41. Kernicterus - Patient UK kernicterus Patient UK. A directory of UK health, disease, illness and related medical websites that provide patient information. http://www.patient.co.uk/showdoc/40000455/

PatientPlus articles are written for doctors and so the language can be technical. However, some people find that they add depth to the articles found in the other sections of this website which are written for non-medical people. Kernicterus Bilirubin encephalopathy It is a complication of neonatal jaundice . The word kernicterus means yellow kern, kern being the structures of the brain that are most commonly affected. They are the basal ganglia, hippocampus, geniculate bodies and cranial nerve nuclei, especially the oculomotor, vestibular, and cochlear. The cerebellum can also be affected. At postmortem examination a characteristic yellow stain is seen in those structures. Acute bilirubin encephalopathy is the clinical manifestation of bilirubin toxicity. There is hypotonia followed by hypertonia, opisthotonus (backward arching of the neck), or retrocollis (backward arching of the back) or both. It is taken as synonymous with kernicterus. Much of the traditional teaching about neonatal jaundice and kernicterus has been revised. It is the premature baby who is at risk and kernicterus rarely affects a term infant unless bilirubin levels are exceptionally high. A high level of physiological jaundice, especially in breast fed babies, seems benign and resolves spontaneously without complications. Epidemiology: Kernicterus occurs in all part of the world but is more frequent where G6PD deficiency is common. Numbers fell in the 1970s and 1980s only to rise again in the 1990s.

42. ► Rh Incompatibility kernicterus; Rhinduced hemolytic disease of the newborn; Hydrops fetalis Hydrops fetalis and kernicterus have decreased markedly in frequency as a http://www.umm.edu/ency/article/001600.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Disease Nutrition Surgery Symptoms Injury ... Z Maryland Medical Center Programs UM Hospital for Children Home Medical Reference Encyclopedia (English) Toggle English Spanish Rh incompatibility Overview Symptoms Treatment Prevention Definition: Rh incompatibility is a condition which develops when there is a difference in Rh blood type between that of the pregnant mother (Rh negative) and that of the fetus (Rh positive). Alternative Names: Kernicterus; Rh-induced hemolytic disease of the newborn; Hydrops fetalis Causes, incidence, and risk factors: During pregnancy , red blood cells from the fetus can get into the mother's bloodstream as she nourishes her child through the placenta. If the mother is Rh negative, her system cannot tolerate the presence of Rh positive red blood cells. In such cases, the mother's immune system treats the Rh positive fetal cells as if they were a foreign substance and makes antibodies against the fetal blood cells. These anti-Rh antibodies may cross the placenta into the fetus, where they destroy the fetus' circulating red blood cells. First-born infants are often not affected (unless the mother has had previous miscarriages/abortions, which could have sensitized her system) as it takes time for the mother to develop antibodies against the fetal blood. However, second children who are also Rh-positive may be harmed.

43. Pediatric Pathology The yellow staining in the brain of a neonate is known as kernicterus. Increased unconjugated bilirubin, which accounts for the kernicterus, http://www-medlib.med.utah.edu/WebPath/PEDHTML/PED242.html

The yellow staining in the brain of a neonate is known as kernicterus. There is a coronal section of medulla on the left and cerebral hemisphere on the right demonstrating kernicterus in deep grey matter of hemisphere and brain stem. Increased unconjugated bilirubin, which accounts for the kernicterus, is toxic to the brain tissue. Kernicterus is more likely to occur with prematurity, low birth weight, and increased bilirubin levels.

