81. BioMed Central | Full Text | Fanconi Anemia Genes Are Highly Expressed In Primit fanconi anemia (FA) is a complex recessive genetic disease characterized by Since the hematopoietic defect in fanconi anemia is thought to reside in the http://www.biomedcentral.com/1471-2326/3/1

home journals A-Z subject areas advanced search ... Volume 3 Viewing options Abstract Full text PDF Associated material: Pre-publication history PubMed record Related literature: Articles citing this article on Google Scholar Other articles by authors Lafrance M ... Similar articles (PubMed) Tools: E-mail to a friend Download references Post a comment Key E-mail Corresponding author Research article Fanconi anemia genes are highly expressed in primitive CD34 hematopoietic cells Matthieu Lafrance Isabelle Brodeur Marie-Chantal Delisle and Madeleine Carreau BMC Blood Disorders The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-2326/3/1 Received Accepted Published Outline Abstract Abstract Background Methods Results ... Pre-publication history Background Fanconi anemia (FA) is a complex recessive genetic disease characterized by progressive bone marrow failure (BM) and a predisposition to cancer. We have previously shown using the Fancc mouse model that the progressive BM failure results from a hematopoietic stem cell defect suggesting that function of the FA genes may reside in primitive hematopoietic stem cells. Methods Since genes involved in stem cell differentiation and/or maintenance are usually regulated at the transcription level, we used a semiquantitative RT-PCR method to evaluate FA gene transcript levels in purified hematopoietic stem cells.

82. Fanconi Anemia Hematology and Oncology Marrow Anemia Fanconi. Fanconi s Anemia. CongenitalPancytopenia. DiamondBlackfan Anemia. Book http://www.fpnotebook.com/HEM138.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Hematology and Oncology Marrow Anemia ... Aplastic Anemia Fanconi Anemia Assorted Pages Macroglobulinemia Multiple Myeloma Myelofibrosis Polycythemia Rubra Vera ... Bone Marrow Aspiration Fanconi Anemia Fanconi's Anemia Congenital Pancytopenia Diamond-Blackfan Anemia Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Practice Management Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Hematology and Oncology Index Anemia Cancer Coagulopathy Cardiovascular Medicine Dermatology Endocrinology Otolaryngology Examination Gastroenterology Hemoglobin Hemolysis Histiocytosis HIV Infectious Disease Laboratory Leukemia General Pulmonology Lymph Marrow Neurology Obstetrics Orthopedics Pediatrics Pharmacology Platelet Prevention Procedure Psychiatry Rheumatology Sarcoma Surgery Symptom Evaluation Vascular Page Marrow Index Anemia Aplastic Anemia Fanconi Macroglobulinemia Multiple Myeloma Myelofibrosis Polycythemia Epidemiology Incidence : 1 in 60,000 to 300,000 births

83. Disability - Fanconi Anemia Links to sites with information on fanconi anemia. http://www.ilusa.com/links/disable/fanconian.htm

Fanconi Anemia Updated on June 24, 2000 HOME International Fanconi Anemia Registry (IFAR) Fanconi Anemia Research Fund We publish the FA Family Newsletter and FA Science Letter twice a year, sponsor the annual Fanconi Anemia Family Meeting, and provide telephone, e-mail, and letter support to patients and their families in 38 countries throughout the world. Fanconi Anemia Handbook! Fanconi Anemia: the Frohnmayer Family's Experience Hope for Henry - dedicated to education people about Fanconi anemia. What is Fanconi Anemia? Online Mendelian Inheritance in Man Fanconi Anemia Page Fanconi Anemia Mutation Database Stem Cell Transplantation (SCT) for Genetic Diseases - - Protocol at NIH for which some FA Patients are Eligible Hackensack University Medical Center Genetics Links Human Genome Project/National Institutes of Health Blood - The Journal of Hematology ... MedLine For books on this subject try searching the Barnes and Noble Bookstore. It's not "Books in Print" ...... But it's pretty Close! Author: Last Name First Name (Optional) Title: Keyword: Keyword Options: Do an exact match a partial match Of: all words any word this phrase Home News ILC Directory Links ... Rules INDEPENDENT LIVING USA Legal Information

84. Accessing Article fanconi anemia is characterized by congenital defects, progressive bone marrow In BRCA2defective cells, the core fanconi anemia complex is intact and http://www.nature.com/ng/journal/v36/n11/full/ng1104-1142.html

