61. Www.nycomed.com - Orthostatic Hypotension What is orthostatic hypotension? Orthostatic hypotension is a sudden fall in blood pressure that typ. http://www.nycomed.com/en/Menu/Products/Hypotension.htm

Home Sitemap Contact Downloads Entire site Partnering Investors Products Markets People Media About us Partnering Investors Products Markets ... Product contacts Orthostatic Hypotension Print Send What is orthostatic hypotension? Orthostatic hypotension is a sudden fall in blood pressure that typically occurs when a person assumes a standing position. Signs of low blood pressure Low blood pressure may be caused by low blood volume resulting from the use of certain types of medications, dehydration, or prolonged bed rest. The disorder may be associated with atherosclerosis (build-up of fatty deposits in the arteries), diabetes, and certain neurological disorders including Shy-Drager syndrome. The drop in blood pressure causes inadequate blood flow to the brain, heart and other vital organs.  Symptoms, which generally occur after sudden standing, range from dizziness and lightheadedness to more severe consequences of falls, fractures, and immobility. Effective treatment for chronic low blood pressure The most prominent effects of midodrine hydrochloride are on the cardiovascular system, consisting of a rise in systolic and diastolic blood pressures. The increase in blood pressure is due almost entirely to an increase in peripheral resistance. Midodrine hydrochloride tablets may be added to an established treatment regimen in order to reduce symptoms in the primary neurogenic types of idiopathic orthostatic hypotension such as those present in the Bradbury-Eggleston or Shy-Drager syndromes.

62. Hypotension - Enpsychlopedia Reduced blood volume, called hypovolemia, can also cause hypotension and often results from It uses material from the Wikipedia article hypotension . http://psychcentral.com/psypsych/Hypotension

home resource directory disorders quizzes ... support forums Hypotension In physiology and medicine hypotension refers to an abnormally low blood pressure . It is often associated with shock , though not necessarily indicative of it. Contents showTocToggle("show","hide") 1 Causes 2 Indicators 3 Symptoms 4 References ... edit Causes Orthostatic hypotension is a common cause of low blood pressure , resulting from a sudden change in body position. Reduced blood volume, called hypovolemia , can also cause hypotension and often results from the use of diuretics or vasodilators such as nitric oxide or furosemide edit Indicators For most individuals, a healthy blood pressure lies between 90/60 mmHg to 130/80 mmHg. A small drop in blood pressure, even as little as 20 mmHg, can result in transient hypotension. edit Symptoms Low blood pressure is often accompanied by: Chest pain Shortness of breath Irregular heartbeat Fever F C ... Headache Stiff neck Severe upper back pain Cough with phlegm Prolonged diarrhea or vomiting Inability to eat or drink Burning with urination Foul-smelling urine edit References Hypovolemia - MedLine Plus http://www.nlm.nih.gov/medlineplus/ency/article/003083.htm

63. Baylor Neurology Case Of The Month In some patients with longstanding CSF hypotension there is also fibrosis of the meningies. Whatever the specific cause, most authors agree that the http://www.bcm.edu/neurology/challeng/pat28/summary.html

Patient #28 Summary and Discussion Jay Foreman, M.D., Ph.D. Resident, Department of Neurology Diagnosis: 1. Spontaneous intracranial hypotension 2. Secondary Arnold-Chiari Malformation The most worrisome and confusing aspects of this case, however, were the findings of CSF pleocytosis and diffuse meningeal enhancement on MRI ( see initial MRI ). In fact, the patient was referred to our service for a possible meningeal biopsy because of the unexplained nature of her problem and these MRI findings. The numerous possibilities of diffuse meningeal enhancement include inflammatory, infectious, and neoplastic processes. Meningeal enhancement is seen with meningeal carcinomatosis and lymphoma but the appearance is usually one of nodular enhancement, which may be focal or diffuse. Our patient had no evidence of blood cell dyscrasia on peripheral smear. Additionally this patient had no other symptoms or laboratory findings to suggest the presence of a malignancy. Neurosarcoidosis can give a similar appearance but it is usually associated with cranial neuropathy (53%), parenchymal disease (48%), aseptic meningitis (22%), peripheral neuropathy (17%), myopathy (15%) and/or hydrocephalus (7%). There is usually some evidence of systemic disease (97%) and elevation of serum angiotensin enzyme (ACE) levels. None of these were present in our patient. Lyme disease was considered. There is a triad of meningitis, radiculitis and neuritis without fever that is highly suggestive of this disease. Meningeal enhancement may or may not be seen, but is more often at nerve roots. Initially, patients have mild meningeal signs including headaches, myalgias, stiff neck and cranial nerve involvement. After several weeks patients may have cardiac conduction abnormalities, meningial signs, multiple cranial neuropathies, peripheral mononeuropathies and encephalopathy, as well as transitory erythematous blotchy rashes. The third stage typically involves development of a chronic arthritis. Our patient had none of these findings and her Lyme titers were negative.

