61. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Neurological_Disor Readers Digest Health A description of isaacs syndrome, its alternate names NORD isaacs syndrome - A general discussion, the synonyms and further http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Neurologica

@import "/styles/navbar.css"; @import "/styles/tabStyles.css"; Set home page Bookmark site Add search Latest News ... Email to friend Text Size A A A Front Page ... Muscle Diseases : Isaacs Syndrome Subtopics See Also: Health: Conditions and Diseases: Musculoskeletal Disorders Health: Conditions and Diseases: Neurological Disorders: Peripheral Nervous System Health: Conditions and Diseases: Rare Disorders Search Google: Isaacs Syndrome News Books Links ... Mayo Clinic Develops New Coma Measurement System (September 8, 2005) full story Nitric Oxide Could Extend Fertility (September 8, 2005) Biochemistry , an American Chemical Society journal. full story Flipped, Expelled, Copied, And Shrunk: Researchers Document Dramatic Genome Alterations During Primate Evolution (September 6, 2005) Genome Research presents a series of studies that provide insight into the evolution and variation of primate genomes. The issue will appear online and in print on September 1, concomitant with the publication of the chimpanzee genome sequence in the journal Nature full story Discovery Will Aid Identification Of Misregulated Genes In Rett Syndrome (September 4, 2005)

62. Neuromyotonia Continuous Muscle Fiber Activity syndrome; isaacs syndrome; Quantal Squander;isaacsMerten syndrome. Disorder Subdivisions. None. General Discussion http://my.webmd.com/hw/health_guide_atoz/nord758.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map You are in Medical Library Our Content Sources Ask A Question Clinical Trials Health Guide A-Z Health Topics Symptoms Medical Tests Medications ... For a Complete Report Neuromyotonia Important It is possible that the main title of the report Neuromyotonia is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Continuous Muscle Fiber Activity Syndrome Isaacs' Syndrome Quantal Squander Isaacs-Merten Syndrome Disorder Subdivisions None General Discussion Neuromyotonia is a rare neuromuscular disorder characterized by abnormal nerve impulses from the peripheral nerves. These impulses cause continuous muscle fiber activity that may continue, even during sleep. The disorder, which has both inherited and acquired forms, is characterized by muscular stiffness and cramping, particularly in the limbs. Continuous fine vibrating muscle movements (myokymia) can be seen. Muscle weakness may also be present. Muscle relaxation may be difficult especially after physical activity involving the particular muscle(s). Resources NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse

63. Index isaacsMerten syndrome Ischemic Necrosis of Bone Islet cell cancer Treatment -Patient Information Cancer.gov Isolated Vitamin E Deficiency http://my.webmd.com/hw/index/index-topics-I.asp

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64. Penn State Faculty Research Expertise Database (FRED) GamstorpWohlfart syndromes, Isaac syndrome. isaacs Mertens syndrome, isaacsPseudomyotonia syndrome. Myokymias, Continuous, Neuromyotonia, Acquired http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D020386

65. Internet Scientific Publications, LLC. We report two patients with isaacs syndrome (acquired neuromyotonia) who isaacs syndrome (IS) is characterized by spontaneously occurring muscle http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijn/vol1n2/issacs.xml

66. Dorlands Medical Dictionary (i¢zschwaks) H. isaacs, American neurologist, 20th century see under syndrome.isaacsMertens syndrome (I·saacs-Mer·tens syndrome) (i¢zschwaks http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszS

67. Health/Conditions And Diseases/Neurological Disorders/Muscle Diseases/Isaacs Syn A summary and general discussion about isaacs syndrome. A description ofisaacs syndrome, its alternate names and resources. http://www.thedoctorslounge.net/dir/Health/Conditions_and_Diseases/Neurological_

Advertisement Powered by Careerbuilder Search for: Home Humor Advertising Contact ... Links Specialties Cardiology Chest diseases Dermatology Endocrinology ... Urology Other Sections Membership Research Tools Medical Tutorials Medical Software ... Specialized Centers Headlines: The Medical Website Directory Popular Categories Popular Links Web Sites report abuse/spam url: report-abuse.dmoz.org/?cat=Health/Conditions_and_D... Baylor Neurology Case of the Month A summary and general discussion about Isaacs' syndrome. url: www.bcm.edu/neurol/challeng/pat2/summary.html NORD: Isaacs' Syndrome A general discussion, the synonyms and further resources. url: www.rarediseases.org/search/rdbdetail_abstract.htm... Readers Digest Health A description of Isaacs' syndrome, its alternate names and resources. url: www.readersdigesthealth.com/kbase/nord/nord758.htm mozilla.org url: www.mozilla.org/ Wikipedia url: en.wikipedia.org/ edit url: editors.dmoz.org/editors/editcat.cgi?cat=Health/Co... More Search All the Web AltaVista Gigablast Google USENET ... Yahoo In association with ODP Help build the largest human-edited directory on the web.

