61. Risk Factors For Progression To Incident Hyperinsulinemia: The Atherosclerosis R hyperinsulinemia is a marker of insulin resistance, a correlate of the metabolic diabetes, noninsulin-dependent; hyperinsulinemia; insulin resistance; http://aje.oxfordjournals.org/cgi/content/abstract/158/11/1058

JOURNAL HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Full Text Full Text (PDF) Alert me when this article is cited ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed ... Cited by other online articles Search for citing articles in: ISI Web of Science (5) Request Permissions PubMed PubMed Citation Articles by Carnethon, M. R. Articles by Chambless, L. E. Am J Epidemiol Johns Hopkins Bloomberg School of Public Health ORIGINAL CONTRIBUTIONS Mercedes R. Carnethon Stephen P. Fortmann Latha Palaniappan Bruce B. Duncan Maria I. Schmidt and Lloyd E. Chambless Stanford Center for Research in Disease Prevention, Stanford University School of Medicine, Palo Alto, CA. Current affiliation: Department of Preventive Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL. Department of Social Medicine, School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

62. JAX®Mice Database - Diabetes And Obesity Research: Hyperinsulinemia JAX®MICE Database Diabetes and Obesity Research hyperinsulinemia List. http://jaxmice.jax.org/jaxmicedb/html/model_60.shtml

Strain Information Services Information JAX Mice Literature Order Mice ... E-Mail Alerts Search Criteria: Area is "Diabetes and Obesity Research: Hyperinsulinemia" Strains Newly Available for all Diabetes and Obesity Research models. Strains from the Research Colonies of Jackson Laboratory Scientists New Strains Under Development Stock Number Strain Name (link to Data Sheet) Strain Type Standard Supply 129P3/J- Lepr db-3J /J Repository-Cryopreserved. Please refer to the Supply Notes for further information. ALS/LtJ Inbred Repository-Live. No age specifications accepted. Colony sized to produce minimal quantities (typically up to 6 mice) upon order receipt; one order per strain. Expected delivery: 1-3 months. Larger quantities or custom orders arranged upon request. /J Repository-Cryopreserved. Please refer to the Supply Notes for further information. B6.Cg- A y /J Level 3. Colony sized for average order of 5-15 mice. Larger quantities or custom orders arranged upon request. Age range recommended. B6.Cg- Tub tub /J Repository-Live. No age specifications accepted.

63. Hyperinsulinemia Syndrome X (hyperinsulinemia). By Eileen M. Wright, MD. All hormones including thyroid, testosterone, insulin, growth hormone, melatonin, cortisol, http://www.lafn.org/~av832/hyperins.html

64. Adiposity And Hyperinsulinemia In Indians Are Present At Birth (NDEI.ORG) Journal of Clinical Endocrinology Metabolism Adiposity and hyperinsulinemia in Indians Are Present at BirthC. S. Yajnik, HG Lubree, SS Rege, SS Naik, http://www.ndei.org/v2/website/litalerts/article.cfm?article_id=487&1=600613

65. Childhood Obesity, Hyperinsulinemia Are Risk Factors For Syndrome Childhood Obesity, hyperinsulinemia Are Risk Factors for Syndrome X. Source Srinivasan SR, Myers L, Berenson GS . Predictability of childhood adiposity and http://aapgrandrounds.aappublications.org/cgi/content/full/7/6/67a

66. Arch Fam Med -- Hyperinsulinemia In Hypertension: Associations With Race, Abdomi These data indicate that 2 components of hyperinsulinemia Because the components of hyperinsulinemia syndrome are inextricably linked to insulin http://archfami.ama-assn.org/cgi/content/full/7/1/53

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 7 No. 1, January 1998 Featured Link E-mail Alerts Original Contribution Article Options Abstract PDF Send to a Friend Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Spangler JG Konen JC ISI Web of Science (4) Contact me when this article is cited Topic Collections Obesity Hypertension Nutritional and Metabolic Disorders Lipids and Lipid Disorders ... Topic Collection Alerts Hyperinsulinemia in Hypertension Associations With Race, Abdominal Obesity, and Hyperlipidemia John G. Spangler, MD, MPH Ronny A. Bell, PhD John H. Summerson, MS Joseph C. Konen, MD, MSPH Arch Fam Med. ABSTRACT To determine the relative contributions of race, sex, abdominal obesity, and hyperlipidemia to the development of hyperinsulinemia among patients with hypertension.