NATURE.COM NEWS@NATURE.COM NATUREJOBS NATUREEVENTS ... Help E-MAIL: PASSWORD: Save password Forgotten password? Most users gain access to full text articles through a site license. This is available to institutional customers only. For further information visit the Librarian Gateway. Full-text articles are also available through a number of other options: I want to purchase this article Select this option to view this article immediately and access it for seven days. Price: US$18* In order to purchase this article you must be a registered user. Click here to register or log in above. I want to subscribe to Nature Genetics Select this option to purchase a personal subscription. I am already a personal subscriber to Nature Genetics Personal subscribers to Nature Genetics can view this article. To do this you need to associate your subscription with your registration via the My Account page. If you already have an active online subscription, log in via the login box in the top right-hand corner of this page. You can request the document from a number of document delivery services: British Library Document Supply Centre CISTI Canadian Institute for Scientific and Technical Information Infotrieve Thomson ISI Document Delivery You can also request the document from your local library through interlibrary loan services.

85. Fanconi Anemia Gene Mutations Are Present In Young-onset Pancreatic Cancer fanconi anemia Gene Mutations Are Present In Youngonset Pancreatic Cancer.NewsRx.com. July 17, 2003. According to recent research from the United States, http://www.cancercompass.com/cancer-news/1,4979,00.htm

Search Sitemap Advanced Search Main Navigation Menu Cancer Information Cancer News Message Board My CancerCompass SM Cancer Community Cancer News Fanconi Anemia Gene Mutations Are Present in Young-onset Pancreatic Cancer Cancer News Fanconi Anemia Gene Mutations Are Present In Young-onset Pancreatic Cancer NewsRx.com July 17, 2003 According to recent research from the United States, "Genes of the Fanconi complementation groups [Fanconi anemia (FA) genes] are suggested to be involved in homologous DNA recombination and produce FA when two allelic mutations are inherited. "BRCA2 is an FA gene and additionally conveys an inherited risk for breast, ovarian, and pancreatic cancer for individuals carrying a single mutated allele [N.G. Howlett et al., Science (Wash. DC), 297: 606-609, 2002]," wrote M.S. Vanderheijden and colleagues, Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center. "Here we report inherited and somatic mutations of FANCC and FANCG present in young-onset pancreatic cancer. This may imply a general involvement of Fanconi genes with an inherited risk of cancer. The known hypersensitivity of Fanconi cells to mitomycin and other therapeutic agents [M. S. Sasaki, Nature (Lond.), 257: 501-503, 1975] suggests a therapeutic utility for a more complete characterization of the DNA repair defects and their causative genetic mutations in pancreatic cancer," the researchers concluded. Vanderheijden and colleagues published their study in Cancer Research (Fanconi anemia gene mutations in young-onset pancreatic cancer. Cancer Res, 2003;63(10):2585-2588).

86. A To Z Encyclopedia Topic Fanconi Anemia fanconi anemia (FA) is a rare disease characterized by multiple physical The Comprehensive fanconi anemia Center at Dana Farber Cancer Institute Boston http://web1.tch.harvard.edu/cfapps/A2ZtopicDisplay.cfm?Topic=Fanconi Anemia

87. Fanconi Anemia | Www.somethingjewish.co.uk fanconi anemia is a blood disorder characterized by pancytopenia (deficiency of red The majority of individuals with fanconi anemia are diagnosed during http://www.somethingjewish.co.uk/articles/366_fanconi_anemia.htm

HOME CONTACT US JOIN OUR FREE MAILING LIST JEWISH BLOGS ... WORLD NEWS SEARCH Home Page About Us Register with us Fun Stuff ... Suzie Gold Last Updated: >>More from SJ Health E-mail this to a friend Fanconi Anemia Fanconi anemia is a blood disorder characterized by pancytopenia (deficiency of red blood cells, white blood cells and platelets), increased risk for cancer, and congenital birth defects. The disease is highly variable and is frequently associated with cardiac, kidney and limb abnormalities. Short stature is commonly observed in children and adults with Fanconi anemia, and other growth measurements may also be below normal. Bleeding episodes and bruising are common, as are hormonal problems and infertility. The majority of individuals with Fanconi anemia are diagnosed during childhood, but many do not survive beyond young adulthood. This is frequently a result of leukemia or other cancers, which are due to bone marrow failure. Treatment for Fanconi anemia is primarily preventive. Individuals with Fanconi anemia may pursue bone marrow transplantation on an experimental basis, however there is to date no consistently effective treatment. In order to detect cancers early, individuals with Fanconi anemia should arrange for frequent screenings. In addition, avoidance of sun exposure and other agents which may damage the chromosomes is imperative. Although five subtypes of Fanconi Anemia exist, it is only Type C that occurs with increased frequency among individuals with Ashkenazi Jewish ancestry. It is estimated that approximately 1 in 89 Ashkenazi Jewish individuals are carriers of Type C. All types of Fanconi anemia are inherited in an autosomal recessive manner. Therefore parents of an affected child have a 1 in 4 (25%) chance in each future pregnancy to have another child with Fanconi anemia.

