81. HIV And Oral Airy Leukoplakia Oral hairy leukoplakia. leuvill2.jpg (16758 byte) leuvill3b.jpg (26253 byte).top page. editor home index. http://members.xoom.virgilio.it/Aidsimaging/leucovill/Aleucovill.htm

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82. May Newsletter Vol. 1, No.1, September 1, 1998 hairy leukoplakia is a unique form of hyperkeratosis caused by the EpsteinBarr hairy leukoplakia presents as an asymptomatic white, corrugated lesion http://onepath.uthscsa.edu/news/May04.htm

Vol. 6, No. 2, May 1, 2004 AND CLINICAL CONSULTATION SERVICE Gerald Alderson, D.D.S., M.D.* Anne Cale Jones, D.D.S.* H. Stan McGuff, D.D.S.* The University of Texas Health Science Center at San Antonio Department of Pathology * Diplomates, American Board of Oral and Maxillofacial Pathology CLINICAL CORRELATION: HAIRY LEUKOPLAKIA - Dr. Anne Cale Jones Hairy leukoplakia is a unique form of hyperkeratosis caused by the Epstein-Barr virus (EBV). The majority of cases occur in individuals who are HIV seropositive. Examples have also been reported in individuals who have received solid organ transplants but are otherwise, HIV seronegative. Hairy leukoplakia presents as an asymptomatic white, corrugated lesion involving the lateral tongue. Occasional cases may involve the adjacent dorsal and ventral tongue. Although uncommon, examples of hairy leukoplakia have been reported involving other oral mucosa sites including the retromolar area and soft palate. Most cases of hairy leukoplakia are asymptomatic and are only identified following a routine oral examination. Histopathologic examination reveals hyperplastic stratified squamous epithelium covered by a thickened layer of parakeratin interspersed with occasional fungal organisms.

83. Dissident AIDS Database Cofactors, Recreational drugs, Cigarette, hairy leukoplakia. The associationbetween cigarette smoking and selected HIV-related medical conditions. http://www.rethinking.org/aids/cite/topic_145.html

Dissident AIDS Database Co-factors Recreational drugs Cigarette hairy leukoplakia The association between cigarette smoking and selected HIV-related medical conditions. Conley LJ, Bush TJ, Buchbinder SP, Penley KA, Judson FN, Holmberg SD "To clarify the effect of cigarette smoking on the development of conditions associated with HIV infection. Prospective and retrospective cohort study, with interview and examination twice a year since 1988. Data on 516 HIV-infected men from cohorts of homosexual and bisexual men in San Francisco, Denver and Chicago, who were repeatedly interviewed and examined between 1988 and 1992, were analysed. Univariate and Kaplan-Meier survival analyses were performed to assess the relationship between cigarette smoking and loss of CD4+ T-lymphocytes, diagnosis of any AIDS-defining illness, and specific diagnosis of Kaposi's sarcoma, Pneumocystis carinii pneumonia (PCP), oral candidiasis, hairy leukoplakia, and community-acquired pneumonia. Cigarette smoking was not associated with an increased likelihood or rate of developing KS, PCP or AIDS, but was associated with developing ... hairy leukoplakia in these HIV-infected men." AIDS 1996 Sep;10(10):1121-8

84. Oral Viral Lesion (Hairy Leukoplakia) Associated With Acquired Immunodeficiency Oral viral hairy leukoplakia of the tongue appears as raised white areas ofthickening on the tongue, usually on the lateral border. http://www.cdc.gov/mmwr/preview/mmwrhtml/00000607.htm

