61. Hypoparathyroidism hypoparathyroidism is a condition characterized by insufficient production of parathyroid hormones by the parathyroid glands, the small, oval glands located http://www.bchealthguide.org/kbase/nord/nord703.htm

var hwPrint=1;var hwDocHWID="nord703";var hwDocTitle="Hypoparathyroidism";var hwRank="1";var hwSectionHWID="nord703-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Hypoparathyroidism Important It is possible that the main title of the report Hypoparathyroidism is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Parathyroid, Underactivity of Tetany Disorder Subdivisions None General Discussion Resources Thyroid Foundation of America, Inc. 410 Stuart Street Boston, MA 02116 USA Tel: 6175341500 Fax: 6175341515 Tel: 8008328321 Email: info@allthyroid.org Internet: http://www.allthyroid.org Hypoparathyroidism Association, Inc. 2835 Salmon Street Idaho Falls, ID 83406 Tel: (208)524-3857 Fax: (208)524-2619 Email: hpth@hypoparathyroidism.org, hpth@cableone.net Internet: http://www.hypoparathyroidism.og NIH/National Digestive Diseases Information Clearinghouse 2 Information Way Bethesda, MD 20892-3570

62. Hypoparathyroidism - OhioHealth hypoparathyroidism is a deficiency of parathyroid hormone (PTH), which results in low blood calcium levels (hypocalcemia) and elevated blood levels of http://www.ohiohealth.com/healthreference/reference/CD45CB53-6947-49EF-B09D7ED8B

63. Indiana Hypoparathyroidism Regional Meeting On 7/17 The second annual Indiana regional meeting on hyperparathyroidism will be held on July 17th, 2004 in Columbus, Indiana. More information can be found online http://thyroid.about.com/b/a/098159.htm

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a74' About Thyroid Disease Thyroid Disease Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Thyroid Disease newsletter! See Online Courses Search Thyroid Disease Indiana Hypoparathyroidism Regional Meeting on 7/17 Thyroid Disease Blog Main From Mary Shomon Your Guide to Thyroid Disease FREE Newsletter. Sign Up Now! July 11, 2004 Indiana Hypoparathyroidism Regional Meeting on 7/17 The second annual Indiana regional meeting on hyperparathyroidism will be held on July 17th, 2004 in Columbus, Indiana. More information can be found online The second annual Indiana regional meeting will be held on July 17th, 2004. You are all invited to come and bring your family and friends to share in Hypoparathyroidism facts and to get to know each other. I am looking forward to hosting this second event. There will be food, and drink, and socializing. It will be very comfortable and relaxed. There will be air conditioning. That is a really hot time here in Indiana. So wear your t-shirts and shorts, flip flops and sandals. The event: Indiana regional meeting The time: 2:00 (afternoon) The Place: Two Worlds Club House, 2851 Two Worlds Drive, Columbus, IN 47201.

64. Hypoparathyroidism -- A Rare Disorder And The People It Hurts By Phyllis Jean Gr hypoparathyroidism A Rare Disorder and the People it Hurts. http://www.authorsden.com/visit/viewarticle.asp?AuthorID=8294&id=14048

65. Hypoparathyroidism Article Posted With Phyllis Jean Green (news) hypoparathyroidism A Rare Disorder and the People it Hurts Have you ever known anyone with hypoparathyroidism? Or a related disorder? http://www.authorsden.com/visit/viewnews.asp?AuthorID=8294&id=8470

66. Hypoparathyroidism - New Leaf Community Markets There are four parathyroid glands, located near each of the two lobes of the thyroid gland. The parathyroids produce parathyroid hormones that regulate http://www.newleaf.com/common/adam/DisplayMonograph.asp?storeID=J3QSSEQX5CS92J20

67. NEJM -- Hypoparathyroidism And Autoimmune Polyendocrine Syndromes Correspondence from The New England Journal of Medicine hypoparathyroidism and Autoimmune Polyendocrine Syndromes. http://content.nejm.org/cgi/content/short/351/10/1032

HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Please sign in for full text and personal services Previous Volume 351:1032-1033 September 2, 2004 Number 10 Next Hypoparathyroidism and Autoimmune Polyendocrine Syndromes Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings. Full Text PDF PDA Full Text Add to Personal Archive ... PubMed Citation To the Editor: In their review of autoimmune polyendocrine syndromes, Eisenbarth and Gottlieb (May 13 issue) do not, in our view, sufficiently discuss autoimmune hypoparathyroidism and recent advances in its understanding. Autoimmune hypoparathyroidism is present in 80 to 85 percent of patients with autoimmune polyendocrine syndrome type I and up to 5 percent of patients with autoimmune polyendocrine syndrome type II. The autoantigens were unknown until the extracellular domain of the calcium-sensing receptor was identified as a potential target. The calcium-sensing receptor which parathyroid cells, thyroidal C cells, and various kidney Full Text of this Article HOME SEARCH CURRENT ISSUE ... HELP Comments and questions? Please

