101. Virtual Naval Hospital: General Medical Officer Manual: Clinical Section hyperlipidemia. Department of the Navy Bureau of Medicine and Surgery hyperlipidemia is frequently encountered in routine screening and physical exams. http://www.vnh.org/GMO/ClinicalSection/50Hyperlipidemia.html

General Medical Officer (GMO) Manual: Clinical Section: Nutritional/Metabolic Disorders Hyperlipidemia Department of the Navy Bureau of Medicine and Surgery Peer Review Status: Internally Peer Reviewed (1) Introduction (2) Risk factors for coronary heart disease (3) Physical exam and laboratory studies (4) Treatment recommendations (5) Medications Medications ( see table 1 ) are added to, not substituted for treatment if the above target LDL levels are not met after a 6 month trial of diet and exercise, provided the patient is not high risk. Long-term follow-up is vital, as side effects may be significant (and asymptomatic) and patient motivation may wane. Contact the nearest internal medicine, endocrinology, or cardiology service for assistance in the specifics of evaluation and treatment of hyperlipidemia. Patients who require more than diet and one medication, who have secondary causes not readily evaluated or managed at the GMO level, or who are suspected of having CAD should be referred. Reference (a) National Cholesterol Education Program. (Adult Treatment Panel 11.) Summary of the Second Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults. JAMA 1993; 269:3015-3023.

102. Entrez PubMed It was concluded that hyperlipidemia is associated with PI use, becomes evidentwithin 3 months of treatment and seems to be substance specific. MeSH Terms http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

103. Penn State Faculty Research Expertise Database (FRED) , An excess of lipids in the blood. Related Terms.Dyslipidemia, Hyperlipemia. Dyslipidemias, Hyperlipemias. hyperlipidemias......hyperlipidemia. http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D006949

104. High Blood Cholesterol And Triglycerides Lipid disorders; hyperlipoproteinemia; hyperlipidemia. Causes, incidence, andrisk factors. Cholesterol can be bound to fat and protein at different http://www.healthcentral.com/ency/408/000403.html

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105. Hospital Practice: Detecting And Correcting Hyperlipidemia figure 1 Diabetes and hyperlipidemia are a potentially deadly combination. Any patient with hyperlipidemia will benefit from reduced lipid levels, http://www.hosppract.com/issues/1998/11/dmmhall.htm

Detecting and Correcting Hyperlipidemia RALPH R. HALL University of Missouri Case Commentary: STEPHEN A. BRUNTON University of California, Irvine The dangers of elevated serum cholesterol levelsand in particular, of increased concentrations of small, dense lipoproteinshave been fully delineated. Although effective therapies are available, too many physicians fail to look for hypercholesterolemia, or fail to treat it effectively. Adhering to therapeutic guidelines and encouraging patient compliance can be lifesaving. Dr. Hall is Professor of Medicine Emeritus, University of Missouri-Kansas City School of Medicine, and Medical Education Director, Colorado Physician Education Program. Dr. Brunton is Clinical Professor, Department of Family Medicine, University of California, Irvine, College of Medicine, and Executive Vice President, Education and Scientific Affairs, Clinical Communications Group, Greenwich, Ct. Case 1 Presentation A 56-year-old postmenopausal woman, whose employer had recently changed insurance plans, presented to her new primary care physician. Two years earlier she had been diagnosed with non-insulin-dependent diabetes mellitus (NIDDM) and had been treated with a maximum dose of a sulfonylurea. Her most recent glycosylated hemoglobin level was 8.6%. The patient did not have a history of heart disease, but treatment with simvastatin, 20 mg a day, had been initiated by her former physician because of hyperlipidemia. The pretreatment lipid levels had been total cholesterol, 242 mg/dL; high-density lipoprotein (HDL), 43 mg/dL; low-density lipoprotein (LDL), 199 mg/dL; and triglycerides, 430 mg/dL. After eight weeks of treatment, the total cholesterol level had fallen to 179 mg/dL, the LDL to 134 mg/dL, and the triglycerides to 280 mg/dL. The HDL level was 45 mg/dL.

106. Drugs For The Treatment And Prevention Of Hyperlipidemia An introductory article on various drugs for treatment of hyperlipidemia, withsummaries of scientific studies. http://www.anti-aging-guide.com/53hyperlipidemia.php

107. The Drug Monitor - Hyperlipidemia / Dyslipidemia - Nasr Anaizi, PhD Diverse topics in Clinical Pharmacy / Pharmacology aimed at the clinical professional.The topics include aminoglycosides and vancomycin monitoring, http://www.thedrugmonitor.com/hyperlipidemia.html

Please read the Antiinfectives General Rx Renal Rx Transplant Rx ... Clinical Tools Objectives Review the main risk factors for coronary heart disease (CHD) (per NCEP) Review of the basics of lipoprotein metabolism and the major lipid disorders. Review the guidelines for non-pharmacologic and pharmacologic management of hyperlipidemia. Review the current pharmacologic options for the treatment of hyperlipidemia. Review the pharmacology of atorvastatin. Mechanism of action Pharmacokinetics Efficacy Side effects Drug interactions Discuss the latest clinical trials comparing atorvastatin to other statins. Coronary heart disease (CHD) is one the leading causes of disability and death in the US. Although the etiology of CHD is multifactorial, there is an impress amount of evidence from experimental, epidemiological, and clinical studies indicating a strong association between coronary artery atherosclerosis and hypercholesterolemia below summarizes the main risk factors predisposing patients for the development of CHD: Table 1 Risk Factors For Coronary Heart Disease (CHD) Age Genetic factor: Family history of "premature" CHD

108. Hyperlipidemia: Side Effects And Patient Ratings For Prescription Drugs Consumer ratings reports for the hyperlipidemia drug class. Includes patientrankings on scale of 15, comments, side effects, sex, and age. http://www.askapatient.com/classreport.asp?class=HYPERLIPIDEMIA

109. Patient Resources Elevated Cholesterol Unregistered User. Click here if this is not your Personal Edition Contact Us Free EMail Updates Journals Register a colleague http://www.pslgroup.com/ELEVCHOL.HTM

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