Oral Viral Lesion (Hairy Leukoplakia) Associated with Acquired Immunodeficiency Syndrome From October 1981 to June 1985, 13 (11%) of 123 patients with hairy leukoplakia (HL) seen in San Francisco, California, were additionally diagnosed as having acquired immunodeficiency syndrome (AIDS). Eighty (73%) of the 110 patients who did not have AIDS at the time of HL diagnosis were followed (1). Twenty of these developed AIDS within 1-33 months (mean 7.5 months) of HL diagnosis. Seventy-nine serum specimens from the 123 patients with HL were tested for antibody to human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by indirect immunofluorescence (2). Of these, 78 (99%) were positive. The one negative result was also negative by Western blot test. All cases met the CDC case definition for AIDS. Oral viral "hairy" leukoplakia of the tongue appears as raised white areas of thickening on the tongue, usually on the lateral border. The lesions may not respond to traditional antifungal therapy and appear to have unusual virologic features. Candida has been reported on the surface of the HL lesions. A number of viruses, including papilloma, herpes, and Epstein-Barr, have been identified by electron microscopy in biopsies obtained from the HL lesions. HL was first identified in San Francisco in 1981. The lesion has also been reported in patients examined in Los Angeles, California; Baltimore, Maryland; Ann Arbor, Michigan; Paris, France; Copenhagen, Denmark; and London, England. Reported by D Greenspan, BDS, J Greenspan, BDS, University of California, San Francisco, School of Dentistry; H Goldman, DDS, New York University Dental Center, New York City; Dental Disease Prevention Activity, Center for Prevention Svcs, CDC.

85. Pesquisa Odontológica Brasileira - Translate this page Oral hairy leukoplakia histopathologic features of the subclinical stage Oral hairy leukoplakia a histopathologic study of 32 cases. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-74912001000200005

86. Untitled hairy leukoplakia JAMA A whitish, slightly raised lesion that appears on the side of See oral hairy leukoplakia, also EpsteinBarr Virus. li Oral Hairy http://treasuresoftheinternet.org/dictionary/aids/h/ha/hairy_leukoplakia.shtml

Index: H# - HF HG - HO HP - HX HY - HZ Hairy Leukoplakia JAMA A whitish, slightly raised lesion that appears on the side of the tongue. Thought to be related to Epstein-Barr virus infection, it was not observed before the HIV epidemic. See oral hairy leukoplakia, also Epstein-Barr Virus. li> Oral Hairy Leukoplakia: SFAF a condition believed to be caused by the Epstein-Barr virus characterized by white, raised, usually painless lesions on the sides of the tongue and/or elsewhere in the mouth. Click on Sources to find source(s) of the term definition cited above (see superscript). If the term you are looking for is not included in this glossary/dictionary, search The On-Line Medical Dictionary of CancerWEB Enter word: or the Hypertext Webster Gateway Enter word: Exact Approx

87. Diagnosis Of Epstein-Barr Virus Infection In Hairy Leukoplakia By Using Nucleic Because hairy leukoplakia often presages the development of the acquired immune Oral lesions mimicking hairy leukoplakia a diagnostic dilemma. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=268272

88. The Epstein-Barr Virus EBNA-2 Gene In Oral Hairy Leukoplakia: Strain Variation, Oral hairy leukoplakia (HLP) lesions frequently contain defective EpsteinBarrvirus (EBV) Epstein-Barr virus gene expression in oral hairy leukoplakia. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=237254

89. Oral Hairy Leukoplakia Of The Lips With Cmv Retinitis In A Woman With Aids,Ganes IJDVL is an peerreviewed biomedical periodical of Indian Association ofDermatologists, Venereologists and Leprologists. http://www.ijdvl.com/article.asp?issn=0378-6323;year=1992;volume=58;issue=1;spag

90. HIV Guidelines. New York State Department Of Health AIDS Institute: Oral Health See Appendix 8A for a photographic example of hairy leukoplakia. Diagnosis oforal hairy leukoplakia in patients known to be HIV infected should be http://www.hivguidelines.org/public_html/center/clinical-guidelines/adult_hiv_gu

HOME SITE MAP ARCHIVES Clinical Guidelines ... Search this site This option available for PC users only. CRITERIA FOR THE MEDICAL CARE OF ADULTS WITH HIV INFECTION ORAL HEALTH COMPLICATIONS IN THE HIV-INFECTED PATIENT Published March 2001 * Text taken from the NYSDOH AI booklet - "Criteria for the Medical Care of Adults with HIV Infection" Download printer friendly version of this document (Requires Adobe Acrobat) Download printer friendly version of the NYSDOH AI Tables and Recommendations for this document (Requires Adobe Acrobat) Quick Find Menu The Oral Examination Medications and Oral Health HIV-Related Oral Lesions HIV-Related Periodontal Disease Salivary Gland Disease Associated With HIV Infection Human Papillomavirus Infection Appendix A References Further Reading Oral health care is a critical component of comprehensive HIV medical management. Development of oral pathology is frequently associated with an underlying progression of HIV-disease status. A thorough soft-tissue examination may reveal pathology associated with dysphagia or odynophagia. Dental problems can result in or exacerbate nutritional problems. In addition, psychosocial and quality-of-life issues frequently are associated with the condition of the oral cavity and the dentition.

