41. Webcare - Kidney/Glomerular Diseases Many diseases affect kidney function by attacking the glomeruli, glomerular diseases include many conditions with a variety of genetic and environmental http://www.webcare.md/Index747.aspx

Health Information Living Healthy Products Site Map ... Diseases and Conditions Articles : Kidney/Glomerular Diseases Glomerular Diseases Many diseases affect kidney function by attacking the glomeruli, the tiny units within the kidney where blood is cleaned. Glomerular diseases include many conditions with a variety of genetic and environmental causes, but they fall into two major categories: Kidney Stones in Adults Kidney stones, one of the most painful of the urologic disorders, are not a product of modern life. Scientists have found evidence of kidney stones in a 7,000-year-old Egyptian mummy. Unfortunately, kidney stones are one of the most common disorders of the urinary tract; patients made more than 1.3 million visits to health care providers to have their stones treated in 1997. In 1999, more than a quarter million hospitalized patients had a diagnosis of kidney stones. An estimated 10 percent of people in the United States will have a kidney stone at some point in their lives. Men tend to be affected more frequently than women. Your Kidneys and How They Work Your two kidneys are vital organs that perform many functions to keep your blood clean and chemically balanced. Understanding how your kidneys work can help you to keep them healthy.

42. Florida State University College Of Medicine Digital Library glomerular diseases Clinical Resources by SubTopic For other glomerular diseases Sub-Topics, go to General Nephrology Clinical Resources http://fsumed-dl.slis.ua.edu/clinical/nephrology/glomerulonephritis/

Clinical Resources by Topic: Nephrology Glomerular Diseases Clinical Resources See also: Nephrological Clinical Procedure Resources Glomerular Diseases Patient/Family Resources General Nephrology Clinical Resources Glomerular Diseases Clinical Resources by Sub-Topic: Acute Glomerulonephritis Chronic Glomerulonephritis Glomerulopathies Associated with Multisystem Diseases Nephrotic Syndrome ... Rapidly Progressive Glomerulonephritis For other Glomerular Diseases Sub-Topics, go to General Nephrology Clinical Resources Medical Library Florida State University College of Medicine Service provided by the Clinical Digital Libraries Project of the UA and UNT Schools of Library and Information Studies Powered by UA Digital Libraries Navigation Lab technology

43. Florida State University College Of Medicine Digital Library General Nephrology Patient/Family Resources. glomerular diseases Patient/Family Resources by SubTopic. Acute Glomerulonephritis Chronic http://fsumed-dl.slis.ua.edu/patientinfo/nephrology/glomerulonephritis/

Patient/Family Resources by Topic: Nephrology Glomerular Diseases Patient/Family Resources See also: Autoimmune Disorders Patient/Family Resources General Nephrology Patient/Family Resources Glomerular Diseases Clinical Resources General Nephrology Patient/Family Resources Glomerular Diseases Patient/Family Resources by Sub-Topic: Acute Glomerulonephritis Chronic Glomerulonephritis Glomerulopathies Associated with Multisystem Diseases Nephrotic Syndrome ... Florida State University College of Medicine Service provided by the Clinical Digital Libraries Project of the UA and UNT Schools of Library and Information Studies Powered by UA Digital Libraries Navigation Lab technology

44. Glomerular Diseases: Part A & B Immunologic glomerular diseases. 2. Metabolic diseases (Diabetic Mellitus, Amyloidosis) B. Pathogenic mechanisms of immunologic glomerular diseases http://www.umdnj.edu/pathnweb/syspath/lec_1/gd_ab/gd_ab.htm

