41. Hyperhomocysteinemia Presenting As Superior Mesenteric Artery Thrombosis Alexand Indian J Gastroenterol, The official publication of the Indian Society of Gastroenterology (ISG) http://www.indianjgastro.com/article.asp?issn=0254-8860;year=2005;volume=24;issu

42. Transplantation - Abstract: Volume 74(10) November 27, 2002 P 1359-1364 Hyperhom hyperhomocysteinemia and transplant coronary artery disease. hyperhomocysteinemia has been recognized as an important risk factor for atherosclerotic http://www.transplantjournal.com/pt/re/transplantation/abstract.00007890-2002112

LWWOnline LOGIN eALERTS REGISTER ... Archive Hyperhomocysteinemia and transplant... ARTICLE LINKS: Fulltext PDF (238 K) Hyperhomocysteinemia and transplant coronary artery disease. Transplantation. 74(10):1359-1364, November 27, 2002. Caldera, Angel 1; Dec, G. William 2 3 Abstract: Background. Transplant coronary artery disease (TCAD) is a major cause of morbidity and mortality among heart transplant recipients. A variety of immunologic and nonimmunologic mechanisms are involved in the pathogenesis of the disease. Hyperhomocysteinemia has been recognized as an important risk factor for atherosclerotic vascular disease. The purpose of this article is to evaluate the prevalence of hyperhomocysteinemia in heart transplant recipients but more specifically to assess the published literature regarding the association between hyperhomocysteinemia and TCAD. Methods. A MEDLINE search using the key words hyperhomocysteinemia, transplant coronary artery disease, and heart transplant was performed. Results. Hyperhomocysteinemia has been commonly found among heart transplant recipients (average prevalence 51% to 76%). Worsening renal function and impaired vitamin metabolism seem to be the major causes of hyperhomocysteinemia in this particular population. TCAD has been found to be more prevalent and severe among patients with higher serum homocysteine levels. Vitamin supplementation is safe and effective in reducing serum homocysteine among heart transplant recipients. Conclusion. A large, long-term, double-blind, placebo-controlled prospective trial aimed at assessing the clinical significance of homocysteine-lowering therapy on the natural history of TCAD seems warranted.

43. Transplantation - UserLogin hyperhomocysteinemia and transplant coronary artery disease hyperhomocysteinemia has been recognized as an important risk factor for atherosclerotic http://www.transplantjournal.com/pt/re/transplantation/fulltext.00007890-2002112

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44. Internet Scientific Publications, LLC. We present a patient with megaloblastic anemia and hyperhomocysteinemia due to vitamin Sodium valproate may lead to anemia and hyperhomocysteinemia by http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijpharm/vol3n1/valproa

45. CTF Structured Abstract: Hyperhomocysteinemia The prevalence of hyperhomocysteinemia in the general population is between 5 and 10%, based on a threshold set at the 90th or 95th percentile http://www.ctfphc.org/Abstracts_printable/Homocyst_abs.html

Please note: In 2003, the CTF updated its Grades of Recommendations to include an "I Recommendation" for situations where insufficient evidence exists to allow a recommendation to be made. (Formerly, these situations were captured under a "C Recommendation".) This change is not retroactive, and all "C Recommendations" made prior to 2003 have not been reevaluated in light of the new "I" recommendation grade. For a discussion of these recommendation grades, please link to the 2003 article in the Canadian Medical Association Journal here Preventive Health Care, 2000 Update: Screening and Management of Hyperhomocysteinemia for the Prevention of Coronary Artery Disease Events Prepared by Gillian L. Booth, MD, Departments of Medicine, Clinical Epidemiology and Health Care Research Program, University of Toronto, Elaine E. L. Wang, MD, Departments of Pediatrics, Clinical Epidemiology and Health Care Research Program, University of Toronto Objective To evaluate the quality of evidence pertaining to homocysteine and coronary artery disease (CAD) and make recommendations regarding screening and treatment of hyperhomocysteinemia.

