1. MedlinePlus Medical Encyclopedia: Hypopituitarism Find illustrations, alternative names, causes, symptoms, treatment, prognosis, complications, and prevention. http://www.nlm.nih.gov/medlineplus/ency/article/000343.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Hypopituitarism Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Endocrine glands The pituitary gland Pituitary hormones Pituitary and TSH Alternative names Return to top Pituitary insufficiency Definition Return to top Hypopituitarism is a condition caused by low levels of pituitary hormones. Causes, incidence, and risk factors Return to top The pituitary gland is a small structure that is located just below the brain. It is attached by a stalk to the hypothalamus , the area of the brain that controls its function. The hormones secreted by the pituitary and their functions are: growth hormone (GH), which stimulates growth of tissues and bone thyroid stimulating hormone (TSH), which stimulates the thyroid gland to secrete hormones that affect body metabolism adrenocorticotropic hormone (ACTH), which stimulates the adrenal gland to secrete cortisol which helps to maintain blood pressure prolactin , which stimulates female breast development and milk production luteinizing hormone (LH), which controls sexual function in males and females

2. What Is Hypopituitarism? - Endocrinology Health Guide Describes this condition, symptoms, causes, how it's diagnosed, and treated. http://www.umm.edu/endocrin/hypopit.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Endocrinology Health Guide... Pituitary Gland Disorders... Pituitary Tumors Acromegaly ... Glossary Related Resources Within UMM Endocrinology Joslin Diabetes Center School of Medicine Endocrinology Site Translate using Google to Spanish German French Italian Portuguese Endocrinology Health Guide Hypopituitarism What is hypopituitarism? Hypopituitarism, also called an underactive pituitary gland, is a condition that affects the anterior lobe of the pituitary gland usually resulting in a partial or complete loss of functioning of that lobe. The resulting symptoms depend on which hormones are no longer being produced by the gland. Because the pituitary gland affects the other endocrine organs, effects of hypopituitarism may be gradual or sudden and dramatic. What are the symptoms of hypopituitarism? Symptoms vary depending on what hormones are insufficiently produced by the pituitary gland. The following are common symptoms associated with reduced production of certain hormones: insufficient gonadotropins production (luteinizing hormone and follicle-stimulating hormone) In premenopausal women, this leads to absent menstrual cycles, infertility, vaginal dryness, and loss of some female characteristics. In men, this deficiency leads to impotence, shriveling of testes, decreased sperm production, infertility, and loss of some male characteristics.

3. EMedicine Health - Hypopituitarism In Children Overview Consumer health resource center providing information on the causes, symptoms, and treatment. From eMedicine. http://www.emedicinehealth.com/articles/35253-1.asp

Search September 9, 2005 Registration Healthcare Professionals You are in: Endocrine System Hypopituitarism in Children Hypopituitarism in Children Overview Hypopituitarism is a condition in which the pituitary gland (a small gland at the base of the brain) does not produce one or more of its hormones or not enough of them. This condition may occur because of disease in the pituitary gland or hypothalamus (a part of the brain that contains hormones that control the pituitary gland). When there is low or no production of all the pituitary hormones, the condition is called panhypopituitarism. Hypopituitarism can occur in children or adults. The pituitary gland produces several hormones. Adrenocorticotropic hormone (ACTH) is a hormone that stimulates the adrenal glands (glands on the kidneys that produce hormones). ACTH triggers the adrenal glands to release hormones called corticosteroids, such as cortisol, which regulates many aspects of metabolism, immune function, and blood pressure. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are hormones that control sexual function in males and females. They are also known as gonadotropins and help to control the production of the sex hormones, such as estrogen and testosterone, as well as egg and sperm production.

4. What Is Hypopituitarism? - Endocrinology Health Guide Health guide on hypopituitarism, also called an underactive pituitary gland. Definitions, causes, symptoms and treatments are discussed http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. MedlinePlus Medical Encyclopedia Hypopituitarism hypopituitarism is a condition caused by low levels of pituitary hormones. Causes, incidence, and risk factors Return to top http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. ► Hypopituitarism A medical encycopedia article on the topic hypopituitarism. http://www.umm.edu/ency/article/000343.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Disease Nutrition Surgery Symptoms Injury ... Encyclopedia (English) Toggle English Spanish Hypopituitarism Overview Symptoms Treatment Prevention Definition: Hypopituitarism is a condition caused by low levels of pituitary hormones. Alternative Names: Pituitary insufficiency Causes, incidence, and risk factors: The pituitary gland is a small structure that is located just below the brain. It is attached by a stalk to the hypothalamus , the area of the brain that controls its function. The hormones secreted by the pituitary and their functions are: growth hormone (GH), which stimulates growth of tissues and bone thyroid stimulating hormone (TSH), which stimulates the thyroid gland to secrete hormones that affect body metabolism adrenocorticotropic hormone (ACTH), which stimulates the adrenal gland to secrete cortisol which helps to maintain blood pressure prolactin , which stimulates female breast development and milk production luteinizing hormone (LH), which controls sexual function in males and females follicle stimulating hormone (FSH), which controls sexual function in males and females

