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         Hyperhomocysteinemia:     more detail
  1. Hyperhomocysteinemia: Webster's Timeline History, 1992 - 2007 by Icon Group International, 2009-02-20
  2. Hyperhomocysteinemia as a result of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism causes an increased risk of cerebrovascular disease: ... An article from: Original Internist by Robert A., Jr. Duca, 2010-09-01
  3. Hyperhomocysteinemia in end stage renal disease: is treatment necessary? (Continuing Education).: An article from: Nephrology Nursing Journal by Jennifer Snavely, 2002-04-01

81. Folate Dependence Of Hyperhomocysteinemia And Vascular Dysfunction In Cystathion
The first wellcharacterized genetic model of hyperhomocysteinemia in hyperhomocysteinemia was defined as the elevation of plasma total homocysteine.
http://ajpheart.physiology.org/cgi/content/full/279/3/H970
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Am J Physiol Heart Circ Physiol
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PubMed PubMed Citation Articles by Lentz, S. R. Articles by Faraci, F. M. Vol. 279, Issue 3, H970-H975, September 2000
Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine -synthase-deficient mice
Steven R. Lentz Rochelle A. Erger Sanjana Dayal Nobuyo Maeda Donald D. Heistad , and Frank M. Faraci Veterans Affairs Medical Center, Iowa City 52246; Departments of Internal Medicine and Pharmacology, University of Iowa College of Medicine, Iowa City, Iowa 52242; Department of Pathology, University of North Carolina, Chapel Hill, North Carolina 27599; and Oregon Regional Primate Research Center, Beaverton, Oregon 97006

82. Hyperhomocysteinemia In Liver Cirrhosis: Mechanisms And Role In Vascular And Hep
hyperhomocysteinemia may develop as a consequence of defects in In fact, hyperhomocysteinemia has been reported in chronic alcoholics and in patients
http://hyper.ahajournals.org/cgi/content/full/38/5/1217
This Article Abstract Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Request Permissions PubMed PubMed Citation Articles by Avila, M. A. Related Collections Peripheral vascular disease Hypertension.
Fourth International Seminar on Cardiovascular Biology
and Medicine: Part I
Hyperhomocysteinemia in Liver Cirrhosis
Mechanisms and Role in Vascular and Hepatic Fibrosis
Carmen Berasain Roberto Arias
Abstract Abstract studies have identified elevated homocysteine levels in plasma as a risk factor for atherosclerotic vascular disease and thromboembolism. Hyperhomocysteinemia may develop as a consequence of defects in homocysteine-metabolizing genes; nutritional conditions leading to vitamin B , B , or folate deficiencies; or chronic alcohol consumption. Homocysteine is an intermediate in methionine metabolism, which takes place mainly in the liver. Impaired liver function leads to altered methionine and homocysteine metabolism; however

83. Hyperhomocysteinemia In Liver Cirrhosis: Mechanisms And Role In Vascular And Hep
hyperhomocysteinemia may develop as a consequence of defects in Determinants of hyperhomocysteinemia in patients with chronic liver disease and after
http://hyper.ahajournals.org/cgi/content/abstract/38/5/1217
This Article Full Text Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Request Permissions PubMed PubMed Citation Articles by Avila, M. A. Related Collections Peripheral vascular disease Hypertension.
Fourth International Seminar on Cardiovascular Biology
and Medicine: Part I
Hyperhomocysteinemia in Liver Cirrhosis
Mechanisms and Role in Vascular and Hepatic Fibrosis
Carmen Berasain Roberto Arias
Abstract Abstract studies have identified elevated homocysteine levels in plasma as a risk factor for atherosclerotic vascular disease and thromboembolism. Hyperhomocysteinemia may develop as a consequence of defects in homocysteine-metabolizing genes; nutritional conditions leading to vitamin B , B , or folate deficiencies; or chronic alcohol consumption. Homocysteine is an intermediate in methionine metabolism, which takes place mainly in the liver. Impaired liver function leads to altered methionine and homocysteine metabolism; however