44. Definition Of Kernicterus - WordReference.com Dictionary kernicterus Definition from dictionary. 1, kernicterus. an abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow http://www.wordreference.com/definition/kernicterus

Word Reference .com kernicterus A noun kernicterus an abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow staining and tissue damage Category Tree: cognition knowledge noesis information ... icterus kernicterus Need more information? Ask a question in the forum. Look up "kernicterus" at Merriam-Webster Look up "kernicterus" at dictionary.com English Definition Home Suggestions Search Tips See Also: Kerbala Kerbela kerbstone kerchief ... Kerouac kernicterus: in French in Italian in Spanish

45. Kernicterus kernicterus is a rare neurological disorder characterized by excessive levels of bilirubin in the blood (hyperbilirubinemia) during infancy. http://www.bchealthguide.org/kbase/nord/nord233.htm

var hwPrint=1;var hwDocHWID="nord233";var hwDocTitle="Kernicterus";var hwRank="1";var hwSectionHWID="nord233-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Kernicterus Important It is possible that the main title of the report Kernicterus is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Bilirubin Encephalopathy Disorder Subdivisions None General Discussion Kernicterus is a rare neurological disorder characterized by excessive levels of bilirubin in the blood (hyperbilirubinemia) during infancy. Bilirubin is an orange-yellow bile pigment that is a byproduct of the natural breakdown of hemoglobin in red blood cells (hemolysis). Toxic levels of bilirubin may accumulate in the brain, potentially resulting in a variety of symptoms and physical findings. These symptoms may include lack of energy (lethargy), poor feeding habits, fever, and vomiting. Affected infants may also experience the absence of certain reflexes (e.g., Moro reflex, etc.); mild to severe muscle spasms including those in which the head and heels are bent backward and the body bows forward (opisthotonus); and/or uncontrolled involuntary muscle movements (spasticity). In some cases, infants with kernicterus may develop life-threatening complications. Resources March of Dimes Birth Defects Foundation 1275 Mamaroneck Avenue White Plains, NY 10605

46. Kernicterus News - Healthcare Industry Today kernicterus. Service for healthcare industry professionals and analysts. Constantly updated news and information about kernicterus. http://www.healthcareindustrytoday.com/news/Kernicterus

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47. Kernicterus - Information & News Early postpartum visits with pediatricians may help prevent a dangerous complication associated with jaundice, according to the presentation, ? http://www.news-medical.net/?keyword=Kernicterus

48. Kernicterus Lawsuit Overview - Find Trial Lawyers And Attorneys With Experience kernicterus Overview - Find Trial Lawyers and Attorneys with Experience in kernicterus Personal Injury Law. Contact an attorney who can help you protect http://www.injuryboard.com/view.cfm/Topic=311

t = location.href.split('?'); qs = (t[1] != null)?t[1]:'t=0'; document.writeln(""); Advertise On InjuryBoard.com September 9, 2005 An estimated 300,000 workplace injuries occur each year in the United States. Personal Injury Guidant Defibrillator Recall Vioxx / Rofecoxib Celebrex / Celecoxib ... Children's Health Matters Kernicterus Overview If you or a family member has been injured, contact a personal injury attorney today. Just fill out InjuryBoard.com's on-line questionnaire and have a personal injury lawyer review your potential personal injury claim - free of charge. Ask an Attorney Kernicterus is a debilitating and potentially deadly condition that may appear in newborns. The condition typically occurs in infants suffering from jaundice . Jaundice affects the liver's ability to process bilirubin, a byproduct of red blood cell disposal. Excess bilirubin can accumulate in the brain causing Kernicterus. The condition is characterized by drowsiness , vomiting, feeding problems, neck and back spasms, rolling of the eyes, mental retardation cerebral palsy hearing problems vision problems and death.