67. Arch Fam Med -- Abstract: Hyperinsulinemia In Hypertension: Associations With Ra of hyperinsulinemia (adjusted odds ratio, 2.69; 95% confidence interval, 1.046.89; and adjusted odds ratio, 2.62; 95% confidence interval, 0.37-8.6, http://archfami.ama-assn.org/cgi/content/abstract/7/1/53

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 7 No. 1, January 1998 Featured Link E-mail Alerts Original Contribution Article Options Full text PDF Send to a Friend Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Spangler JG Konen JC ISI Web of Science (4) Contact me when this article is cited Topic Collections Obesity Hypertension Nutritional and Metabolic Disorders Lipids and Lipid Disorders ... Topic Collection Alerts Hyperinsulinemia in Hypertension Associations With Race, Abdominal Obesity, and Hyperlipidemia John G. Spangler, MD, MPH Ronny A. Bell, PhD John H. Summerson, MS Joseph C. Konen, MD, MSPH Arch Fam Med. To determine the relative contributions of race, sex, abdominal obesity, and hyperlipidemia to the development of hyperinsulinemia among patients with hypertension.

68. DOMINICI F P Et Al.: Role Of Hyperinsulinemia In GH-transgenic Mice (Journal Of Role of hyperinsulinemia on hepatic insulin receptor concentration and autophosphorylation in the presence of high growth hormone levels in transgenic mice http://journals.endocrinology.org/joe/159/joe1590015.htm

Role of hyperinsulinemia on hepatic insulin receptor concentration and autophosphorylation in the presence of high growth hormone levels in transgenic mice overexpressing GH gene F P Dominici , A Balbis , A Bartke and D Turyn Department of Physiology, School of Medicine, Southern Illinois University, Carbondale IL, 62901-6512, USA (Requests for offprints should be addressed to A Bartke) Abstract P P P P P Download the FULL TEXT of this article in Acrobat PDF format. If you have not previously downloaded PDF files we suggest you access our Advice page for further information. Journal of Endocrinology Return to the Contents List - Vol. 159 Part 1

69. Effects Of Acute Hyperinsulinemia On Plasma Atrial And Brain Natriuretic Peptide patients with hypertension associated with insulin resistance and hyperinsulinemia. To clarify the interrelationship between hyperinsulinemia and plasma http://www.eje-online.org/cgi/content/abstract/132/6/693

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager PubMed PubMed Citation Articles by Tanabe, A Articles by Demura, H European Journal of Endocrinology, Vol 132, Issue 6, 693-698 Articles Effects of acute hyperinsulinemia on plasma atrial and brain natriuretic peptide concentrations A Tanabe, M Naruse, T Wasada, K Naruse, T Yoshimoto, Y Omori, and H Demura Department of Medicine, Institute of Clinical Endocrinology, Tokyo, Japan. HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS

70. Kidney International Abstracts Title, Mechanisms of hyperinsulinemia in normoglycemic kidney transplant Postchallenge hyperinsulinemia is increased fivefold in KPA patients compared http://www.blackwellpublishing.com/kiabstracts/abstract.asp?id=18392

71. Hyperinsulinemia, Risk Of Cardiovascular Death And Acute Coronary And Cerebrovas BACKGROUND The role of hyperinsulinemia as a cardiovascular risk factor is We studied whether hyperinsulinemia is independently associated with http://www.uku.fi/neuro/ab0018.htm

U K U N E U R O S C I E N C E P U B L I C A T I O N S Lakka HM, Lakka TA, Tuomilehto J, Sivenius J, Salonen JT. Hyperinsulinemia and the risk of cardiovascular death and acute coronary and cerebrovascular events in men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Arch Intern Med 2000;160:1160-1168 Abstract BACKGROUND: The role of hyperinsulinemia as a cardiovascular risk factor is controversial. We studied whether hyperinsulinemia is independently associated with increased cardiovascular morbidity and mortality. METHODS: Fasting serum insulin level and other cardiovascular risk factors were determined in 1521 men in eastern Finland aged 42 to 60 years with neither cardiovascular disease nor diabetes at baseline. Forty-five cardiovascular deaths, 110 acute coronary events, 48 strokes, and 163 any cardiovascular events occurred during an average follow-up of 9.5 years. A total of 163 cardiovascular events (45 cardiovascular deaths, 110 acute coronary events, and 48 strokes) occurred during an average follow-up of 9.5 years. RESULTS: In Cox regression analysis adjusting for age and examination years, fasting serum insulin level as a continuous variable was directly associated with the risk of cardiovascular death (P = .006), acute coronary events (P = .04), and stroke (P = .02). Men with insulin levels of 52 to 66 pmol/L, 67 to 89 pmol/L, and 90 pmol/L or more (3 highest quartiles) had 1.4-fold (95% confidence interval, 0.5-3.7), 1.4-fold (95% confidence interval, 0.5-3.7), and 2.5-fold (95% confidence interval, 1.0-5.9; P = .05) cardiovascular mortality, respectively, compared with men with insulin levels of less than 52 pmol/L (lowest quartile) (P = .04 for linear trend). Adjustment for serum lipid levels, blood pressure, and obesity reduced the excess cardiovascular mortality in the highest insulin quartile by 7%, 33%, and 67%, respectively. There were no statistically significant differences in the incidence of acute coronary events and stroke between the insulin quartiles.