68. NEJM -- Familial Hypocalcemia -- Not Hypoparathyroidism Editorial from The New England Journal of Medicine Familial Hypocalcemia Not hypoparathyroidism. http://content.nejm.org/cgi/content/short/335/15/1144

HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Please sign in for full text and personal services Previous Volume 335:1144-1145 October 10, 1996 Number 15 Next Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings. Full Text Add to Personal Archive Add to Citation Manager E-mail When Cited ... PubMed Citation Familial benign hypercalcemia, also known as familial hypocalciuric hypercalcemia, was first identified clinically when patients thought to have primary hyperparathyroidism whose condition did not improve after neck surgery were found to have relatives with hypercalcemia, thus suggesting a dominantly inherited condition. Unlike the index patient, the other affected family members were almost invariably asymptomatic. Although there were minor differences in serum and urinary biochemical values, such as lower urinary calcium excretion, in these patients as compared with patients with primary hyperparathyroidism, the two conditions have many similarities. The main danger of familial benign hypercalcemia is an unnecessary parathyroidectomy.

69. Endotext.com - Diseases Of Bone And Calcium Metabolism, Hypoparathyroidism And P A patient with neonatal hypoparathyroidism was found to be homozygous for a partial hypoparathyroidism can occur as part of a 22q11 microdeletion, http://www.endotext.org/parathyroid/parathyroid9/parathyroid9.htm

HYPOPARATHYROIDISM AND PSEUDOHYPOPARATHYROIDISM Chapter 9 - David E.C. Cole and Geoffrey N. Hendy June 17, 2005 Contents Contributors Search PRIMARY HYPOPARATHYROIDISM Primary hypoparathyroidism is caused by a group of heterogeneous conditions in which hypocalcemia and hyperphosphatemia occur as a result of deficient parathyroid hormone (PTH) secretion. This most commonly results from surgical excision of, or damage to, the parathyroid glands. However, autoimmune disease is also a significant factor in acquired cases, and genetic forms of hypoparathyroidism due to decreased PTH secretion are not uncommon (Table 1). Table 1. Forms of hypoparathyroidism having a genetic basis Isolated Autosomal dominant PTH gene mutation CASR activating mutation Autosomal recessive PTH gene mutation GCMB mutation X-linked Congenital multi-system syndromes Barakat/HDR Kenny-Caffey and Sanjad-Sakati Metabolic disease Mitochondrial neuromyopathies Long-chain hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency Heavy-metal storage disorders Autoimmune disease Autoimmune polyendocrine syndrome type I (APS-1 or APECED) Parathyroid resistance syndromes Pseudohypoparathyroidism Blomstrand chondrodysplasia and related PTH receptor defects Hypomagnesemia and other metabolic disorders The signs and symptoms of hypoparathyroidism include evidence of latent or overt neuromuscular hyperexcitability due to hypocalcemia (Table 2). The effect may be aggravated by hyperkalemia or hypomagnesemia, but there is wide variation in the severity of the symptoms. Patients may complain of circumoral numbness, paresthesias of the distal extremities or muscle cramping which can progress to carpopedal spasm or tetany. Laryngospasm or bronchospasm and seizures may also occur. Other less specific manifestations include fatigue, irritability, and personality disturbance.

70. HighWire -- Browse Journals - Hypoparathyroidism Browse Journals publishing on hypoparathyroidism, (return to Topic List page) Journals focusing on hypoparathyroidism (in order by highest focus) http://highwire.stanford.edu/lists/topic_dir/608683/618131/620271/620311/620312/

ANNOUNCEMENT: CHECK OUT THE PREVIEW RELEASE OF OUR NEW WEB SITE! My Favorite Journals ( HW-hosted journals HW-hosted Medline Author: Keyword(s): Year: Vol: Page: Home Adv. Search For Institutions For Publishers ... Sign in or register for access to all HighWire Press customization features Browse Journals publishing on Hypoparathyroidism: (return to Topic List page) Hypoparathyroidism Tetany Sort by: Alphabet Frequency of articles in Hypoparathyroidism Focus of journal on Hypoparathyroidism What's this? Journals focusing on Hypoparathyroidism (in order by highest focus) Pediatrics info free ISSUES Neurology ... Parathyroid Diseases Hypoparathyroidism Home Adv. Search For Institutions For Publishers ... partners/suppliers

