41. Headache And Hemiplegic Migraine What is the connection between headache and hemiplegic migraine? How do I knowwhen I m in danger? Find the facts on hemiplegic migraine here. http://www.relieve-migraine-headache.com/headache-hemiplegic-migraine.html

Headache and hemiplegic migraine There's a lot of confusion when it comes to headache and hemiplegic migraine. What exactly is this rare type of migraine, and how do you know you're not dealing with something worse? Migraine, of course, is much more than just a bad headache. In fact, many migraineurs don't get headache at all ( read here for more on migraine symptoms ). Migraine symptoms tend to be different for everybody. What is hemiplegic migraine? Headache and hemiplegic migraine sometimes go together, and sometimes don't. Hemiplegia is simply paralysis on one side of the body. Someone with hemiplegic migraine has, as one of their symptoms or perhaps their only symptom, trouble moving one side of their body. Since this is a common stroke symptom, it can be frightening. The symptoms usually occur during the migraine attack and sometimes for a while afterwards. The good news is that the symptoms are only temporary, and are usually gone within 24 hours. Sometimes it affects most of the one side of the body, at other times only a part. Other symptoms may go along with it, such as difficulty speaking. There may be numbness, or a prickly feeling. Hemiplegic migraine can start in childhood or adulthood. The same person may get headaches or migraine attacks without the weakness as well. Different types of hemiplegic migraine Headache and hemiplegic migraine can be broken into a couple of catagories: *Familial Hemiplegic Migraine In this case there is a close relative (ie sibling, parent, child) that carries the same genes that cause the symptoms. It's important to give your doctor a full family history in order to diagnose Familial Hemiplegic Migraine.

42. IHC: Gene Mutation Identified For Familial Hemiplegic Migraine Type 2 Still, in 30% of families, familial hemiplegic migraine cannot be linked to eitherthat gene or a previously discovered mutation on chromosome 19. http://www.docguide.com/dg.nsf/PrintPrint/61DFDD506A261BF485256DB1004CF362

To print: Select File and then Print from your browser's menu Title: IHC: Gene Mutation Identified for Familial Hemiplegic Migraine Type 2 URL: http://www.pslgroup.com/dg/23B166.htm Doctor's Guide September 30, 2003 By Larry Schuster ROME, ITALY September 30, 2003 Italian researchers have identified a gene mutation on chromosome 1 that is associated with 10% to 20% of familial hemiplegic migraine type 2 (FHM2), according to a report presented here on September 15 th at the 11 th Congress of the International Headache Society. Giorgio Casari, PhD, department of neuroscience, San Raffaele Scientific Institute, Milan, Italy, and his research team narrowed the FHM2 locus by linkage analysis on 2 large Italian families affected by pure familial hemiplegic migraine. Dr. Casari said their research demonstrated that mutations of the alpha 2 subunit of the sodium-potassium pump are responsible for FHM2. "Functional data show that a putative pathogenetic mechanism is triggered by a loss of function of a single allele of the sodium potassium pump," Dr. Casari reported. Commenting on the report in her summary of the day's most significant papers, Marie-Germaine Bousser, MD, department of neurology, Lariboisière Hospital, Paris, France, called the presentation the "highlight of [the] day" and an "important finding" that links loss of genetic function to this inherited form of migraine.

43. Echocardiography The focal neurological deficits associated with hemiplegic migraine resemble TIAsymptoms which may occur in MVP patients. Furthermore, the risk of cerebral http://www2.umdnj.edu/~shindler/migraine.html

Migraine and Echocardiography E-chocardiography Journal: Alphabetical List Chronological List Images Home Page The migraine patient may present with aura without headache, occasionally mimicking a transient ischemic attack. The unilateral sensory loss, hemiparesis, or dysphasia may prompt referral to echocardiography to rule out a cardiac source of embolus. Migraine by B. Todd Troost, M.D. Diagnosis and Treatment of Headaches in Office Practice by David C. Haas, M.D. Frequent questions: American Council for Headache Education (ACHE) St. Anthony's Fire. A historical account of an ancient disease and it's relationship to the modern treatment of migraine. The following references discuss a possible pathophysiological relationship between migraine and mitral valve prolapse: Herman P. Migraine and mitral valve prolapse. Archives of Neurology 46(11):1165, 1989 Nov. Herman P. Migraine, large pupils, mitral valve prolapse and emotional disturbances: an autonomic disorder. Headache 27(6):340-4, 1987 Jun. Pfaffenrath V, Pollmann W, Autenrieth G, Rosmanith U. Mitral valve prolapse and platelet aggregation in patients with hemiplegic and non-hemiplegic migraine.

