81. Karger Publishers Objectives and Importance Hughes (antiphospholipid) syndrome is mainly seen It is, therefore, recommended that the possibility of hughes syndrome be http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ProduktNr=

82. Surgery Door - Support Groups The hughes syndrome Foundation. The Rayne Institute St Thomas Hospital The hughes syndrome Foundation aims to offer understanding and support to http://www.surgerydoor.co.uk/sg/detail.asp?Recno=26740738

83. Health/Conditions And Diseases/Immune Disorders/Auto-Immune/Antiphospholipid Syn Medical research information on APLS, APS, APLAS or hughes syndrome and related blood disorders. url www.apscore.org; The hughes syndrome Foundation http://www.thedoctorslounge.net/dir/Health/Conditions_and_Diseases/Immune_Disord

Advertisement Powered by Careerbuilder Search for: Home Humor Advertising Contact ... Links Specialties Cardiology Chest diseases Dermatology Endocrinology ... Urology Other Sections Membership Research Tools Medical Tutorials Medical Software ... Specialized Centers Headlines: The Medical Website Directory Popular Categories Popular Links Web Sites report abuse/spam url: report-abuse.dmoz.org/?cat=Health/Conditions_and_D... Antiphospholipid Antibody Syndrome Medical research information on APLS, APS, APLAS or Hughes Syndrome and related blood disorders. url: apls.freelinuxhost.com/index.html Antiphospholipid Antibody Syndrome Forum Delphi message board and chat room for anyone with an interest in the disorder. [Requires free registration.] url: forums.delphiforums.com/apssupport/start Antiphospholipid Antibody Syndrome on the Net Features background information, message board, chat room, and related links. url: www.mindspring.com/~waxman/ The Antiphospholipid Syndrome By Sara Marder, M.D. An explanation of this order and its association with pregnancy loss, who should be tested and its treatment. url: hygeia.org/poems4.htm

84. Ivanhoe's Medical Breakthroughs - Discussion Groups Reply to This Post Back to This Discussion Discussion Group List . hughes syndrome (aka Antiphospholipid Antibody Syndrome) Email a Friend http://www.ivanhoe.com/discussion/p_discussion.cfm?forumid=3&messageID=34235&act

85. Bienvenidos A Tienda Aula Médica, Librería Especializada En Medicina Translate this page hughes syndrome Autor MA Khamashta Editorial Springer Nº Edición 1st Idioma Inglés Año 2006 Nº Volúmenes 1 129.95 € Comprar *IVA no incluido http://www.libreriasaulamedica.com/ficha.asp?id=11871&fam=1&subcat=Reumatología

86. Republika Online - Http://www.republika.co.id Saya menderita hughes syndrome. Yang ingin saya tanyakan ialah 1. Apakah yang dimaksud hughes syndrome itu? Apa sebabnya dan bisa sembuh tidak? 2. http://www.republika.co.id/suplemen/cetak_detail.asp?mid=2&id=173114&kat_id=105&

87. Science Blog -- Cedars-Sinai Medical Center Physicians And Scientists Present Fi Dr. Graham will present the case of a child with Colehughes syndrome, a disorder characterized by an abnormally large head (macrocephaly) and mental http://www.scienceblog.com/community/older/1999/A/199900901.html

From: Cedars-Sinai Medical Center Cedars-Sinai Medical Center Physicians And Scientists Present Findings At Annual Meeting Of The Pediatric Academic Societies LOS ANGELES (May 2, 1999) Researchers at Cedars-Sinai Medical Center are presenting three scientific lectures and several poster-session exhibits at the Pediatric Academic Societies' 1999 Annual Meeting May 1 through 4 in San Francisco. The first lecture was presented at 9:45 a.m. Sunday, May 2, as part of a program on neuroprotective strategies for hypoxic-ischemic encephalopathy - the effort to reduce or prevent damage to brain cells when blood supply to the brain is reduced or blood to the brain contains insufficient oxygen. For some time, researchers have thought that the administration of magnesium may have a "protective effect" on brain cells, although the exact mechanism has not been understood. Neonatologist Richard C. Krueger, Jr., M.D., Ph.D., discussed the results of a study that advances this theory, suggesting that the administration of magnesium "could have a dramatic impact on neural development." The study was conducted by researchers at Cedars-Sinai and Chicago Children's Hospital. The researchers placed brain cells of embryonic chickens into a culture containing only a small amount of magnesium. After five days, they added another measured amount of magnesium, analyzing the cells 24 hours later for overall viability (the ability to live, grow and develop), apoptosis (disintegration), and proliferation (reproduction).