Home G.D.: C II. Glomerular Diseases: A. Etiologic types: 1. Immunologic glomerular diseases 2. Metabolic diseases (Diabetic Mellitus, Amyloidosis) 3. Coagulopathic disorders (DIC, Hemolytic-uremic syndrome, and Thrombotic-thrombocytopenic Purpura) (See General Path Syllabus : Thrombosis Lecture 4. Hypertension (benign and malignant) 5. Congenital/Hereditary Diseases 6. Idiopathic B. Pathogenic mechanisms of immunologic glomerular diseases: 1.Immune-complex mediated: characterized by granular capillary wall and mesangial immunofluorescent pattern of immune reactants (Ig, complement) and electron dense deposits in EM. (Fig: 3A, 3B) Fig 3A Fig 3b a.Deposition of circulating immune complexes: (Fig: 4A, 4B, 4C) Fig 4A Fig 4B Fig 4C i.Antigen exogenous (e.g., infections, drugs, foreign proteins) ii.Antigen endogenous (e.g., DNA, Ig, tumor antigens) b.In-situ immune complex formation: (Fig: 5A) Fig 5A i.Visceral epithelial cell GP330 antigen (Exp. Model: Heyman nephritis) (Fig 5B) Fig 5B ii.Planted (trapped) antigens: (Fig:5C)

45. Glomerular Diseases: Part D,E & F Primary glomerular diseases, eg, Postinfectious, Drugs, etc. 2. glomerular diseases associated with systemic diseases, eg SLE, Systemic Vasculitis, http://www.umdnj.edu/pathnweb/syspath/lec_1/gd_def/gd_def.htm

Home G.D.: C D. Pattern of injury: 1. Acute and Chronic 2. Diffuse, Focal, Segmental and Global glomerular injury 3. End stage disease E. Classification of glomerular diseases: 1. Primary glomerular diseases, e.g., Postinfectious, Drugs, etc. 2. Glomerular diseases associated with systemic diseases, e.g. SLE, Systemic Vasculitis, Coagulopathic Disorders, Neoplasia, Amyloidosis, and Diabetes Mellitus 3. Hereditary F. Clinical Syndromes: 1. Asymptomatic hematuria/proteinuria 2. Nephritic Syndrome 3. Nephrotic Syndrome 4. Hypertension 5. Acute and Chronic Renal Failure Back to Page 4 Home G.D.: C Pathology Course Menu ... UMDNJ Please direct questions and coments to Alexander G. Izaguirre izaguial@umdnj.edu

46. Glomerular Diseases - Division Of Renal Diseases And Hypertension In The Medical Curriculum in glomerular diseases Division of Renal Diseases and Hypertension in the Medical School at the University of Minnesota. http://www.med.umn.edu/renal/education/core/glom.html

Return to: Medical School Academic Health Center myAHC U of M Home ... Curriculum > Glomerular Diseases Glomerular Diseases I. Program Content A. Trainees should acquire a general understanding of the following: 1. Structure and function of the normal glomerulus and how alteration of these leads to the cardinal features of glomerular injury (proteinuria and reduced GFR); 2. The principle immunologic mechanisms causing human glomerular diseases and the features that distinguish them by immuno- fluorescence and electron microscopy; 3. The fundamental features of the normal immune response and an awareness of current concepts of autoimmunity and the factors that may be responsible for and mediate immunologic glomerular injury. B. Trainees should be familiar with and develop an in-depth knowledge of: 1. The causes, clinical decision making, and treatment of common and uncommon causes of hematuria and proteinuria. 2. Etiology and clinical findings of glomerular syndromes including nephrosis, nephritis, rapidly progressive glomerulonephritis

47. Understanding Glomerular Disease Understanding Glomerular Disease. 4/20/99 Understanding glomerular diseases Glomerular Disease Syndromes Associated with Glomerular Disease. http://www.wramc.amedd.army.mil/departments/medicine/NEPHROLOGY/education/lectur

Understanding Glomerular Disease Click here to start Table of Contents Understanding Glomerular Disease Understanding Glomerular Diseases Glomerular Disease Syndromes Associated with Glomerular Disease. ... PPT Slide Author: , MC Online Quiz on this Lecture Email: Home Page: http://www.wramc.amedd.army.mil/departments/medicine/nephro/nephrology/index.htm Download presentation source

48. Understanding Glomerular Diseases Understanding glomerular diseases. Clinical Syndromes. Morphology. Pathogenesis. Previous slide Next slide Back to first slide View graphic version. http://www.wramc.amedd.army.mil/departments/medicine/NEPHROLOGY/education/lectur

Understanding Glomerular Diseases Clinical Syndromes Morphology Pathogenesis Previous slide Next slide Back to first slide View graphic version