44. Paralysis And Hemiplegic Migraine hemiplegic migraine is a specific type of migraine. Usually, it s divided intotwo types sporadic hemiplegic migraine and familial hemiplegic migraine. http://www.sensiblesoftware.com/articles/a/Paralysis-and-hemiplegic-migraine.htm

Paralysis and hemiplegic migraine by James Cottrill Those who think of migraine as "just a bad headache" may be surprised to hear about hemiplegic migraine, a type of migraine that can involve weakness or even paralysis on one side of the body. But those familiar with migraine know that it's much more than a headache. In fact, it's often not a headache at all! Migraine attacks involve a number of symptoms. Headache is a common one, but there can also be nausea, skin sensitivity, a sensitivity to light or sound, confusion or weakness. Hemiplegic migraine is a specific type of migraine. Usually, it's divided into two types - sporadic hemiplegic migraine and familial hemiplegic migraine. BOth types are similar, the difference being that those with familial hemiplegic have a close relative that gets migraine with aura - particularly the symptom of weakness. If you've got hemiplegic migraine, either familial or sporadic, you may experience: * Sudden weakness or paralysis on one side of the body (temporary) * Numbness, a pins-and-needles prickling sensation

45. Health And Medical Information Produced By Doctors - MedicineNet.com Ask The Experts! Question Regardinghemiplegic migraine. Viewers Question.Please give me any information on hemiplegic migraine. Thank you. http://www.medicinenet.com/script/main/ques.asp?qakey=5690

46. Information Familial hemiplegic migraine usually occurs in early adolescence and the attacks hemiplegic migraine occurs in two forms, sporadic and familial, http://www.w-h-a.org/wha2/Newsite/resultsnav.asp?idContentNews=400

47. Information Familial hemiplegic migraine hemiplegic migraine occurs in two forms,sporadic and familial, both of which typically begin in childhood and cease with http://www.w-h-a.org/wha2/Newsite/print.asp?idContentNews=400

48. Migraine Types There is hemiplegic migraine, which can be inherited and has been linked to one of With hemiplegic migraine, there is often a familial occurrence. http://womenshealth.aetna.com/WH/ihtWH/r.WSIHW000/st.48340/t.48425.html

Migraine - The Basics Migraine Types The Stages Tension Headache Or Migraine? ... Resources For Headache Management Migraine Types Abdominal Migraine Basilar Migraine Complicated Migraine Cyclic Migraine Syndrome ... Status Migraine/Sterile Inflammation Abdominal Migraine The attacks are characterized by periodic bouts of abdominal pain lasting for about two hours. Along with the abdominal pain they may have other symptoms such as nausea and vomiting, flushing or pallor. Tests fail to reveal a cause for the pain. Occasionally there may be EEG findings suggestive of epilepsy but this is rarely related to seizures. Medications that are useful for treating migraine work to control these attacks in most children. Back To Top Basilar Migraine When migraine affects the circulation in back of the brain or neck, it can cause Basilar Migraine or Bickerstaff's Syndrome. It occurs most frequently in young women. Dizziness, double vision, loss of balance, confusion, slurred speech, fainting and disorientation can occur. During the acute headache, some lose consciousness. Often these patients are mistakenly thought to be intoxicated, under the influence of drugs, or suffering from other conditions. A previous history of migraine is helpful in making the diagnosis. Back To Top Complicated Migraine In all these forms, there seems to be an increased risk of the migraine producing permanent neurological changes which may also correlate with changes on the MRI scan like those seen in stroke. Medications such as the beta-blockers, triptans and ergots are often avoided in these types of headaches for fear of increasing the risk of stroke. Calcium blockers and anti-epileptic drugs seem to be best for prevention. Smoking, the use of hormones in menopause and birth control pills are avoided as well again to decrease the risk of long-term problems.

