61. Project: The Role Of The Epstein-Barr Virus-encoded Chemokine Receptor In Virule Titel, De rol van de door het epsteinbarr virus gecodeerde chemokinereceptor Abstract, epstein-barr virus (EBV) is a human gammaherpesvirus that causes http://www.onderzoekinformatie.nl/en/oi/nod/onderzoek/OND1297891/toon

Login English KNAW Research Information NOD - Dutch Research Database ... Research entire www.onderzoekinformatie.nl site fuzzy match Project: The role of the Epstein-Barr virus-encoded chemokine receptor in virulence and oncogenic transformation Print View Titel De rol van de door het Epstein-Barr virus gecodeerde chemokinereceptor bij virulentie en oncogene transformatie Abstract Period Related organisations Financier: NWO Council for Earth and Life Sciences Secretariat: Department of Medical Microbiology (UM) Related persons Project leader: Dr. P.S. Beisser Classification public health and health care genetics histology, cell biology microbiology ... oncology Data supplier: Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) Back NOD page Last modified: 21-07-2005 00:00

62. Project: The Role Epstein-Barr Virus-specific CG4+ T Lymphocyte Responses In The Titel, De rol van epsteinbarr virus-specifieke CG4+ T lymfocyt responsen After primary infection with the epstein-barr virus (EBV), the virus persists http://www.onderzoekinformatie.nl/en/oi/nod/onderzoek/OND1275133/toon

Login English KNAW Research Information NOD - Dutch Research Database ... Research entire www.onderzoekinformatie.nl site fuzzy match Project: The role Epstein-Barr virus-specific CG4+ T lymphocyte responses in the development of AIDS-related non-Hodgkin's lymphoma Print View Titel De rol van Epstein-Barr virus-specifieke CG4+ T lymfocyt responsen bij de ontwikkeling van aan AIDS gerelateerd non-Hodgkin lymfoom Abstract Background and purpose: T cells play a crucial role in anti-viral immunity. Both cytotoxic T-lymphocytes (CTL) and T helper (Th) cells can recognize virus-derived peptides presented by MHC molecules. After primary infection with the Epstein-Barr virus (EBV), the virus persists for life in a latent form in the B-lymphocytes. Reactivation of these latently infected B-lymphocytes is controlled by specific CD8+ CTL. HIV-infected individuals have a highly increased incidence of (EBV-positive) B cell non-Hodgkin lymphomas (AIDS-NHL). This is generally considered to be due to uncontrolled EBV-driven B lymphoproliferation because of loss of EBV-specific CD8+ T cell immunity 1. In some other viral infections it has been shown that CD4+ T cells are essential for maintenance of CTL responses and chronic control of viremia. The aim of the present project is to study the role of EBV-specific CD4+ T cell help for EBV-specific CD8+ CTL activity in HIV-1 infected individuals developing AIDS-NHL. Plan of investigation: To document the CD4+ T helper cell response against EBV in AIDS-NHL patients both quantitatively and qualitatively, the following questions will be addressed:

63. American Family Physician: Epstein-Barr Virus Infectious Mononucleosis Full text of the article, epsteinbarr virus infectious mononucleosis from American Family Physician, a publication in the field of Health Fitness, http://www.findarticles.com/p/articles/mi_m3225/is_7_70/ai_n8570308

