41. Tobacco Facts And Cancer, Smoking, Larynx Cancer And Quitting Risks of tobacco and smoking. Facts on larynx and lung cancer, emphysema, epidemology and how to quit smoking!! http://www.tobaccofacts.info/

Tobacco use and smoking are very dangerous addictions which commonly cause a wide variety of diseases, cancer and death. The vast majority of tobacco users and smokers are hooked when they are children. During this time period they are easily influenced by peer pressure and advertising. Once hooked, the majority of tobacco users become hopelessly addicted. More than 5 million children living today will die prematurely because of a decision they will make as adolescents-the decision to use tobacco and smoke cigarettes. If you have a dial-up modem, you will have to wait 1 to 2 minutes for the 300Kbytes presentation to fully load. It is worth the wait. In a few seconds, the main presentation screen will be displayed. There is also a HTML version for Dial-Up users: Go To HTML Version Go Back To Home Page Search Site Kevin T. Kavanagh, MD FACS Number of Visits Since 5/4/2004

42. Larynx Cancer 2 Cancer of the Larynx (right false and true vocal cordleft inferior side of This video shows the function of a larynx with a cancer involving the true http://www.tobaccofacts.info/tobacco-videos/larynx_phonation.htm

Larynx Cancer ( Fiberoptic Laryngoscopy) Cancer of the Larynx Video (22 sec) Cancer of the Larynx (right false and true vocal cordleft inferior side of picture) Real Video Windows Media Video 56k Modem 56k Modem LAN LAN ... Best Quality This video shows the function of a larynx with a cancer involving the true vocal cords and arytenoid . The cancer also extends onto the supraglottis . This 68 year old patient had a 30 pack year of smoking and quit smoking 20 years ago Listen To Patient's Voice Download Windows Media 9 Player Download Real One Player at Real.com : Real 1 Player is compatible with Windows 95, 98, XP and Mac webpage last updated

43. New Standard For Voice-Saving Care Of Larynx Cancer Patients NEW STANDARD FOR VOICESAVING CARE OF larynx cancer PATIENTS. Results of a national clinical trial confirm that simultaneous treatment with chemotherapy and http://www.hopkinsmedicine.org/Press_releases/2003/11_26_03.html

Send To A Friend Print This Page Media Contact: Vanessa Wasta wastava@jhmi.edu November 26, 2003 NEW STANDARD FOR VOICE-SAVING CARE OF LARYNX CANCER PATIENTS Results of a national clinical trial confirm that simultaneous treatment with chemotherapy and radiation preserves the voice of patients with advanced larynx cancer without compromising survival rates. The findings, reported in the November 27, 2003, issue of the New England Journal of Medicine are compelling enough to have the combination treatment become the standard of care for such patients, the study's authors report. "Chemotherapy and radiation together are recommended for advanced laryngeal cancer patients who are otherwise in good health and want to preserve their voice," says Arlene Forastiere, M.D., professor of oncology and otolaryngology at the Johns Hopkins Kimmel Cancer Center and chair of the study. "For patients who have other significant medical problems or little support at home, we would recommend radiation alone. In all cases, patients should be followed closely during treatment by a head and neck surgeon, so that surgery can be performed if there is residual or recurrent cancer after treatment." This year, approximately 9,500 Americans will be diagnosed with laryngeal cancer and 3,800 will die from the disease. Experience with combined treatment, Forastiere adds, has reduced the need for complete removal of the larynx from 100 percent to about 15 percent. Removing the larynx leaves patients unable to speak with their natural voice; they typically use speaking aids such as an electronic device. Other previously studied treatment options included radiation

44. CHEMO PLUS RADIATION SAVES VOICE IN LARYNX CANCER the voice in many patients with larynx cancer, Elizabeth Tracey reports. When someone hears a diagnosis of larynx cancer, the biggest concern is often http://www.hopkinsmedicine.org/hnf/hnf_3091.htm