88. Fanconi Anemia Gene Nomenclature A fanconi anemia (FA) gene – when mutated at both alleles – causes Fanconi Approved fanconi anemia gene symbols assigned or reserved as of November 2004 http://www.gene.ucl.ac.uk/nomenclature/genefamily/fanconi.html

HGNC Gene Family Nomenclature Fanconi anemia gene nomenclature Definition A Fanconi anemia (FA) gene – when mutated at both alleles – causes Fanconi anemia, a rare autosomal recessive disease with diverse symptoms. Because the clinical symptoms vary considerably and/or may be absent altogether, the FA diagnosis depends on a positive chromosomal breakage test in which cells are exposed to a cross-linking agent such as diepoxybutane or mitomycin C. Please click to link below for details of approved symbols The gene symbols for FA genes carry the root FANC #, followed by a letter, to be assigned in alphabetical order in order of discovery. If a gene with an existing approved symbol is identified as a FA causing gene, the original gene symbol is usually maintained and an appropriate FANC # gene symbol may be assigned as an alias. Genes encoding proteins that are supposed to function in the FA pathway, but without any patients identified to date who carry mutations in these genes, will have symbols with the root FAAP (for Fanconi anemia associated protein) followed by a number. The number is assigned in order of discovery and reservation is made prior to publication (subject to gene sequence submission) with the HUGO Gene Nomenclature Committee.

89. Short Description Of Cell Lines. Pathology: Fanconi Anemia Pathology fanconi anemia OMIM Home. By selecting the cell line name, you willreceive the detailed description of the cell line http://www.biotech.ist.unige.it/cldb/pat32.html

Version Short description of cell lines. Pathology: Fanconi anemia OMIM Home By selecting the cell line name , you will receive the detailed description of the cell line By selecting one of the terms between parentheses, you will receive the list of all relevant cell lines You can search any term of the list by using the 'Find' utility of your browser human, Caucasian fibroblast GGB BD-215 ... By Beatrice...

90. Fanconi Anemia (Type C), DNA Analysis This test detects ~99% of the mutations responsible for fanconi anemia, Auerbach AD, fanconi anemia Genetic Testing in Ashkenazi Jews, Genet Test, http://www.labcorp.com/datasets/labcorp/html/chapter/mono/mg003300.htm

Fanconi Anemia (Type C), DNA Analysis Number CPT Related Information Chromosome Analysis, Instability Syndrome Synonyms Jewish Heritage, IVS+4 A->T Mutation Specimen Whole blood, amniotic fluid, chorionic villus sample (CVS) (submission of maternal blood is required for fetal testing), buccal swab (The buccal swab collection kit contains instructions for the use of a buccal swab.) Volume 7 mL whole blood, 10 mL amniotic fluid, 20 mg CVS Minimum Volume 3 mL whole blood, 5 mL amniotic fluid, 10 mg CVS Container Lavender-stopper (EDTA) or yellow-stopper (ACD) tube; sterile plastic conical tube or two confluent T25 flasks for fetal testing, LabCorp buccal swab kit Storage Instructions Maintain specimen at room temperature or refrigerate. Causes for Rejection Frozen or hemolyzed specimen; quantity not sufficient for analysis; improper container Use Identification of carrier and affected individuals for one mutation, IVS4 A>T, associated with Fanconi anemia, type C. Prenatal testing is available. Limitations Methodology Allele-specific polymerase chain reaction (PCR) and gel electrophoresis References Genet Test , 1997, 1(1):27-33 (review).

