41. Keratoconus keratoconus. Up. This is a condition that is characterized clinically by a thinningof the cornea which leads to ectasia centrally with a conelike http://insight.med.utah.edu/opatharch/cornea/keratoconus.htm

Home Up Contributors Submission Information ... Site Map This is a condition that is characterized clinically by a thinning of the cornea which leads to ectasia centrally with a cone-like out-pouching of the cornea. Histologically, the epithelium and the stroma of the cornea centrally are often thinned(#21967). There can also be multiple focal disruptions of epithelial basement membrane and Bowman's layer anteriorly (#21968). In addition, Descemet's membrane may rupture in this condition resulting in acute corneal edema or hydrops. High Power #21968 Low Power #21967 Home Up Conjunctiva Glaucoma ... Site Map John A. Moran Eye Center 50 North Medical Drive Salt Lake City UT 84132 Telephone 801.581.2581 Fax 801.581.3357

42. Keratoconus Intacs Intacs is a minimally invasive, FDAapproved surgical procedure for keratoconus in patients whose vision is not adequately corrected with contact lenses or glasses. Learn more about the procedure and how it works. http://www.harvardeye.com/keratoconus.html

Rigid gas permeable contact lenses are one option for keratoconus. As the name implies, these lenses have a rigid shape, allowing them to create a new, smooth front surface for the eye. They can provide acceptable vision, but unfortunately they can become very uncomfortable and can easily fall out. They are also considerably more costly than soft contact lenses. In the past, when rigid contact lenses failed, the only other option for treating keratoconus was corneal transplantation. This procedure requires a recovery period of six to 18 months before stable vision can be achieved. After recovery, many patients still require rigid contact lenses to see well. Intacs is the newest treatment for keratoconus among patients who can not tolerate contact lenses. Intacs are tiny (0.25 mm thickness) acrylic rings that are placed between the layers of the cornea. These rings were first designed to treat nearsightedness, and they are currently FDA approved only for this use. However, they have been the subject of considerable research in keratoconus, and several studies have shown they can help provide a more normal shape to a patient whose cornea is weakened by keratoconus. The FDA is currently reviewing the approval of Intacs for keratoconus, and approval is expected by the end of 2004.

43. Intacs For Keratoconus keratoconus is a noninflammatory progressive eye disease that affects the cornea keratoconus is generally thought to remain fairly stable after age 40. http://insight.med.utah.edu/patient_care/mvc/tech_research/intacs.htm

Home Up Contact Us Site Map (KEHR-a-toh-kohn-nus) Since the cornea is responsible for focusing light, abnormalities of the cornea can affect the way we see. Patients experience near-sightedness, where distance vision is out of focus. Patients also struggle with irregular astigmatism where vision is blurred or distorted. The condition usually involves both eyes and often starts in the late teens and progresses though adulthood. The disease progresses slowly, but can stop at any stage from mild to severe. Keratoconus is generally thought to remain fairly stable after age 40. While most clinicians believe that Keratoconus has a primary genetic factor, researchers believe that most patients have some combination of genetic and environmental factors that contribute to their disease. Factors that are thought to be associated with Keratoconus are chronic eye rubbing and poorly fitting contact lenses. Scientists have found that a high percentage of Keratoconus patients show cell death within the stroma. The stroma is the middle tissue layer of the cornea that is responsible for its strength. Cell death may lead to stromal weakening and thinning. Different theories about why this occurs are being investigated. The primary management for the disease begins with fitting the patient with glasses. As the disease progresses, rigid gas permeable contact lenses may be required. The rigid lenses mask the corneal irregularities and provide better visual correction.

