Home Health Information Health Topics A to Z Health Topics A to Z Diabetes Panhypopituitarism In some cases, the production of all of the pituitary hormones decreases or stops, usually due to damage to the entire pituitary gland. This condition is called panhypopituitarism. What is hypopituitarism? Hypopituitarism, also called an underactive pituitary gland, is a condition that affects the anterior (front) lobe of the pituitary gland - usually resulting in a partial or complete loss of functioning of that lobe. The resulting symptoms depend on which hormones are no longer being produced by the gland. Because the pituitary gland affects the other endocrine organs, effects of hypopituitarism may be gradual, or sudden and dramatic. What causes hypopituitarism? Hypopituitarism, in children, is often caused by a benign (non-cancerous) pituitary tumor, an injury, or an infection. However, often no exact cause can be determined. What are the symptoms of hypopituitarism? Symptoms vary depending on what hormones are insufficiently produced by the pituitary gland. The following are common symptoms associated with reduced production of certain hormones: insufficient gonadotropins production (luteinizing hormone and follicle-stimulating hormone) In premenopausal women, this leads to absent menstrual cycles, infertility, vaginal dryness, and loss of some female characteristics. In men, this deficiency leads to impotence, shriveling of testes, decreased sperm production, infertility, and loss of some male characteristics. | |
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