Health Newsfeed CHEMO PLUS RADIATION SAVES VOICE IN LARYNX CANCER ANCHOR LEAD: Using both chemotherapy and radiation together may preserve the voice in many patients with larynx cancer, Elizabeth Tracey reports. When someone hears a diagnosis of larynx cancer, the biggest concern is often the prospect of being mute. Arlene Forastiere, an oncologist at Johns Hopkins, has compared three treatments in these patients, and says removal of the voice box is often not necessary if patients are able to tolerate chemotherapy and radiation together. Forastiere: What we showed was that with the administration of the chemotherapy and radiation together that 88 percent of the patients preserved their larynx in other words only 12 percent or 12 of a hundred people who were enrolled in that study ultimately required laryngectomy. :21 Forastiere says side effects of this double treatment can include an especially sore throat, requiring that patients be followed closely by a team of specialists. Yet even with its probable side effects, for the 13,000 people who are diagnosed with larynx cancer each year in the US this study provides a welcome alternative to losing their voice. At the Johns Hopkins Medical Institutions, I'm Elizabeth Tracey reporting.

45. KION 46 || KEEP IT ON Cancers of the mouth and pharynx (FAREinks) are usually easy to see and diagnose. These include the formation of whitish patches or reddened, http://www.kiontv.com/guides/health/topic.aspx?content_id=5EA76E44-0CFE-4504-BE1

46. The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins In the News Getting Rid of larynx cancer While Saving the Voice Box A landmark study demonstrated that the survival rate for larynx cancer patients http://www.hopkinskimmelcancercenter.org/publications/publication.cfm?DocumentID

47. The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins NEW STANDARD FOR VOICESAVING CARE OF larynx cancer PATIENTS advanced larynx cancer without compromising survival rates. The findings, http://www.hopkinskimmelcancercenter.org/news/index.cfm?action=showthisitem&docu

48. Larynx Cancer Information - National Foundation For Cancer Research give for a cure. Help find a cure for larynx cancer. DONATE here. free enewsletter Sign up to receive e-news about larynx and other types of cancer. http://www2.nfcr.org/site/PageServer?pagename=cancers_larynx

49. Larynx Cancer Information When cancer of the larynx spreads, it is called metastatic laryngeal cancer. The symptoms of cancer of the larynx depend mainly on the size and location http://www.georgetown.edu/departments/radiationmedicine/larynx_cancer.htm

Department of Radiation Medicine 3800 Reservoir Road, NW * Washington, DC 20007-2197 * Tel (202) 784-3320 * Fax (202) 784-3323 Home Our Department General Medical Info Site Index Georgetown Medical Center Georgetown University Introduction The Larynx ... Back to Cancer Home Introduction Each year, more than 12,000 people in the United States learn that they have cancer of the larvnx. This section will give you some important information about the symptoms diagnosis, and treatment of this type of cancer. Researchers continue to look for better ways to diagnose and treat cancer of the larynx, and our knowledge keeps growing. The Larynx This picture shows the larynx and the normal pathways for air and food. The larynx, also called the voice box, is a 2-inch-long, tube-shaped organ in the neck. We use the larynx when we breathe, talk, or swallow. The larynx is at the top of the windpipe (trachea).

50. Treatment Of Throat Cancer, Mayo Clinic In Jacksonville, Fla. The most common cause of cancer of the larynx and pharynx is smoking About 10 percent of patients newly diagnosed with larynx cancer will have another http://www.mayoclinic.org/throatcancer-jax/

Home About Mayo Clinic Jobs Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Throat Cancer Throat Cancer Treatment About the Larynx and Pharynx Symptoms Tumor Staging ... Medical Services Treatment of Throat Cancer Head and neck cancers makes up about 5 percent of cancers in the United States. The American Cancer Society estimates that about 10,000 new cases of laryngeal cancer will be diagnosed in 2002, and 3,900 people will die of the disease. Throat cancers usually develop around age 60, and men are 10 times more likely to develop them than women. Of the new cases this year, 8,100 will be men. The most common cause of cancer of the larynx and pharynx is smoking cigarettes, cigars or a pipe. Drinking large quantities of alcohol also increases the risk. The combination of drinking and smoking is especially conducive to developing throat cancer. Throat cancer is most often a squamous-cell carcinoma, which usually begins on the mucosal surfaces of the larynx, the pharynx or the mouth. About 10 percent of patients newly diagnosed with larynx cancer will have another cancer in the mouth, esophagus or lung. Another 10 to 20 percent will develop a cancer in one of these organs later. That is why it is important for patients with these cancers to continue regular follow-up examinations and to stop smoking and drinking alcohol.

