemia Lacteal cyst see Galactocoele Lactic acidaemia see Lactic acidosis Lactic acidosis Lactitol Lactobacillus acidophilus ... Lactobacillus delbrueckii ss. bulgaricus Lactocele see Galactocoele Lactose intolerance see Lactase deficiency Lactosuria Lactulose Lacunar infarction see Lacunar stroke Lacunar stroke Ladakamycin see 5-Azacytidine LAF 237 see Vildagliptin Lafora body disease Lafutidine Lagophthalmos Lambert type ichthyosis see Ichthyosis hystrix gravior Lambliases see Giardia lamblia Lamellar ichthyosis Lamellar ichthyosis, trichorrhexis invaginata syndrome

    99. EMedicine - Toxic Epidermal Necrolysis : Article By Gregory P Garra, DO
    Synonyms and related keywords TEN, Lyell s disease, mucocutaneous exfoliativedisease, Toxic Shock syndrome. Other Problems to be Considered
    http://www.emedicine.com/EMERG/topic599.htm
    (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Emergency Medicine Infectious Diseases
    Toxic Epidermal Necrolysis
    Last Updated: June 13, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: TEN, Lyell's disease, mucocutaneous exfoliative disease, erythema multiforme, EM, bullous erythema multiforme, Stevens-Johnson syndrome, SJS, mucocutaneous reaction, widespread erythema, necrosis, bullous detachment of the epidermis, SJS-TEN, TEN with spots, TEN without spots AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography
    Author: Gregory P Garra, DO , Clinical Assistant Professor of Emergency Medicine, Stony Brook University School of Medicine; Program Director, Department of Emergency Medicine, Stony Brook University Hospital Coauthor(s): Peter Viccellio, MD , Vice-Chair, Professor, Department of Emergency Medicine, State University of New York at Stony Brook Gregory P Garra, DO, is a member of the following medical societies:

    100. Bextra Erytherma Multiforme
    Toxic epidermal necrolysis (TEN syndrome, or Lyell s syndrome) involves multiplelarge blisters (bullae) that coalesce, followed by sloughing of all or most
    http://www.wrongful-death.com/wrongful_death_lawyer/bextra-multiforme.html
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    Bextra Erythema Multiforme
    BREAKING NEWS: 11-10-04 - BEXTRA MORE THAN DOUBLES RISK OF HEART ATTACK - This week, researchers said a preliminary study indicated that Bextra, a painkiller in the same class as Vioxx, more than doubled the risk of heart attack. Bextra has also been linked to strokes, heart disease, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis and erythema multiforme. Click Here for more information regarding Bextra.
    Erythema multiforme is a skin disorder resulting from an allergic reaction. Erythema multiforme is a type of hypersensitivity (allergic) reaction that occurs in response to medications, infections, or illness. Medications associated with erythema multiforme include sulfonamides, penicillins, barbiturates, and phenytoin. Associated infections include herpes simplex and mycoplasma infections. The exact cause has been attributed to0 the use of Bextra. The disorder is believed to involve damage to the blood vessels of the skin with subsequent damage to skin tissues. Approximately 90% of erythema multiforme cases are associated with herpes simplex or Mycoplasma infections. The disorder occurs primarily in children and young adults.

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