21. Kleine-Levin Syndrome Definition - Medical Dictionary Definitions Of Popular Med Online Medical Dictionary and glossary with medical definitions. http://www.medterms.com/script/main/art.asp?articlekey=11542

22. Kleine-Levin Syndrome: A Report Of Three Adolescent Female Patients kleinelevin syndrome (KLS) is an uncommon psychiatric entity in children A variant of the kleine-levin syndrome precipitated by both Epstein-Barr and http://www.ams.ac.ir/AIM/9922/sadeghi9922.html

Kleine-Levin Syndrome: A Report of Three Adolescent Female Patients M. Sadeghi MD Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Abstract Kleine-Levin syndrome (KLS) is an uncommon psychiatric entity in children and adolescents which may present with non-specific and puzzling symptoms. Three cases of KLS in adolescent females are presented and clinical features and probable pathophysiological mechanisms discussed. Keywords Kleine-Levin syndrome Introduction K leine-Levin syndrome (KLS) is a relatively rare sleep disorder characterized by recurrent episodes of hypersomnia, hyperphagia, and mental and behavioral changes. Other features include apathy, irritability, confusion, sexual disinhibition, delusion, hallucination, disorientation memory impairment, incoherent speech and depression or agitation. In about 50% of cases, the syndrome has occurred following a specific factor such as thalamic infarction, Epstein Barr/herpes zoster infection, encephalitis

23. Kleine Levin Syndrome kleinelevin syndrome is a rare disorder characterized by the need for excessiveamounts of sleep (hypersomnolence), (ie, up to 22 hours a day); http://www.bchealthguide.org/kbase/nord/nord1068.htm

var hwPrint=1;var hwDocHWID="nord1068";var hwDocTitle="Kleine Levin Syndrome";var hwRank="1";var hwSectionHWID="nord1068-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Kleine Levin Syndrome Important It is possible that the main title of the report Kleine Levin Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Kleine-Levin Hibernation Syndrome Familial Hibernation Syndrome Periodic Somnolence and Morbid Hunger Disorder Subdivisions None General Discussion Kleine-Levin syndrome is a rare disorder characterized by the need for excessive amounts of sleep (hypersomnolence), (i.e., up to 22 hours a day); excessive food intake (compulsive hyperphagia); and an abnormally uninhibited sexual drive. The disorder primarily affects adolescent males. When awake, affected individuals may exhibit irritability, lack of energy (lethargy), and/or lack of emotions (apathy). They may also appear confused (disoriented) and experience hallucinations. Symptoms of Kleine-Levin syndrome are cyclical. An affected individual may go for weeks or months without experiencing symptoms. When present, symptoms may persist for days to weeks. In some cases, the symptoms associated with Kleine-Levin syndrome eventually disappear with advancing age. However, episodes may recur later during life. The exact cause of Kleine-Levin syndrome is not known. However, researchers believe that in some cases, the disorder may be inherited as an autosomal dominant genetic trait. It is thought that symptoms of Kleine-Levin syndrome may be related to malfunction of the portion of the brain that helps to regulate functions such as sleep, appetite, and body temperature (hypothalamus).

24. BJSM -- Sign In Page kleinelevin syndrome (KLS) most often presents in adolescent males.1 It is The sleeping aviator aeromedical disposition of kleine-levin syndrome. http://bjsm.bmjjournals.com/cgi/content/full/39/2/e7

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH Author Keyword(s) Vol Page [Advanced] Access to this article requires a subscription or payment. Full Text Kleine-Levin syndrome: a unique cause of fatigue in an athlete Commentary Conklin et al. Br J Sports Med. To view this item, select one of the options below: Login via Athens Login for existing subscribers User Name Sign in without cookies. Can't get past this page? Help with Cookies. Need to Activate? Password Forgotten your user name or password? Subscribe Buy the article Pay per Article - You may access this article (from the computer you are currently using) for 2 days for US$12.00 SitePass - You may access all content in British Journal of Sports Medicine Online (from the computer you are currently using) for 30 days for US$30.00. Regain access to an already purchased article if the access period has not yet expired. This Article Abstract Full Text (PDF) Submit a response ... Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Conklin, C M J

25. Kleine-Levin Syndrome: A Unique Cause Of Fatigue In An Athlete * Commentary -- C kleinelevin syndrome (KLS) is a rare disorder characterised, most notably, byperiodic episodes of hypersomnolence and hyperphagia. http://bjsm.bmjjournals.com/cgi/content/abstract/39/2/e7