51. M. D. Anderson Cancer Center - Head & Neck Cancer Treatment, Research & Informat Robert Skimin (larynx cancer) When you re in that unknown, it is absolutely vital to find peace of mind. Confidence is what constitutes peace of mind for http://www.mdanderson.org/diseases/head_neck/

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52. Medical Oncology Colorectal Cancer In men, the number of new cases of larynx cancer diagnosed in the last 5 years If larynx cancer is suspected, the doctor will examine for swellings or http://www.sghhealth4u.com.sg/health4u/oncology/types/larynx/larynx1.htm

What is Larynx Cancer The larynx is the voice box. It is made up of the glottis, which is the vocal cords, the area below (subglottis) and the area above (supraglottis) the vocal cords. Any of the cells lining the larynx can become cancerous. How common is Larynx Cancer In men, the number of new cases of larynx cancer diagnosed in the last 5 years has been decreasing compared to the time before. It is six times more common in men than women. Risks and Causes Smoking is one of the commonest risk factors associated with larynx cancer. Alcohol consumption is also a risk factor. Smokers who also drink alcohol have a much higher risk of developing larynx cancer than persons who only smoke or drink alcohol. Symptoms and Signs of Larynx Cancer A person should seek early medical attention if he has a persistently hoarse voice or a persistent sore throat, a painless lump in the neck, pain on swallowing, difficulty swallowing, or noisy breathing known as stridor. As cancer can spread to other organs in the body, in the very late stages there may be symptoms from the lungs or bone. Diagnostic Tests If larynx cancer is suspected, the doctor will examine for swellings or lumps in the neck. An angled mirror that faces downwards is placed against the back of the throat (the palate) to examine the voice box and surrounding organs. Or a flexible tube, two millimetres in diameter, is passed into one of the nostrils to the back of the throat to look for lumps or ulcers in the voice box and surrounding organs. Small pieces of tissue will be removed (biopsy) during this examination to confirm if there is cancer. This examination is performed under anaesthesia. If there is a neck lump, small pieces of tissue may also be removed using a needle and syringe. These procedures, although uncomfortable, usually last about 10 to 15 minutes.

53. BioMed Central | Full Text | Advanced Larynx Cancer To obtain access to Current Treatment Options in Oncology through your institution use the options below. If you would like information about a personal http://www.biomedcentral.com/1527-2729/3/11

home journals A-Z subject areas advanced search ... my BioMed Central To obtain access to Current Treatment Options in Oncology through your institution use the options below. If you would like information about a personal subscription, please contact subs@phl.cursci.com Click here to view an abstract of this article Click here to login if you are already a subscriber to Current Treatment Options in Oncology Subscribe to Current Treatment Options in Oncology Register for a free online trial Ask your librarian to investigate institutional access Athens users please click here to gain access If you believe you are seeing this page in error, or cannot activate your subscription, e-mail us info@biomedcentral.com Terms and Conditions Privacy statement Information for advertisers ... Contact us

54. BioMed Central | Abstract | Advanced Larynx Cancer Opinion Advanced larynx cancer Scott E Strome MD and Eric C Weinman MD Department of Otorhinolaryngology, 200 First Street SW, Mayo Clinic, Rochester, MN, http://www.biomedcentral.com/1527-2729/3/11/abstract