49. Familial The term familial hemiplegic migraine has been abused since in most forms ofmigraine occur and most patients with hemiplegic attacks have these http://www.dent.ucla.edu/sod/depts/oralfacial/courses/merrill/hemipleg.html

Familial Hemiplegic Migraine Description: Migraine with aura including hemiparesis and where at least one first degree relative has identical attacks. Diagnostic Criteria: A. Fulfils criteria for 1.2. B. The aura includes some degree of hemiparesis and may be prolonged. C. At least one firs degree relative has identical attacks. Comments: This disorder is marked by paralysis of the limbs on one side (hemiplegia). It may be seen as a feature of the prodromal phase and resolve as the headache appears, as with migraine. The headache is usually ipsilateral to the hemiplegia. Brainstem dysfunction is commonly observed with the headache (see Basilar Migraine). This disorder probably has the same pathophysiology as migraine with typical aura. The reason for still keeping it separate is that families have been described where attacks are strikingly identical and sometimes long lasting. The term familial hemiplegic migraine has been abused since in most families different forms of migraine occur and most patients with hemiplegic attacks have these intermingled with more frequent attacks of migraine without hemiparesis. The headache occurs in both sporadic and familial forms. Usually beginning in childhood, sometimes as early as 1-2years and generally ceasing in adulthood. The hemiplegia is usually part of the aura and may last an hour or longer. Headache follows the hemiplegia or may occur with it. There is a male predominance. CSF pleocytosis may be present (predominantly PMN's). Cerebral angiography performed during the hemiparetic attacks are usually unremarkable although constriction of the internal carotic and basilar arteries have been seen.

50. Arch Neurol -- Abstract: Hemiplegic Migraine Induced By Exertion, September 2000 Even though our patient had no family history of hemiplegic migraine, Treatment of sporadic hemiplegic migraine with calciumchannel blocker verapamil http://archneur.ama-assn.org/cgi/content/abstract/57/9/1363

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 57 No. 9, September 2000 Featured Link E-mail Alerts Observation Article Options Full text PDF Send to a Friend Readers Reply Submit a reply Related articles in this issue Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Razavi M Adams HP Articles that cite this article ISI Web of Science (6) ... Contact me when this article is cited Topic Collections Headache Migraine Topic Collection Alerts Hemiplegic Migraine Induced by Exertion Mehrdad Razavi, MD Behzad Razavi, MD Deema Fattal, MD Adel Afifi, MD Harold P. Adams, Jr, MD Arch Neurol. It is known that exertion can aggravate migraine headache. However, the relationship between exertion and migraine aura is unknown. To study the relationship between exertion and migraine aura.

51. Arch Neurol -- Familial Hemiplegic Migraine, May 2003, Koeppen 60 (5): 663 Familial hemiplegic migraine. Arch Neurol. 2003;60663664. features ofpatients with familial hemiplegic migraine (FHM) in 5 unrelated families. http://archneur.ama-assn.org/cgi/content/extract/60/5/663

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 60 No. 5, May 2003 Featured Link E-mail Alerts Editorial Article Options Full text PDF Send to a Friend Readers Reply Submit a reply Related articles in this issue Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Koeppen AH Contact me when this article is cited Topic Collections Headache Migraine Topic Collection Alerts Familial Hemiplegic Migraine Arch Neurol. Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. IN THIS ISSUE of the ARCHIVES, Kors et al describe the clinical features of patients with familial hemiplegic migraine (FHM) in 5 unrelated families. They point out that a threonine-to-methionine substitution at position 666 in the polypeptide chain of the -subunit of the neuronal calcium channel (T666M) is the most frequent mutation in autosomal dominant FHM. All neurologists

52. Dummies::Identifying Variations On The Migraine Theme hemiplegic migraines are often caused by an inherited gene, but they occur With hemiplegic migraines, you experience temporary paralysis or arm and leg http://www.dummies.com/WileyCDA/DummiesArticle/id-1758.html