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS Author Keyword(s) Vol Page [Advanced] This Article Full Text Full Text (PDF) Submit a response ... Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Conklin, C M J Articles by McCrory, P Related Collections Depression Other Neurology Drugs: psychiatry Adolescent medicine ... Related Article Br J Sports Med CASE REPORT Kleine-Levin syndrome: a unique cause of fatigue in an athlete C M J Conklin and J E Taunton University of British Columbia, Vancouver, BC, Canada Correspondence to: Mr Conklin ABSTRACT Kleine-Levin syndrome (KLS) is a rare disorder characterised, most notably, by periodic episodes of hypersomnolence and hyperphagia. Associated features of the disorder include a lack of concentration

26. Kleine-Levin Syndrome Foundation Hall Of Fame HOME PAGE BACK. ©Copyright 20002005 kleine-levin syndrome Foundation, Inc.Developed and Maintained by Commerce Developers. http://www.klsfoundation.org/HallofFame.htm

Hall of Fame The Kleine-Levin Syndrome Foundation, Inc. is very grateful to its supporters for their generosity. With their contributions we have been able to provide information and support to those suffering from KLS. The KLS Foundation plans to continue exchanging information with the public and the medical community to determine the cause of KLS and find a cure to this life-altering disorder. We extend a most sincere thank you to all of our contributors. Founders Founders have contributed $25,000 and above Guardians Guardians have contributed Steve Farber Fund Benefactors Benefactors have contributed Helga Erber Nettie Farber Katherine Maier Patrons Patrons have contributed Leaders Leaders have contributed Libby and Nancy Fischer Freishtat Family Fund of Combined Jewish Philanthropies Frederic and Susan Jacobs Herman and Judith Swartz Fund of Combined Jewish Philanthropies Sustainers Sustainers have contributed Rachel Albert Trust Brent and Rachel Dibner Barry and April Farber The Gronner Family Revocable Trust Ralph and Taren Metson Andrew S. Offit and Suzanne Altman Offit

27. Kleine-Levin Syndrome Diary Of Jeff Sagel This is the first case of kleinelevin syndrome that Children s Hospital has everseen. ©Copyright 2000-2005 kleine-levin syndrome Foundation, Inc. http://www.klsfoundation.org/Jeff.htm

Kleine-Levin Syndrome Diaries The following is the diary of Jeff Sagel. FIRST EPISODE Sat., Jan.22, 1994 NOTE* Jeff grew 6" over the summer preceding his first episode and 1 1/2" from the time he was admitted until he went back to the hospital at the beginning of March. ** Jeff had chicken pox when he was 4 years old. Then he had shingles when he was 10 years old. ** Do either of these things have anything to do with this illness? Perhaps hormones or a chemical imbalance? Perhaps chicken pox virus manifesting itself in different form? ** This episode lasted 7 days. SECOND EPISODE Fri., Nov. 4, 1994 THIRD EPISODE Sun., Aug. 11, 1996 FOURTH EPISODE-Nov. 1996 Nov., 1996 Jeff saw Dr. Sherman at Children’s. We discussed the best way to take care of the remaining cavities. We decide that since the xylocaine seemed to bring on an episode, we shouldn’t take that route for the rest because it would take so many trips and so many chances to go into sleep mode. So, we decide to do laughing gas and fill all the teeth at once and pull his wisdom teeth while he is out. It’s set for Mon., Dec.16, 1996. Sun. Dec. 15, 1996 Jeff came home from work early (1:00 P.M.) and went straight to bed. I couldn’t wake him at 6:00 for dinner. I tried again at 10:30 because he’s not allowed to eat after midnight. but could not wake him. FIFTH EPISODE Tues., April 8, 1997

28. The Sleeping Princess kleinelevin syndrome is a rare disorder that causes cataplexy like sleep,excessive appetite and abnormal sex drive. It strikes mainly during the teen http://sleepdisorders.about.com/cs/sleepandchildren/a/princess.htm

var zLb=14; var zIoa1 = new Array('Related Resources','What Is Hypersomnia?','http://sleepdisorders.about.com/cs/whatisnarcolepsy/a/hypersomnia.htm','Sleep and Children','http://sleepdisorders.about.com/cs/sleepandchildren/index.htm','All About Narcolepsy','http://sleepdisorders.about.com/cs/narcolepsy/'); var zIoa2 = new Array('Elsewhere on the Web','KLS World Organization','http://www.klsworld.com/','NINDS Kleine-Levin Syndrome Information Page','http://www.ninds.nih.gov/health_and_medical/disorders/kleine_levin.htm','Kleine Levin Syndrome','http://www.psychnet-uk.com/dsm_iv/kleine_levin_syndrome.htm'); zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a71' About Sleep Disorders Sleep and Children The Sleeping Princess Sleep Disorders Essentials Sleep Disorders - The Basics Try a Quiz ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Sleep Disorders newsletter! See Online Courses Search Sleep Disorders Stay up to date!

