81. Go Ask Alice!: Leukemia Alice, I have a friend who is diagnosed with leukemia. I would like to know what it is and what the survival rate for leukemia is. Good friend. http://www.goaskalice.columbia.edu/0556.html

Mac users: please note that our site is optimized for the Safari browser Colds, aches, pains, and other ailments Leukemia Originally Published: February 17, 1995 Alice, I have a friend who is diagnosed with Leukemia. I would like to know what it is and what the survival rate for Leukemia is. Good friend Dear Good friend, Leukemia is a general term for several types of cancers which are represented by a proliferation of disorganized white blood cells in the bone marrow. They are called leukemic cells, and impair the production of red blood cells, platelets, and normal white blood cells. Leukemic cells circulate throughout the blood, impairing the function of organs such as the liver, spleen, lymph nodes or brain. Leukemias are either acute or chronic, and are classified by the type of abnormal white blood cell present. Acute cases generally develop more rapidly than chronic cases. If acute leukemia goes untreated it can be fatal within a few weeks or months. However with treatment, life can be prolonged and in some instances a complete cure may be provided. Approximately 6-7 new cases of acute leukemia are diagnosed per 100,000 people per year. Chronic cases include lymphocytic leukemia (excess mature looking lymphocytes), and myeloid leukemia (excess white blood cells called granulocytes). There are approximately 4 new cases of chronic lymphocytic leukemia per 100,000 people each year. It usually occurs in people over 50, and is incurable but is not always fatal. Treatment includes transfusions, antibiotics, and in severe cases, use of anticancer drugs, or radiation therapy. The disease progresses slowly, and more than half of those diagnosed with chronic lymphocytic leukemia survive at least five years from time of diagnosis.

82. CNN.com - Researchers Report Promising Results With Leukemia Treatment - May 22, CNN http://www.cnn.com/2000/HEALTH/cancer/05/22/leukeima.drug/index.html

cancer Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Researchers report promising results with leukemia treatment From staff reports May 22, 2000 Web posted at: 1:58 p.m. EDT (1758 GMT) ATLANTA (CNN) A treatment designed to kill cancer cells and not harm healthy tissues, as conventional chemotherapy often does, shows strong promise in tests for patients with chronic myelogenous leukemia, scientists announced at a meeting of the American Society of Clinical Oncology.

83. Elsevier.com - Leukemia Research leukemia Research Clinical and Laboratory Studies Editorsin-Chief leukemia Research is an international journal which brings comprehensive and current http://www.elsevier.com/inca/publications/store/5/8/3/

Home Site map Regional Sites Advanced Product Search ... Leukemia Research Journal information Product description Editorial board Audience Abstracting/indexing For Authors Guide for authors Online Submission Subscription information Bibliographic and ordering information Conditions of sale Dispatch dates Journal related information Impact factor Most downloaded articles Other journals in same subject area About Elsevier ... Select your view LEUKEMIA RESEARCH Clinical and Laboratory Studies Editors-in-Chief: John M. Bennett, Terry J. Hamblin See editorial board for all editors information Description Leukemia Research is an international journal which brings comprehensive and current information to all health care professionals involved in basic and (or) applied clinical research in leukemias, lymphomas, multiple myeloma and other hematologic malignancies. The editors encourage the submission of articles relevant to normal and leukemic hemopoiesis, biochemistry, cell biology, immunology and molecular biology as well as epidemiologic and clinical studies. Specifically, of major interest will be articles that encompass the application of oncogenes, growth factors, cell markers, cell cycle and differentiation agents, novel therapeutics and clinical trials in both the acute and chronic leukemias as well as the myelodysplastic syndromes. In addition we solicit selected articles on the rapidly increasing specialty of marrow or stem cell reconstitution after high dose therapy with curative attempt in patients with a wide range of neoplasms.

84. CNN.com - Living Standards And Childhood Leukemia - August 7, 2000 CNN http://www.cnn.com/2000/HEALTH/mayo/08/07/living.standards/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Living standards and childhood leukemia FROM Living standards and childhood leukemia: Cases of the most common type of childhood leukemia are increasing among British youngsters, and a new study suggests that better living standards may be a cause. Richard J.Q. McNally M.D., of the Royal Manchester Children's Hospital, and colleagues found that the rate of ALL among youngsters living in Oxford in central England is 3-4 times that of children of similar age living in Bombay, India.