64. Hypotension - Definition From Biology-Online.org Definition and other additional information on hypotension from BiologyOnline.org dictionary. http://www.biology-online.org/dictionary/hypotension

Forum Tutorials Dictionary Directory ... H hypotension hypotension (Science: cardiology, physiology) Abnormally low blood pressure , seen in shock but not necessarily indicative of it. Search the dictionary About Us Contact Us Link to Us Chemistry ... Equations

65. TRAUMA.ORG: Permissive Hypotension TRAUMA.ORG Permissive hypotension and Lowvolume Resuscitation - A Bibliography. http://www.trauma.org/resus/permissivehypotension.html

EDITORIAL LIST DISCUSSION RESUSCITATION TRAUMA-LIST ARCHIVES Permissive Hypotension Barry Armstrong, trauma.org 7:10, October 2002 Barry Armstrong General Surgeon - Dryden, Ontario, Canada Bibliography Understanding permissive hypotension in trauma care Permissive hypotension is a hot topic in trauma circles. In the late 20th century, the early care for an injured person included “2 large-bore Intravenous lines, running wide open”. The current trend, in ambulances and emergency rooms, is to limit fluid resuscitation, at least until hemorrhage is controlled by natural hemostasis, external pressure, angiography or surgery. Metaphorically, the tide of fluid resuscitation is ebbing; our bleeding patients are managed drier than previously. Editorial - Permissive Hypotension Ken Mattox Trauma-List discussion of Permissive Hypotension in Trauma Resuscitation About the bibliography To help you understand why the tide has turned, these references include abstracts, plus access to some full text articles. Text in

66. TRAUMA.ORG: Permissive Hypotension TRAUMA.ORG Permissive hypotension and Lowvolume Resuscitation - The Trauma-List Discussion. http://www.trauma.org/archives/permhypo.html

ARCHIVES TRAUMA-LIST EDITORIAL BIBLIOGRAPHY ... RESUSCITATION Permissive Hypotension for Trauma Resuscitation compiled by Jon Hoerner trauma.org (7:10) October 2002 Please mark my word. Within no less than 10 years, probably even less than 5 years, any [one] that raises the blood pressure to higher than 3/4 the pre injury level, especially if using crystalloid solutions will be severely criticized as violating one of the indicators, whether the injury be penetrating, blunt, elderly, child, or one's own self or family. Also mark this down on this date. The final target for a prehospital or EC measured BP will be that greater than 80 SYSTOLIC will be the level that the QA moral police will cite that those of you who believe in two large bore IVs, Rapid infusors, interosseous and sternal infursors, the 3 to 1 rule, and cyclic hyper resuscitation as causing unnecessary complications, deaths, and costs. Ken Mattox.

67. Clinical Trial: Droxidopa In Treating Patients With Neurogenic Hypotension RATIONALE Neurogenic hypotension is a fall in blood pressure that occurs when Neurogenic hypotension is caused by a problem in the part of the nervous http://www.clinicaltrials.gov/ct/show/NCT00004478