68. Dorlands Medical Dictionary isaacs syndrome, isaacsMertens syndrome, progressive muscle stiffness andspasms, with continuous muscle fiber activity similar to that seen with http://www.merckmedicus.com/pp/us/hcp/thcp_dorlands_content.jsp?pg=/ppdocs/us/co

69. Continuous Muscle Fiber Activity ISAACS, Journal Of Neurology, Neurosurgery And isaacs, H., A syndrome of continuous musclefibre activity. Tang, X., isaacssyndrome report of a Chinese case with clinical and electrophysiologic http://www.remarkablemedicine.com/Clinical/clinicaluses/neuromuscular/musclefibe

Your browser does not support script Buy the Books Written in Frustration and The Story of a Remarkable Medicine Continuous Muscle Fiber Activity Isaacs Journal of Neurology, Neurosurgery and Psychiatry describes the syndrome of continuous muscle fiber activity in two patients, marked by progressive muscle stiffness increased by voluntary muscle contractions and accompanied by fasciculation and weakness. Electromyography recorded a state of constant rapid dysrhythmic discharge of independent muscle fibers. The author defined the state as myotonic afterdischarge and likened it to post-tetanic afterdischarge. Neither patient showed response to numerous medications including quinidine, procainamide, cortisone, and atropine. Treatment with PHT (100 mg q.i.d.) resulted in dramatic improvement in symptoms and electromyographic changes both at rest and on voluntary effort. In a five-year follow-up, the author reported that both patients were still well and had lost their abnormal stiffness. He noted that on the occasions when PHT had been stopped, the symptoms returned. 176. Isaacs, H., A syndrome of continuous muscle-fibre activity.

70. British Library Direct: Order Details Order from the British Library A case of isaacs syndrome Neurologia INeurochirurgia Polska. http://direct.bl.uk/research/50/33/RN125486691.html

This is an article from British Library Direct, a new service that allows you to search across 20,000 journals for free and order full text using your credit card. Buy this article Search British Library Direct Return to Google Article details Article title Author Balcewicz, J. Kierkus, K. Journal title NEUROLOGIA I NEUROCHIRURGIA POLSKA Bibliographic details 2002, VOL 36; PART SUP 2; ISSU/2, pages 60 Publisher EFEKT Country of publication Poland ISBN ISSN Language Original Pricing To buy the full text of this article you pay: service charge Abstract: By using this site you agree to our terms and conditions Privacy policy We welcome your comments

71. Isaacs-Mertens Syndrome Information Diseases Database isaacsMertens syndrome, Disease Database Information. http://www.diseasesdatabase.com/ddb31529.htm

Diseases Database Index Sponsors Contact ... Previous Page Isaacs-Mertens syndrome information Search Isaacs-Mertens syndrome may cause or feature (Follow link for list.) belong(s) to the category of (Follow link for list.) Isaacs-Mertens syndrome: Definition(s) via UMLS Code translations and terms via UMLS Isaacs-Mertens syndrome: specific web sites Send Isaacs-Mertens syndrome to medical search engines (JavaScript enabled browsers only.) If your browser has no JavaScript you can still use these: Search using Internet medical databases Search using Internet search engines (non-specialist) We subscribe to the HONcode principles of the Health On the Net Foundation Valid XHTML 1.0 Served 2005-09-09 09:25:47 View metadata Last major update 2005-09-03. The medical information here is presented for education, background reading and general interest. The Diseases Database is not a diagnostic or clinical decision-making tool. Please consult your own licensed physician regarding diagnosis and treatment of any medical condition! Content is not asserted complete or error free, please see also our

72. Arch Neurol -- Abstract: Isaacs' Syndrome With Muscle Hypertrophy Reversed By Ph isaacs syndrome with muscle hypertrophy reversed by phenytoin therapy We suggest that the excess muscle activity in isaacs s syndrome may be http://archneur.ama-assn.org/cgi/content/abstract/40/4/241

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 40 No. 4, April 1983 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Zisfein J Bender AN Articles that cite this article Contact me when this article is cited Isaacs' syndrome with muscle hypertrophy reversed by phenytoin therapy J. Zisfein, M. Sivak, A. M. Aron and A. N. Bender A 16-year-old boy was seen for severe episodic muscle cramps and generalized myokymia, consistent with Isaacs's syndrome. Bilateral calf hypertrophy (46-cm calf circumference) and ankle areflexia were noted. He was treated with phenytoin sodium, 300 mg/day. Within three months there was marked decrease in myokymia, total relief of cramps, return of ankle