72. Weight Loss Is Effective Treatment For Hyperinsulinemia And Blood Pressure Weight Loss Treatment for hyperinsulinemia. Weight Loss is Effective Treatment for hyperinsulinemia and Blood Pressure http://www.weight-loss-i.com/weight-reduction/weight-loss-hyperinsulinemia.htm

weight loss information com Weight Loss is Effective Treatment for Hyperinsulinemia and Blood Pressure Weight Reduction Reduces Symptoms of Insulin Resistance and Metabolic Syndrome X Diet and Weight Loss Advice How to Reduce Weight Weight Loss - Treatment for Hyperinsulinemia Weight Reduction for Diabetics Weight Loss Advice for Diabetics Dieting and Blood Sugar Diet and Blood Sugar ... Does Weight Gain Increase the Risk of Diabetes Weight Loss Study Method Researchers from Duke Medical Center conducted a weight loss study to determine if a six-month intervention could have an effect on coronary heart disease risk factors associated with syndrome X. The study included 53 men and women who were part of a larger clinical trial. The participants suffered from insulin resistance, abnormal blood fats and high blood pressure. They were randomly assigned to the exercise only group, exercise and structured weight-loss program group, or the group that was on the waiting list for treatment. Weight Loss Study Results Researchers found the response to glucose in the body was significantly reduced in both the exercise only and exercise/weight-loss groups. They say participants who lost the most amount of weight showed the most improvements in abnormal insulin responses. Researchers also report the diastolic blood pressure level was significantly reduced in the exercise/weight-loss group, but not in the exercise only group. The lipid or fat profile was not significantly improved in either intervention group.

73. Hyperinsulinemia And Carotid Atherosclerosis hyperinsulinemia and carotid atherosclerosis. Data on parameters of fasting insulin and insulin response in the OGTT and carotid artery ultrasonography were http://herkules.oulu.fi/isbn9514264657/html/chapter5_4.html

Risk factors and carotid atherosclerosis in hypertensive and control subjects Prev Chapter 5. Results Next 5.4. Hyperinsulinemia and carotid atherosclerosis Data on parameters of fasting insulin and insulin response in the OGTT and carotid artery ultrasonography were available for 518 control and 513 hypertensive subjcts. Various parameters and calculated variables of fasting insulin and insulin response in the OGTT are shown in Table 2. The maximal IMT values and the mean and far-wall IMT and CPIMT values were presented above in 5.3. et al. 1985) and the area under curve (trapezoidal method), were statistically tested with IMT. The most powerful and most consistent predictor of IMT among the different insulin parameters in stepwise regression analyses was the 2-hour post-load insulin, which was used in the following analyses alone without any other insulin parameters in order to prevent multicollinearity. In the control groups 2-hour insulin had a weak non-significant positive correlation with IMT, but in the hypertensive groups it had a weak non-significant negative correlation with IMT. To determine whether an independent association between IMT and the different insulinemic measures existed, multiple forward and backward stepwise regression analyses (Table 9) were performed with different IMT parameters as the dependent variables and age, pack-years of smoking, LDL cholesterol, systolic BP and 2-hour insulin (data on serum 1-hour and 2-hour insulin concentrations, ISI, IRI and insulinemic area under curve not shown) as the independent variables. The independent variables were selected on the basis of predictive power and consistency in the different groups. Age was the most powerful independent predictor of IMT in all analyses and most consistently in the study groups (R

74. Acute Hyperinsulinemia, Androgen Homeostasis And Insulin Sensitivity In Healthy The acute effects of hyperinsulinemia on androgen homeostasis and a possible During hyperinsulinemia serum sex hormonebinding globulin (SHBG) http://joe.endocrinology-journals.org/cgi/content/abstract/146/1/63