88. Renal Artery Stenosis In The Antiphospholipid (Hughes) Syndrome And Hypertension Medline; Godfrey T, Khamashta MA, Hughes GRV. Antiphospholipid syndrome and Medline; George J, Shoenfeld Y. The antiphospholipid hughes syndrome a http://ard.bmjjournals.com/cgi/content/full/62/10/999

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS Author Keyword(s) Vol Page [Advanced] This Article Abstract Full Text (PDF) Submit a response ... Citation Map Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Sangle, S R Articles by Hughes, G R V Related Collections Other Rheumatology Annals of the Rheumatic Diseases CONCISE REPORT Renal artery stenosis in the antiphospholipid (Hughes) syndrome and hypertension S R Sangle W Jan M Y Karim M A Khamashta I C Abbs and G R V Hughes Correspondence to: Dr S R Sangle; Accepted 17 February 2003 ABSTRACT Background: Hypertension is common in the antiphospholipid (Hughes) syndrome (APS) and its cause is poorly understood. Anecdotal evidence suggests that renal artery stenosis (RAS) may be a relevant and treatable cause of hypertension.

89. Monicas Lupus - Associated Autoimmune Conditions - Antiphospholipid Living with hughes syndrome (Overcoming Common Problems) Graham Hughes hughes syndrome, also known as Sticky Blood, as identified in the 1980s and it is http://www.monicaslupus.co.uk/antiph.htm

Antiphospholipid Syndrome T he syndrome was discovered by Dr Graham Hughes and named the Hughes Syndrome. Although this syndrome was first discovered in lupus patients it is now recognised that many, if not the majority, of patients with Hughes’ syndrome have no other features of lupus nor will they develop lupus in the future as Dr Hughes succinctly puts it in his paper "Some Lupus patients have Antiphospholipid Syndrome but not many!" In 1983 Dr Graham Hughes and his colleagues described a condition often known as “sticky blood”, in which there was a danger of thrombosis. Patients with the syndrome were at risk, both from vein thrombosis (including DVT’s ), and in some, more dangerous arterial thrombosis, including a risk of strokes and heart attacks. In women with the syndrome, the “sticky blood” is unable to get through the sensitive small blood vessels to the fetus, and there is a risk of miscarriage. Fortunately, the syndrome is usually detected by a simple blood test, and correct treatment is effective – usually very effective. The aim of the treatment is to thin the blood – the commonly used medicines being either low dose (‘junior’) aspirin, heparin or

90. The Antiphospholipid Syndrome (Hughes' Syndrome) The antiphospholipid syndrome (APS) is sometimes called sticky blood syndrome . This is because people with it have an increased tendency to form clots in http://www.netdoctor.co.uk/diseases/facts/antiphospholipid.htm

Search: All NetDoctor Diseases Medicines NetDoctor.co.uk Home News and features News News archive Newsletter Features Encyclopaedia Diseases Examinations Medicines Premium services SMS services StayQuit thediet Health centres ADHD Allergy and asthma Children's health Depression ... All health centres Discussion and support Discussion forums Support groups Services Ask the doctor Find a hospital Search Medline Test yourself Information About NetDoctor Commercial opportunities NetDoctor.com The antiphospholipid syndrome (Hughes' syndrome) Written by Dr MY Karim , lecturer in immunology, St Thomas' Hospital and Dr GRV Hughes , consultant physician and rheumatologist, St Thomas' Hospital What is the antiphospholipid syndrome (Hughes' syndrome)? The antiphospholipid syndrome (APS) is sometimes called 'sticky blood syndrome'. This is because people with it have an increased tendency to form clots in blood vessels (also known as thromboses). Any blood vessel can be affected including the veins, which are thin walled and take blood towards the heart, and the arteries, which have thick muscular walls, and take blood away from the heart. As a result of this clotting tendency these patients may develop repeated clots, eg in the veins of the leg (deep vein thrombosis), or in the arteries supplying the brain, causing a stroke. In pregnancy, the placenta can be affected by small clots, and there is an increased risk of miscarriage, particularly in mid-pregnancy.