84. Prevalence Of Moderate Hyperhomocysteinemia In Patients With Early-Onset Venous
The prevalence of hyperhomocysteinemia was almost twice as high when based on Inheritance of hyperhomocysteinemia and of the other defects was confirmed
http://www.annals.org/cgi/content/abstract/123/10/747
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Article Table of Contents Full Text of this article Figures/Tables List Services Send comment/rapid response letter Notify a friend about this article Alert me when this article is cited Add to Personal Archive ... ACP Search PubMed Articles in PubMed by Author: Fermo, I. D'Angelo, A. Related Articles in PubMed PubMed Citation ... PubMed
ARTICLE
Prevalence of Moderate Hyperhomocysteinemia in Patients with Early-Onset Venous and Arterial Occlusive Disease
Isabella Fermo, PhD Silvana Vigano' D'Angelo, MD Rita Paroni, PhD Giuseppina Mazzola, PhD ... Armando D'Angelo, MD
Objective: To evaluate the prevalence of moderate hyperhomocysteinemia and inherited thrombophilia disorders (congenital defects of the natural anticoagulant or fibrinolytic mechanisms) in patients with earlyonset venous or arterial thromboembolic disease. Design: Cross-sectional 2-year evaluation of consecutive unrelated patients with a history of venous or arterial occlusive disease occurring before the age of 45 years or at unusual sites, in the absence of local predisposing factors.

85. Ann Intern Med -- Sign In Page
hyperhomocysteinemia in Hypothyroidism. Daniel Weiss, MD Normalization of hyperhomocysteinemia with Lthyroxine in Hypothyroidism Wiam I. Hussein,
http://www.annals.org/cgi/content/full/132/8/677
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Hyperhomocysteinemia in Hypothyroidism
Weiss Ann Intern Med.
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86. Hyperhomocysteinemia, Oxidative Stress, And Cerebral Vascular Dysfunction -- Far
Do hyperhomocysteinemiainduced changes occur in the cerebral circulation hyperhomocysteinemia is a an emerging risk factor for carotid artery disease
http://www.strokeaha.org/cgi/content/full/35/2/345
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Advances in Stroke 2003
Hyperhomocysteinemia, Oxidative Stress, and Cerebral Vascular Dysfunction
Frank M. Faraci, PhD Steven R. Lentz, MD, PhD
From the Departments of Internal Medicine (F.M.F., S.R.L.) and Pharmacology (F.M.F.), Cardiovascular Center, University of Iowa Carver College of Medicine, Veteran Affairs Medical Center (S.R.L.), Iowa City, Iowa. Correspondence to Frank M. Faraci, PhD, Department of Internal Medicine, E315-GH, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242-1081. E-mail
Key Words: An elevated circulating concentration of the sulfur-containing amino acid homocysteine, hyperhomocysteinemia, produces complex changes within the blood vessel wall. In the peripheral circulation

87. Diet-Induced Hyperhomocysteinemia Exacerbates Neointima Formation In Rat Carotid
Moderate hyperhomocysteinemia (plasma homocysteine levels 3 to 4-fold higher than Mild hyperhomocysteinemia Induced by Feeding Rats Diets Rich in
http://circ.ahajournals.org/cgi/content/abstract/103/1/133
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Basic Science Reports
Diet-Induced Hyperhomocysteinemia Exacerbates Neointima Formation in Rat Carotid Arteries After Balloon Injury
Hiroyuki Morita, MD Hiroki Kurihara, MD Shigetaka Yoshida, MD Yuichiro Saito, MD Takayuki Shindo, MD Yoshio Oh-hashi, MD Yukiko Kurihara, MD Yoshio Yazaki, MD Ryozo Nagai, MD From the Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo (H.M., H.K., S.Y., T.S., Y.O., Y.K., R.N.) and the Hospital International Medical Center of Japan (Y.Y.), Tokyo, and the Second Department of Internal Medicine, Faculty of Medicine, Gumma University, Gumma (Y.S.), Japan. Dr H. Kurihara is now at the Division of Integrative Cell Biology, Department of Embryogenesis, Institute of Molecular Embryolosy and Genetics, Kumamoto University, Kumamoto, Japan. Correspondence to Hiroki Kurihara, MD, Division of Integrative Cell Biology, Department of Embryogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan. E-mail