home journals A-Z subject areas advanced search ... Issue 1 Viewing options Abstract Full text PDF Associated material: PubMed record Related literature: Articles citing this article on Google Scholar Other articles by authors Strome SE ... Similar articles (PubMed) Tools: E-mail to a friend Download references Opinion Advanced Larynx Cancer Scott E Strome MD and Eric C Weinman MD Department of Otorhinolaryngology, 200 First Street SW, Mayo Clinic, Rochester, MN, 55906, USA Current Treatment Options in Oncology Published Abstract Despite advances in diagnosis and treatment, the prognosis for patients with stage III-IV laryngeal cancer is not significantly different than it was four decades ago ]. This failure to improve survival is multifactorial and is likely linked to controversy surrounding optimal treatment regimens for a heterogeneous patient and tumor population. At the root of this controversy is a lack of randomized controlled trials that compare different therapeutic options, personal and institutional treatment philosophies, and a paucity of standardized functional and quality-of-life outcome measures for specific treatment modalities. Therapeutic decision making is further complicated by the potential use of organ preservation approaches in some patients ]. Clearly, quality-of-life considerations are an integral part of treatment planning and a well-informed patient is necessary to achieve an optimal result. Philosophically, it is the physician's responsibility to recommend the best treatment option and to explain the other viable treatment strategies. It is our opinion that conservation laryngeal surgery represents the mainstay of treatment for patients with advanced laryngeal carcinomas, whose tumors have characteristics amenable to these approaches and who functionally can tolerate such procedures. For those patients who would likely require a total laryngectomy or who are not suitable for surgical conservation, organ preservation should be used as a primary option in a controlled setting.

55. LARYNX CANCER, LARYNGEAL CANCER , Cancer of the larynx (voice box), and surrounding tissues.......larynx cancer, Laryngeal Cancer. Medical Term. None Specified. http://www.rxmed.com/b.main/b1.illness/b1.1.illnesses/Larynx Cancer Laryngeal Ca

General Illness Information Common Name: Larynx Cancer, Laryngeal Cancer Medical Term: None Specified Description: Cancer of the larynx (voice box), and surrounding tissues. . Usually in patients over age 50 years old. Men are nine times more affected than women. Causes: The cause has not been identified, but there is a very strong association with smoking, and also with heavy alcohol use. Prevention: Do not smoke. Limit alcohol use. See your physician if you develop any early symptoms. Persistent hoarseness . Feeling of lump in the throat. Pain or difficulty while swallowing. Hard, enlarged lumps in the neck. Unexplained weight loss. Tenderness in the neck. Chronic cough. Change in voice quality. Risk Factors Smoking. Alcohol abuse. Chronic vocal-cord inflammation from any cause. Diagnostic tests may include laryngoscopy examination, with vocal cord biopsy . Also CT scan or MRI, bone scan, X-ray of chest to determine if cancer has spread. General Measures: If diagnosed early, radiation therapy or laser cordectomy (excision of vocal cord) may be done, sometimes on an outpatient basis.

56. Excite - Health is being tested in clinical trials for very early cancers of the larynx. Surgery for early larynx cancer can be done by carbon dioxide laser. http://www1.excite.com/home/health/cancer_overview/0,16398,Head Laryn_Treatment,

Health Women Men Seniors ... Cancer More Topics Alternative Healthcast Diseases Kids More info on this condition Treatment Treatment for laryngeal and hypopharyngeal cancer may include surgery, radiation therapy and chemotherapy, either alone or in combination. Surgery or radiation therapy is the most common form of treatment. Chemotherapy is sometimes given when the cancer has spread too far to be treated with surgery and radiation. In a total laryngectomy, the entire larynx is removed. This procedure is usually performed on patients with Stage III and IV cancers. After the voice box is taken out, the windpipe (trachea) is attached to an opening in the neck through which the patient will breathe. These holes, or stomas, require special protection and cleaning. Patients are no longer able to use their vocal cords to speak after a total laryngectomy. Rehabilitation requires developing a new voice by using esophageal speech or a tracheoesophageal fistula. Esophageal speech requires the patient to take air into the esophagus and slowly release the air through the area where the pharynx connects with the esophagus to produce sounds. A tracheoesophageal fistula, which is created by inserting a valve between the trachea and the esophagus, forces air into the esophagus during expiration to produce sounds. Patients may also use an electrolarynx as a sounding source. This device is held in place outside the larynx and produces a sound that is articulated into speech. Other surgical procedures include partial laryngectomy, which preserves some of the voice box and is used to remove smaller cancers; and neck dissection, which removes lymph nodes in the neck that contain cancer.