85. CNN.com - Health - Possible Link Between Agent Orange, Leukemia - April 19, 2001 CNN http://cnn.com/2001/HEALTH/conditions/04/19/agent.orange/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe set your edition Languages Spanish Portuguese German Italian Danish Japanese Korean Arabic Time, Inc. Time.com People Fortune EW Possible link between Agent Orange, leukemia WASHINGTON (CNN) Research released Thursday suggests a possible association between a child's chance of getting a type of leukemia and a parent's exposure to Agent Orange, a defoliant used during the Vietnam War that already has been linked to several health problems among veterans and their offspring. But a congressionally mandated report from the Institute of Medicine stopped short of establishing a direct cause and effect between Agent Orange and acute myelogenous leukemia (AML), instead calling the evidence "limited or suggestive." Irva Hertz-Picciotto, professor of epidemiology at the University of North Carolina at Chapel Hill and chair of the committee that conducted the study, said researchers saw a 70 percent higher risk of AML for children whose parents served in Vietnam or Cambodia. MESSAGE BOARD The U.S. military

86. EMedicine Health - Leukemia leukemia is a cancer of the blood in which blood cells mature abnormally or incompletely. These abnormal or immature cells accumulate in the body. http://www.emedicinehealth.com/articles/25755-1.asp

Search September 9, 2005 Registration Healthcare Professionals You are in: Cancer and Tumors Leukemia Leukemia Overview Cancer is a process of uncontrolled abnormal cell growth and development. Under normal circumstances, cells are formed, mature, carry out their intended function, and then die. New cells are constantly regenerated in the body to replace those cells and to maintain normal cellular function. Cancer represents the disturbance of this process, which can occur in several ways. Cells may grow and reproduce in a disorganized and out-of-control fashion. Cells may fail to develop properly, so they will not function normally. Cells may fail to die normally. One or a combination of these processes may occur when cells become cancerous. Leukemia is a cancer of blood-forming cells in the bone marrow. These deranged, immature cells accumulate in the blood and within organs of the body. They are not able to carry out the normal functions of blood cells. Normal blood contains 3 major groups of cells: white blood cells, red blood cells, and platelets. All 3 types of blood cells develop from one immature cell type, called blood/marrow stem cells, in a process called hematopoiesis. These stem cells divide and develop to a more developed, but still immature precursor, called a blast, which then develops through several more stages, into a mature blood cell.

87. CNN.com - Health - Newer Drug Holds Off Leukemia Longer - December 14, 2000 CNN http://cnn.com/2000/HEALTH/cancer/12/14/bc.health.leukemia.reut/index.html

cancer Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Newer drug holds off leukemia longer BOSTON, Massachusetts (Reuters) Using the drug fludarabine as the first line of defense keeps chronic lymphocytic leukemia (CLL) at bay longer than standard treatment, but it does not affect overall survival, according to a study in this week's New England Journal of Medicine. CLL is the most common form of leukemia in adults, striking about 8,100 people in the United States each year.

88. Sloan-Kettering - Leukemias For information about our services for children with leukemia, please visit leukemia is a cancer of blood cells that originates in the bone marrow, http://www.mskcc.org/mskcc/html/373.cfm

if(!window.tabs) var tabs = []; var tab = tabs[tabs.length] = []; tab.id = 13; var TAB_WWWROOT = "/mskcc/"; var tabDarkColor = "#336699"; var tabMediumColor = "#99BBCC"; if(window.createHeaderImageCache) createHeaderImageCache(44,512,5626,1072,5664,638,8228); if(window.formatTabs) formatTabs(tabs); Cancer Information Types of Cancer Leukemias Leukemias Leukemia develops when a blood cell undergoes a transformation into a malignant cell one capable of uncontrolled growth. Chronic lymphocytic leukemia and acute myelogenous leukemia and are the most common forms in adults. At Memorial Sloan-Kettering, we offer the best possible clinical care as part of an interdisciplinary team approach. Our leukemia experts continually improve standards of care through clinical research. In this section you can find information about our expertise in treating adults with leukemia, our services, and our research. For information about our services for children with leukemia, please visit Pediatric Leukemias Overview Leukemia is a cancer of blood cells that originates in the bone marrow, the soft, spongy inner portion of certain bones. Acute Lymphocytic Leukemia Acute lymphocytic leukemia (also called acute lymphoblastic leukemia or ALL) is uncommon among adults, but it is the most common type of leukemia in children.

