1. KLS World Organization kleinelevin syndrome is a complex medical disorder that causes random episodesof excessive There are no tests to diagnose kleine-levin syndrome (KLS). http://www.klsworld.com/

2. Kleine-Levin Syndrome Information Page: National Institute Of Neurological Disor Offers an information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). http://www.ninds.nih.gov/disorders/kleine_levin/kleine_levin.htm

Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system More about Kleine-Levin Syndrome Studies with patients Research literature Press releases Search NINDS... (help) Contact Us My Privacy NINDS is part of the National Institutes of Health You are here: Home Disorders Kleine-Levin Syndrome NINDS Kleine-Levin Syndrome Information Page Get Web page suited for printing Email this to a friend or colleague Table of Contents (click to jump to sections) What is Kleine-Levin Syndrome? Is there any treatment? What is the prognosis? What research is being done? ... Related NINDS Publications and Information What is Kleine-Levin Syndrome? Kleine-Levin syndrome is a rare disorder that causes recurring periods of excessive drowsiness and sleep (up to 20 hours per day). Symptoms, which may last for days to weeks, include excessive food intake, irritability, disorientation, lack of energy, and hypersensitivity to noise. Some patients may also experience hallucinations and an abnormally uninhibited sex drive. Affected persons are normal between episodes, although depression and amnesia may be noted temporarily after an attack. It may be weeks or more before symptoms reappear. Onset is typically around adolescence to the late teens. The disorder is 4 times more common in males than in females. Symptoms may be related to malfunction of the hypothalamus, the part of the brain that governs appetite and sleep.

3. Kleine-Levin Syndrome Foundation, Inc. Provides information and support for those people who have KLS or who have a loved one with KLS and to provide them the opportunity to get in touch with other KLS persons. http://www.kleinelevin.com/

Welcome to the Kleine-Levin Syndrome Foundation, Inc. Website Mission Statement KLS is a rare medical disorder that first manifests in adolescence, characterized primarily by episodes of excessive sleep and altered behavior. The KLS Foundation provides information and support to those diagnosed with KLS and their families. The Foundation exchanges information with patients and the medical community to help in the diagnosis and care of those affected by KLS. Our goals are to raise awareness, support scientific research, to find effective treatment and ultimately find a cure for Kleine-Levin Syndrome. History The website was first developed in 1998 by Cindy and Dick Maier and their son, Stephen, who has KLS. It began as a way for the family to find just one other person with KLS and evolved into a way to support families and individuals with KLS when they discovered hundreds of other people affected by KLS. In 1999, they formed the Kleine-Levin Syndrome Foundation, Inc., a non-profit organization, to help others with KLS and eventually determine the cause and cure for KLS. What is KLS?

4. Kleine-Levin Syndrome kleinelevin syndrome -KLS- is a rare sleep disorder that causes random episodes of excessive sleeping for indefinite periods of time, and when http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Untitled Document I suffer from a rare disorder called kleinelevin syndrome, (KLS). Kleine-LevinSyndrome is a sleep that robs a teenager s life. http://www.klsworld.com/goals.shtml

6. Kleine-Levin Syndrome ECureMe.com Resource Links Physician Directory Dentist Directory Hospital Directory kleinelevin syndrome more about kleine-levin syndrome http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. Kleine-Levin Syndrome (www.whonamedit.com) kleinelevin syndrome A strange condition of unknown aetiology which almost exclusively affects young males aged 15-25 years. Also known as http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Kleine-Levin Syndrome Information Page National Institute Of kleinelevin syndrome information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. Kleine-Levin Syndrome (www.whonamedit.com) kleinelevin syndrome A strange condition of unknown aetiology which almostexclusively affects young males aged 15-25 years. Also known as Critchley s http://www.whonamedit.com/synd.cfm/1398.html

Home List categories Eponyms A-Z Biographies by country ... Contact Whonamedit.com does not give medical advice. This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor. A recommendation: Hypography is an open community about science and all things related Kleine-Levin syndrome Also known as: Critchley's syndrome Kleine-Levin-Critchley syndrome Synonyms: Hypersomnia periodica, hibernation syndrome, hypersomnia-bulmia syndrome, hypersomnia-megaphagia syndrome, periodic hypersomnia-megaphagia syndrome, periodic somnolence, periodic somnolence and morbid hunger syndrome. Associated persons: MacDonald Critchley Willi Kleine Max Levin Description: A strange condition of unknown aetiology which almost exclusively affects young males aged 15-25 years. Characterized by periods lasting from days to weeks of attacks of somnolence accompanied by excessive food intake, and various mental symptoms. Common mental symptoms are confusion, irritability, restlessness, euphoria, hallucinations, delusions, and schizophreniform states. Attacks may occur every 3 to 6 months and last from 2 to 3 days. Between attacks the patients recover completely and the sleep periods usually disappear in adult age. This syndrome may easily be confused for other neurological, metabolical or psychiatric disease