57. Throat Cancer And The Larynx Discusses larynx cancer and throat cancer statistics and defines the terms GERD, epiglottis, glottis, and esophagus. http://www.throat-cancer-symptoms.com/index.php3

Throat Cancer and the Larynx Larynx cancer is a type of throat cancer that affects the vocal cords and "voice box," also known as the larynx. Understanding larynx cancer requires an awareness of throat and larynx anatomy, larynx cancer risk factors, and throat cancer statistics. Exploring The Larynx, Or "Voice Box" Understanding larynx cancer requires a basic knowledge of throat anatomy. The vocal cords and voice box, or larynx, allow air to travel between the mouth and the lungs. Air passing through the vocal cords causes vibrations, which enable the vocal cords to make sounds. At the top of the larynx, also known as the glottis, is a flap called the epiglottis. The epiglottis prevents food from entering the vocal cords while we eat. Instead, food goes down the esophagus, a tube behind the vocal cords that connects to the stomach. Throat Cancer Statistics Throat cancer statistics reveal that over 9,500 individuals are diagnosed with larynx cancer annually in the United States. Larynx cancer kills 3,800 Americans each year. Throat cancer statistics further reveal that men are four times as susceptible to larynx cancer as women. Evaluations, based on ethnicity, of throat cancer statistics also reveal that African-American men are at fifty percent greater risk of larynx cancer than Caucasian men. Throat cancer statistics also indicate that age increases the risk of larynx cancer. Larynx cancer incidence rates increase after age 55. Risk Factors for Throat and Larynx Cancer: Smoking and GERD

58. Larynx Cancer Risk In Relation To Glutathione S-transferase M1 And T1 Genotypes Increased larynx cancer risk was related to the GSTM1 null genotype odds Glutathione STransferase GSTM3 and GSTP1 Genotypes and larynx cancer Risk http://cebp.aacrjournals.org/cgi/content/abstract/7/1/19

HOME HELP FEEDBACK SUBSCRIPTIONS ... Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager ... Cited by other online articles PubMed PubMed Citation Articles by Jourenkova, N. Articles by Hirvonen, A. ARTICLES Larynx cancer risk in relation to glutathione S-transferase M1 and T1 genotypes and tobacco smoking N Jourenkova, M Reinikainen, C Bouchardy, P Dayer, S Benhamou and A Hirvonen Unit of Cancer Epidemiology (INSERM U351), Institut Gustave-Roussy, Villejuif, France. Glutathione S-transferase (GST) isoenzymes are involved in the detoxification of several tobacco smoke-derived carcinogens. It is thus conceivable that deficiency in GST activity due to homozygous deletion of the GSTM1 and GSTT1 genes (the null genotypes) may modulate susceptibility to smoking-induced cancers. The effects of the GSTM1 and GSTT1 null genotypes on laryngeal cancer risk were evaluated using peripheral blood DNA from 129 larynx cancer patients and 172 noncancer controls, all of whom

59. Glutathione S-Transferase GSTM3 And GSTP1 Genotypes And Larynx Cancer Risk -- Jo The associations between larynx cancer risk and GSTM3 and GSTP1 gene Results from the previous studies on larynx cancer risk associated with the GSTM1 http://cebp.aacrjournals.org/cgi/content/full/8/2/185

HOME HELP FEEDBACK SUBSCRIPTIONS ... Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager ... Cited by other online articles PubMed PubMed Citation Articles by Jourenkova-Mironova, N. Articles by Hirvonen, A. Vol. 8, 185-188, February 1999 American Association for Cancer Research Short Communication Glutathione S -Transferase and Genotypes and Larynx Cancer Risk Nadejda Jourenkova-Mironova Anu Voho Christine Bouchardy Harriet Wikman Pierre Dayer Simone Benhamou and Ari Hirvonen Abstract Top Abstract Introduction Materials and Methods Results Discussion References Glutathione S -transferases (GSTs) are involved in detoxification of reactive metabolites of carcinogens and, therefore, could be potentially important in susceptibility to cancer. The associations between larynx cancer risk and and gene polymorphisms, either separately or in combination with and gene polymorphisms, were evaluated using peripheral blood DNA from 129 cancer patients and 172 controls, all regular smokers. The

60. Stanford Cancer Center - Laryngeal Cancer | Cancer Types | Stanford Cancer Cente Most larynx cancers are squamous cell carcinomas, meaning they arise from flat, Early detection and treatment of larynx cancer greatly improves survival http://cancer.stanfordhospital.com/cancerTypes/headAndNeck/larynx/default?Mode=P

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