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75. HighWire -- Browse Journals - Hyperinsulinemia Browse Journals publishing on hyperinsulinemia, (return to Topic List page) Journals focusing on hyperinsulinemia (in order by highest focus) http://highwire.stanford.edu:4141/lists/topic_dir/608683/608684/617569/617570/61

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76. Hyperinsulinemia And Coronary Artery Disease Risk Factors In Patients With Non-i hyperinsulinemia and coronary artery disease risk factors in patients with noninsulin-dependent diabetes mellitus and nondiabetics. RP Mozersky, VK Bahl, http://www.jaoa.org/cgi/content/abstract/96/10/591

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77. Hyperinsulinemia: The Missing Link Among Oxidative Stress And Age-related Diseas In this hypothesis paper, it is postulated that hyperinsulinemia may have such The hypothesis that hyperinsulinemia accelerates aging also offers a http://www.arclab.org/medlineupdates/abstract_11118820.html

Aging Research Center Home Page All Previous Aging Related Articles On-line Medical Dictionary National Library of Medicine's PubMed directory of MEDLINE citations. Hyperinsulinemia: the missing link among oxidative stress and age-related diseases? - Facchini FS, Hua NW, Reaven GM, Stoohs RA Free Radic Biol Med 2000 Dec 15;29(12):1302-6. Mounting evidence supports Harman's hypothesis that aging is caused by free radicals and oxidative stress. Although it is known that oxidant species are produced during metabolic reactions, it is largely unknown which factor(s), of physiological or pathophysiological significance, modulate their production in vivo. In this hypothesis paper, it is postulated that hyperinsulinemia may have such function and therefore promote aging, independently of elevations of glycemia. Hyperinsulinemia is secondary to impaired insulin stimulated glucose metabolism at the level of skeletal muscle (insulin resistance) and is seen in about one third of glucose tolerant humans following dietary carbohydrate intake. If other insulin-stimulated (or inhibited) pathways retain normal

78. Effects Of Hyperinsulinemia On The Subsequent Hormonal Response To Hypoglycemia of euglycemic hyperinsulinemia followed by a 45min fall in plasma glucose. Differing periods of euglycemic hyperinsulinemia had distinct effects on http://ajpendo.physiology.org/cgi/content/abstract/264/5/E748

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: Am J Physiol Endocrinol Metab This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Davis, S. N. Articles by Cherrington, A. D. ARTICLES Effects of hyperinsulinemia on the subsequent hormonal response to hypoglycemia in conscious dogs S. N. Davis, R. Dobbins, C. Colburn, C. Tarumi, J. Jacobs, D. Neal and A. D. Cherrington Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232-0615. The aim of this study was to determine if differing periods of prior hyperinsulinemic nonhypoglycemia can modify the subsequent counterregulatory response to hypoglycemia. Experiments were carried out on 19 normal 18-h fasted conscious dogs. Insulin was infused intraportally at

79. The Relationship Between Hyperinsulinemia, Hypertension And Progressive Renal Di The Relationship between hyperinsulinemia, Hypertension and Progressive Renal Disease. Fadi A. ElAtat , Sameer N. Stas , Samy I. McFarlane and James R. http://www.jasn.org/cgi/content/abstract/15/11/2816

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: J Am Soc Nephrol 15: 2816-2827, 2004 American Society of Nephrology doi: 10.1097/01.ASN.0000133698.80390.37 This Article Full Text Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by El-Atat, F. A. Articles by Sowers, J. R. FRONTIERS IN NEPHROLOGY The Relationship between Hyperinsulinemia, Hypertension and Progressive Renal Disease Fadi A. El-Atat Sameer N. Stas Samy I. McFarlane and James R. Sowers Department of Internal Medicine, University of Missouri-Columbia and H. S. Truman VAMC, Columbia, Missouri; Divisions of Cardiovascular Medicine and Endocrinology, Diabetes and Hypertension, Department of Medicine, State University of New York-Downstate Medical Center, Brooklyn, New York; USA and VA Medical Center, Brooklyn, New York. The incidence of end-stage renal disease (ESRD) has risen dramatically in the past decade, mainly due to the increasing prevalence

80. Acute Hyperinsulinemia And Very-low-density And Low-density Lipoprotein Subfract Background The influence of hyperinsulinemia on concentrations of Acute hyperinsulinemia modified the LDL subfraction profile toward a greater http://www.ajcn.org/cgi/content/abstract/71/2/443

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