91. Risk Indicators For Jointly Occurring Oral Candidiasis And Hairy Leukoplakia Occurrence of oral candidiasis (OC) and oral hairy leukoplakia (OHL) singly ortogether in HIV1 infected persons may reflect an impaired oral defense http://iadr.confex.com/iadr/2004Hawaii/techprogram/abstract_40408.htm

2989 Risk Indicators For Jointly Occurring Oral Candidiasis And Hairy Leukoplakia A. CHATTOPADHYAY , L.L. PATTON , and D.J. CAPLAN Temple University, Philadelphia, PA, USA, University of North Carolina, Chapel Hill, USA Occurrence of oral candidiasis (OC) and oral hairy leukoplakia (OHL) singly or together in HIV-1 infected persons may reflect an impaired oral defense system. Literature describing joint occurrence of these diseases is sparse. Objective: To develop an explanatory multivariable model for joint occurrence of OC and OHL. Methods: This cross-sectional study evaluated 631 adult dentate HIV-1 seropositive persons (race: White/ Black only) examined for OC and OHL from 1995 - 2000 at the University of North Carolina Hospitals in Chapel Hill, NC. Data collected from medical record review, interview questionnaires and clinical examinations were analyzed using chi-sq tests, t-tests, and ANOVA. Multivariable proportional odds models were developed, employing likelihood ratio test, using those without OC or OHL as the outcome reference group. Independent variables included: age, race, sex, sexual orientation, smoking, recreational drug use, CD4 cell count, antiretroviral medication use, and antifungal medication use. Results: m l [adj. OR (95%CI) = 13.4 (6.6, 27.2)] and CD4+ counts 200-499 cells/

92. UNC Lineberger Comprehensive Cancer Center *WebsterCyriaque J and Raab-Traub N. hairy leukoplakia An Unusual Combinationof Transforming and permissive Epstein-Barr Virus Infection. http://cancer.med.unc.edu/research/faculty/displayMember.asp?ID=226

93. Evidence For Trafficking Of Epstein-Barr Virus Strains Between Hairy Leukoplakia hairy leukoplakia (HL), an epithelial lesion found on the side of the tongue in Epstein–Barr virus intrastrain recombination in oral hairy leukoplakia. http://vir.sgmjournals.org/cgi/content/full/83/2/317

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Abstract Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Palefsky, J. M. Articles by Greenspan, J. S. Agricola Articles by Palefsky, J. M. Articles by Greenspan, J. S. Journal of General Virology Society for General Microbiology Animal: DNA Viruses Joel M. Palefsky Jennifer Berline Deborah Greenspan and John S. Greenspan Departments of Laboratory Medicine, School of Medicine and Stomatology, School of Dentistry , and the Oral AIDS Center , University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0126, USA Author for correspondence: Joel Palefsky (at address 1). Fax +1 415 476 0986. e-mail Abstract Top Abstract Main text References Hairy leukoplakia (HL), an epithelial lesion found on the side

94. Evidence For Trafficking Of Epstein-Barr Virus Strains Between Hairy Leukoplakia hairy leukoplakia (HL), an epithelial lesion found on the side of the tongue inimmunocompromised individuals, is characterized by highlevel replication of http://vir.sgmjournals.org/cgi/content/abstract/83/2/317

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Full Text Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Palefsky, J. M. Articles by Greenspan, J. S. Agricola Articles by Palefsky, J. M. Articles by Greenspan, J. S. Journal of General Virology Society for General Microbiology Animal: DNA Viruses Joel M. Palefsky Jennifer Berline Deborah Greenspan and John S. Greenspan Departments of Laboratory Medicine, School of Medicine and Stomatology, School of Dentistry , and the Oral AIDS Center , University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0126, USA Author for correspondence: Joel Palefsky (at address 1). Fax +1 415 476 0986. e-mail Hairy leukoplakia (HL), an epithelial lesion found on the side