44. Treating Keratoconus With Intacs FDA approved treatment of keratoconus with Intacs. Learn about the disorder, the Intacs procedure, and find a doctor. http://www.intacsforkeratoconus.com

FREE FLASH Player Required - www.macromedia.com Enter Keratoconus Site: FLASH SITE HTML SITE Website best viewed at 800x600 or higher Flash Player required to view FLASH site - Download the FLASH Player From www.macromedia.com

45. DJO | Digital Journal Of Ophthalmology keratoconus (KC) is a noninflammatory condition of the cornea in which there is keratoconus comes FROM the Greek word meaning conical cornea. http://www.djo.harvard.edu/site.php?url=/patients/pi/425

46. Keratoconus keratoconus is a thinning of the cornea, typically causing distortion and loss of See the story of this first ever keratoconus surgery in the state, see http://www.wangvisioninstitute.com/keratoconus.htm

Dr. Ming Wang Staff Doctors In the News Why WVI? ... ICL/Bioptic Keratoconus Artificial Cornea Fuchs Pterygium MedSpa ... Financing Keratoconus is a thinning of the cornea, typically causing distortion and loss of vision. In severe cases, the only treatment is a corneal transplant. However, Dr. Wang now performs two procedures which may delay or eliminate the need for corneal transplant in patients with this debilitating eye disease. The state's first femtosecond laser - Intacs procedure performed to stop the disease progression in keratoconus and restore vision. On January 20, 2005 Dr. Wang performed the world's first Femtosecond laser assisted INTACS in a patient whose keratoconus had recurred on the corneal graft tissue. Rather than consider another corneal transplant, Dr. Wang placed a segment in the graft to rearrange the shape of the eye, improve the vision, and make contact lens wear possible. News Channel 4, Nashville, January 20, 2005. " Innovative Eye Surgery Performed Locally "

47. Keratoconus - Wikipedia, The Free Encyclopedia keratoconus, or cone eye, is an eye condition or disease in which the corneathins and keratoconus and the associated vision loss, if in both eyes, http://en.wikipedia.org/wiki/Keratoconus

You did it! Over US$240,000 was donated in the 21 day fund drive. Thank you for your generosity! You are still welcome to make a donation or purchase Wikimedia merchandise Keratoconus From Wikipedia, the free encyclopedia. Keratoconus Keratoconus , or "conical cornea" (from kerato- cornea and conus cone), is an eye condition or disease in which the cornea thins and changes shape to be more like a cone than a parabola. Contents Symptoms and diagnosis Prevalence and cause Contact lenses Corneal transplant ... edit Symptoms and diagnosis Keratoconus can cause the vision to become distorted quite badly, with "ghosting", "streaking", and light sensitivity all often reported. The exact nature of the visual distortion introduced by kerataconus is most clearly seen with a point of light on a dark background – instead of seeing one moon the person may see over 100 images spread out in a fairly complex and random pattern. The pattern does not change from day to day, but over the seasons it often takes on new forms. Doctors tend not to ask exactly what the patient sees, but rather test the vision on a standard Snellen chart of progressively smaller letters. Definitive diagnosis is obtained using

48. EMedicine - Keratoconus : Article Excerpt By: Barry A Weissman, OD, PhD keratoconus keratoconus (KC) is a progressive, noninflammatory, bilateral (butusually asymmetrical) disease of the cornea, characterized by paraxial http://www.emedicine.com/oph/byname/keratoconus.htm

(advertisement) Excerpt from Keratoconus Synonyms, Key Words, and Related Terms: KC, corneal disease, stromal thinning, corneal scarring, irregular astigmatism, myopia, vision loss, Fleischer ring, Descemet membrane, intracorneal plastic rings, Intacs, corneal transplantation, penetrating keratoplasty, PKP, contact lens, contact lenses, CL, CL wear, contact lens wear, eye allergies, ocular allergies, eye rubbing Please click here to view the full topic text: Keratoconus Background: Keratoconus (KC) is a progressive, noninflammatory, bilateral (but usually asymmetrical) disease of the cornea, characterized by paraxial stromal thinning that leads to corneal surface distortion. Visual loss occurs primarily from irregular astigmatism and myopia and secondarily from corneal scarring. Pathophysiology: All layers of the cornea are believed to be affected by KC, although the most notable features are the thinning of the corneal stroma, the ruptures in the Bowman layer, and the deposition of iron in the basal epithelial cells, forming the Fleischer ring. Breaks in and folds close to the Descemet membrane result in acute hydrops and striae, respectively. Frequency: In the US: Reported prevalence in the general population varies (50-200 per 100,000), perhaps with differences in diagnostic criteria. It is commonly an isolated ocular condition but sometimes coexists with other ocular and systemic diseases.