73. Arch Neurol -- Table Of Contents (Vol. 40 No. 4, April 1983) isaacs syndrome with muscle hypertrophy reversed by phenytoin therapy J. Zisfein;M. Sivak; AM Aron; AN Bender Arch Neurol. 1983;40241242. ABSTRACT http://archneur.ama-assn.org/content/vol40/issue4/index.dtl

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 40 No. 4, pp. 193-260, April 1983 Content Access Sign in/out Activate online subscription One-time access Individual subscriptions ... Register for E-mail Alerts Advertisement //This is the Right Skyscraper DisplayAds ("Right1,Position2!Right1", "120", "600"); //This is the Left Skyscraper DisplayAds ("Right1,Position2!Position2", "120", "240"); Table of Contents Jump to Section ARTICLES ARTICLES The pertussis vaccine controversy. The danger of case reports G. M. Fenichel Arch Neurol. Hemispheric specialization and the neurology of emotion D. M. Bear Arch Neurol. ABSTRACT A family with histologically confirmed Alzheimer's disease L. E. Nee; R. J. Polinsky; R. Eldridge; H. Weingartner; S. Smallberg; M. Ebert Arch Neurol. ABSTRACT Cyanotic congenital heart disease with suspected stroke. Should all patients receive antibiotics? R. Kurlan; R. C. Griggs

74. Journal Of Clinical Neuromuscular Disease - UserLogin isaacs H. A syndrome of continuous musclefiber activity. Systemic juvenilerheumatoid arthritis and associated isaacs syndrome. J Rheumatol. http://www.jcnmd.com/pt/re/jclnnmd/fulltext.00131402-200309000-00002.htm

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75. Journal Of Clinical Neuromuscular Disease - UserLogin 2729 In neuromyotonia (isaacs syndrome), rippling and twitching movements ofmuscle are isaacs H. A syndrome of continuous muscle-fibre activity. http://www.jcnmd.com/pt/re/jclnnmd/fulltext.00131402-200212000-00008.htm

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76. Continuous Muscle Fibre Activity: A Case Treated With Acetazolamide -- Çelebiso Continuous muscle fibre activity and the eponym isaacs syndrome describes a A 38 year old woman, who was diagnosed as having isaacs syndrome 12 years http://www.jnnp.com/cgi/content/full/64/2/256

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS Author Keyword(s) Vol Page [Advanced] This Article Abstract Full Text (PDF) Submit a response ... Citation Map Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation J Neurol Neurosurg Psychiatry 256-258 ( February ) Short report Continuous muscle fibre activity: a case treated with acetazolamide Ne soy, lu, Yaprak Akbaba, Ege University, Faculty of Medicine, Department of Neurology, Bornova, zmir, 35100, Turkey Correspondence to: Dr Ne zmir, 35100, Turkey. Telephone 00232 3880980; fax 00232 3422141. Received 14 May 1997 and in revised form 21 July 1997 Accepted 29 July 1997 Abstract Top Abstract Introduction Case report References A case is reported of the continuous muscle fibre activity syndrome, which includes a group of disorders characterised by sustained motor unit activity due to hyperactivity of peripheral nerve motor axons. In this patient the muscle stiffness and myokymic

77. Peripartum Management Of A Patient With Isaacs' Syndrome -- Morgan 44 (11): 1174 Peripartum management of a patient with isaacs syndrome She had a historyof isaacs syndrome (a peripheral motor neuron disorder), congenital heart http://www.cja-jca.org/cgi/content/abstract/44/11/1174

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS This Article Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager PubMed PubMed Citation Articles by Morgan, P. J. ARTICLES Peripartum management of a patient with Isaacs' syndrome PJ Morgan Department of Anaesthesia, Mount Sinai Hospital, Ontario. PURPOSE: To describe the peripartum management of a patient with Isaacs' syndrome with specific reference to the anaesthetic implications of the disease process. Associated medical problems included obesity, pregnancy induced hypertension and a difficult airway. CLINICAL FEATURES: This 30-yr-old gravida V para woman presented to the anaesthesia consultation clinic at 37-wk gestation to discuss pain relief options for labour and delivery. She had a history of Isaacs' syndrome (a peripheral motor neuron disorder), congenital heart disease (ASD and VSD), treated Hashimotos

78. CJA -- Table Of Contents (November 1 1997, 44 [11]) PJ Morgan Peripartum management of a patient with isaacs syndrome Can J Anesth1997 44 11741177. Abstract. SM Linz, C Charbonnet, MS Mikhail, http://www.cja-jca.org/content/vol44/issue11/index.shtml