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles American Family Physician Oct 1, 2004 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Related Searches Youth / Health aspects Teenagers / Health aspects Children / Health aspects Mononucleosis / Causes of ... Mononucleosis / Care and treatment Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Epstein-Barr virus infectious mononucleosis American Family Physician Oct 1, 2004 by Mark H. Ebell Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. Infectious mononucleosis is a clinical syndrome caused by Epstein-Barr virus (EBV) that is particularly common in adolescents and children. Typical features of infectious mononucleosis include fever, pharyngitis, adenopathy, malaise, and an atypical lymphocytosis. Splenomegaly, hepatomegaly, jaundice, and splenic rupture can occur in patients with infectious mononucleosis, but these complications are rare. (1) Data collected more than 30 years ago on the incidence of infectious mononucleosis show the highest rates in persons 10 to 19 years of age (six to eight cases per 1,000 persons per year). (2, 3) The incidence in persons younger than 10 years and older than 30 years is less than one case per 1,000 persons per year, (2, 3) but mild infections in younger children often may be undiagnosed. The infection is most common in populations with many young adults, such as active-duty military personnel and college students, in whom the annual incidence for infectious mononucleosis ranges from 11 to 48 cases per 1,000 persons. (4, 5)

64. Archives Of Pathology & Laboratory Medicine: Epstein-Barr Virus In Breast Carcin Full text of the article, epsteinbarr virus in Breast Carcinoma in Argentina from Archives of Pathology Laboratory Medicine, a publication in the field http://www.findarticles.com/p/articles/mi_qa3725/is_200503/ai_n13591275

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles Mar 2005 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Epstein-Barr Virus in Breast Carcinoma in Argentina Mar 2005 by Preciado, Mar­a Victoria Chabay, Paola Andrea De Matteo, Elena Noem­ Gonzalez, Pedro ... Et al Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. Context.-Because the etiology and progression of breast carcinoma remain unclear, novel mechanisms of disease pathogenesis need to be considered. Recent interest has focused on Epstein-Barr virus (EBV), an oncogenic ubiquitous herpesvirus. Investigations of this association could not only broaden understanding of breast cancer etiology but also have implications regarding early detection, treatment, and prevention. Objective.-To assess EBV presence in breast carcinoma in an Argentine series.

65. Epstein-Barr Virus (EBV) Protocol Information A Phase I/II Trial of Butyrate and Ganciclovir in epsteinbarr virus (EBV)-Associated Malignancies. Investigators Douglas V. Faller, Ph.D., MD http://www.bumc.bu.edu/Dept/Content.aspx?DepartmentID=109&PageID=3503

66. High Levels Of Epstein-Barr Virus Antibodies In Women Linked To Risk Of Multiple High Levels of epsteinbarr virus Antibodies in Women Linked to Risk of Multiple Sclerosis, press release of Wednesday, December 26, 2001, Harvard School of http://www.hsph.harvard.edu/press/releases/press12262001.html

Press Releases View current and archived press releases from the Office of Communications. Recent releases: Harvard Scientists Report Public Health Impact of 1990 Iraq Invasion of Kuwait: Higher Rates of Mortality Evident Among Kuwaiti Civilians Who Remained in Kuwait During Occupation press release of Wednesday, June 29, 2005 Harvard School of Public Health Student Kevin Chan Wins $160,000 Trudeau Foundation Scholarship press release of Thursday, June 23, 2005 Inner Structure of Cells Behaves Much as Molten Glass press release of Monday, June 20, 2005 Faculty Featured: Alberto Ascherio, Associate Professor of Nutrition and Epidemiology High Levels of Epstein-Barr Virus Antibodies in Women Linked to Risk of Multiple Sclerosis For immediate release: Wednesday, December 26, 2001 Boston, MA— Researchers from the Harvard School of Public Health have found that elevated levels of specific antibodies that fight a range of Epstein-Barr Virus (EBV) antigens are associated with the onset of multiple sclerosis (MS). The study results appear in the December 26, 2001 issue of the Journal of the American Medical Association (www.jama.com). Blood samples from more than 62,000 women were collected between 1989 and 1999. The researchers documented 144 cases of MS including 18 cases with blood samples collected before the onset of the disease. For each woman with MS, two without MS, who were the same age were randomly chosen as controls. Compared to their controls, the women with MS had significantly higher average blood levels of antibodies for EBV antigens before the onset of the disease. The strongest association was found for antibodies for Epstein-Barr Nuclear Antigen-2 (EBNA-2). These levels increase soon after EBV infection but normally decline within a few months. In this study, elevated levels of EBNA-2 antibodies were associated with a four-fold increase in risk of MS.