29. Kleine-Levin Syndrome - General Practice Notebook kleinelevin syndrome is characterised by episodes of somnolence and increasedappetite, often lasting for days or weeks and with long intervals between http://www.gpnotebook.co.uk/cache/-456130552.htm

Kleine-Levin syndrome Kleine-Levin syndrome is characterised by episodes of somnolence and increased appetite, often lasting for days or weeks and with long intervals between them. In this syndrome patients can always be roused from the day-time sleep. However they are often irritable on waking and occasionally aggressive. Some patients are muddled and experience depression, disorientation and hallucinations. The combination of sleep disturbance and appetite disorder have pointed to a possible hypothalamic disorder. However there is no convincing evidence for this aetiology. Click here for more information...

30. Arquivos De Neuro-Psiquiatria - ABSTRACT kleine-levin syndrome is characterized by periodic hypersomnia, We describe a typical case of kleine-levin syndrome associated with apparent http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000300021

31. Arquivos De Neuro-Psiquiatria - ABSTRACT A case of kleine-levin syndrome, with chronic severe periodic hypersomniais Multiple Sleep Latency Test findings in kleine-levin syndrome. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1998000400021

32. Kleine-Levin Syndrome A Unique Cause Of Fatigue In An Athlete A classical case of a rare disorder characterized by hypersomnolence and hyperphagia.The subject is a male adolescent athlete. http://www.psychiatrysource.com/psychsource/Case_Studies/Child/Adolescent/articl

33. Kleine-Levin Syndrome kleinelevin syndrome - Provides information and support for those people whohave KLS or kleine-levin syndrome is a rare disorder characterized by the http://www.health-nexus.com/kleine-levin_syndrome.htm

The #1 Health information site Health-Nexus.Net Health-Nexus.Org Home ... Up Search Health-Nexus for: Match ALL words Match ANY word Email this page to a friend ! Post a question or comment on our Message Board Home Page Health Specialties Health News ... Alternative Health Options Substance Abuse Animal Health Search: Books Magazines Video Keywords: Find it Here Kleine-Levin Syndrome Kleine-Levin Syndrome Kleine-Levin Syndrome -KLS- is a rare sleep disorder that causes random episodes of excessive sleeping for indefinite periods of time, and when... Kleine-Levin Syndrome Information Page: National Institute of ... Kleine-Levin Syndrome eCureMe.com Neurology Allergy Physician Directory Dentist Directory Hospital Directory Kleine-Levin Syndrome more about Kleine-Levin Syndrome... Kleine-Levin Syndrome Provides information and support for those people who have KLS or who have a loved one with KLS and to provide them the opportunity to get in touch with other KLS persons. NORD - National Organization for Rare Disorders, Inc.

34. Arch Neurol -- Abstract: A Pathologic Basis For Kleine-Levin Syndrome, January 1 The findings suggest a viral cause for kleinelevin syndrome. Kleine-Levinsyndrome An autoimmune hypothesis based on clinical and genetic analyses http://archneur.ama-assn.org/cgi/content/abstract/39/1/25

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 39 No. 1, January 1982 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Carpenter S Ochs R Articles that cite this article Contact me when this article is cited A pathologic basis for Kleine-Levin syndrome S. Carpenter, R. Yassa and R. Ochs A patient with Kleine-Levin syndrome, typical except that onset was at 39 years of age, died during a symptomatic period. Autopsy disclosed recent and old lesions in the medial thalamus involving intralaminar, medial, and some dorsal nuclei as well as the pulvinar. Despite massive microglial infiltration, there was minimal neuronal loss. The hypothalamus was not involved. The findings suggest a viral cause for Kleine-Levin syndrome.