46. CTF Selected References: Hyperhomocysteinemia Metaanalysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. hyperhomocysteinemia is associated with an increased risk of http://www.ctfphc.org/References/Homocyst_bib.html

Canadian Task Force on Preventive Health Care Selected References Preventive Health Care, 2000 Update: Screening and Management of Hyperhomocysteinemia for the Prevention of Coronary Artery Disease Events Prepared by Gillian L. Booth, MD, Departments of Medicine, Clinical Epidemiology and Health Care Research Program, University of Toronto, Elaine E. L. Wang, MD, Departments of Pediatrics, Clinical Epidemiology and Health Care Research Program, University of Toronto These recommendations were finalized by the Task Force in July 1999 Statistics Canada. Causes of death, 1995 (Catalogue 84-208-XPB). 1997. Ottawa, Minister of Industry. Brophy JM. The epidemiology of acute myocardial infarction and ischemic heart disease in Canada. data from 1976 to 1991. Can J Cardiol 1997;13:474-478. Skovby F. Inborn errors of metabolism causing homocysteinemia and related vascular involvement. Haemostasis 1989;19(suppl 1):4-9. Mudd SH, Skovby F, Levy HL, Pettigrew KD, Wilcken B, Pyeritz RE, Andria G, Boers GHJ, Bromberg IL, Cerone R, Fowler B, Gröbe H, Schmidt H, Schweitzer L. The natural history of homocystinuria due to cystathione-synthase deficiency. Am J Hum Genet 1985;37:1-31. Moghadasian MH, McManus BM, Frohlich JJ. Homocyst(e)ine and coronary artery disease. Clinical evidence and genetic and metabolic background. Arch Intern Med 1997;157:2299-2308.

47. Preventive Health Care, 2000 Update: Screening And Management Of Hyperhomocystei The prevalence of hyperhomocysteinemia in the general population is between 5% and 10% and may be as high as 30%–40% in the elderly population. http://www.guideline.gov/summary/summary.aspx?ss=15&doc_id=2702&nbr=1928

48. German Journal Of Psychiatry Bleich Hyperhomocysteinemia Manganese Induced Parki Moderate hyperhomocysteinemia and neuropsychiatric symptoms in This communication describes a moderate hyperhomocysteinemia in a patient with chronic http://www.gjpsy.uni-goettingen.de/gjp-article-bleich.htm

Home German Journal of Psychiatry ISSN 1433-1055 Moderate hyperhomocysteinemia and neuropsychiatric symptoms in manganese-induced parkinsonism Stefan Bleich, Detlef Degner, Borwin Bandelow, Antje Riegel , Juan M. Maler, Eckart Rüther, and Johannes Kornhuber Department of Psychiatry Department of Neuroradiology Georg-August University of Göttingen, Germany Corresponding author: Stefan Bleich, M.D, Department of Psychiatry, Georg-August University of Göttingen, von-Siebold-Str. 5, D-37075 Göttingen, Germany; e-mail stefan.bleich@t-online.de Abstract Manganese intoxication is a well-known cause of parkinsonism and dementia. Here we present the case of an 80-year-old patient with proven manganese poisoning. We observed no long-term progression of the manganese-induced parkinsonian syndrome. The blood manganese concentration is now reduced to below the normal range (4.8 m g/l), but the manganese concentration in scalp hair (2.79 m g/g) has kept on increasing. Strikingly, even though we found normal cobalamin and even elevated serum folate levels, we observed a moderate hyperhomocysteinemia in two independent samples. We did not find any common known risk factors for this moderate hyperhomocysteinemia The possible role of hyperhomocysteinemia in manganese-induced parkinsonism is discussed (German J Psychiatry 2000;3:14-20) Key words: manganese, homocysteine, parkinsonism

49. Journal Of The American College Of Nutrition -- Sign In Page Results hyperhomocysteinemia was found in 32 cases and in 4 controls. hyperhomocysteinemia is also suggested to be a risk factor of atherosclerosis http://www.jacn.org/cgi/content/full/23/5/386

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This item requires a subscription to Journal of the American College of Nutrition Online. Full Text Hyperhomocysteinemia, Enzyme Polymorphism and Thiobarbituric Acid Reactive System... Szamosi et al. J Am Coll Nutr. This Article Abstract Figures Only Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager PubMed PubMed Citation Articles by Szamosi, T. Articles by Szabo, T. To view this item, select one of the options below: Sign In User Name Sign in without cookies. Can't get past this page? Help with Cookies. Need to Activate? Password Forgot your user name or password? Purchase Short-Term Access Pay per Article - You may access this article (from the computer you are currently using) for 1 day for US$7.00 Pay for Admission - You may access all content in Journal of the American College of Nutrition Online (from the computer you are currently using) for 14 days for US$20.00.