67. BioSpace News: Epstein-Barr Virus Syndrome A new study showing that antigens produced by the Epstein Barr virus may epsteinbarr virus levels in the blood may also help predict the course of http://www.biospace.com/news_rxtarget.cfm?RxTargetID=82

68. Research On Station-Reactivation Of Latent Epstein-Barr Virus ISS experiment on space flightinduced reactivation of latent epstein-barr virus. http://spaceresearch.nasa.gov/research_projects/ros/ebop.html

69. Research On Station-Reactivation Of Latent Epstein-Barr Virus ISS experiment on space flightinduced reactivation of latent epstein-barr virus. http://spaceresearch.nasa.gov/research_projects/ros/eb.html

70. EPSTEIN-BARR VIRUS ACUTE PANEL Pathology Test - Sinai Hospital Maryland epsteinbarr virus Pathology Test - Sinai Hospital Maryland. http://www.lifebridgehealth.org/22588.cfm

Return to main menu EPSTEIN-BARR VIRUS ACUTE PANEL Test Name EPSTEIN-BARR VIRUS ACUTE PANEL Synonyms EBV ANTIBODY Avail Stat? N Test Type Executable Res. Names EBV ANTIBODY Specimen Serum, Container Analysis volume: 2 ml, Red Top Processing Centrifuge, separate, refrigerate. Return to main menu

71. Opportunistic Viruses The epsteinbarr virus(EBV) has already infected a majority of the general population. epstein-barr virus-associated syndromes in immunosuppressed liver http://tpis.upmc.edu/tpis/liver/LEBV.html

Epstein-Barr Virus Introduction and Pathophysiology The Epstein-Barr virus(EBV) has already infected a majority of the general population. After an initial infection which is often asymptomatic, it lies dormant in some epithelial cells and B lymphocytes. If the infected B lymphocytes are placed in tissue culture, the absence of T cell regulatory influences allows the B cells proliferate and become "immortalized", a process hastened by the presence of immunosuppressive drugs(1-7). Viral latency in vivo is maintained by T cell immune surveillance, which keeps viral replication and B cell proliferation in check. However, the potent immunosuppressive therapy needed to assure allograft acceptance depresses immune surveillance and predisposed the recipient to EBV activation or more serious manifestations of primary infections. As with the other "opportunistic" viruses in the Herpes Virus group, the incidence of significant EBV-related disease is higher in liver allograft recipients who were seronegative before transplantation, but received an allograft from a seropositive donor(1-7). It is also more common in patients that receive heavy immunosuppression for treatment of rejection. In general, about 2% - 3% of adult recipients will develop persistent and/or recurrent disease. This can eventually result in the one of the most feared complication of EBV infection, which is development of a posttransplant lymphoproliferative disorder(1-7) or smooth muscle neoplasm(8, 9). PTLD refers to the emergence of oligoclonal and/or monoclonal B cell proliferations, that sometimes act like aggressive lymphomas(7, 10). A more detailed discussion of the pathophysiology of PTLD and the role of the Epstein-Barr virus is given in the relevant TPIS section on

72. Epstein-Barr Virus epsteinbarr virus (EBV) is a common human virus that causes infectious epstein-barr virus is in the herpes family of viruses and most people will http://ww3.komotv.com/global/story.asp?s=1230290

73. Epstein-Barr Virus epsteinbarr virus (Group 1). For definition of Groups, see Preamble Evaluation. epstein-barr virus (EBV) is a gamma-1 herpesvirus found throughout all http://www-cie.iarc.fr/htdocs/monographs/vol70/70-ebv.htm