Add Dummies General Interest eTips to My Yahoo! My Yahoo! Home Identifying Variations on the Migraine Theme Identifying Variations on the Migraine Theme Adapted From: Migraines For Dummies As if migraines aren't big enough mischief-makers as it is, they also like to sing show tunes and take on different personas. So here we turn to migraine variants Abdominal migraines Abdominal migraines, which are sometimes diagnosed in children, are unusual because they cause pain in the stomach and lead to nausea and vomiting (sometimes without a headache). A child who complains of recurrent pain in his stomach may be experiencing abdominal migraines. Children who suffer from abdominal migraines are likely to have migraine headaches in adulthood. Abdominal migraines are usually treated with anticonvulsant drugs. Basilar migraines The basilar migraine was once known as the basilar artery migraine, or BAM. It was considered a problem that was found primarily in young women and adolescent girls, but it occurs in both sexes and all ages. Basilar migraines are extremely rare, but they have the potential to be a serious health hazard in that they can lead to a transient ischemic attack (TIA) or stroke. Symptoms to watch for are double vision, partial vision loss, terrible vomiting, dizziness, loss of balance, slurred speech, lack of coordination, numbness (on one or both sides of the body), weakness, and confusion. These symptoms typically go away at the onset of the actual headache, although they may last for days after the pain disappears.

53. Are Migraines And Bipolar Disorder Related In familial hemiplegic migraine, dysfunctional neuronal calcium channels havebeen found (1999), Familial hemiplegic migraine with cerebellar ataxia and http://www.psychiatrictimes.com/p020848.html

54. On Target - Weekly Journal, Issue July 15, 2001 Familial hemiplegic migraine is an autosomal dominant disorder characterized by It is divided into pure familial hemiplegic migraine (affecting 80% of http://www.targethealth.com/ontarget/2001/07152001.htm

(Complimentary Newsletter from Target Health Inc.) Home Qualifications On Target Staff ... Publications July 15, 2001 Contents: I. WHAT'S NEW New Addition To Our Staff II. HISTORY OF MEDICINE James Parkinson - Child Advocate III. SUMMER SAFETY TIPS How to Avoid Stomach Distress IV. ETHICS IN CLINICAL RESEARCH Johns Hopkins Receives a 483 After a Death in a Clinical Trial V. GENETICS Familial Hemiplegic Migraine VI. NEUROLOGY Relapsing–Remitting Multiple Sclerosis (MS) VII. MICROBIOLOGY Drug Resistance and Duration and Intensity of Treatment VII. FDA Clinical Trials of Serious or Life-Threatening Conditions TARGET HEALTH I. WHAT'S NEW back to top New Addition To Our Staff TARGET HEALTH is pleased to announce the appointment of Mr. Joonhyuk Choi as Data Analyst/Programmer to our growing Target e*CRF ™ development team. Mr. Choi holds a degree in Electrical and Computer Engineering and will answer directly to our Chief Technology Officer, Joon You. Other members of the Target e*CRF ™ team include Yong Joong Kim, Laura Suciu, and Kevin Kim. We know that we have the best and most user-friendly Internet-based data collection, retrieval and project management system in the Industry. For more information contact julesmitchel@targethealth.com

55. Headaches And Migraine: Easing The Pain -- Seymour Diamond, MD this is a hereditary factor, and the hemiplegic migraine runs in their family.Only rarely will hemiplegic migraine progress to a permanent stroke. http://my.webmd.com/content/article/66/79820

WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map You are in All Conditions ADD/ADHD Allergies Alzheimer's Arthritis Asthma Back Pain Bipolar Disorder Breast Cancer Cancer Cholesterol Management Dental Depression Diabetes Epilepsy Eye Health Heart Disease Hepatitis HIV/AIDS Hypertension Men's Conditions Mental Health Migraines/Headaches Multiple Sclerosis Osteoporosis Parkinson's Sexual Conditions Stroke Weight Control Women's Conditions This article is from the WebMD Live Events Transcript Archive Headaches and Migraine: Easing the Pain Seymour Diamond, MD WebMD Live Events Transcript In recognition of National Headache Awareness Week 2003, we asked for pain prevention and treatment tips from neurologist Seymour Diamond, MD, director of the Diamond Headache Clinic. The opinions expressed herein are the guest's alone and have not been reviewed by a WebMD physician. If you have questions about your health, you should consult your personal physician. This event is meant for informational purposes only. Member: Is there a way to tell the difference between a migraine and a regular headache?