50. Hyperhomocysteinemia, Enzyme Polymorphism And Thiobarbituric Acid Reactive Syste Results hyperhomocysteinemia was found in 32 cases and in 4 controls. Increased plasma THCy level was found in 10 children and adolescents from 12 cases http://www.jacn.org/cgi/content/abstract/23/5/386

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Figures Only Full Text Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager PubMed PubMed Citation Articles by Szamosi, T. Articles by Szabo, T. Journal of the American College of Nutrition, Vol. 23, No. 5, 386-390 (2004) Published by the American College of Nutrition Hyperhomocysteinemia, Enzyme Polymorphism and Thiobarbituric Acid Reactive System in Children with High Coronary Risk Family History Tamas Szamosi, MD, PhD, FACN Erzsebet Roth, MD, PhD Tamas Szamosi, Jr, MD Erika Tomsits, MD, PhD Attila Tordai, MD and Terez Szabo, MD, PhD 2nd Department of Pediatrics, Medical Faculty, Semmelweis University (T.S., E.T.), Budapest, HUNGARY Department of Research Surgery, Medical Faculty, University of Pecs (E.R.), Budapest, HUNGARY National Health Center (T.S.Jr., A.T.), Budapest, HUNGARY Address reprint requests to: Tamas Szamosi, M.D., Ph.D., 2

51. Hyperhomocysteinemia Induces Renal Hemodynamic Dysfunction: Is Nitric Oxide Invo This study investigated whether hyperhomocysteinemia induces renal oxidative hyperhomocysteinemia is an independent risk factor of arteriosclerosis, http://www.jasn.org/cgi/content/full/14/3/653

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Abstract Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Fischer, P. A. Articles by Masnatta, L. D. J Am Soc Nephrol 14:653-660, 2003 American Society of Nephrology Hyperhomocysteinemia Induces Renal Hemodynamic Dysfunction: Is Nitric Oxide Involved? Patricia A. Fischer Graciela N. Dominguez Luis A. Cuniberti and Lucas D. Masnatta *Section of Pharmacology, Department of Physiology, and Lipid and Atherosclerosis Research Laboratory, Department of Pathology, Favaloro University, Buenos Aires, Argentina. Abstract Top Abstract Introduction Materials and Methods Results Discussion References ABSTRACT. Hyperhomocysteinemia is associated with endothelial dysfunction, although the underlying mechanism is unknown. Previous

52. Effect Of High Dose Folic Acid Therapy On Hyperhomocysteinemia In Hemodialysis P Comparison of the number of patients who had hyperhomocysteinemia at baseline Two of these 12 presented with moderate hyperhomocysteinemia at this time http://www.jasn.org/cgi/content/full/11/6/1106

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Abstract Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by SUNDER-PLASSMANN, G. J Am Soc Nephrol 11:1106-1116, 2000 American Society of Nephrology REGULAR ARTICLES Effect of High Dose Folic Acid Therapy on Hyperhomocysteinemia in Hemodialysis Patients Results of the Vienna Multicenter Study GERE SUNDER-PLASSMANN HEIDI BUCHMAYER MENELAOS PAPAGIANNOPOULOS JADWIGA WOJCIK JOSEF KLETZMAYR BRIGITTE ENZENBERGER OSKAR JANATA WOLFGANG C. WINKELMAYER GERNOT PAUL MARTIN AUINGER URSULA BARNAS and 3. Medizinische Abteilung, Krankenhaus Lainz, Vienna, Austria 1. Medizinische Abteilung, Donauspital, Vienna, Austria 1. Medizinische Abteilung, Kaiser Franz Josef Spital, Vienna, Austria. Abstract Top Abstract Introduction Materials and Methods Results Discussion References Abstract . Homocysteine is associated with atherosclerosis and enhanced cardiovascular risk. In previous studies, treatment with folic

53. Hyperhomocysteinemia, Pregnancy Complications, And The Timing Of Investigation - RESULTS hyperhomocysteinemia was associated with an approximately 2fold to CONCLUSION hyperhomocysteinemia and vitamin deficiencies are largely http://www.greenjournal.org/cgi/content/abstract/104/2/336

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Full Text Full Text (PDF) Alert me when this article is cited ... Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager ... Cited by other online articles PubMed PubMed Citation Articles by Steegers-Theunissen, R. P. Articles by Steegers, E. A. Related Collections Basic Science Epidemiology/public health Maternal/fetal physiology Nutrition/metabolism ... Pathology ORIGINAL RESEARCH Hyperhomocysteinemia, Pregnancy Complications, and the Timing of Investigation Carola A. Van Iersel, MSc Petronella G. Peer, PhD Willianne L. Nelen, PhD and Eric A. Steegers, PhD From the Departments of *Obstetrics and Gynecology, and Epidemiology and Biostatistics, University Medical Center Nijmegen, Nijmegen; and Departments of Obstetrics and Gynecology, Erasmus University Medical Center, Rotterdam, the Netherlands OBJECTIVE: To assess associations between vitamin-dependent homocysteine metabolism and vascular-related pregnancy complications by considering interval between delivery and postpartum investigation and maternal age.