91. Welcome To The Hughes Family Homepage This family tells about their homeschool and the challenges of raising a child with Down's syndrome. http://www.geocities.com/Heartland/Plains/5114/

We would like to take this opportunity to express our deepest sympathy to those who have been affected by the tragedy on September 11, 2001.  We ask you to pray for our president and those who will be making decisions in the days to come regarding what course of action this country will take.  We are so thankful for the firemen and the police who have been working around the clock in the clean-up effort. Please remember to thank those firemen and policemen in your local community who serve you and help to keep you safe. Let us draw together and stand in unity during this very difficult time. Welcome to the Hughes Family Homepage Please come in and visit... and won't you please sign our guestbook to let us know that you were here? Thanks for visiting! You are visitor # since 12-07-97 Thank you, Irene, for such beautiful graphics! All graphics on this page are by Graphics by Irene except the In Memory graphic which is from Mary's Little Lamb A big thanks to Mary for making it available!

92. Hughes' Syndrome hughes syndrome The antiphospholipid syndrome. The primary antiphospholipid syndrome (hughes syndrome). We published similar features seen in http://www.infotech.demon.co.uk/APS2.htm

Hughes' Syndrome: The antiphospholipid syndrome. A historical view Dr. Graham R.V. Hughes, MD FRCP The Rayne Institute St. Thomas' Hospital, London, UK. (First printed in Lupus: An International Journal, Volume 7 Supplement 2: 8th International Symposium on Antiphospholipid Antibodies. Sapporo, Japan, 6-9 October 1998.) (Full references have been omitted and the reader should refer to the above journal or to Stockton Press Introduction In 1983 we described a complex clinical syndrome, characterised by thrombosis, recurrent abortion, neurological disease and anti-phospholipid antibodies. In the 1983 "Prosser-White Oration" to the British Society of Dermatology, the following passages still seem clinically appropriate 15 years later: "Although many of these patients fall under the general heading of lupus, or lupus-like disease, I believe that the group is sufficiently homogenous and in some ways (such as the frequently negative ANA serology) sufficiently different from typical systemic lupus erythematosus (SLE) to warrant separate consideration. the manifestations of this syndrome are thrombosis (often multiple) and frequently, spontaneous abortions (often multiple), neurological disease, thrombocytopenia and livedo reticularis. The livedo reticularis is often florid on the knees. This may or may not be associated with mild to moderate Raynaud's phenomenon. These patients' blood pressures often fluctuate, apparently correlating with the severity of the livedo, suggesting a possible reno-vascular aetiology. However, this group of patients rarely has primary renal disease.

93. The Antiphospholipid Syndrome (Hughes' Syndrome) What is the antiphospholipid syndrome (hughes syndrome)? The antiphospholipid syndrome (APS) is sometimes called sticky blood syndrome . http://www.tiscali.co.uk/lifestyle/healthfitness/health_advice/netdoctor/archive

// Show bread crumbs navigation path. breadcrumbs('five'); //> From: www.tiscali.co.uk/lifestyle/ Calculators Calorie Counter Diseases Examinations ... Medicines Frames not supported Frames not supported HOTLINKS Health shop Health forum Health amd Nutrition Diseases ... A What is the cause of the antiphospholipid syndrome? What types of antiphospholipid syndrome exist? When only the symptoms of the antiphospholipid syndrome occur, this is known as primary antiphospholipid syndrome. The secondary form occurs in association with another autoimmune disease, usually systemic lupus erythematosus. Both types are more common in women. What are the symptoms of antiphospholipid syndrome? The symptoms relate to abnormal clotting. Most commonly clots can develop in the veins of the legs (deep vein thrombosis), resulting in a swollen, painful leg, with the swelling usually starting in the calf. These clots in the leg may happen once, or several times. Clots may also occur in the lung (pulmonary embolus), sometimes following a clot in the leg, which breaks off and travels in the circulation until it lodges in part of the blood supply to the lung. A clot in the lung may lead to shortness of breath, chest pain made worse by breathing in, or coughing up a small amount of blood. Some clots occur in patients soon after starting on the oral contraceptive pill (oestrogen-containing types).