Home Search Browse Resources ... About Droxidopa in Treating Patients With Neurogenic Hypotension This study has been suspended. Verified by Office of Rare Diseases (ORD) September 2005 Sponsored by: Mount Sinai School of Medicine Information provided by: Office of Rare Diseases (ORD) ClinicalTrials.gov Identifier: Purpose RATIONALE: Neurogenic hypotension is a fall in blood pressure that occurs when one moves from a lying down to a standing position or after eating a meal. It causes one to feel dizzy, light headed, and weak. Neurogenic hypotension is caused by a problem in the part of the nervous system that controls such functions as heart rate and blood pressure. Droxidopa, a drug that may increase blood pressure, may be an effective treatment for neurogenic hypotension. PURPOSE: Clinical trial to study the effectiveness of droxidopa in treating patients who have neurogenic hypotension. Condition Intervention Shy-Drager Syndrome Orthostatic Hypotension Drug: droxidopa MedlinePlus related topics: Degenerative Nerve Diseases Low Blood Pressure Study Type: Interventional Study Design: Treatment Official Title: Study of Droxidopa in Patients with Neurologic Hypotension Further Study Details: Study start: March 1999 PROTOCOL OUTLINE: Patients receive escalating doses of droxidopa or placebo for 7-14 days. Patients undergo blood pressure measurements hourly in both supine and standing positions.

68. Clinical Trial: Efficacy Of Therapeutic Interventions For Orthostatic Hypotensio Orthostatic hypotension, Drug Fludrocortisone Drug Domperidone Behavior Conservative Measures for Orthostatic hypotension http://www.clinicaltrials.gov/ct/show/NCT00103597

Home Search Browse Resources ... About Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy This study is currently recruiting patients. Verified by Royal Brisbane and Women's Hospital July 2005 Sponsored by: Royal Brisbane and Women's Hospital Information provided by: Royal Brisbane and Women's Hospital ClinicalTrials.gov Identifier: Purpose Patients with Parkinson's Disease or Multiple System Atrophy (MSA), and symptoms of orthostatic hypotension, are eligible for the study. Each patient will have three weeks of conservative therapy, three weeks of therapy with fludrocortisone, and three weeks of therapy with domperidone. Autonomic testing, a symptom questionnaire, bedside blood pressure testing, and Unified Parkinson Disease Rating Scale (UPDRS) will be performed after each intervention. Condition Intervention Phase Parkinson's Disease Multiple System Atrophy Orthostatic Hypotension Drug: Fludrocortisone Drug: Domperidone Behavior: Conservative Measures for Orthostatic Hypotension Phase I MedlinePlus related topics: Brain Diseases Degenerative Nerve Diseases Low Blood Pressure Movement Disorders ... Genetics Home Reference related topics: Parkinson disease Study Type: Interventional Study Design: Treatment, Randomized, Double-Blind, Uncontrolled, Crossover Assignment, Efficacy Study

69. Hypotension, Orthostatic Orthostatic hypotension (OH) describes an extreme drop in blood pressure that may occur when a person stands up suddenly and the blood pools in the blood http://www.bchealthguide.org/kbase/nord/nord769.htm

var hwPrint=1;var hwDocHWID="nord769";var hwDocTitle="Hypotension, Orthostatic";var hwRank="1";var hwSectionHWID="nord769-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Hypotension, Orthostatic Important It is possible that the main title of the report Hypotension, Orthostatic is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Postural Hypotension Disorder Subdivisions None General Discussion Orthostatic Hypotension (OH) describes an extreme drop in blood pressure that may occur when a person stands up suddenly and the blood pools in the blood vessels of the legs. Because of this pooling, the amount of blood carried back to the heart by the veins is decreased. Subsequently, less blood is pumped out from the heart, resulting in a sudden drop in blood pressure. By definition, the drop in blood pressure must be greater than 20 mm of mercury during contraction of the heart muscles (systole) and more than 10 mm of mercury during expansion of the heart muscles (diastole). Among children and teenagers, short-lived episodes of OH are normal and not uncommon. Episodes among the elderly are always to be taken seriously. Normally, specialized cells in the body (baroreceptors) quickly respond to changes in blood pressure. These baroreceptors then activate the autonomic nervous system to increase, via reflex action, levels of catecholamines (e.g. epinephrine, norepinephrine) in the body. Increased catecholamine levels rapidly restore the blood pressure. A defect in this spontaneous response (reflex), prevents the heart rate and blood pressure from rising adequately and orthostatic hypotension results. Fainting and falling are the usual consequences.