49. About Keratoconus keratoconus is an irregular protrusion of the cornea, the clear surface over thecolored The only clue to a keratoconus diagnosis may be from corneal http://webeye.ophth.uiowa.edu/dept/service/contactlens/Conditions/keratoconus.ht

50. Contact Lens Options For Keratoconus I have keratoconus. Are there any new contact lens options available to me?keratoconus is an irregular protrusion of the cornea, the clear tissue over the http://webeye.ophth.uiowa.edu/dept/service/contactlens/FAQ/keratoconus2.htm

51. Keratoconus keratoconus is a usually inherited condition that causes the clear front coveringof the eye (cornea) to degenerate and thin, leading to a coneshaped bulge http://vision.about.com/od/glossary/g/keratoconus.htm

var zLb=4; var zIoa2 = new Array('Suggested Reading','Common Eye Diseases','http://vision.about.com/od/othereyediseases/'); zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a43' About Vision Vision Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Vision newsletter! See Online Courses Search Vision Stay up to date! Compare Prices Email to a friend ... Print this page Suggested Reading Common Eye Diseases Most Popular Baby Eye Color Children's Eye Color Chirac Eye Problems Vision Symptoms ... Lucentis for AMD What's Hot Eye Twitches The Right Eye Doctor Ray Charles and Blindness Men's Eyeglass Frames ... PureVision Contact Lens adunitCM(150,100,'x55') Glossary From Marilyn Haddrill Your Guide to Vision FREE Newsletter. Sign Up Now! Definition: Keratoconus is a usually inherited condition that causes the clear front covering of the eye ( cornea ) to degenerate and thin, leading to a cone-shaped bulge and distorted vision. zau(256,420,100,'ri','http://z.about.com/5/o/c.htm?gs='+gs,'')

52. Keratoconus keratoconus is a deterioration of the structure of the cornea with gradual bulgingfrom the normal round shape to a cone shape. This condition causes . http://www.healthcentral.com/ency/408/001013.html

Dr. Dean TV Specials Newsletters Home ... Health Tools Search Choose a Health Topic * All Health Topics * Acne Addictions AIDS/HIV Alcohol Abuse Allergies Alternative Medicine Alzheimer's Arthritis Asthma Attention Deficit Disorder (ADHD) Backache Bipolar Affective Disorder Birth Control Blood Blood Pressure Bone/Joint/Tendon Bowel Brain Breast cancer Cancer Cerebral Palsy Cholesterol Cramps Crohn's Disease Cysts Dental/Oral Depression Diabetes Diet, Fitness, Looks Disabled/Special Needs Drug Abuse Ear/Nose/Throat Eating/Appetite Eczema Encephalitis Eye/Vision Fatigue Fever Flu Food Poisoning Foot Gallbladder Gastrointestinal Genetic/Congenital GERD/Heartburn Hair Loss Hair/Scalp Headache Hearing Heart Disease, Stroke Heat/Sunstroke Hepatitis Hernia Herpes High Blood Pressure Hormonal Immune Disorders Immunizations/Vaccines Impotence Incontinence/Bladder Infections Injuries Kidney/Urinary Kids Learning Disabilities Liver Lung Cancer Men Menopause, Postmenopause Migraine Mobility/Balance Multiple Sclerosis Muscle Neural Nosebleeds Pain Parasites Pituitary PMS Pregnancy Prostate Cancer Prostate Disorders Psoriasis Psychological Raynaud's Disease Respiratory Reye Syndrome Rheumatoid Arthritis Schizophrenia Seniors Sensory Sexually Transmitted Disease Skin Sleep Speech Disorders Spinal Thyroid Trauma Weight Loss Women Yeast Infections Home Health Encyclopedia Keratoconus Keratoconus Injury Disease Nutrition Poison ... Prevention Keratoconus Definition: Keratoconus is a deterioration of the structure of the cornea with gradual bulging from the normal round shape to a cone shape. This condition causes