49. Hill Health Topics A-Z - Kernicterus kernicterus. National Organization for Rare Disorders. Important It is possible that the main title of the report kernicterus is not the name you expected. http://www.healthwise.net/hillhealth/Content/StdDocument.aspx?DOCHWID=nord233&SE

50. Kernicterus what is kernicterus, definition of kernicterus,kernicterus. http://www.english-dictionary.us/meaning/kernicterus.asp

English Dictionary Advanced Kernelly Kernelling Kernelled ... Kerf kernicterus an abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow staining and tissue damage See also: jaundice Kernigs sign Kerning kernite ... English dictionary Add the dictionary search box to your site! Translation agency Word of the day: Quintilllion

51. HON - News : Health Tip: Does Your Newborn Have Kernicterus? kernicterus, left untreated, can lead to brain damage, cerebral palsy and hearing loss, the CDC says. It also can cause vision problems and mental http://www.hon.ch/News/HSN/521324.html

Speech On / Off HONcode sites All Web sites HONselect News ... X Y Z Browse archive: A J J M ... J Other news for: Parenting Child Development Liver Resources from HONselect Health Tip: Does Your Newborn Have Kernicterus? Symptoms include yellowing of the skin and eyes (HealthDayNews) Lots of babies are born with jaundice, indicated by a yellowing of the skin and the whites of the eyes. The condition is normally caused by overproduction of a substance produced by the liver called bilirubin. In most cases, the jaundice quickly goes away by itself. But if the infant's color grows too yellow or doesn't go away, it could indicate a serious condition called kernicterus, the U.S. Centers for Disease Control and Prevention says. Kernicterus, left untreated, can lead to brain damage, cerebral palsy and hearing loss, the CDC says. It also can cause vision problems and mental retardation. If you're concerned about your newborn's jaundice, contact your pediatrician. ScoutNews LLC Resources from HONselect HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject. Infant, Newborn

52. Kernicterus Is Damage To The Brain Centers Of Infants Caused By Jaundice kernicterus is damage to the brain centers of infants caused by jaundice. Newborn babies are often polycythemic , meaning they have too many red blood http://www.krctraining.com/CRA Definitions/kernicterus.htm

Kernicterus is damage to the brain centers of infants caused by jaundice. Newborn babies are often "polycythemic", meaning they have too many red blood cells. When they break down the cells, one of the by-products is bilirubin, which circulates in the blood, and causes jaundice. In adults and older children, jaundice is harmless in and of itself. But the tissues protecting the brain (the blood-brain barrier) are immature in newborns. The bilirubin penetrates the brain, and literally stains the nerve bodies, causing irreversible damage. Depending on the level of exposure, the effects range from unnoticeable to severe brain damage.

53. Unbound Bilirubin In A Term Newborn With Kernicterus -- Ahlfors And Herbsman 111 Unbound Bilirubin in a Term Newborn With kernicterus. Charles E. Ahlfors, MD and Oded Herbsman, MD. Department of Pediatrics http://pediatrics.aappublications.org/cgi/content/extract/111/5/1110

QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Full Text Full Text (PDF) P ... Citation Map Services E-mail this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed ... Cited by other online articles Search for citing articles in: ISI Web of Science (2) PubMed PubMed Citation Articles by Ahlfors, C. E. Articles by Herbsman, O. Related Collections Related AAP Red Book topics: Malaria PEDIATRICS Vol. 111 No. 5 May 2003, pp. 1110-1112 EXPERIENCE AND REASON Unbound Bilirubin in a Term Newborn With Kernicterus Charles E. Ahlfors, MD and Oded Herbsman, MD Department of Pediatrics California Pacific Medical Center San Francisco, California 94118 Abbreviations: The first 300 words of the full text of this article appear below. INTRODUCTION In premature newborns, bilirubin-induced changes in the auditory brainstem response (ABR) begin at unbound (nonalbumin-bound and kernicterus becomes likely at levels between In term newborns, however, unbound bilirubin

54. Hyperbilirubinemia And Kernicterus: 50 Years Later -- Ip Et Al. 114 (1): 263 -- The authors further reported that kernicterus did not occur in 200 Indirect evidence from the decreasing prevalence of kernicterus since the http://pediatrics.aappublications.org/cgi/content/full/114/1/263

QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Extract Full Text (PDF) P ... Citation Map Services E-mail this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed ... Cited by other online articles Search for citing articles in: ISI Web of Science (2) PubMed PubMed Citation Articles by Ip, S. Related Collections Office Practice PEDIATRICS Vol. 114 No. 1 July 2004, pp. 263-264 COMMENTARY Hyperbilirubinemia and Kernicterus: 50 Years Later Abbreviations: TSB, total serum bilirubin In 1952, Hsia et al reported that 50% of infants with erythroblastosis developed kernicterus. The authors further reported that kernicterus fetalis when the hospital policy was to keep the serum bilirubin been proved that bilirubin is the actual cause of brain damage, tests of serum bilirubin in infants with erythroblastosis fetalis serve as extremely valuable guides to treatment." There is no doubt that bilirubin plays a major role in the development of central nervous system pathology. High-quality studies

55. Kernicterus - Definition From Biology-Online.org Definition and other additional information on kernicterus from BiologyOnline.org dictionary. http://www.biology-online.org/dictionary/kernicterus

Forum Tutorials Dictionary Directory ... K kernicterus kernicterus (Science: paediatrics) Disorder due to jaundice in a newborn baby with high blood levels of the pigment bilirubin that is deposited in the brain resulting in damage . The level of bilirubin is monitored in newborns to determine whether treatment is needed to prevent kernicterus. With brain affected , it is also called bilirubin encephalopathy Search the dictionary About Us Contact Us Link to Us Chemistry ... Equations

56. 2003 Federal/State Partnership Meeting - Hot Topics - Kernicterus President, Parents of Infants Children with kernicterus (PICK) Textonly Transcript. spacer, spacer, spacer. spacer, spacer, spacer http://www.cademedia.com/archives/mchb/partnership2003/hottopic_kernicterus.htm

Kernicterus Michele Puryear, M.D., Ph.D. Chief, Genetics Services Branch, DSCHSN Text-only Transcript Sue Sheridan, M.I.M., M.B.A. Text-only Transcript PowerPoint Presentation Sue Sheridan, M.I.M., M.B.A. Martin J. Haltie, Esq. President, Partnership for Patient Safety (p4ps) Text-only Transcript PowerPoint Presentation Martin J. Haltie, Esq. President, Partnership for Patient Safety (p4ps) Sue Sheridan, M.I.M., M.B.A. Text-only Transcript Links for video ( ) and audio ( ) may require the PowerPoint Viewer (for users who don't already have PowerPoint): PowerPoint Viewer Related text materials ( Acrobat Reader: Please visit our Tech Help Conference recording and internet development provided by The Center for the Advancement of Distance Education Please report technical problems to the webmaster . This site uses WebTrendsLive to collect site statistics.

57. Log In Problems Care related to the management of neonatal hyperbilirubinemia should be based on three fundamental principles (1) evidencebased practice, http://www.medscape.com/viewarticle/497029

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58. Log In Problems This report underscores that to prevent kernicterus, newborns must be screened and promptly treated for hyperbilirubinemia. http://www.medscape.com/viewarticle/414615

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59. Pediatrics Hyperbilirubinemia And Kernicterus 50 Years Later Full text of the article, Hyperbilirubinemia and kernicterus 50 years later from Pediatrics, a publication in the field of Health Fitness, http://www.findarticles.com/p/articles/mi_m0950/is_1_114/ai_n6110978

60. Nursing: Unwelcome Return For Kernicterus Full text of the article, Unwelcome return for kernicterus from Nursing, a publication in the field of Health Fitness, is provided free of charge by http://www.findarticles.com/p/articles/mi_qa3689/is_200311/ai_n9324440

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles Nursing Nov 2003 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Unwelcome return for kernicterus Nursing Nov 2003 Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. NEONATAL JAUNDICE Because of shorter hospital stays for newborns, severe jaundice, which can cause hearing loss and brain damage or kernicterus, is going unnoticed in some infants. Caused by excess bilirubin in the blood, jaundice may not develop until several days after birth. About 60% of American newborns have jaundice, although many recover without treatment. But an accumulation of excess bilirubin is toxic to the brain.

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