70. HighWire -- Browse Journals - Ocular Hypotension Browse Journals publishing on Ocular hypotension, (return to Topic List page) Alphabet, , Frequency of articles in Ocular hypotension http://highwire.stanford.edu/lists/topic_dir/608683/608684/617096/617097/617218/

ANNOUNCEMENT: CHECK OUT THE PREVIEW RELEASE OF OUR NEW WEB SITE! My Favorite Journals ( HW-hosted journals HW-hosted Medline Author: Keyword(s): Year: Vol: Page: Home Adv. Search For Institutions For Publishers ... Sign in or register for access to all HighWire Press customization features Browse Journals publishing on Ocular Hypotension: (return to Topic List page) Ocular Hypotension Sort by: Alphabet Frequency of articles in Ocular Hypotension Focus of journal on Ocular Hypotension What's this? Journals focusing on Ocular Hypotension (in order by highest focus) Journal of Pharmacology and Experimental Therapeutics info free ISSUES Annals of the New York Academy of Sciences ... Eye Diseases Ocular Hypotension Home Adv. Search For Institutions For Publishers ... partners/suppliers

71. BBC - Health - Ask The Doctor - Hypotension And Blackouts Waking up with a low blood sugar can aggravate hypotension and may be the Older people with postural hypotension are often advised to wear support http://www.bbc.co.uk/health/ask_the_doctor/hypotensionblackouts.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index FRIDAY 9th September 2005 Text only BBC Homepage Lifestyle Health ... Help Like this page? Send it to a friend! Hypotension blackouts Every time I get up I seem to black out. I can normally keep it under control, but lately it's made me collapse. Is this anything I should be worried about or is it normal? Deborah, 19 Dr Trisha Macnair responds The most likely cause of your blackouts is a condition called postural hypotension. When you go from lying down to standing up, your blood pressure drops very low, probably because your nervous system is a bit slow in telling your heart and blood vessels to work harder to counter the effects of gravity. When this happens, not enough blood reaches your brain causing you to feel faint and collapse. This is usually harmless, although if you fall there's the risk that you may hurt yourself; older people sometimes break their bones this way. In the rest of Europe, low blood pressure is taken seriously; it's often linked to a variety of symptoms and is frequently treated with drugs. In the UK, however, we tend to think that generally it's healthy to have a low blood pressure, so it's rarely treated. However, you should still see your doctor because very occasionally there are other causes for blackouts, although these are rare in young people. It's important that your doctor checks your blood pressure and makes sure of the diagnosis.

72. Orthostatic Hypotension - Swedish Medical Center, Seattle, Washington Orthostatic hypotension Swedish Medical Center, Seattle, Washington. http://www.swedish.org/14456.cfm

PDF Version Search Send-to-Friend Health Library Home ... Conditions InBrief Orthostatic Hypotension (Postural Hypotension) by Diane Voyatzis, RD Definition Causes Risk Factors ... Prevention Definition Orthostatic hypotension is a condition of abnormal blood pressure regulation upon standing. The blood pressure dramatically decreases (more than 20/10 mm Hg) when rising from a lying down or sitting position to a standing position. Measuring of Blood Pressure www.nucleusinc.com Causes Orthostatic hypotension has several causes. Hypovolemia is the most common cause. It may be due to: Excessive use of loop diuretic medications (furosemide, bumetanide, ethacrynic acid) Vasodilator medications (nitrate preparations, Ca blockers, or ACE inhibitors) Dehydration Prolonged bed rest Addisons disease (with inadequate salt intake) Impaired autonomic (nerve) reflex due to certain diseases: Diabetes Pernicious anemia Amyloidosis Guillain-Barre syndrome Riley-Day syndrome Shy-Drager syndrome Decreased heart muscle contractility or vascular responsiveness Certain drugs: Monoamine oxidase inhibitors (MAO inhibitors) (isocarboxazid, phenelzine, tranylcypromine)

73. Hypotension Patient information about low blood pressure (hypotension) from the NHS direct online These include an introduction to hypotension, followed by separate http://omni.ac.uk/browse/mesh/D007022.html

low graphics Hypotension broader: Vascular Diseases other: Aneurysm Angioneurotic Edema Arteriovenous Malformations Cerebrovascular Disorders ... Vasculitis narrower: Hypotension, Orthostatic NHS direct online health encylopaedia : blood pressure (low) Patient information about low blood pressure (hypotension) from the NHS direct online service. The pages contain comprehensive, clearly and simply written information covering different aspects of the condition. These include an introduction to hypotension, followed by separate sections on symptoms, causes, diagnosis and treatment. NHS direct online is a Web site providing high quality health information and advice for people in England. Patient Education Hypotension Blood Pressure Last modified: 09 Sep 2005