49. Glomerular Disease What Is Glomerular Disease? What Are the Kidneys and What Do They Do? How Do glomerular diseases Interfere with Kidney Function? http://www.icongrouponline.com/health/Glomerular_Disease.html

ICON Health Publications Official Health Sourcebooks Search ICON Health Titles: The Official Patient's Sourcebook on GLOMERULAR DISEASE (Aldosteronism With Normal Blood Pressure; Anti-glomerular basement membrane antibody disease; focal glomerulonephritis; Glomerulonephritis - pulmonary hemorrhage; Hyperaldosteronism With Hypokalemic Alkatosis; Hyperaldosteronism Without Hypertension; Hypokalemic Alkalosis with Hypercalciuria; Juxtaglomerular Hyperplasia; Lupus glomerular disease; lupus glomerulonephritis; lupus nephritis; Pulmonary renal syndrome; Rapidly progressive glomerulonephritis with pulmonary hemorrhage; Urinary potassium wasting) Revised and Updated for the Internet Age P A P E R B A C K Paperback Book Paperback Book Order by phone: 800-843-2665 (within USA) 1-201-272-3651 (from outside USA) Paperback Book Shipped in 3 to 5 business days E B O O K Electronic File * E-Book version sent via e-mail in 2 business days Pages Price $24.95(USD) ISBN Published Synopsis A comprehensive manual for anyone interested in self-directed research on glomerular disease. Fully referenced with ample Internet listings and glossary. Related Conditions/Synonyms Aldosteronism With Normal Blood Pressure; Anti-glomerular basement membrane antibody disease; focal glomerulonephritis; Glomerulonephritis - pulmonary hemorrhage; Hyperaldosteronism With Hypokalemic Alkatosis; Hyperaldosteronism Without Hypertension; Hypokalemic Alkalosis with Hypercalciuria; Juxtaglomerular Hyperplasia; Lupus glomerular disease; lupus glomerulonephritis; lupus nephritis; Pulmonary renal syndrome; Rapidly progressive glomerulonephritis with pulmonary hemorrhage; Urinary potassium wasting

50. Glomerular Diseases Glomerular Diseases IgA Nephropathy Hemolytic Uremic Syndrom glomerular diseases glomerular diseases IgA Nephropathy Hemolytic uremic syndrome Rapidly progessive glomerulonephritis. http://cnserver0.nkf.med.ualberta.ca/nephkids/glomdiseases.htm

Glomerular Diseases Glomerular diseases IgA Nephropathy Hemolytic uremic syndrome Rapidly progessive glomerulonephritis

51. DE NOVO AND RECURRENT GLOMERULAR DISEASE Many primary glomerular diseases can recur in the allograft. Before making such a diagnosis, it is necessary to exclude donor transmitted disease, http://tpis.upmc.edu/tpis/kidney/KRecDis.html

RECURRENT GLOMERULAR DISEASE Many primary glomerular diseases can recur in the allograft. Before making such a diagnosis, it is necessary to exclude donor transmitted disease, and glomerular pathology developing de novo after transplantation. The incidence and severity of disease recurrence varies with the native disease. Focal segmental glomerulosclerosis (FSGS) recurs in 30 to 50% of cases. Clinical onset of proteinuria is usually within the first few months of transplantation, and in some cases, within a few days of surgery, suggesting the involvement of a circulating factor in the pathogenesis of this disease. Graft loss occurs at a variable rate, and may be as early as within a year of diagnosis. Membranous glomerulonephritis (MGN) recurs in 25 to 50% of patients, typically a year or more after transplantation. It is associated with gradual graft loss occurring over 2-7 years. The occurrence of denovo MGN after renal transplantation should prompt investigations for Hepatitis B and C infection. A history of horse anti-thymocyte globulin therapy can be elicited in some patients. Membranoproliferative glomerulonephritis (MPGN) type 1 reportedly recurs in 30 to 40% of renal allografts. The recurrence may be asymptomatic in up to 30% of individuals, but typically leads to slowly progressive graft loss. Recurrent MPGN type 2 (dense deposit disease) has a 90% incidence of recurrence ultrastructurally: immune complex deposits can be seen in the GBM lamina densa within 6-9 months of transplantation. Approximately 30-40% of patients remain clinically asymptomatic. The remainder show 40-50% graft loss within 2 years. The light microscopic appearance in MPGN type 2 is indistinguishable from MPGN type 1.