94. The Antiphospholipid Syndrome (Hughes' Syndrome) Further information on antiphospholipid syndrome (hughes syndrome) Website www.hughessyndrome.org. A patient booklet can be obtained from Lupus UK, http://www.tiscali.co.uk/lifestyle/healthfitness/health_advice/netdoctor/archive

// Show bread crumbs navigation path. breadcrumbs('five'); //> From: www.tiscali.co.uk/lifestyle/ Calculators Calorie Counter Diseases Examinations ... Medicines Frames not supported Frames not supported HOTLINKS Health shop Health forum Health amd Nutrition Diseases ... A (Contd) Treatment of antiphospholipid syndrome Patients with antiphospholipid syndrome who have recurrent miscarriages can also be treated, but not with warfarin as it has the potential to cause foetal abnormality if given during pregnancy. Treatment of such patients is with either aspirin, or another anticoagulant, heparin. Sometimes both are used. Heparin needs to be given daily during pregnancy by injection under the skin. Patients are usually taught how to do this, and most manage without difficulty. It can also be given by nurses. Unlike warfarin, there are no blood tests usually required to monitor heparin treatment. At present the recommended treatment is low dose aspirin, providing there are no contraindications. Some patients have positive antiphospholipid antibody tests, but have never had a thrombosis or a miscarriage. Research into the best treatment for such patients is currently being carried out. At present, the recommended treatment is low dose aspirin. Aspirin acts on platelets (small blood cells involved in forming clots) to reduce their stickiness, and hence reduces the ability of the blood to clot. Living with antiphospholipid syndrome Patients should also reduce their risk of thrombosis from causes other than the antiphospholipid syndrome. They should stop smoking, make sure they are a healthy weight, and take regular exercise. The doctor will assess their other risk factors for thrombosis - by measuring their blood pressure to rule out

95. Discovery Home & Health Website Further information on antiphospholipid syndrome (hughes syndrome). Website www.hughessyndrome.org. A patient booklet can be obtained from Lupus UK, http://www.discoveryhealth.co.uk/encyclopaedia/default.asp?cat=Pregnancy&storyid

96. Hughes' Syndrome (www.whonamedit.com) hughes syndrome A common autoimmune prothrombotic disease characterised by an increased tendency to form thromboses. http://www.whonamedit.com/synd.cfm/3361.html

Home List categories Eponyms A-Z Biographies by country ... Contact Whonamedit.com does not give medical advice. This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor. A recommendation: Hypography is an open community about science and all things related Hughes' syndrome Synonyms: Antiphospholipid syndrome: APS, sticky blood syndrome. Associated persons: Graham Robert Vivian Hughes Description: A common autoimmune prothrombotic disease characterised by an increased tendency to form thromboses. Any blood vessel can be affected, including the veins and the arteries, causing increased risk of suffering a stroke or heart attack. Some clots occur in patients soon after starting on the oral contraceptive pill (oestrogen-containing types). In pregnancy, the placenta can be affected by small clots preventing vital nutrients getting to the baby, and there is an increased risk of miscarriage, particularly in mid or late pregnancy. The disorder can affect both men and women, from adolescence to hight age. Neurological complications include headaches and sometimes diplopia, memory loss, ataxia, and "multiple sclerosis-like" features. Because of these features the disorder can be mistaken for multiple sclerosis or early onset Alzheimer's disease.

97. Full Text: Editorial Anticardiolipin Test and the Antiphospholipid (hughes) syndrome 20 Years hughes pointed out that the syndrome could occur in patients who did not have http://www.jrheum.com/subscribers/04/11/2099.html