74. Orthostatic Hypotension In Women: Low Blood Pressure Many women experience what is called orthostatic hypotension or prostural hypotension. Therefore, a person with orthostatic hypotension may experience http://www.estronaut.com/a/orthostatic_hypotension_low_blood_pressure_women.htm

Orthostatic Hypotension in Women: Low Blood Pressure What is Orthostatic Hypotension? Gender Differences in Orthostatic Hypotension Orthostatic hypotension primarily affects women. There are also gender differences in the blood pressure to the brain, as well as the body. The brain has additional mechanisms for regulating blood pressure. Woman may experience classic orthostatic hypotension symptoms, but not be diagnosed correctly by some doctors. Doctors in an office setting can only test for this by measuring blood pressure in lying down and then more upright positions and comparing the results. What You Can Do for Orthostatic Hypotension Some Orthostatic Hypotension is Caused By Medications Some medications used to treat other health problems can result in orthostatic hypotension. Two types of medication in particular are antidepressants and anti-hypertension medications. The popular Serotonin Re-uptake Inhibitor antidepressants (like Prozac and most other modern antidepressants) can induce hypotension, although they have less of an adverse effect than the previously used tricyclic antidepressants. Anti-hypertension medications are most often used for the elderly as blood pressure increases with age. Ironically, the use of these medications can sometimes swing blood pressure to the opposite extreme, resulting in hypotension. If you are taking any of these medication and are experiencing the symptoms of hypotension, you may want to talk to your doctor about switching to a different drug, a lower dose, or discontinuing use of the medication altogether.

75. Orthostatic Hypotension Orthostatic hypotension. (Postural hypotension). by Diane Voyatzis, RD. Definition. Orthostatic hypotension is a condition of abnormal blood pressure http://healthgate.partners.org/browsing/browseContent.asp?fileName=34315.xml&tit

76. UpToDate Mechanisms And Causes Of Orthostatic And Postprandial Hypotension Less frequently, orthostatic hypotension leads to angina or stroke. Symptoms of orthostatic hypotension vary in severity from mild to incapacitating; http://patients.uptodate.com/topic.asp?file=neuropat/2483

77. FIRSTConsult - Sdfdsf FIRSTConsult, Postural hypotension (Differential Diagnoses File). Published for medical students and primary healthcare providers by Elsevier. http://www.firstconsult.com/?action=view_article&id=1220171&type=122&bref=1

78. FIRSTConsult - Sdfdsf FIRSTConsult, Orthostatic hypotension (Medical Condition File). Published for medical students and primary healthcare providers by Elsevier. http://www.firstconsult.com/?action=view_article&id=1014234&type=101&bref=1

79. Ae intracranial hypotension, dural fibrosis, sarcoid, TB, mets. Discussion The dural findings seen with intracranial hypotension are due to congestive changes http://www.med.uc.edu/neurorad/webpage/gba.html

Intracranial Hypotension Findings: Smooth, uniformly thickened and enhancing dura. Differential Diagnosis: intracranial hypotension, dural fibrosis, sarcoid, TB, mets Discussion: The dural findings seen with intracranial hypotension are due to congestive changes caused by chronically low intracranial pressure. The pressure differential may be maintained by an occult CSF leak, and many patients can give a history of previous lumbar puncture or trauma. Uniform thickening of the dura is a characteristic feature, and the lack of nodularity or a basilar distribution can help distinguish this process from metastatic disease or TB/sarcoid. The cerebellar tonsils may occasionally sink through the foramen magnum, leading to an acquired Chiari I malformation. BACK TO UNKNOWNS BACK TO CATEGORIES HOME NEXT CASE

80. Neurologists Have Discovered A Drug Application Smart Enough To Alleviate Orthos ? Mayo Clinic neurologists have discovered a drug application smart enough to alleviate orthostatic hypotension problems with sinking blood pressure http://www.news-medical.net/?id=5300

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