7. HealthSouth: Healthcare In Surgery, Ambulatory, Diagnostic And Rehab A look at the treatment, prognosis and complications of this disease. http://www.healthsouth.com/medinfo/home/app/frame?2=/medlib/medLibDispatcher&

8. Postgraduate Medicine Endocrine Problems Symposium How To How to diagnose hypopituitarism http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. EMedicine - Hypopituitarism : Article By Stuart A Brilliant, MD hypopituitarism ED physicians have the opportunity to see patients who have been diagnosed with, or are being worked up for, hypopituitarism. http://www.emedicine.com/emerg/topic277.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Emergency Medicine Endocrine And Metabolic Hypopituitarism Last Updated: August 16, 2004 Rate this Article Email to a Colleague AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Stuart A Brilliant, MD , Staff Physician, Department of Emergency Medicine, University of Connecticut Editor(s): Robin R Hemphill, MD , Associate Program Director, Assistant Professor, Department of Emergency Medicine, Vanderbilt University; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, eMedicine; Howard A Bessen, MD , Program Director, Professor of Medicine, Department of Emergency Medicine, Harbor-UCLA Medical Center; John Halamka, MD , Chief Information Officer, CareGroup Healthcare System, Assistant Professor of Medicine, Department of Emergency Medicine, Beth Israel Deaconess Medical Center; Assistant Professor of Medicine, Harvard Medical School; and Craig Feied, MD, FACEP, FAAEM, FACPh

10. A Homozygous Mutation In HESX1 Is Associated With Evolving A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressorcorepressor interaction http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. EMedicine - Hypopituitarism (Panhypopituitarism) : Article By James R Mulinda, M hypopituitarism (Panhypopituitarism) hypopituitarism is a clinical syndrome of deficiency in pituitary hormone production. This may result from disorders http://www.emedicine.com/MED/topic1137.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Endocrinology Hypopituitarism (Panhypopituitarism) Last Updated: November 19, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: pituitary gland, hypothalamus, panhypopituitarism, pituitary insufficiency, adrenocorticotropic hormone, ACTH, corticotropin, follicle-stimulating hormone, FSH, luteinizing hormone, LH, growth hormone, GH, prolactin, thyroid-stimulating hormone, TSH, thyrotropin, antidiuretic hormone, ADH AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: James R Mulinda, MD, FACP, FACE , Consulting Staff, Chief, Section of Endocrinology, Clinical Assistant Professor of Medicine, Department of Internal Medicine, Section of Endocrinology, Pennsylvania Hospital, University of Pennsylvania James R Mulinda, MD, FACP, FACE, is a member of the following medical societies:

12. A Homozygous Mutation In HESX1 Is Associated With Evolving A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressorcorepressor interaction http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Pituitary Network Association - Disorders - Hypopituitarism hypopituitarism is a general term that refers to any under function of the Causes of hypopituitarism. Deficient pituitary gland function can result from http://www.pituitary.com/disorders/hypopituitarism.aspx

Specialty Endocrinologists Pediatric Endocrinologists Reproductive Endocrinologists Neurosurgeons Pediatric Neurosurgeons Skull Base Surgeons Radiation Oncologists Pathologists Hypopituitarism Hypopituitarism is a general term that refers to any under function of the pituitary gland. This is a clinical definition used by endocrinologists and is interpreted to mean that one or more functions of the pituitary are deficient. The term may refer to both anterior and posterior pituitary gland failure. Causes of hypopituitarism Sheehan's Syndrome Sheehan's syndrome is a condition that may occur in a woman who has a severe uterine hemorrhage during childbirth. The resulting severe blood loss causes tissue death in her pituitary gland and leads to hypopituitarism following the birth. For more on this Sheehan's syndrome, please visit MedlinePlus on Sheehan's Syndrome Deficiency of ACTH and cortisol Deficiency of ACTH resulting in cortisol deficiency is the most dangerous and life threatening of the hormonal deficiency syndromes. With gradual onset of deficiency over days or weeks, symptoms are often vague and may include weight loss, fatigue, weakness, depression, apathy, nausea, vomiting, anorexia and hyperpigmentation. As the deficiency becomes more serious or has a more rapid onset, (Addisonian crisis) symptoms may include confusion, stupor, psychosis, abnormal electrolytes (low serum sodium, elevated serum potassium), and vascular collapse (low blood pressure and shock) which can be fatal. Treatment consists of cortisol administration or another similar steroid (like prednisone). For patients with acute adrenal insufficiency (Addisonian crisis), rapid intravenous administration of high dose steroids is essential to reverse the crisis.