71. Article - Hypoparathyroidism hypoparathyroidism is the state of decreased secretion or activity of parathyroid The most common cause of hypoparathyroidism is the loss of the active http://www.pens.org/articles/floyd-j.htm

Hypoparathyroidism Jackie Floyd, RN, BS, ONC Parathyroid glands are small glands of the endocrine system, which are located behind the thyroid. The sole purpose of the parathyroid glands is to regulate the calcium level in our bodies within a very narrow range so that the nervous and muscular systems can function properly (Perheentupa, 1996). Hypoparathyroidism is the state of decreased secretion or activity of parathyroid hormone (PTH). This leads to decreased blood levels of calcium (hypocalcemia) and increased levels of blood phosphorus (hyperphosphatemia). Symptoms range from quite mild (tingling in the hands, fingers, and around the mouth) to more severe forms of muscle cramps leading all the way to tetany (severe muscle cramping of the entire body), and convulsions (this is very rare)(Muir, 1998). Parathyroid gland insufficiency is quite rare, but can occur in different ways. The most common cause of hypoparathyroidism is the loss of the active parathyroid tissue following thyroid or parathyroid surgery. More rare is a defect present at birth (congenital) where a person is born without parathyroid glands. Occasionally, the specific cause of hypoparathyroidism cannot be determined. There are three categories of hypoparathyroidism, (1) deficient parathyroid hormone secretion, (2) inability to make an active form of PTH, and (3) inability of the kidneys and bone to respond to PTH (Muir, 1998). Deficient parathyroid hormone secretion can be from post surgical causes or idiopathic. Idiopathic is further divided into congenital or acquired. Congenital hypoparathyroidism is a condition in which the person is born without parathyroid tissue. They usually have no family history of the disease. The inherited forms tend to arise from abnormal genes that either: 1) encodes abnormal forms of PTH or its receptor, 2) prevent normal conduction of cell signals from the PTH receptor to the nucleus, or 3) prevent normal gland development before birth. The acquired form of the disease typically arises because the immune system had developed antibodies against the parathyroid tissues in an attempt to reject it as a foreign body. Responding to this the parathyroid stops making PTH (Muir, 1998).

72. Diseases: Johns Hopkins Autoimmune Disease Research Center Autoimmune hypoparathyroidism. Prepared by Daniela Cihakova MD, PhD Definition Autoimmune hypoparathyroidism is an autoimmune inflammatory disease of http://autoimmune.pathology.jhmi.edu/diseases.cfm?systemID=3&DiseaseID=17

73. Hill Health Topics A-Z - Hypoparathyroidism It is possible that the main title of the report hypoparathyroidism is not the hypoparathyroidism may result from absence of the parathyroid glands at http://www.healthwise.net/hillhealth/Content/StdDocument.aspx?DOCHWID=nord703&SE

74. Hypoparathyroidism - Washington DC hypoparathyroidism Washington Hospital Center is located in Washington DC. http://www.whcenter.org/13075.cfm

cddcodebase = "navtools/topmenu/";cddcodebase367050 = "navtools/topmenu/"; Article Manager Home Back to Health Library Print This Page ... Endocrine glands Hypoparathyroidism Definition: Hypoparthyroidism is a deficiency of parathyroid hormone that causes abnormal metabolism of calcium and phosphorus. Causes, incidence, and risk factors: Calcium and phosphorus are important body minerals. They form the mineral component of bones, and they exist as charged particles called ions in the blood and inside cells. Parathyroid hormone (PTH) regulates the amount of calcium and phosphorus in bone and blood. The four small parathyroid glands located in the neck, behind the thyroid, make PTH. Hypoparathyroidism is the clinical condition caused by a lack of PTH. Blood calcium levels fall, and phosphorus levels rise. Low blood calcium levels may cause symptoms such as tingling of the lips, fingers, and toes, and muscle cramps or spasms. The most common cause of hypoparathyroidism is injury to the parathyroid glands during head and neck surgery. Rarely, hypoparathyroidism is a side effect of radioactive iodine treatment for hyperthyroidism . PTH secretion may be impaired when blood levels of magnesium are low or when blood pH is too high, a condition called metabolic alkalosis.