95. Oral Hairy Leukoplakia Is Not A Specific Sign Of HIV Infection But Related To Im Oral hairy leukoplakia is not a specific sign of HIV infection but related toimmunosuppression in general. J Oral Pathol Med 1989182831. http://www.uku.fi/wwwdata/julkaisutoiminta/julkaisut/1989/8900472.html

Julkaisu Reference Syrjänen S, Laine P, Niemelä M, Happonen RP. Oral hairy leukoplakia is not a specific sign of HIV infection but related to immunosuppression in general. J Oral Pathol Med Julkaisutiedot Julkaisutyyppi: Alkuperäisartikkeli. Kansainvälinen. Publication data Publication type: Original scientific article. International. Tekijät Contributors Kuopion yliopisto Kliinisen patologian ja oikeuslääketieteen laitos Suupatologian, röntgenologian ja oikeushammaslääketieteen laitos University of Kuopio Department of Pathology and Forensic Medicine Department of Oral Pathology, Roentgenology and Forensic Odontology Julkaisutietokanta Publications Data Base

96. PAST QUESTIONS - Mouth Matters My doctor has told me that I have hairy leukoplakia. (I didn t ask her abouthairy leukoplakia) The premise is that the positive probiotic yogurt http://www.geocities.com/~jenniferjensen/QUESTIONS/mouth.htm

Past Ques tions Mout h Mat ters Ask a New Question and/or Read More Past Questions Or R etur n to: Q Hairy Leukoplakia My doctor has told me that I have hairy leukoplakia. I have tried a pridex rinse but it did not help. If you have any other suggestions please let me know. A: Barbara Scott, MPH, RD responds: Administrator's note: For some additional tips check out Jennifer's article The Mouth:Its Care and Feeding Q Perleche What is perleche? Is it related to yeast or thrush? A: Charlie Smigelski, RD responds: Administrator's Note: According to Taber's Cyclopedic Medical Dictionary , perleche is a "disorder marked by fissures and epithelial desquamation at corners of the mouth, esp. seen in children. May be due to oral candidiasis or may be a symptom of dietary deficiency, esp. riboflavin deficiency.") As noted in the above definition, perleche is often associated with the growth of Candida/yeast cells in the corner of the mouth. Since Candida has been modestly correlated with low selenium levels, I would encourage you to check your supplement intake and be sure you are getting 200 mcg of selenium a day. I recall a conversation with Jennifer when she advocated 400 mcg or more a day. I do suggest the higher amounts for Hep C poz people. Hep C is an RNA virus whose growth is sensive to selenium/glutathioone deficiencies. B vitamin deficencies (like riboflavin) also produce cracks in the corner of the mouth. This is different in its cause from the yeast-generated condition, but obviously a good B Complex vitamin is in order. I often recommend a Complex 25 or a Complex 50 to get enough.

97. Normal Oral Epithelium Supports Persistent EBV Infection In HIV-Infected Patient One of the subjects had hairy leukoplakia, while the other did not. The findingthat hairy leukoplakia and normal tissues demonstrated similar EBV http://www.hivandhepatitis.com/recent/ois/010402d.html

Normal Oral Epithelium Supports Persistent EBV Infection in HIV-Infected Patients NEW YORK (Reuters Health) - The normal oral epithelium of HIV-infected patients can support persistent Epstein-Barr virus (EBV) infection. However, while productive EBV replication is needed for oral hairy leukoplakia to occur, it is not sufficient by itself, according to a report in the December 15th issue of The Journal of Infectious Diseases Dr. Dennis M. Walling, from the University of Texas Medical Branch at Galveston, and colleagues assessed EBV replication in tongue biopsy specimens from two HIV-infected patients who were treated with valacyclovir. Specimens were obtained before treatment, on day 28 of treatment, and 28 days after discontinuing treatment. One of the subjects had hairy leukoplakia, while the other did not. The researchers found evidence of EBV replication in both hairy leukoplakia and normal tongue tissues. Valacyclovir treatment completely eradicated EBV replication and led to resolution of hairy leukoplakia in the affected patient. After treatment discontinuation, EBV replication in normal epithelial cells returned in both patients. The finding that hairy leukoplakia and normal tissues demonstrated similar EBV replication levels suggests that other cofactors are needed for the development of hairy leukoplakia. "Identification of these cofactors...could have implications for understanding EBV pathogenesis in other EBV-associated epithelial diseases, such as nasopharyngeal carcinoma," the authors note.