10. Kleine-Levin Syndrome Press Releases National Institute Of kleinelevin syndrome information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. Www.whonamedit.com kleinelevin syndrome. A strange condition of unknown aetiology which almostexclusively affects Kleine-Levin-Critchley syndrome (kleine-levin syndrome) http://www.whonamedit.com/syndlist.cfm/41

Home List categories Eponyms A-Z Biographies by country ... Contact Whonamedit.com does not give medical advice. This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor. A recommendation: Hypography is an open community about science and all things related Eponyms in category: Psychology and psychiatry 131 main and alternative entries found. Abels' test The traditional number-sorting test for evaluating the capacity for concentration, and for diagnosing disturbances of concentration. Ahasuerus' reaction A variant of Münchhausen’s syndrome. Ahasuerus' syndrome (Münchhausen's syndrome) A type of malingering or factitious disorder in which the patient, usually a vagrant, wander from hospital to hospital, feigning severe illness of dramatic and emergency nature in order to be admitted. Alice in Wonderland syndrome A psychopathological syndrome of distorted space, time and body image.

12. BBC - H2g2 - Kleine Levin Syndrome (UG) Created 2nd May 2005 Kleine Levin Syndrome (UG) Front Page What is h2g2? Who's Online Write an Entry Announcements Feedback h2g2 Help http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Kleine-Levin Syndrome -- ECureMe.com UPDATED SARS INFORMATION,Check health symptoms, make a self diagnosis, ask adoctor or veterinarian online, view an encyclopedia of diseases treatments, http://www.ecureme.com/emyhealth/data/Kleine-Levin_Syndrome.asp

DisplayAd("468","60"); eCureMe Life : Your Healthy Living. Click Here! Welcome, eCureMe.com Select a Health Topic ADD/ADHD Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Erectile Dysfunction Eye Care Fertility Fitness Gastrointestinal Health Glands and Hormones Gynecologic Health Hair Loss Headache Healthcare Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Parkinson's Disease Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Disease Women's Health Workplace Health September 9, 2005 eCureMe Life Medical Supplies Calorie Count Physician Search ... Hospital Directory Kleine-Levin Syndrome more about Kleine-Levin Syndrome This is a rare syndrome that occurs mostly in younger males, characterized by bouts of uncontrollable sleep that last up to two days. Such bouts of sleep are followed by hypersexuality, increased hunger, confusion, and irritability upon awakening. These attacks usually occur three or four times per year. A history of neurological injury may contribute to the syndrome. Symptoms commonly disappear by 40 years of age. DisplayAd("120","90");

14. News - TopAbstracts In Sleep Disorders 07/07/2005 Webcasts/CME archive Recent cases Sleep Disorders. kleine-levin syndrome Cases archive http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Kleine-Levin Syndrome - Center For Narcolepsy - Stanford University School Of Me kleinelevin syndrome (“KLS”) is a rare sleep disorder characterized by The kleine-levin syndrome Foundation (www.klsfoundation.org) funds in part this http://med.stanford.edu/school/Psychiatry/narcolepsy/KLS.html