52. Renal Glomerular Diseases: Atlas Of Electron Microscopy With Histopathological B Renal glomerular diseases Atlas of Electron Microscopy with Histopathological Bases and Immunofluorescence Findings. http://www.ascp.org/Downloadables1/WebTextItems/2235.asp

Renal Glomerular Diseases: Atlas of Electron Microscopy with Histopathological Bases and Immunofluorescence Findings

53. American Society For Clinical Pathology Renal glomerular diseases Atlas of Electron Microscopy with Histopathological Bases and Immunofluorescence Findings. Price $145.00 http://www.ascp.org/511live/timssnet/products/tnt_products.cfm?primary_id=4888&A

54. Glomerular Disease Glomerular Disease. Kidney. Glomerular Disease. glomerular diseases include many conditions with a variety of genetic and environmental causes. http://tjsamson.client.web-health.com/web-health/topics/GeneralHealth/generalhea

Kidney Glomerular Disease Glomerular diseases include many conditions with a variety of genetic and environmental causes. Glomerular Disease What is glomerular disease? Many diseases affect kidney function by attacking the tiny units within the kidney where blood is cleaned. Glomerular diseases include many conditions with a variety of genetic and environmental causes, but they fall into two major categories: Glomerulonephritis describes the inflammation of the membrane tissue in the kidney that serves as a filter, separating wastes and extra fluid from the blood. Glomerulosclerosis describes the scarring or hardening of the tiny blood vessels within the kidney. Although glomerulonephritis and glomerulosclerosis have different causes, they can both lead to end-stage renal disease What are the symptoms of glomerular disease? The signs and symptoms of glomerular disease include: Proteinuria -Large amounts of protein in the urine. (Proteinuria may cause foamy urine.) Hematuria- Blood in the urine (Blood may cause the urine to be pink or brownish.) Reduced Glomerular Filtration Rate-Inefficient filtering of wastes from the blood.

55. Pathology Education Acquired glomerular disease may develop in the kidney (primary renal disease) or as a Most glomerular diseases are mediated by the immune system. http://www.pathology.vcu.edu/education/dental2/renal.html

General Pathology 601 for Dental Students Pathology of Kidney and Collecting System 1 Section 2 Davis Massey, MD, PhD, DDS Gateway Bldg, 6th floor Office: 804-828-9739 x406 FAX: 804-828-9749 damassey@mail2.vcu.edu Objectives Terms Pathology of Glomerular Disorders ... Glomerular Diseases with Primary Hematuria Objectives Upon completion of this lecture you will be able to Describe the five syndromes clinically present in glomerular diseases List three areas of immune complex localization seen in most patients Recognize the etiology and pathogenesis, and clinical manifestations of primary glomerular diseases Recognize the etiology and pathogenesis, and clinical manifestations of renal manifestations in systemic disease Important Terms definitions Diffuse Focal Segmental Global Proliferative Exudative Membranous Mesangial Crescent Glomerulosclerosis End stage renal disease Pathology of Glomerular Disorders About 80,000 patients in the U.S. require hemodialysis for end stage renal failure (ESRD). In two-thirds of these patients ESRD resulted from a glomerular disease. The major clinical manifestations of glomerular injury include proteinuria, hypoalbuminemia, edema, hyperlipidemia, and lipiduria. Glomerular injury is usually acquired but in rare cases may have a congenital (hereditary) etiology. Acquired glomerular disease may develop in the kidney (primary renal disease) or as a secondary manifestation of a systemic disease such as lupus erythematosus (secondary renal disease). Clinical Manifestations of Glomerular Injury