53. Keratoconus- Health Encyclopedia And Reference keratoconus Symptoms, Treatments and Medications. keratoconus is a progressiveectasia (expansion or dilatation) of the cornea, usually bilateral, http://www.healthcentral.com/encyclopedia/408/580/Keratoconus.html

Dr. Dean TV Specials Newsletters Help Apr 14, 2005 Home News Diseases Symptoms ... Health Tools Search Choose a Health Topic * All Health Topics * Acne Addictions AIDS/HIV Alcohol Abuse Allergies Alternative Medicine Alzheimer's Arthritis Asthma Attention Deficit Disorder (ADHD) Backache Bipolar Affective Disorder Birth Control Blood Blood Pressure Bone/Joint/Tendon Bowel Brain Breast cancer Cancer Cerebral Palsy Cholesterol Cramps Crohn's Disease Cysts Dental/Oral Depression Diabetes Diet, Fitness, Looks Disabled/Special Needs Drug Abuse Ear/Nose/Throat Eating/Appetite Eczema Encephalitis Eye/Vision Fatigue Fever Flu Food Poisoning Foot Gallbladder Gastrointestinal Genetic/Congenital GERD/Heartburn Hair Loss Hair/Scalp Headache Hearing Heart Disease, Stroke Heat/Sunstroke Hepatitis Hernia Herpes High Blood Pressure Hormonal Immune Disorders Immunizations/Vaccines Impotence Incontinence/Bladder Infections Injuries Kidney/Urinary Kids Learning Disabilities Liver Lung Cancer Men Menopause, Postmenopause Migraine Mobility/Balance Multiple Sclerosis Muscle Neural Nosebleeds Pain Parasites Pituitary PMS Pregnancy Prostate Cancer Prostate Disorders Psoriasis Psychological Raynaud's Disease Respiratory Reye Syndrome Rheumatoid Arthritis Schizophrenia Seniors Sensory Sexually Transmitted Skin Sleep Speech Disorders Spinal Thyroid Trauma Weight Loss Women Yeast Infections Home Miscellaneous Keratoconus Health Encyclopedia - Diseases and Conditions A B C D ... Y Keratoconus What is the Definition of Keratoconus?

54. Keratoconus: Definition, Symptoms, And Treatment - Kellogg Eye Center keratoconus defined, description of symptoms, and information on treatment http://www.kellogg.umich.edu/patientcare/conditions/keratoconus.html

About 120 million people in the U.S. wear eyeglasses or contact lenses to correct nearsightedness, farsightedness or astigmatism. Home Eye Conditions A-D E-M ... Ask the Expert Keratoconus Definition Symptoms Treatment Clinic Information Definition Keratoconus, meaning "cone shaped," describes a condition in which the cornea (the clear front window of the eye) becomes thin and protrudes. This abnormal shape can cause serious distortion of visual images. The cause of keratoconus is unknown. It usually appears in a patient during their late teens or early twenties. The disease slowly progresses for 10 to 20 years as the cornea steepens and scars. Although both eyes may be affected, one eye is usually worse than the other. Vigorous eye rubbing can add to the disease process, therefore patients with keratoconus are advised to avoid rubbing their eyes. Symptoms Frequent changing of glasses or contact lens prescriptions Blurring and distortion of vision Glare Light sensitivity and irritation Scarring of the cornea The symptoms described above may not necessarily mean that you have keratoconus. However, if you experience one or more of these symptoms, contact your eye doctor for a complete exam.