89. CNN - Drug Shows Promise Against One Form Of Leukemia - December 03, 1999 CNN http://www.cnn.com/1999/HEALTH/12/03/leukemia.pill.02/index.html

MAIN PAGE WORLD U.S. LOCAL ... daily almanac MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists. Enter your address: document.write(' '); Or: Get a free e-mail account E-MAIL DISCUSSION: message boards chat feedback CNN WEB SITES: AsiaNow Svenska Norge Danmark ... Italian FASTER ACCESS: europe japan TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: more networks transcripts SITE INFO: help contents search ad info ... jobs WEB SERVICES: health cancer > story page Drug shows promise against one form of leukemia December 3, 1999 Web posted at: 12:13 p.m. EST (1713 GMT) In this story: 'Too good to be true' 'Literally given me my life back' More tests needed RELATED STORIES, SITES ... NEW ORLEANS (CNN) Cancer researchers on Friday reported dramatic results in early clinical trials of an experimental pill designed to combat chronic myelogenous leukemia, one of four common forms of leukemia. The drug has few side effects and may have the potential to destroy other cancers, medical experts said. MORE INFORMATION: Patients and physicians can get more information on the Leukemia drug study by calling the Novartis Oncology Clinical Trials Hotline at 1-800-340-6843 or going to www.novartisoncology.com

90. Sloan-Kettering - Acute Myelogenous Leukemia Acute myelogenous leukemia (AML, also sometimes called acute myeloid leukemia or acute nonlymphocytic leukemia) is the most common leukemia diagnosed in http://www.mskcc.org/mskcc/html/5427.cfm

if(!window.tabs) var tabs = []; var tab = tabs[tabs.length] = []; tab.id = 13; var TAB_WWWROOT = "/mskcc/"; var tabDarkColor = "#336699"; var tabMediumColor = "#99BBCC"; if(window.createHeaderImageCache) createHeaderImageCache(44,512,5626,1072,5664,638,8228); if(window.formatTabs) formatTabs(tabs); Cancer Information Types of Cancer Leukemias Acute Myelogenous Leukemia Acute Myelogenous Leukemia Select an Acute Myelogenous Leukemia Topic - Transplantation - Investigational Approaches Acute myelogenous leukemia (AML, also sometimes called acute myeloid leukemia or acute nonlymphocytic leukemia) is the most common leukemia diagnosed in adults. Treatment approaches for adult leukemia may include chemotherapy, immunotherapy, and stem cell transplantation. Radiation therapy is sometimes used for leukemia in the central nervous system or elsewhere and for pain caused by bone destruction. In this section you can find information about our expertise in treating patients with AML, our services, and our research. Chemotherapy for AML is typically divided into two phases: remission induction and post-remission therapy.

91. Leukemia Drug May Restore Hair Color CNN http://cnn.com/2002/HEALTH/08/07/antigraying.drug.ap/index.html

92. Childhood Acute Lymphoblastic Leukemia - Acute Lymphocytic Leukemia In Children Acute Lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is the most common malignancy in children, representing nearly one third of all pediatric http://www.emedicine.com/ped/topic2587.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Oncology Acute Lymphoblastic Leukemia Last Updated: April 13, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: acute lymphocytic leukemia acute lymphatic leukemia acute lymphoid leukemia , ALL, pediatric cancer, childhood cancer childhood malignancy , inherited genetic syndromes, lymphoblastic leukemia leukemia , leukemic blasts, T cell , T-cell ALL, B cell , B-lineage ALL, BCR-ABL MLL , high-risk ALL, exposure to ionizing radiation , exposure to electromagnetic fields, allogeneic hematopoietic stem cell transplantation HSCT bone marrow failure anemia ... petechiae , bleeding, lymphadenopathy , hepatosplenomegaly, bone pain AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Jeffrey E Rubnitz, MD, PhD , Director of Fellowship Training Program, Associate Professor, Departments of Pediatrics and Hematology-Oncology, University of Tennessee and St Jude Children's Research Hospital Jeffrey E Rubnitz, MD, PhD, is a member of the following medical societies:

93. Myeloproliferative Disease Support Group Information on chronic myelogenous leukemia, polycythemia vera, essential thrombocythemia, agnogenic myeloid metaplasia, myelodysplasia, myelofibrosis. For patients and health professionals. Archives available. http://members.aol.com/mpdsupport/