75. BioSpace News: Hypoparathyroidism BioSpace News hypoparathyroidism. Lannett Company, Inc. (LCI) Announces The FDA Has Granted An AB Rating To Synthroid. PHILADELPHIA, Dec. http://www.biospace.com/news_rxtarget.cfm?RxTargetID=57204

76. Genetic Causes Of Hypoparathyroidism Hundreds of Bioscience books chapters in 60 categories Adhesion Molecules Immunoinformatics Agricultural Biotechnology, Plus Custom Bioscience books,and http://www.eurekah.com/abstract.php?chapid=2292&bookid=47&catid=23

77. Hypoparathyroidism (from Endocrine System, Human) --  Encyclopædia Britannica hypoparathyroidism (from endocrine system, human) If PTH secretion is greatly reduced or ceases entirely, mobilization of calcium from bone and other http://www.britannica.com/eb/article-45565

Home Browse Newsletters Store ... Subscribe Already a member? Log in Content Related to this Topic This Article's Table of Contents Expand all Collapse all Introduction Traditional endocrinology General features The nature of endocrine regulation Functions of the endocrine system Maintenance of homeostasis Growth and differentiation Adaptive responses to stress Parenting behaviour ... Anatomic considerations General aspects Integrative functions Anatomical considerations Hormone synthesis Regulatory mechanisms ... Biorhythms Endocrine dysfunction Endocrine hypofunction and receptor defects Endocrine hyperfunction The hypothalamus Anatomy Regulation of hormone secretion Hormones Thyrotropin-releasing hormone Gonadotropin-releasing hormone Corticotropin-releasing hormone Growth hormone-releasing hormone ... Gastrointestinal neuropeptides The anterior pituitary Anatomy Hormones Thyrotropin Gonadotropins Corticotropin Growth hormone ... Prolactin The posterior pituitary (neurohypophysis) Neurohypophyseal unit Oxytocin and vasopressin Diabetes insipidus and inappropriate secretion of vasopressin The thyroid gland ... Regulation of hormone secretion Diseases and disorders Hyperthyroidism Hypothyroidism Thyroid tumours The parathyroid glands ... Anatomy Hormones Parathyroid hormone Calcitonin Vitamin D and the calciferols Diseases and disorders Hyperparathyroidism changeTocNode('toc45557','img45557');

78. HPT - Hypoparathyroidism Idiopathic hypoparathyroidism associated with adult rheumatoid arthritis. Rheumatoid arthritis associated with hypoparathyroidism and Sj?gren s syndrome http://www.pdg.cnb.uam.es/UniPub/iHOP/gg/89162.html

Idiopathic hypoparathyroidism associated with adult rheumatoid arthritis Abstract-1997597 Parathyroid hormone effect on 1,25-dihydroxyvitamin D in hypoparathyroidism Abstract-3533904 Rheumatoid arthritis associated with hypoparathyroidism and Sj?gren's syndrome. Abstract-3374658 A donor splice site mutation in the parathyroid hormone gene is associated with autosomal recessive hypoparathyroidism Abstract-7539652 However, serum ICMA PTH levels were clearly suppressed or undetectable in the majority of patients with cancer hypercalcemia or postsurgical hypoparathyroidism Abstract-7371750 Thus, an unusual case of hypoparathyroidism after I-131 therapy with return of parathyroid function is documented by measurements of both immunoreactive and bioactive PTH Abstract-4315350 Hypoparathyroidism and deafness associated with pleioplasmic large scale rearrangements of the mitochondrial DNA : a clinical and molecular genetic study of four children with Kearns-Sayre syndrome Abstract-975224 These data and others from the literature suggest that chronic hypoparathyroidism enhances renal responses to PTH , consistent with the concept of hormonal regulation of tissue sensitivity to the hormone.

79. NDI Terminology - Hypoparathyroidism NDI Foundation. hypoparathyroidism. DEFINITION. The condition produced by greatly reduced function of the parathyroids possibly due to autoimmune disease http://www.ndif.org/Terms/hypoparathyroidism.html

hypoparathyroidism DEFINITION: The condition produced by greatly reduced function of the parathyroids possibly due to autoimmune disease or genetic factors , or by the removal of those bodies. The lack of parathyroid hormone leads to a fall in plasma calcium levelwhich may result in increased neuromuscular excitability and, ultimately, tetany followed by a rise in plasma phosphate level. Bone turnover is reduced; there may also be dermatologic ophthalmologic cataracts psychiatric , and dental symptoms , and associated primary failure of other endocrine glands , e.g., the adrenal cortex The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine , Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Dorland's Illustrated Medical Dictionary , 28th Edition, W. B. Saunders Company, Philadelphia, 1994; The Random House Dictionary of the English Language , Unabridged Edition, 1966;

80. Age And Ageing: Hypovitaminosis D And `functional Hypoparathyroidism'—the NoNoF Full text of the article, Hypovitaminosis D and `functional hypoparathyroidism —the NoNoF study Nottingham Neck of Femur - Statistical Data Included http://www.findarticles.com/p/articles/mi_m2459/is_6_30/ai_82263174

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