55. Keratoconus:AOA keratoconus is a vision disorder that occurs when the normally round cornea (thefront In its earliest stages, keratoconus causes slight blurring and http://www.aoa.org/x1790.xml

setrollover('images/btn-about-on.gif', 'about'); setrollover('images/btn-conditions-on.gif', 'conditions'); setrollover('images/btn-clincare-on.gif', 'clincare'); setrollover('images/btn-advocacy-on.gif', 'advocacy'); setrollover('images/btn-membership-on.gif', 'membership'); setrollover('images/btn-charities-on.gif', 'charities'); setrollover('images/btn-commcenter-on.gif', 'commcenter'); setrollover('images/btn-students-on.gif', 'students'); Keratoconus Eye Diseases Keratoconus is a vision disorder that occurs when the normally round cornea (the front part of the eye) becomes thin and irregular (cone) shaped. This abnormal shape prevents the light entering the eye from being focused correctly on the retina and causes distortion of vision. In its earliest stages, keratoconus causes slight blurring and distortion of vision and increased sensitivity to glare and light. These symptoms usually appear in the late teens or late twenties. Keratoconus may progress for 10-20 years and then slow in its progression. Each eye may be affected differently. As keratoconus progresses, the cornea bulges more and vision may become more distorted. In a small number of cases, the cornea will swell and cause a sudden and significant decrease in vision. The swelling occurs when the strain of the cornea's protruding cone-like shape causes a tiny crack to develop. The swelling may last for weeks or months as the crack heals and is gradually replaced by scar tissue. If this sudden swelling does occur, your doctor can prescribe eyedrops for temporary relief, but there are no medicines that can prevent the disorder from progressing.

56. Keratoconus, Cornea Transplant, Cornea, Genetic Eye Medical Institute, Los Angel keratoconus, Cornea Genetic Eye Medical Institute, Los Angeles, California. http://www.keratoconus.com/

Cornea-Genetic Eye Medical Institute Cedars-Sinai Mark Goodson Building Paris May 9,2005 Yaron S. Rabinowitz M.D., Only the 3 rd American in recent history gives keynote lecture at French Eye Society (second largest eye society in the world) click here to read more Dr. Rabinowitz lecturing at the French Eye Society Dr. Rabinowitz receiving an award at the French Eye Society Affiliated with the Medical Genetics Birth Defect Center at Cedars-Sinai Medical Center, Mark Goodson Building in Los Angeles, California, our clinic offers specialty consultation in cornea, refractive surgery (LASIK), and pediatric congenital diseases of the eye. Offices in Los Angeles, Santa Clarita and Lancaster. Cornea Genetic Eye Institute 444 S. San Vicente Blvd, Suite 1102 Los Angeles, CA 90048 Cedars-Sinai Mark Goodson Building Voice: 1-310-423-9640 Los Angeles Office Location Lancaster Office Location Santa Clarita Office Location About the Director ... How to Contact Us Last Update April 4, 2002

57. Keratoconus Genetics Research Program please note we are urgently looking for any patient with keratoconus who has atleast one brother or sister with keratoconus anywhere in the world. http://www.keratoconus.com/keratoco.htm

Affiliated Doctors Laser Vision Correction (LASIK) Corneal ... Rabinowitz Keratoconus Genetics Research Program Pediatric Cornea Eye Birth Defects ... Us Keratoconus Genetics Research Program * please note we are urgently looking for any patient with keratoconus who has at least one brother or sister with keratoconus anywhere in the world. If you are willing to participate in our study please email us and we will contact you* Program staff: Yaron S. Rabinowitz, M.D. , Principle Investigator, Cornea Specialist/Ophthalmic Geneticist, and Diana Remba , Research Coordinator. This study is funded in part by a grant from the National Eye Institutes of Health. Background Our Goal Benefits of Participation How to Participate ... Information / How to get answers to your Questions Background Keratoconus literally means a cone-shaped cornea. The cornea or window of the eye thins, resulting in progressive nearsightedness and astigmatism over time. The vast majority of patients with keratoconus can be visually corrected with special contact lenses. They may require many lens changes over a lifetime as the cornea is constantly changing. The corneal thinning may stop or progress at any age.