The MPD-SUPPORT-L Webpage Click here to view the MPD Survey results! Right click the link above and choose "Save Target As". Please be patient while this downloads. This is an Adobe Acrobat file (870k). If you need the free Adobe Acrobat Reader click here Since 1994, our MPD-SUPPORT-L web site and free support email list offers interesting information on chronic myelogenous leukemia, polycythemia vera, essential thrombocythemia, agnogenic myeloid metaplasia, myelodysplasia, and myelofibrosis. Anyone - patient, family member, or health professional, is welcome to join our growing list of subscribers. Our archives are available for you to research information. You can subscribe to our daily digest list by either one of our two easy methods, Our EZ web interface, or by email. Use our EZ web interface to to subscribe, to post a message once subscribed, to reach a listowner, to unsubscribe, to easily vacation stop and restart your mail, to review and change your delivery options, and for an EZ review of our list archives: http://listserv.aol.com/archives/mpd-support-l.html

94. EMedicine - Acute Lymphoblastic Leukemia : Article By Karen Seiter, MD Acute Lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is a malignant (clonal) disease of the bone marrow in which early lymphoid precursors http://www.emedicine.com/med/topic3146.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Hematology Acute Lymphoblastic Leukemia Last Updated: May 10, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: ALL , lymphoid precursor cells, lymphoblasts, malignant lymphoid disorder , cancer, bone marrow malignancy, bone marrow cancer, leukemia , bone marrow failure, lymphoma , bone marrow carcinoma, anemia thrombocytopenia neutropenia , leukemia in children, bone pain, splenomegaly , mediastinal mass, leukostasis, dizziness , palpitations, dyspnea, disseminated intravascular coagulation DIC pneumonia petechiae , ecchymoses, hepatosplenomegaly, lymphadenopathy , Philadelphia chromosome, myeloproliferative disorder AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Karen Seiter, MD

95. Home Page Journal detailing a young girl's battle with leukemia, including bone marrow transplant. Written by her mother. http://www.kellieatkinson.bigpondhosting.com

"I have cancer, it doesn't have me" KELLIE ATKINSON A beautiful, intelligent, brave and courageous 15 year old girl [ Home ] Introduction My Story week 1 My Story week2 My Story week3 ... Letter from a friend Welcome to my web site! If you are visiting this web site you are probably already aware that Kellie was diagnosed with Acute Myeloid Leukaemia (AML) on 28th August 2003. This web site has been designed to give you an overview of what a very beautiful, intelligent, brave and philosophical girl has to go through to return to the life of a normal teenager. A diary record written by her mum, Kathie. Read about her unrelated cord blood stem cell transplant, day to day medical conditions, medications, disappointments and joyous achievements, all milestones on her road to recovery. We update regularly so don't forget to check our latest updates. CHECK OUT THE NEW UPDATES AND PICTURES This web-site was last updated on 29-Aug-2005 12 months since transplant!!! KELLIE HAS ANOTHER BIRTHDAY - HAPPY 17TH KELLIE 2 years since diagnosis Kellie goes to her school formal CHECK OUT MY PHOTO PAGES..

96. Special Days Camps Program in Jackson, Michigan for youth ages 6 to 17 who have or had cancer or leukemia. Partner camp for siblings, winter camp for kids and siblings, short program for ages 5 to 6, FAQs, and news. http://www.specialdays.org

@import "/com/sdstyle.css"; Special Days Camps Special Days Partners Camp: Sunday, July 31 - Saturday, August 6, 2005 Special Days Summer Camp: Saturday, August 6 - Friday, August 12, 2005 ... Tuesday, August 9 - Thursday, August 11, 2005 For children with cancer or leukemia... Special Days Camps provides a safe place to come and enjoy normal childhood camp activities in a healthy, outdoor setting - under the care of skilled medical personnel. Those in treatment are given every chance to participate in all activities. Campers who are off treatment provide a wonderful inspiration to those who are sick. For the brothers and sisters of children with cancer... Special Days Camps provides carefree camping fun "on their own," with friendly and understanding companions. Special Days Winter camp, a reunion for all... A time for all campers to spend some outdoor winter fun with new and old friends. Snow, or no snow, winter camp is a non-stop blitz of fun! Special Days' Mission Statement: Special Days Camps exists to provide a safe and memorable camping opportunity for children, siblings, and their families who have experienced cancer.