School of Medicine Home Departments Center for Narcolepsy Center for Narcolepsy Home Contact Info Research Update History ... Kleine-Levin Syndrome Kleine-Levin Syndrome (KLS) The Stanford University Center for Narcolepsy has launched a study on Kleine-Levin Syndrome. Why this study? answer Is Kleine-Levin Syndrome an auto-immune disease? answer What is the Stanford project for HLA study in KLS? answer Who can enroll? answer What do I engage myself to do if I take part? answer What is the procedure for enrollment? answer What does it cost? answer Is there any risk in taking part in the study? answer When is the study beginning/ending? answer When and how will I receive my results? answer Can I change my mind? answer Contact information jump Why this study? The cause of KLS is unknown. All diagnostic test results on KLS patients to date, including brain imagery, EEG, serum virus titres, and CSF examination, have been normal. However, nearly half of the patients experience a non-specific, mainly flu-like infectious disease few days before the onset of their first KLS episode. The rarity of the KLS, compared to the high frequency of flu-like diseases in the general population, suggests that some patients may be more predisposed to KLS. This vulnerability may be genetic. Is Kleine-Levin Syndrome an auto-immune disease In KLS, the association of an infection before the onset of a disease, a young age at onset, a recurrence of symptoms and possible genetic predisposition is suggestive of an autoimmune disease. Various autoimmune diseases are tightly linked to a specific human leukocyte antigen (HLA) typing (this is a group that is not, like group A, B, O, on our red cells, but on our white cells). The immune system indeed distinguishes self-antigens from foreign antigens through the cell surface expression of the highly polymorphic HLA glycoprotein antigens. HLA system (allele HLA-DQB1*0602) is highly associated with another sleep disorder, narcolepsy. It has been poorly studied in KLS patients, but a recent study in Europe yield a higher than controls frequency of the HLA-DQB1*201 allele in 30 KLS patients, a group that has been associated to various auto-immune diseases. It is now necessary to extend and specify the measure to a much larger number of patients and families.

16. The Sleeping Princess kleinelevin syndrome is a rare disorder that causes cataplexy like sleep, excessive appetite and abnormal sex drive. It strikes mainly during the http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. CSF Hypocretin-1 Levels In Narcolepsy, Kleine-Levin Syndrome, And CSF hypocretin1 levels in narcolepsy, kleine-levin syndrome, and other hypersomnias and neurological conditions Y Dauvilliers1 2 3 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. Kleine-Levin Syndrome kleinelevin syndrome Updated January 11, 2005 Kleine Levin Syndrome WhoNamed It? kleine-levin syndrome Southern Cross Health Insurance http://www.noah-health.org/en/sleep/specific/kleinelevin.html

Skip navigation About NOAH Help English Spanish Both Advanced NOAH Sleep Disorders Change text size: Kleine-Levin Syndrome Updated: January 11, 2005 Kleine Levin Syndrome Yale New Haven Health Kleine Levin Syndrome WebMD Kleine Levin Syndrome Who Named It? Kleine-Levin Syndrome Southern Cross Health Insurance Kleine-Levin Syndrome Information Page National Institute of Neurological Disorders and Stroke Researched by NOAH Contributing Editor: Pattie Mongelia, MLIS, The New York Public Library NOAH Sleep Disorders > Kleine-Levin Syndrome Health Topics Index A to Z Page of the Month Advanced Search ... Feedback

19. Kleine-Levin Syndrome Kleine-Levin Hibernation Syndrome Familial kleinelevin syndrome Kleine-Levin Hibernation Syndrome Familial Hibernation Syndrome Periodic Somnolence and Morbid Hunger Kleine-Levin http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

20. Specific Disorders & Problems kleinelevin syndrome Information Page National Institute of Neurological Disordersand Stroke More information grey line. Narcolepsy http://www.noah-health.org/en/sleep/specific/

Skip navigation About NOAH Help English Spanish Both Advanced NOAH Sleep Disorders Change text size: Updated: May 12, 2005 Apnea, Sleep Sleep Apnea - What is It? National Heart, Lung and Blood Institute Bed Wetting (Enuresis) What Parents Need to Know About Bedwetting KidsHealth Bruxism (Teeth Grinding) Bruxism (Teeth Grinding) Simple Steps to Better Dental Health Circadian Rhythm Disorders Frequently Asked Questions Circadian Sleep Disorders Association Exploding Head Syndrome Exploding Head Syndrome Mayo Clinic Hypersomnia (Excessive Daytime Sleepiness) Hypersomnia Information Page National Institute of Neurological Disorders and Stroke Insomnia ABC's of ZZZ's National Sleep Foundation Jet Lag Beating Jet Lag: Make the Most of Your Travels GORP Kleine-Levin Syndrome Kleine-Levin Syndrome Information Page National Institute of Neurological Disorders and Stroke Narcolepsy Narcolepsy Information Page National Institute of Neurological Disorders and Stroke Night Sweats Sleep Hyperhidrosis (Night Sweats, Excessive Sweating) Sleep Well Nightmares and Night Terrors Nightmares and Terrors Covenant Healthcare, Knoxville, TN

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