14. Enhanced Repression By HESX1 As A Cause Of Hypopituitarism And Enhanced Repression by HESX1 as a Cause of hypopituitarism and Septooptic Dysplasia Ronald N. Cohen , Laurie E. Cohen , Diego Botero http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Hypopituitarism - MayoClinic.com In hypopituitarism, your pituitary gland produces too little — or none — of one or more hormones. Disruption of any number of routine body functions can http://www.mayoclinic.com/invoke.cfm?id=DS00479

16. Intense Sympathetic Nerve Activity In Adults With Hypopituitarism Intense Sympathetic Nerve Activity in Adults with hypopituitarism and Untreated Growth Hormone Deficiency1 Yrsa Bergmann Sverrisd ttir http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Postgraduate Medicine: Endocrine Problems Symposium: How To Diagnose Hypopituita In addition to discussing the causes of hypopituitarism, the authors of hypopituitarism encompasses an expanse of problems that can involve from one to http://www.postgradmed.com/issues/1998/07_98/schmidt.htm

How to diagnose hypopituitarism Learning the features of secondary hormonal deficiencies Diane N. Schmidt, MD; Kathleen Wallace, MD VOL 104 / NO 7 / JULY 1998 / POSTGRADUATE MEDICINE This page is best viewed with a browser that supports tables This is the third of three articles on endocrine disorders Preview : Various abnormalities of or trauma to the pituitary gland or hypothalamus can cause hypopituitarism. Resultant hormonal deficiencies may be partial and may take years to develop fully. Therefore, the clinical picture is often subtle and may include numerous manifestations, depending on the hormones involved and the patient's age at onset. In addition to discussing the causes of hypopituitarism, the authors of this article describe how to recognize and treat resulting hypothyroidism, adrenal insufficiency, hypogonadism, and growth-hormone deficiency. H ypopituitarism is deficiency of one or more anterior pituitary hormones, which results in insufficient stimulation and therefore insufficient hormonal output of the respective target glands. The target-gland dysfunction is referred to as secondary deficiency, indicating that the pituitary gland is the source of the problem. Unexpected laboratory results may be the first clue to hypopituitarism. Illustrative case report A 59-year-old woman was admitted because of an asthma exacerbation and was noted to have fatigue, generalized weakness, hoarseness, constipation, cold intolerance, facial and infraorbital puffiness, and dry, cool skin. She was obese, having had weight gain over the course of many years. On questioning, she reported experiencing excessive hemorrhaging during many of her 10 pregnancies, being unable to breast-feed any of her children, and having amenorrhea since the age of 28. On admission, she was taking only high-dose corticosteroids that had recently been prescribed for asthma. Her pulse was 88 beats per minute and her reflexes showed a delayed relaxation phase. There was no evidence of thyroid enlargement.

18. EMedicine - Hypopituitarism Article By Stuart A Brilliant, MD hypopituitarism ED physicians have the opportunity to see patients who have been diagnosed with, or are being worked up for, hypopituitarism. While http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. THE MERCK MANUAL--SECOND HOME EDITION, Hypopituitarism In Ch. 162, Pituitary Gla hypopituitarism is an underactive pituitary gland that results in hypopituitarism, an uncommon disorder, can be caused by a number of factors, http://www.merck.com/mmhe/sec13/ch162/ch162c.html

var externalLinkWarning = "The link you have selected will take you to a site outside Merck and The Merck Manuals.*n*nThe Merck Manuals do not review or control the content of any non-Merck site. The Merck Manuals do not endorse and are not responsible for the accuracy, content, practices, or standards of any non-Merck sources."; Search The Second Home Edition , Online Version Search Index A B C D ... Z Sections Accidents and Injuries Blood Disorders Bone, Joint, and Muscle Disorders Brain, Spinal Cord, and Nerve Disorders ... Women's Health Issues Resources Anatomical Drawings Multimedia Pronunciations Weights and Measures ... , Online Version Section Hormonal Disorders Chapter Pituitary Gland Disorders Topics Introduction Acromegaly and Gigantism Central Diabetes Insipidus Empty Sella Syndrome ... Galactorrhea Hypopituitarism Hypopituitarism Buy The Book Print This Topic Email This Topic Pronunciations acromegaly amenorrhea amyloidosis angiography ... thalamus Hypopituitarism is an underactive pituitary gland that results in deficiency of one or more pituitary hormones. Hypopituitarism, an uncommon disorder, can be caused by a number of factors, including a pituitary tumor or an insufficient blood supply to the pituitary gland.

20. Array Comparative Genomic Hybridisation Analysis Of Boys With X analysis of boys with X linked hypopituitarism identifies a 3.9 Mb Keywords array CGH; duplication; hypopituitarism; Sox3; X linked http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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