35. Arch Neurol -- Abstract: Familial Kleine-Levin Syndrome: Two Siblings With Unusu kleinelevin syndrome is a rare, sporadic disorder, with discrete spells of CSF hypocretin-1 levels in narcolepsy, kleine-levin syndrome, http://archneur.ama-assn.org/cgi/content/abstract/59/12/1959

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 59 No. 12, December 2002 Featured Link E-mail Alerts Observation Article Options Full text PDF Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Katz JD Ropper AH Articles that cite this article ISI Web of Science (2) ... Contact me when this article is cited Topic Collections Neurology, Other Topic Collection Alerts Familial Kleine-Levin Syndrome Two Siblings With Unusually Long Hypersomnic Spells Joshua D. Katz, MD Allan H. Ropper, MD Arch Neurol. Kleine-Levin syndrome is a rare, sporadic disorder, with discrete spells of hypersomnolence occurring during adolescence, variously accompanied by megaphagia, behavioral changes, psychosis, and mild autonomic symptoms. Familial cases have not previously

36. Kleine-Levin Syndrome - Talk Medical Humanfriendly medical definition of kleine-levin syndrome. http://www.talkmedical.com/medical-dictionary/8024/Kleine-Levin-Syndrome

Home Medications Medical Dictionary Talk Medical ... Medical Dictionary Newsletter Subscribe to the free monthly health digest. Relevant health articles just for you. Tell a friend Kleine-Levin Syndrome Kleine-Levin syndrome: A rare condition characterized by excessive need for sleep, food, and sexual disinhibition. Most people with Kleine-Levin syndrome are adolescent males. When awake, they may be confused, irritable, and lethargic, and some have hallucinations. The cause is unknown, although current theory holds that Kleine- Levin syndrome is caused by an inherited autosomal dominant trait that affects the hypothalamus gland. Most cases resolve over time without treatment. Print this page About Talk Medical Help Contact Us ... Terms and Conditions

37. Clinical Case Studies -- Sign In Page kleinelevin syndrome is a rare disorder characterized by alternating periods of The kleine-levin syndrome Case report and review of the literature. http://ccs.sagepub.com/cgi/content/refs/2/1/70

JOURNAL HOME HELP CONTACT US SUBSCRIPTIONS ... SEARCH QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This item requires a subscription to Clinical Case Studies Online. The Diagnosis and Cognitive-Behavioral Management of Kleine-Levin Syndrome: A Case... Kulas et al. Clinical Case Studies. This Article Abstract Full Text (PDF) References ... Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Reprints and Permissions To view this item, select one of the options below: Sign In User Name Sign in without cookies. Can't get past this page? Help with Cookies. Need to Activate? Password Forgot your user name or password? Purchase Short-Term Access Pay per Article - You may access this article (from the computer you are currently using) for 1 day for US$35.00 Pay for Admission - You may access all content in Clinical Case Studies Online (from the computer you are currently using) for 24 hours for US$75.00. Regain Access - You can regain access to a recent Pay per Article or Pay for Admission purchase if your access period has not yet expired.

38. The Diagnosis And Cognitive-Behavioral Management Of Kleine-Levin Syndrome: A Ca kleinelevin syndrome is a rare disorder characterized by alternating periods ofexceedingly prolonged sleep and disordered waking and normal sleep and http://ccs.sagepub.com/cgi/content/abstract/2/1/70

JOURNAL HOME HELP CONTACT US SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: Clinical Case Studies, Vol. 2, No. 1, 70-78 (2003) DOI: 10.1177/1534650102239089 This Article Full Text (PDF) References Alert me when this article is cited ... Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Reprints and Permissions The Diagnosis and Cognitive-Behavioral Management of Kleine-Levin Syndrome A Case Study Joseph F. Kulas Jean E. Dumas Douglas M. Dollison Purdue University Kleine-Levin syndrome is a rare disorder characterized by alternating periods of exceedingly prolonged sleep and disordered waking and normal sleep and alert waking. Wakeful periods during an episode are usually marked by social withdrawal and accompanied by a variety of maladaptive behaviors, including hallucinations, delusions, sexual disinhibition, severe anxiety, depression, memory impairment, and increased appetite. Due to the rarity and complexity of the disorder, Kleine-Levin can be easily misdiagnosed.

39. Penn State Faculty Research Expertise Database (FRED) , A rare condition characterized by recurrenthypersomnias Kleine Levin Critchley Syndrome, Kleine Levin Syndrome......kleinelevin syndrome. http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D017593

40. Kleine-Levin Syndrome And Encephalitis.,Sethi S, Bhargava Subhash C: Indian Jour Indian Journal of Pediatrics is an open access http://www.ijppediatricsindia.org/article.asp?issn=0019-5456;year=2002;volume=69

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