91. Anemia, Fanconi's fanconi s anemia is a rare genetic disorder that may be apparent at birth orduring childhood. The disorder is characterized by deficiency of all bone http://www.bchealthguide.org/kbase/nord/nord84.htm

var hwPrint=1;var hwDocHWID="nord84";var hwDocTitle="Anemia, Fanconi's";var hwRank="1";var hwSectionHWID="nord84-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Anemia, Fanconi's Important It is possible that the main title of the report Anemia, Fanconi's is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Fanconi's Anemia, Type I (FA1) Fanconi Pancytopenia Aplastic Anemia with Congenital Anomalies Congenital Pancytopenia Constitutional Aplastic Anemia Fanconi Panmyelopathy Disorder Subdivisions Fanconi's Anemia, Complementation Group A (FANCA); FAA Fanconi's Anemia, Complementation Group B (FANCB); FACB Fanconi's Anemia, Complementation Group F (FANF); FACF Fanconi's Anemia, Complementation Group G (FANG); FACG Fanconi's Anemia, Complementation Group H (FANH); FACH General Discussion Resources March of Dimes Birth Defects Foundation 1275 Mamaroneck Avenue White Plains, NY 10605

92. HONselect - Fanconi's Anemia English, fanconi s anemia, anemia, Diamond-Blackfan - anemia, fanconi - anemia,Hypoplastic, Congenital - Diamond-Blackfan anemia http://www.hon.ch/HONselect/RareDiseases/C15.378.071.085.400.html

List of rare diseases: English Deutsch Language: MeSH term: Accepted terms: English: Fanconi's Anemia - Anemia, Diamond-Blackfan - Anemia, Fanconi - Anemia, Hypoplastic, Congenital - Diamond-Blackfan Anemia - Congenital Hypoplastic Anemia - Hypoplastic Anemia, Congenital Français: ANEMIE FANCONI - FANCONI, MALADIE Deutsch: Fanconi-Anämie - Anämie, Blackfan-Diamond- - Anämie, Fanconi- - Anämie, hypoplastische, kongenitale - Blackfan-Diamond-Anämie Español: ANEMIA DE FANCONI - ANEMIA DE DIAMOND-BLACKFAN - ANEMIA HIPOPLASTICA CONGENITA Português: ANEMIA DE FANCONI - ANEMIA DE DIAMOND-BLACKFAN - ANEMIA HIPOPLASTICA CONGENITA HONselect ressources Definition: Yes Articles: Yes Images: No News: No Conferences: No Clinical trials: Yes Web sites: English Yes Français Yes Deutsch Yes Español Yes Português No Home About us Site map Search ... Contact http://www.hon.ch/HONselect/RareDiseases/C15.378.071.085.400.html Last modified: Thu Jan 27 2005

93. NORD - National Organization For Rare Disorders, Inc. fanconi s anemia is a rare genetic disorder that may be apparent at birth or during fanconi’s anemia may also be associated with heart (cardiac), http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Anemia, Fanco

94. MedlinePlus Medical Encyclopedia: Fanconi's Anemia anemia fanconi s; FA. Definition Return to top. fanconi s anemia is an inheriteddisease that primarily affects the bone marrow, resulting in decreased http://www.nlm.nih.gov/medlineplus/ency/article/000334.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Fanconi's anemia Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Formed elements of blood Alternative names Return to top Anemia - Fanconi's; FA Definition Return to top Fanconi's anemia is an inherited disease that primarily affects the bone marrow, resulting in decreased production of all types of blood cells. The lack of white blood cells predisposes the patient to infections, while the lack of platelets and red blood cells may result in bleeding, and fatigue (anemia), respectively. It is also associated with a broad variety of physical anomalies. Fanconi's anemia is distinct from Fanconi's syndrome, a rare kidney disorder in which nutrients are lost through the urine. Causes, incidence, and risk factors Return to top Fanconi's anemia is inherited in an autosomal recessive fashion, thus one copy of an abnormal gene is passed on by each parent. It occurs in all racial and ethnic groups. It is classically diagnosed between 2 and 15 years of age. The disease is caused by a genetic defect that prevents cells from fixing damaged DNA or removing toxic, oxygen-free radicals that damage cells. Patients may be suspected of having the disease, if they have particular birth defects or develop decreased blood counts.