88. Effects Of Methionine-Induced Hyperhomocysteinemia On Endothelium-Dependent Vaso
Moderate hyperhomocysteinemia Decreases EndothelialDependent Vasorelaxation in Pregnant Why Should Mild hyperhomocysteinemia Be Responsible for CAD?
http://circ.ahajournals.org/cgi/content/abstract/101/5/485
This Article Full Text Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Request Permissions PubMed PubMed Citation Articles by Chao, C.-L. Articles by Lee, Y.-T. Related Collections Endothelium/vascular type/nitric oxide
Cardiovascular imaging agents/Techniques

Risk Factors
Circulation.
Clinical Investigation and Reports
Effects of Methionine-Induced Hyperhomocysteinemia on Endothelium-Dependent Vasodilation and Oxidative Status in Healthy Adults
Chia-Lun Chao, MD Tsung-Li Kuo, MD, PhD Yuan-Teh Lee, MD, PhD From the Department of Internal Medicine (Cardiology), National Taiwan University Hospital (C.-L.C., Y.-T.L.), and the Department of Forensic Medicine (T.-L.K.), National Taiwan University College of Medicine. Correspondence to Yuan-Teh Lee, MD, Department of Internal Medicine (Cardiology), National Taiwan University Hospital, 7, Chung-Shan South Road, Taipei, 100, Taiwan, ROC. E-mail Background has been proposed to occur via oxidative stress mechanisms in humans. However, there is controversy regarding the effects

89. Nutrition.org -- Sign In Page
hyperhomocysteinemia (HH) constitutes a risk marker for thrombosis, Intermediate hyperhomocysteinemia was induced by a folic acid–deficient diet to
http://www.nutrition.org/cgi/content/full/135/8/1836
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Folate Deficiency-Induced Hyperhomocysteinemia Attenuates, and Folic Acid Supplementation...
Ebbesen and Ingerslev J. Nutr..
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90. Hyperhomocysteinemia And Macroangiopathy In Type 2 Diabetes -- Chan Et Al. 24 (6
hyperhomocysteinemia and Macroangiopathy in Type 2 Diabetes. N. Norman Chan, MRCP DCH , Tricia MM Tan, MRCP and Steven J. Hurel, PHD MRCP
http://care.diabetesjournals.org/cgi/content/full/24/6/1123
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by the American Diabetes Association, Inc.
Letters: Comments and Responses
Letter
Hyperhomocysteinemia and Macroangiopathy in Type 2 Diabetes
N. Norman Chan, MRCP DCH Tricia M.M. Tan, MRCP and Steven J. Hurel, PHD MRCP Department of Diabetes, Endocrinology, and Metabolism, University College London Hospitals, London, U.K. Elevated homocysteine is widely regarded as an independent risk factor for macrovascular disease, particularly in patients with type 2 diabetes ( ). The increased prevalence of macroangiopathy in type 2 diabetes is further demonstrated by Buysschaert et al. (