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH TABLE OF CONTENTS Receive this page by email each issue: [Sign up for eTOCs] Contents: November 1 1997, Volume 44, Issue 11 [Index by Author] Other Issues: Articles Find articles in this issue containing these words: [Search ALL Issues] To see an article , click its [Full Text] link. To review many abstracts , check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time , click its [Abstract] link. Articles: DR Bevan Neuromuscular relaxants1997 Can J Anesth 1997 44: 1135-1137. S Schiere, L van den Broek, JH Proost, B Molenbuur, and JM Wierda Comparison of vecuronium with ORG 9487 and their interaction Can J Anesth 1997 44: 1138-1143. [Abstract] J Demers-Pelletier, P Drolet, M Girard, and F Donati Comparison of rocuronium and d-tubocurarine for prevention of succinylcholine-induced fasciculations and myalgia Can J Anesth 1997 44: 1144-1147. [Abstract] A Fassoulaki, C Sarantopoulos, and C Derveniotis Physostigmine increases the dose of propofol required to induce anaesthesia Can J Anesth 1997 44: 1148-1151.

79. Autoimmune Disease - OhioHealth isaacs syndrome is a rare, incurable nerve and muscle disease. It s characterizedby abnormal nerve impulses from the peripheral nerves. http://www.ohiohealth.com/healthreference/reference/nav-10236.htm

Home All Health Reference Condition Guides Healthy Living ... Immune System Autoimmune Disease Anti-phospholipid antibody syndrome Anti-phospholipid antibody syndrome is a rare immune system disorder due to abnormal proteins in the blood called anti-phospholipid antibodies. These interfere with the normal function of blood vessels. Autoimmune hepatitis Autoimmune hepatitis is a disorder in which the immune system attacks the liver, causing chronic inflammation of the liver. Bullous pemphigoid Bullous pemphigoid is a rare blistering disease of the skin. It causes large, firm, water-filled blisters (bullae) that affect multiple areas of the skin. Isaacs' syndrome Isaacs' syndrome is a rare, incurable nerve and muscle disease. It's characterized by abnormal nerve impulses from the peripheral nerves. These impulses cause continuous activity in muscle fibers (motor neurons). Islet cell transplantation: The diabetes treatment frontier Some people with type 1 diabetes (formerly called insulin-dependent or juvenile diabetes) can say goodbye to needles with the help of donated insulin-producing cells. Mixed connective tissue disease Mixed connective tissue disease (MCTD) is a rare autoimmune disorder. It's traditionally considered an "overlap" syndrome with signs and symptoms of lupus, scleroderma and polymyositis.

80. Birth Disorder Information Directory - I isaacs (Mertens) syndrome (Continuous Muscle Fiber Activity, Hereditary).isaacs syndrome Continuous muscle fiber activity hereditary http://www.bdid.com/defecti.htm

HOME I I-Cell Disease (Mucolipidosis, Type II) List of Sites ICE Syndrome (Ichthyosis-Cheek-Eyebrow Syndrome, Sidransky Feinstein Goodman Syndrome) ICHTHYOSISCHEEKEYEBROW SYNDROME ICF Syndrome See Centromeric Instability Immunodeficiency Syndrome Ichthyosiform/Ichthyosis List of Sites -Alopecia-Eclabion-Ectropion-Mental Retardation Syndrome ICHTHYOSIS WITH ALOPECIA, ECLABION, ECTROPION, AND MENTAL RETARDATION -Camptodactyly Syndrome See Camptodactyly-Ichthyosis Syndrome -Cheek-Eyebrow Syndrome See ICE Syndrome -Hepatosplenomegaly-Cerebellar Degeneration Syndrome ICHTHYOSIS, HEPATOSPLENOMEGALY, AND CEREBELLAR DEGENERATION -Spastic Neurologic Disorder-Oligophrenia Syndrome See Sjogren-Larsson Syndrome with Large Keratohyalin Granules in the Skin ICHTHYOSIS-MENTAL RETARDATION SYNDROME WITH LARGE KERATOHYALIN GRANULES IN THE SKIN Erythroderma -Corneal Involvement-Deafness Syndrome See KID Syndrome Congenital (Brocq) Also see Netherton Syndrome Bullous Form (Epidermolytic Hyperkeratosis) Bullous ichtyosiform erythroderma congenita BULLOUS ERYTHRODERMA ICHTHYOSIFORMIS CONGENITA OF BROCQ Nonbullous Form Type 1 (Nonbullous Congenital Ichthyosiform Erythroderma, Type I)

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