98. Oral Complications Of HIV Infection - New Treatments, January 22, 2005 We have shown that both oral candidiasis and hairy leukoplakia predict the First seen on the tongue in homosexual men, hairy, leukoplakia has since been http://www.medical-library.org/journals2a/Oral_HIV.htm

Click here to view next page of this article Oral Complications of HIV Infection Oral lesions often occur in HIV and are reflections of reduced immune function manifested as oral opportunistic conditions, which are often the earliest clinical features of HIV infection. Some, in the presence of known HIV infection, are highly predictive of the ultimate development of the full syndrome Oral lesions seen in association with HIV infection are classified in Table 12-1, and our general approach to the diagnosis and management of oral HIV disease is summarized in Table 12-2 Candidiasis The pseudomembranous form of oral candidiasis (thrush) was described in the first group of AIDS patients and is a harbinger of the full-blown syndrome in HIV-seropositive individuals. We have shown that both oral candidiasis and hairy leukoplakia predict the development of AIDS in HIV-infected patients independently Table 12-1. Oral Lesions in HIV Infection Fungal Candidiasis Pseudomembranous Erythematous Angular cheilitis Hyperplastic Histoplasmosis Geotrichosis Cryptococcosis Aspergillosis Bacterial HIV-associated gingivitis HIV-associated periodontitis Necrotizing stomatitis Mycobacterium avium complex Klebsiella stomatitis Bacillary angiomatosis Viral Herpes simplex Herpes zoster Cytomegalovirus ulcers Hairy leukoplakia Warts Neoplastic Kaposi's sarcoma Non-Hodgkin's lymphoma Squamous cell carcinoma (?)

99. Oral Manifestations Of HIV-AIDS Oral hairy leukoplakia ORAL hairy leukoplakia ORAL hairy leukoplakia Oral hairy leukoplakia Oral hairy leukoplakia Oral hairy leukoplakia http://www.anpa.org/conference/hivt/

Oral Manifestations of HIV-AIDS June 1997 Click here to start Back to ANPA home Table of Contents Oral Manifestations of HIV-AIDS Update on the Pathogenesis of HIV Immunopathogenesis Candidiasis ... HIV INFECTION CONTROL PROTOCOL Author: Dr. Oluwole Ajagbe Dept. of Maxillofacial Pathology Howard University College of Dentistry

100. Project Inform's HIV And The Mouth [ HIV / AIDS Treatment Information ] These conditions, like candidiasis and hairy leukoplakia, Oral hairyleukoplakia (OHL), believed to be caused by the same virus that causes http://www.projinf.org/fs/oral.html

Search Contact Us Feedback Calendar ... Site Map HIV and the Mouth January 2001 View PDF (Spanish Translation) Table of Contents Starting and Keeping Good Oral Health Brushing Toothbrush and Toothpaste Dental Floss ... Oral Conditions Chart Taking care of your mouth and teeth is a very important, yet often overlooked, part of maintaining general health. Good oral health can help you prevent or catch infections early. It can also give you clues as to the state of your overall health and your immune system. Starting and Keeping Good Oral Health Brushing Toothbrush and Toothpaste Dentists recommend toothbrushes with soft bristles because hard ones can cause the gums to bleed and recede, leaving unprotected areas prone to infection. Toothbrushes should be replaced every month or two. The most important consideration regarding toothpaste is whether or not it contains fluoride. Aside from that, specific brands are more of a personal choice and needs. Table of Contents Dental Floss Mouthwash Using a mouthwash at least twice a day can add fluoride to your teeth, kill bacteria often responsible for bad breath, reduce plaque which can cause cavities and prevent gum disease. Many prescription and over-the-counter mouthwashes are effective, but most of them contain up to 25% alcohol. Since this amount of alcohol can cause a painful burning sensation, some may find it necessary to use an alcohol-free rinse. Most alcohol-free mouthwashes are as effective as those with alcohol.

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