97. Help Support The Fight Against Cancer! Richard is running the Vancouver BC Marathon to raise funds for the leukemia and Lymphoma Society. http://www.home.earthlink.net/~dakwon

Help Support The Fight Against Cancer! I'm running the Vancouver BC Marathon in May '03 to raise funds for the NYC Chapter of the Leukemia and Lymphoma Society You're probably here because I notified you somehow about this site. Or, maybe you've stumbled across it just surfing. There's a ton of sports related fundraising sites out there. Regardless, thanks for stopping by, take a look around as long as you're here. Thanks! May 4, 2003 - Marathon Time 3:43 This site is maintained by Richard Park . It is run separately from the Leukemia and Lymphoma Society , and the Vancouver BC Marathon

98. Leukemia & Lymphomas Links to articles about treatment, research and organizations. http://www.cancernews.com/leukemia.htm

Click over the LOGO below to visit the new CancerNews.com site Leukemia, Lymphoma and Multiple Myeloma Click Over the Profiler Link Below to Find Out About State of the Art Treatment Options for Leukemia/Lymphoma Featured Articles Management of Thalidomide Side Effects: The Cleveland Clinic Myeloma Research Program Experience Multiple Myeloma Updates Video Webcasts Leukemia Video News Clips Lymphoma Video News Clips International Myeloma Foundation -A non-profit organization. Site has information on treatment, research and patient support. -Information about Leukemia, Lymphoma, Hodgkin's Disease and Multiple Myeloma. Lymphoma Research Foundation of America -This is a national non-profit organization that provides funds for lymphoma research and patient education. The site has valuable information about these diseases. Cure For Lymphoma Foundation - Funds research and provides education and support to those whose lives have been touched by Hodgkin's disease and non-Hodgkin's lymphoma. The website features information on lymphoma, CFL programs and services, and a section on lymphoma advocacy. -Information about bone marrow, peripheral stem cell, and cord blood transplants. From the basics to the most recent news. This is a great resource!

99. Leukemia / Lymphoma Parent Information Information for parents about the leukemia / Lymphoma treatment program at St. Jude. http://www.stjude.org/leukemia/0,2530,422_2049_10616,00.html

@import url(/StJude/CDA/Common/CSS/default.css); @import url(/StJude/CDA/Common/CSS/default_lists.css); @import url(/StJude/CDA/Common/CSS/default_content_types.css); @import url(/StJude/Common/CSS/St_Jude_Patients_Parents); In order for our site to display correctly you will need a newer version of your web browser. The following browsers support numerous web standards including CSS, XHTML, and the DOM (a universal means of controlling the behavior of web pages): v7 or higher (all platforms), Mozilla FireFox (Windows), Camino (Mac OS X), Galeon (Linux GNOME Desktop) or other browser stemming from the Mozilla.org project. Opera v7 or higher (Windows, Linux) Apple's Safari (Mac OS X) Konqueror (Linux KDE Desktop) Microsoft Internet Explorer v6 or higher (Windows) or v5 or higher (Macintosh) St. Jude Children's Research Hospital Finding Cures. Saving Children. About St. Jude News Donate Now Contact Us ... Ways to Help Leukemia About Leukemia Treatment at St. Jude Optimized Care Team Profiles ... Home Leukemia Leukemia / Lymphoma Parent Information Our experienced team of physicians and researchers have dedicated their lives to finding cures for children just like yours children who suffer from leukemias and lymphomas such as acute lymphoblastic leukemia (ALL)

100. Chronic Myelogenous Leukemia (CML) There are a number of types of leukemia, as you would expect from the number of One of the most common is chronic myelogenous leukemia (also known as http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/CML.html

Chronic Myelogenous Leukemia (CML) Leukemia is an uncontrolled proliferation of one kind of white blood cell (or leukocyte Like all cancers (probably), all the leukemic cells are descended from a single cell that lost the ability to maintain normal control over the cell cycle There are a number of types of leukemia, as you would expect from the number of types of white blood cells (5) and the number of stages they pass through as they mature. One of the most common is c hronic m yelogenous l eukemia (also known as chronic myeloid leukemia) or CML CML arises in a bone marrow stem cell that is the precursor to all the types of blood cells. However, it affects the so-called myeloid lineage (hence the name) that produces granulocytes and macrophages. Link to discussion of the formation of blood cells. As the name suggests, the disease often exists for years with only moderately elevated numbers of leukemic cells (descended from the stem cells) and few symptoms. At some point, however, the patient goes through a "blast crisis" when the leukemic granulocyte-macrophage progenitors The Philadelphia Chromosome (Ph In most cases of CML , the leukemic cells share a chromosome abnormality not found in any nonleukemic white blood cells, nor in any other cells of the patient's body. This abnormality is a reciprocal

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