91. Effect Of Acute Hyperhomocysteinemia On Methylation Potential Of Erythrocytes An
However, the influence of acute hyperhomocysteinemia on MP is unknown. We induced acute hyperhomocysteinemia in 14 healthy volunteers by oral administration
http://ajprenal.physiology.org/cgi/content/abstract/00465.2004v1
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Am J Physiol Renal Physiol (April 26, 2005). doi:10.1152/ajprenal.00465.2004
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Accepted on April 19, 2005
Effect of acute hyperhomocysteinemia on methylation potential of erythrocytes and on DNA methylation of lymphocytes in healthy male volunteers
R Fux D Kloor M Hermes T Rock B Proksch A Grenz U Delabar R Bucheler S Igel K Morike C H Gleiter and H Osswald Division of Clinical Pharmacology in the Department of Pharmacology and Toxicology, University Hospital Tubingen, Tuebingen, Germany
Division of Pharmacology and Experimental Therapy in the Department of Pharmacology and Toxicology, University Hospital Tubingen, Tuebingen, Germany
To whom correspondence should be addressed. E-mail:

92. Occurrence Of Hyperhomocysteinemia 1 Year After Gastroplasty For Severe Obesity
Because hyperhomocysteinemia, an independent risk factor for cardiovascular disease, is influenced by nutritional status (and especially by folate intake),
http://jcem.endojournals.org/cgi/content/abstract/84/2/541

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Original Studies
Occurrence of Hyperhomocysteinemia 1 Year after Gastroplasty for Severe Obesity
Francoise Borson-Chazot Catherine Harthe Frederic Teboul Florence Labrousse Caroline Gaume Ludivine Guadagnino Bruno Claustrat Francois Berthezene and Philippe Moulin Severe obesity exposes one to an increased risk of cardiovascular mortality. Gastroplasty has been shown to induce substantial weight loss and to improve the atherogenic profile of severely obese subjects. However, vitamin deficiencies after gastroplasty have been reported. Because hyperhomocysteinemia, an independent risk factor for cardiovascular disease, is influenced by nutritional status (and especially

93. Occurrence Of Hyperhomocysteinemia 1 Year After Gastroplasty For Severe Obesity
Because hyperhomocysteinemia, an independent risk factor for hyperhomocysteinemia has progressively emerged as an independent risk factor for coronary,
http://jcem.endojournals.org/cgi/content/full/84/2/541

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Original Studies
Occurrence of Hyperhomocysteinemia 1 Year after Gastroplasty for Severe Obesity
Francoise Borson-Chazot Catherine Harthe Frederic Teboul Florence Labrousse Caroline Gaume Ludivine Guadagnino Bruno Claustrat Francois Berthezene and Philippe Moulin
Abstract Top
Abstract
Introduction
Subjects and Methods
Results
Discussion
References
Severe obesity exposes one to an increased risk of cardiovascular mortality. Gastroplasty has been shown to induce substantial weight loss and to improve the atherogenic profile of severely obese subjects. However, vitamin deficiencies after gastroplasty have been reported. Because hyperhomocysteinemia, an independent risk factor for cardiovascular

94. Hyperhomocysteinemia And Function Of The Endoplasmic Reticulum -- Ron 107 (10):
Study of hyperhomocysteinemia (HHcy) began with the desire to understand the complex hyperhomocysteinemia enhances vascular inflammation and accelerates
http://www.jci.org/cgi/content/full/107/10/1221
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Commentary
Hyperhomocysteinemia and function of the endoplasmic reticulum
David Ron Skirball Institute of Biomolecular Medicine, Departments of Medicine and Cell Biology and the Kaplan Cancer Center, New York University School of Medicine, New York, New York, USA Address correspondence to: David Ron, New York University Medical Center, SI 3-10, 540 First Avenue, New York, New York 10016, USA. Phone: (212) 263-7786; Fax: (212) 263-8951; E-mail: Study of hyperhomocysteinemia (HHcy) began with the desire to understand the complex phenotype associated with rare monogenic mutations that perturb homocysteine (Hcy) and methionine metabolism.

95. BioMed Central | Full Text | Diagnosis And Treatment Of Hyperhomocysteinemia
To obtain access to Current Atherosclerosis Reports through your institution use the options below. If you would like information about a personal
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