58. Moorfields Eye Hospital NHS Trust : Keratoconus Moorfields Eye Hospital is the leading centre for Ophthalmic care worldwide. http://www.moorfields.org.uk/EyeHealth/Otherconditions/Keratoconus

Home Eye Health For Patients For Health Professionals ... Enucleation Keratoconus Ptosis Uveitis What to do Anatomy of the eye ... Other conditions Keratoconus printable page Keratoconus The stretching of the cornea tends to progress but the rate varies. Sometimes one eye may be badly affected while the other eye may show very little sign of the condition. The cause of keratoconus is unknown. It may be associated with allergy or could have a genetic component. Keratoconus rarely appears in an individual until puberty or beyond. Although no one can be sure how far keratoconus will develop in an individual, the condition does not cause blindness. With the current treatment available, most people should be able to lead a normal lifestyle despite this condition. However, good vision may be difficult to maintain at times and contact lens tolerance varies. Treatment and further support and information Back to other conditions back to top Home ... Terms and Conditions

59. Keratoconus Research The Discovery Fund for Eye Research scientists are world leaders in the explanationof molecular and biochemical changes in keratoconus corneas. http://www.discoveryfund.com/keratoconus.html

Home Research Overview Macular Degeneration Diabetic Retinopathy Ocular Herpes Keratoconus Molecular Ophthalmology Refractive Laser Infants and Children Clinical Trials Our Scientists Keratoconus Eye cross sections showing normal and keratoconus corneas Keratoconus (KC) is a disease of the cornea , the transparent curved "windshield" of the eye. The word keratoconus is formed by the joining of two Greek words - kerato meaning cornea and konos , meaning cone. Keratoconus, or "conical cornea" means that the natural curvature of the normal cornea has changed to a cone-like bulge due to a thinning of the cornea. Scarring of the cornea often occurs. This affects vision, which may be blurred or distorted, or may produce a ripple effect. As the disease progresses the affected eyes become increasingly nearsighted (myopic). In its most advanced form functional vision can be destroyed. Searching For The Clue To Keratoconus "It's like Col. Mustard in the library with a wrench," said Discovery Fund scientist Donald Brown, Ph.D. "Much like the ever-popular board game, our efforts in keratoconus research are focused towards understanding what is responsible for this disorder and how it achieves the corneal thinning and distortion." Keratoconus is an eye condition in which the normally round dome-shaped cornea progressively thins causing a cone-like bulge to develop. This results in significant visual impairment. The cornea is the clear window of the eye and is responsible for focusing most of the light coming into the eye. If it is distorted, then the image people see is distorted and out of focus. Although the cornea appears to be one clear membrane, it is actually composed of three distinct layers of tissue, each with its own function.

60. Keratoconus: Diagnosis And Management keratoconus is characterized by progressive thinning and steepening of the keratoconus shows no gender predilection and is bilateral in over 90% of http://www.opt.pacificu.edu/ce/catalog/web013/course.htm

Keratoconus: Diagnosis and Management Dennis Burger, OD, FAAO Joseph P. Shovlin, OD, FAAO, Karla Zadnik, OD, PhD, FAAO The three year COPE certification for this course has expired so it can no longer be used to obtain CE credits. No representation is made that the information included in the course is still valid or correct. The course is presented for reader interest only. No examination is available for this course. Course List Home Contact Bibliography Exam Bios Introduction Etiology The proposed etiology of keratoconus includes biochemical and physical corneal tissue changes, but no one theory fully explains the clinical findings and associated ocular and non-ocular disorders. It is possible that keratoconus is an end result or final common pathway of many different clinical conditions. It has been found in association with hereditary predisposition, atopic disease, certain systemic disorders, and rigid contact lens wear. Corneal tissue change - whether in the stroma or the epithelium and its basement membrane - has long been proposed as the cause of keratoconus. Teng (13) originally proposed the epithelium as the primary site of abnormal tissue because the earliest histopathologic change occurs there. Now many researchers believe that the primary site is the stroma and that tissue change occurs because of destruction of stromal tissue by collagenase (14-16). If research can identify the ultrastructural or biochemical abnormality causing keratoconus, it may then be possible to intervene in the disease process to halt or even reverse its expression.

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