54. Homocysteine Causes of hyperhomocysteinemia. Vitamin Deficiency Folate Deficiency Vitamin B6 Deficiency; Vitamin B12 Deficiency. Chronic Disease http://www.fpnotebook.com/CV250.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Cardiovascular Medicine Prevention Coronary Artery Disease ... Alcohol Related Cardiac Effects Homocysteine Cardiac Risk Factor Cardiac Risk Management Hypertension Hypertension General Measures ... Low Fat Diet Homocysteine Hyperhomocysteinemia Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Practice Management Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Cardiovascular Medicine Index Arrhythmia Coronary Artery Disease Congestive Heart Failure EKG Endocrinology Examination Ophthalmology Geriatric Medicine Hypertension Infectious Disease Laboratory General Hyperlipidemia Pulmonology Myocardium Neurology Neonatology Obstetrics Pediatrics Pericardium Pharmacology Prevention Procedure Radiology Sports Medicine Surgery Symptom Evaluation Valvular Disease Vessel Page Prevention Index CAD Alcohol CAD Homocysteine CAD Risk Factors CAD Risk Management Htn Lipid Diet See Also Homocystinuria Hypercoagulable State Epidemiology Elevated in 15-30% of patients with premature CAD Pathophysiology Folate needed to convert homocysteine to methionine May reduce CAD risk by lowering homocysteine levels Dose response curve: lowest Folate, Highest risk

55. Arch Intern Med -- Abstract: Meta-analysis Of Hyperhomocysteinemia As A Risk Fac hyperhomocysteinemia, Low Folate and Vitamin B12 Concentrations, and Methylene Tetrahydrofolate Reductase Mutation in Cerebral Venous Thrombosis http://archinte.ama-assn.org/cgi/content/abstract/158/19/2101

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 158 No. 19, October 26, 1998 Featured Link E-mail Alerts Original Investigation Article Options Full text PDF Send to a Friend Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Ray JG Articles that cite this article ISI Web of Science (97) Contact me when this article is cited Topic Collections Evidence-Based Medicine Venous Thromboembolism Topic Collection Alerts Meta-analysis of Hyperhomocysteinemia as a Risk Factor for Venous Thromboembolic Disease Joel G. Ray, MD, FRCP Arch Intern Med. Elevated plasma homocysteine (Hcy) levels are implicated in the development of atherosclerotic and venous thromboembolic disease. A meta-analysis of the risk for venous thromboembolism (VTE) in the presence of hyperhomocysteinemia (hyper-Hcy) was performed.

56. Arch Intern Med -- Abstract: Hyperhomocysteinemia And Atherosclerotic Vascular D hyperhomocysteinemia has recently been identified as an important risk Screening for hyperhomocysteinemia should be considered for patients at high risk http://archinte.ama-assn.org/cgi/content/abstract/158/12/1301

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 158 No. 12, June 22, 1998 Featured Link E-mail Alerts Review Article Article Options Full text PDF Send to a Friend Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Stein JH McBride PE Articles that cite this article ISI Web of Science (68) ... Contact me when this article is cited Topic Collections Review Topic Collection Alerts Hyperhomocysteinemia and Atherosclerotic Vascular Disease Pathophysiology, Screening, and Treatment James H. Stein, MD Patrick E. McBride, MD, MPH Arch Intern Med. Hyperhomocysteinemia has recently been identified as an important risk factor for atherosclerotic vascular disease. This article reviews homocysteine metabolism, causes of hyperhomocysteinemia, the pathophysiological findings of this disorder, and epidemiological

57. Disclaimer - Electronic Collection The prevalence of hyperhomocysteinemia in the general population is between Definitive guidelines for the management of hyperhomocysteinemia await the http://collection.nlc-bnc.ca/100/201/300/cdn_medical_association/cmaj/vol-163/is

You are viewing a document archived by Library and Archives Canada. Please note, information may be out of date and some functionality lost. You will be redirected in 15 seconds or follow this link to continue to the document For more information see the Electronic Collection's Web site. Vous visualisez un document archivé par Bibliothèque et Archives Canada. Veuillez noter que l’information peut être périmée et que certaines fonctions peuvent être inactives. Vous serez redirigé dans 15 secondes ou suivez ce lien pour voir le document Pour plus de renseignements veuillez consulter le site Web de la Collection électronique Last Updated: 2005-04-12 Important Notices Avis importants