56. Migraines During Childhood & Adolescence Familial hemiplegic migraine.(vii) This rare variant is Migraine with auraincluding hemiplegia or hemiparesis. At least one first degree relative has http://www.migraines.org/treatment/treatkid.htm

"Seraphim" Dancing With Migraine Disease As A Youth By Michael John Coleman I still remember clearly the first time a Migraine disrupted my life, I was just six years old and in the first grade. I looked sick enough that the teacher asked me to put my head down on my desk. I still recall looking through the tall classroom windows, with the blinds drawn all the way up and dark battleship-gray fluffy-bellied clouds looming as part of an approaching autumn thunderstorm. Unbeknown to me at the time was that atmospheric pressure changes, induced by weather fronts, was a major Migraine trigger, a fact I will learn later in life. I marveled as the clouds seamed to hover over one side of the playground, and the bright and painful afternoon sunlight on the opposite side of a baseball field, a chiaroscuro effect. "USDA Roadside View" Purchase an artist hand signed giclee print of this original image and all proceeds will be donated to MAGNUM! BUY NOW To this day, dramatic skies play a dominant roll in the landscapes I produce as an artist. The pain of my Migraines throughout my life has been like being tortured by invisible terrorists. An acute severe Migraine is difficult to explain to a non-suffer. Put it this way; after enduring the so-called 'headaches,' you don't fear other things, such as dentists and bullies. But you do fear having to explain to your childhood friends why you don't want to go out to play basketball. Better to play in pain than say "I have a headache", as that just invites bullying because kids just don't understand what they have not experienced.

57. UpToDate Pathophysiology, Clinical Manifestations, And Diagnosis Of Migraine In (retinal migraine, ophthalmoplegic migraine, familial hemiplegic migraine) for migraine, with the exception of familial hemiplegic migraine (see http://patients.uptodate.com/topic.asp?file=headache/4701

58. Imigrainet.net  B. Todd Troost, M. D. hemiplegic migraine occurs both sporadically and as a familial syndrome. There have been few permanent sequelae attributed to hemiplegic migraine; http://imigraine.net/migraine/prolonged.html

In the new classification of migraine, Subtype 1.6 indicates complications of migraine. This would include all of the permanent defects discussed in this section. Focal symptoms and signs of the aura may persist beyond a headache phase. In the previous classification, this was termed complicated migraine. It is now defined by the IHS classification with two labels with increased specificity. If the aura lasts for longer than one hour but less than one week, the term migraine with prolonged aura is applied. If the signs persist for more than one week or a neuroimaging procedure demonstrates a stroke, a migrainous infarction has occurred. As pointed out previously, mid or later life the aura may not be followed by headache and has been termed migraine accompagnée or migraine associée . Migraine with aura (classic) in early reports was sometimes referred to as “ophthalmic migraine” (to be differentiated from ophthalmoplegic migraine, a subtype of migraine with aura). Migraine with aura is further reviewed under the headings: Cerebral, Ophthalmoplegic, Retinal, Basilar, and Other Varieties Cerebral A variety of cerebral symptoms may occur in migraine with aura, including motor, visual, and other sensory defects. As pointed out previously, if the aura lasts for more than one hour , but less than one week, the term migraine with prolonged aura is applied. However, if the signs persist for more than one week, or a neuroimaging procedure shows a stroke the term used is

59. Entrez PubMed Familial hemiplegic migraine is associated with at least 13 different missensemutations in the alpha1A Ca(2+) channel subunit. Some of these mutations have http://www.facultyof1000.com/pubmed/12527722

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60. Faculty Of 1000 Biology | The Familial Hemiplegic Migraine Mutation R192Q Reduce The familial hemiplegic migraine mutation R192Q reduces Gprotein-mediatedinhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic http://www.facultyof1000.com/article/12527722

Subscription Info Institutional Access Free Trial F1000 walkthrough ... About F1000 The familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cells. Melliti K, Grabner M, Seabrook GR J Physiol 2003 Jan 15 (Pt 2):337-47 "This study identifies a potential link between migraine and G..." Evaluated by Faculty of 1000 Biology member Brett Adams (Utah State University, United States) To see the full evaluation, choose from the options below: Faculty of 1000 Biology Essential, rapid post-publication evaluation of the most important papers in biology by over 1900 of the world's top scientists [see a sample evaluation You can: Customize the site and receive tailored e-mail alerts [ more "This is really going to help busy scientists find the gems amongst the mounds of rubble!" Keith Roberts (John Innes Centre, UK) Personal access Existing subscribers Log in here E-mail Password Free 7 day trial Subscribe Institutional access Recommend to your librarian 80% of the world's top institutions subscribe!

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