56. Studiegids Transplantation immunology and glomerular diseases (UMCN, St. Radboud). Head Division of Nephrology Prof. Dr. JHM Berden. Head Nephrology Research Lab Dr. http://studiegids.science.ru.nl/2005/Master_Biology_and_Master_Medical_Biology/i

var menus = new Array('1','2','3','4','5','6', '7', '8', '9', '10'); Zoek English Studiegidsen Vakken ... Print Inhoud van deze studiegids Introduction Important addresses and telephone numbers General information The Educational Institute Biosciences Goal and final attainment levels of the academic programme Global structure of the educational programme Admission to the Master's programme Biology or Medical biology ... University awards The Master phase General Requesting approval of the master programme Biology/Medical biology Details of the master phase External traineeship at home or abroad ... Medical Microbiology/parasitology (UMCN St. Radboud) Transplantation immunology and glomerular diseases (UMCN, St. Radboud) Pathology (UMCN St. Radboud) Tumorimmunology (UMCN, St. Radboud) Gynaecologie (UMCN, St. Radboud) Hematology (UMCN St. Radboud) ... Exploring the job market Appendixes Appendix 1: Honours programme Appendix 2: Additional rules and guidelines from the Examination commission. Transplantation immunology and glomerular diseases (UMCN, St. Radboud) Head Division of Nephrology: Prof. Dr. J.H.M. Berden

57. Glomerular Diseases - Montaine Centre Of Natural Therapies - Sydney, Australia glomerular diseases glomerulonephritis signifies glomerular inflammation. http://www.montaine.com.au/enc/en_ht/ht_dt/glomerular_diseases.htm

[montaine weld/Montaine Aust/titlemenu2.htm] Encyclopaedia -> Health Topics Herbs Nutrition ... Body System The Urinary System Glomerular Diseases Clinical features Diagnosis Management Prognosis The term glomerulonephritis signifies glomerular inflammation (not infection) and can be considered as primary when the major problem appears to start in the glomerulus and secondary when involvement is part of a systemic disease. Examples of systemic disease that may cause glomerulonephritis are systemic lupus erythematosus (due to deposition of immune complexes containing DNA and anti-DNA antibodies), diabetes mellitus (due to widespread microangiopathy), chronic infections (malaria, hepatitis B, Syphilis) or certain tumours (presumably tumour antigen-antibody complexes). The introduction of percutaneous renal biopsy provided a detailed histogical classification which has further expanded following development of immuno-histological techniques (e.g., direct immunoflulorescence) and electron microscopy. It is now recognised that there is poor correlation between the clinical presentation and the histological appearance and only a few patients can be diagnosed accurately on clinical presentation. Glomerulonephritis may be classified according to pathologic changes observed on light and electron microscopy into three main groups: Minimal change glomerulopathy (no significant histolgical abnormalities present) Proliferative glomerulonephritis (proliferation of various type of cells effectively compressing the glomerular capillaries)

58. Clinical Presentations Of Glomerular Diseases Primary Glomerular Disease. IgA Nephropathy; Mesangial proliferative disease; Membranoproliferative Clinical Manifestations of Glomerular Disease http://sinoemedicalassociation.org/urosurgery/kidney diseases.htm

normal kidney This is a normal glomerulus by light microscopy. The glomerular capillary loops are thin and delicate. Endothelial and mesangial cells are normal in number. The surrounding tubules are normal. Life is good. This normal glomerulus is stained with PAS to highlight basement membranes. The capillary loops of the glomerulus are well-defined and thin. kidney glomerulus PAS- Hematoxylin Endothelial basement membrane is stained to pink with PAS # End: endothelial cells # Pod: podocytes Mes mesangial cells juxtaglomerular apparatus macula densa (MD) juxtaglomerular cells (JG cells) extraglomerular mesangium kidney glomerulus toluidine blue (epoxy resin embedding) JG cells have granules stained with toluidine blue. kidney proximal and distal tubules PAS- Hematoxylin Brush border of proximal tubules is well stained with PAS. The proximal tubules can be divide into two group (PT1, PT2). There are PAS positive granules in cytoplasm of the proximal tubules, of which brush border is strongly stained. Nucleus of distal tubules is arranged near its free surface. Basal striations of the distal tubules are well observed.

59. Karger Publishers Urinary Sediment Podocalyxin in Children with glomerular diseases We measured urine samples from children with various glomerular diseases and from http://content.karger.com/ProdukteDB/produkte.asp?Doi=74322

60. Healthfinder® — Glomerular Diseases Overview of kidney function and glomerular diseases and their causes, symptoms, and diagnosis. Includes list of definitions and pronunciations. http://www.healthfinder.gov/Scripts/ShowDocDetail.asp?doc=6507&lang=1

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