Search the Journal Home Current Issue Archives Guidelines for Authors ... Contact Info Editorial Anticardiolipin Test and the Antiphospholipid (Hughes) Syndrome: 20 Years and Counting! E. NIGEL HARRIS, MPhil, MD, DM, Download PDF View Table of Contents Professor of Medicine, Vice Chancellor, University of the West Indies, Mona, Kingston 7, Jamaica; MUNTHER KHAMASHTA, MD, FRCP, Consultant Physician, Lupus Research Unit, The Rayne Institute, St. Thomas' Hospital, London, UK. Address reprint requests to Dr. Harris. It has been 20 years since The Lancet published the first report on the anticardiolipin (aCL) test that identified a group of patients subject to recurrent arterial and/or venous thromboses and recurrent pregnancy losses (RPL). It spawned a wave of interest in what came to be known as the antiphospholipid syndrome (APS). . This was initially called the aCL syndrome, but as aCL were found to cross-react with other negatively charged phospholipids, it came to be known as the antiphospholipid (aPL) syndrome . Hughes pointed out that the syndrome could occur in patients who did not have systemic lupus erythematosus, and introduced the term primary APS for non-lupus patients at the British Society for Rheumatology meeting in 1987. The interest this subject has generated has amazed even the most optimistic of the original coauthors of the first Lancet in vivo clotting abnormality called the lupus anticoagulant (LAC). The term LAC is paradoxical, since it actually prolonged clotting

98. Antiphospholipid Syndrome (Hughes' Syndrome) APS Thromboses Acupuncture And Chin Antiphospholipid syndrome (hughes syndrome) Acupuncture and APS thromboses Antiphospholipid syndrome chinese Herbal Medicine Centre body s immune system http://www.geocities.com/mastertole/Hughes.html

The Tole Institute of Acupuncture and Herbal Medicine Our New Medical Centre and Institute is offiacially opended by our Health Minister in 1993, January 31th. Y.A.B Dato. Lee Kim Sai. Antiphospholipid syndrome (Hughes' syndrome) Antiphospholipid syndrome (APS) is sometimes called 'sticky blood syndrome'. This is because people with it have an increased tendency to form clots in blood vessels (also known as thromboses). Any blood vessel can be affected including the veins, which are thin walled and take blood towards the heart, and the arteries, which have thick muscular walls, and take blood away from the heart. As a result of this clotting tendency these patients may develop repeated clots, eg in the veins of the leg (deep vein thrombosis), or in the arteries supplying the brain, causing a stroke. In pregnancy, the placenta can be affected by small clots, and there is an increased risk of miscarriage, particularly in mid-pregnancy. Causes The 'antiphospholipid antibodies'. Antibodies are produced by the body's immune system to fight infection from bacteria and viruses. In some diseases, the immune system produces antibodies that mistakenly attack the body's own tissues. The result is an autoimmune disease, eg antiphospholipid syndrome. Phospholipids are phosphorus-containing fat molecules found throughout the body, particularly in the surrounding coat of cells - the cell membranes. The 'antiphospholipid antibodies' target the body's own phospholipids, and also proteins that bind to phospholipids.

99. About Thrombosis: Thrombophilia: Acquired Thrombophilia: APS Antiphospholipid or hughes syndrome. Antiphospholipid syndrome (APS) results from the It is also known as hughes syndrome, after Dr Graham hughes, http://www.thrombosis-charity.org.uk/aboutthrom_thrombophilia_acquired_aps.htm

site map home contact us About thrombosis ... Acquired thrombophilia Antiphospholipid syndrome Myeloproliferative disorders Paroxysmal nocturnal haemoglobinuria Hyperhomocysteinaemia Antiphospholipid or Hughes' syndrome Antiphospholipid syndrome (APS) results from the presence of antiphospholipid antibodies in the blood, combined with a previous thrombosis, specific problems during pregnancy, or both. It is also known as Hughes' syndrome, after Dr Graham Hughes, who first described the condition in the British Medical Journal in 1983. Hughes, GRV . Thrombosis, abortion, cerebral disease and lupus anticoagulant. BMJ APS and thrombosis Unlike the other thrombophilias, which tend to cause venous thrombosis , antiphospholipid antibodies can also lead to arterial thrombosis or thrombosis in small blood vessels. Once someone with APS has had a thrombosis, further thromboses tend to occur in the same area. For example, if an individual has had a stroke, they will tend to have further strokes; if they have had a deep vein thrombosis, they will tend to have furt her DVT.

100. Antiphospholipid Syndrome (APS) Antiphospholipid syndrome (APS, hughes syndrome) is a systemic Anticardiolipin Test and the Antiphospholipid (hughes) syndrome 20 Years and Counting! http://www.sclero.org/medical/symptoms/associated/antiphospholipid/a-to-z.html

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