58. RESISTANCE ARTERY MECHANICS IN MICE WITH HYPERHOMOCYSTEINEMIA: EFFECTS OF ANGIOT hyperhomocysteinemia (HHcy) may be an independent risk factor for The purpose of this study was to evaluate whether hyperhomocysteinemia may induce http://www.ccs.ca/society/congress2002/abstracts/abs/a245.htm

Return to Table of Contents RESISTANCE ARTERY MECHANICS IN MICE WITH HYPERHOMOCYSTEINEMIA: EFFECTS OF ANGIOTENSIN II Mario Fritsch Neves, Agostino Virdis, Rima Rozen*, Ernesto L Schiffrin Clinical Research Institute of Montreal, University of Montreal and *Montreal Children’s Hospital Research Institute, McGill University, Montreal, Quebec, Canada Hyperhomocysteinemia (H-Hcy) may be an independent risk factor for atherosclerotic vascular disease. The purpose of this study was to evaluate whether hyperhomocysteinemia may induce direct vascular changes. Wild-type (+/+) and heterozygous (+/-) methylenetetrahydrofolate reductase (Mthfr) knockout mice, a model of mild H-Hcy, were divided in four groups for a 2-week treatment: wild-type with vehicle infusion (+/+ sham), wild-type with angiotensin (Ang) II infusion (400 ng/Kg/min s.c.), Mthfr +/- sham and Mthfr +/- with Ang II. Second-order branches of mesenteric arteries (lumen diameter < 300 mm) were mounted on a pressurized myograph and exposed to intraluminal pressures ranging from 3 to 140 mmHg. Media thickness and lumen diameter were measured at each pressure level to determine wall mechanical properties. In wild-type mice Ang II determined eutrophic remodeling, increasing media-to-lumen (M/L) ratio (7.5 ± 0.3 vs 5.7 ± 0.2 % ,p <0.01) but not media cross-section (8375 ± 703 vs 9527 ± 494, p>0.05). In Mthfr +/- mice Ang II induced hypertrophic remodeling with increased M/L ratio (7.2 ± 0.2 vs 6.3 ± 0.3 %, p

59. ROLE OF HYPERHOMOCYSTEINEMIA IN THE DEVELOPMENT OF ATHEROSCLEROSIS hyperhomocysteinemia is a strong and independent risk factor for cardiovascular disease. Our results indicate that hyperhomocysteinemia accelerates http://www.ccs.ca/society/congress2002/abstracts/abs/a153.htm

Return to Table of Contents ROLE OF HYPERHOMOCYSTEINEMIA IN THE DEVELOPMENT OF ATHEROSCLEROSIS* J Zhou, GH Werstuck, L Watson, GS Hossain, ABL de Koning, YY Shi, SK Sood, RC Austin Henderson Research Centre and Mcmaster University, Hamilton, Ontario *Supported in part by the Heart and Stroke Foundation of Ontario DNC NEXT

60. ASCO - Browse By Meeting - Hyperhomocysteinemia In Cancer Patients With Thrombos The American Society of Clinical Oncology (ASCO) is the world s leading professional organization representing physicians who treat people with cancer. http://www.asco.org/ac/1,1003,_12-002636-00_18-0026-00_19-004148,00.asp

HOME ABOUT ASCO PRESS CENTER STATE AFFILIATES ... Career Resources Pay Membership Dues, Membership Directory, Drug Database, Update Your Profile username password Remember Me Forgot your password? Create a guest account BECOME A MEMBER Journal of Clinical Oncology Journal of Oncology Practice The ASCO Foundation People Living With Cancer BECOME A SPONSOR The remember me feature is an automatic login process which creates a cookie on the hard drive of your computer containing your username and password, thereby avoiding the need to enter them upon subsequent visits to asco.org. DO NOT select this option if you share this computer with others since personal or member only information will be accessible by other users. For addition information please review our . Click OK to keep the Remember Me option, or click Cancel to remove it. When you are done, click the LOGIN button to continue with the login Process . Home Abstracts Browse by Meeting Meeting: 2004 ASCO Annual Meeting Printer Friendly Bookmark Category: Health Services Research SubCategory: Health Services Research Hyperhomocysteinemia in cancer patients with thrombosis is independent of methylene tetrahydrofolate reductase gene mutation.

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