95. Anemia, Fanconi Definition - Medical Dictionary Definitions Of Popular Medical T Online Medical Dictionary and glossary with medical definitions. http://www.medterms.com/script/main/art.asp?articlekey=9618

96. AllRefer Health - Fanconi's Anemia (Anemia - Fanconi's, FA) fanconi s anemia (anemia fanconi s, FA) information center covers causes,prevention, symptoms, diagnosis, treatment, incidence, risk factors, signs, http://health.allrefer.com/health/fanconis-anemia-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Fanconi's Anemia Fanconi's Anemia Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : Anemia - Fanconi's, FA Definition Fanconi's anemia is an inherited disease that primarily affects the bone marrow, resulting in decreased production of all types of blood cells. The lack of white blood cells predisposes the patient to infections, while the lack of platelets and red blood cells may result in bleeding, and fatigue (anemia), respectively. It is also associated with a broad variety of physical anomalies. Fanconi's anemia is distinct from Fanconi's syndrome, a rare kidney disorder in which nutrients are lost through the urine.

97. AllRefer Health - Fanconi's Anemia Prognosis (Expectations) (Anemia - Fanconi's, fanconi s anemia (anemia fanconi s, FA) information center coversPrognosis (Expectations). http://health.allrefer.com/health/fanconis-anemia-prognosis.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Fanconi's Anemia : Prognosis of Fanconi's Anemia Fanconi's Anemia Definition Prevention Treatment Expectations or Prognosis Go To Main Page Alternate Names : Anemia - Fanconi's, FA Fanconi's Anemia Prognosis (Expectations) The reported survival of patients with Fanconi's anemia is highly varied, ranging from 2 to 25 years. The prognosis is especially poor if blood counts are low. Survival has likely been improved with the development and refinement of therapies, such as bone marrow transplantation. Although bone marrow transplantation can restore blood counts, patients with Fanconi's anemia remain predisposed to a variety of cancers (leukemia, myelodysplastic syndrome, liver cancer, and others).

98. Fanconi S Anemia,Fanconi S Anemia Type I (FA1),Fanconi fanconi s anemia,fanconi s anemia Type I (FA1),fanconi Pancytopenia,fanconi sanemia EstrenDameshek Variant,Aplastic anemia with Congenital Anomalies http://www.icomm.ca/geneinfo/fanconi.htm

99. Anemia, Fanconi's fanconi s anemia is a rare genetic disorder that may be apparent at birth orduring childhood. The disorder http://my.webmd.com/hw/anemia/nord84.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report Anemia, Fanconi's Important It is possible that the main title of the report Anemia, Fanconi's is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Fanconi's Anemia, Type I (FA1) Fanconi Pancytopenia Fanconi’s Anemia, Estren-Dameshek Variant Aplastic Anemia with Congenital Anomalies Congenital Pancytopenia Constitutional Aplastic Anemia Fanconi Panmyelopathy Disorder Subdivisions Fanconi's Anemia, Complementation Group A (FANCA); FAA Fanconi's Anemia, Complementation Group B (FANCB); FACB Fanconi’s Anemia, Complementation Group C (FANCC); FAC Fanconi’s Anemia, Complementation Group D (FANCD); FACD

100. Fanconi's Anemia Medical Information fanconi s anemia Information from Drugs.com. fanconi s anemia is an inheriteddisease that primarily affects the bone marrow, resulting in decreased http://www.drugs.com/enc/fanconi_s_anemia.html

Home New Drugs Latest News Drug Interactions ... Forum Drugs.com - prescription drug and medicine information available on over 24,000 approved- medications and pharmaceuticals, including side effects and drug interactions. Log-in Register Advertisement Buy a Link Now Special Offers From our sponsors Categories Diabetes Gastro Center Weight Loss AIDS/HIV ... Sexual Health Advertisement Advanced Search Or click the first letter of a drug name: A B C D ... Z Fanconi's anemia Injury Disease Nutrition Poison ... Formed elements of blood Fanconi's anemia Definition Fanconi's anemia is an inherited disease that primarily affects the bone marrow, resulting in decreased production of all types of blood cells. The lack of white blood cells predisposes the patient to infections, while the lack of platelets and red blood cells may result in bleeding, and fatigue (anemia), respectively. It is also associated with a broad variety of physical anomalies. Fanconi's anemia is distinct from Fanconi's syndrome, a rare kidney disorder in which nutrients are lost through the urine. Alternative Names Anemia - Fanconi's; FA

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 5     81-100 of 113    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20