EPSTEIN-BARR VIRUS (Group 1) For definition of Groups, see Preamble Evaluation VOL. : 70 (1997) (p. 47) 5. Summary of Data Reported and Evaluation 5.1 Virus-host interactions Epstein-Barr virus (EBV) is a gamma-1 herpesvirus found throughout all human populations, with a prevalence of over 90% in adults. Primary infection usually occurs in early childhood and is asymptomatic, whereas delayed primary infection may cause a self-limiting lymphoproliferative disease, infectious mononucleosis. Infection results in the establishment of a life-long carrier state characterized by the persistence of antibodies to several viral gene products and the secretion of infectious virus in saliva. Saliva is the usual vehicle of transmission. EBV can induce growth transformation of human and primate B-lymphocytes in vitro Cellular and perhaps humoral immune responses contribute to the control of primary EBV infection and mediate the transition to asymptomatic persistence of the virus in healthy carriers. The humoral responses include the production of neutralizing antibodies directed to the CD21-binding protein gp350/320 and antibodies directed against lytic and latent gene products. Cells expressing type-III latency, which are detected during primary infection, are promptly eliminated by CD8 major histocompatibility (MHC) class I-restricted cytotoxic T lymphocytes which recognize epitopes from all the latent viral proteins except EBNA-1. Accordingly, only EBNA-1 appears to be expressed in the latently infected B cells that persist in healthy virus carriers. The failure of this protein to elicit cytotoxic T-lymphocyte responses could be instrumental in allowing persistence of virus-infected cells in immunocompetent hosts. CD4

74. GIANTmicrobes | Kissing Disease (Epstein-Barr Virus) (EpsteinBarr), Athlete s Foot (Trichophyton mentagrophytes) Ulcer (Helicobater pylori) Pimple (Propionibacterium acnes) Giardia (Giardia lamblia) http://www.giantmicrobes.com/maladies/kissingdisease.html

A kiss is just a kiss unless she's around! 95% of the population has encountered this sweetie pie. Find out who gets her special love. Kissing Disease Plush Doll Bad Breath (Porphorymonas gingivalis) Kissing Disease (Epstein-Barr) Athlete's Foot (Trichophyton mentagrophytes) Ulcer ... (Giardia lamblia)

75. University Of Toronto -- News@UofT -- Researchers Map Role Of Epstein-Barr Virus “epsteinbarr virus (EBV) is one of the most common human viruses in the EBNA1 is a protein coded in the epstein-barr virus and suspected to play a role http://www.news.utoronto.ca/bin6/050331-1173.asp

@import "/stylesheets/newsstyle2.css"; U of T Home U of T Search My Utoronto All Websites ... Health and Medicine Researchers map role of Epstein-Barr virus in cancer Protein in virus immortalizes cells, allows them to keep proliferating March 31, 2005 by Janet Wong ( about Researchers at the University of Toronto have mapped the molecular details that show how a viral protein coded in the Epstein-Barr virus immortalizes cells and causes them to continuously grow, thereby predisposing people to certain types of cancer. ALSO SEE: other stories by Janet Wong “Epstein-Barr virus (EBV) is one of the most common human viruses in the world and is strongly linked to certain b-cell cancers like Burkitt’s lymphoma as well as the epithelial cell cancer, nasopharyngeal carcinoma. EBNA1 is a protein coded in the Epstein-Barr virus and suspected to play a role in the development of cancer,” says Lori Frappier, professor in medical genetics and microbiology at U of T and senior author of a paper in the April 1 issue of Molecular Cell “This research shows how EBNA1 interferes with natural cell growth regulation by binding to a particular protein in cells, causing them to continue growing and therefore increasing the risk of becoming cancerous.”

76. Clinical Care Options For HIV - Login HIV and epsteinbarr virus viral load were also measured, Serologic analysis indicated past epstein-barr virus infection in 7 patients, and Epstein-Barr http://clinicaloptions.com/hiv/news/news_NAM_452.asp

Home News and Comment Headlines Expert Viewpoint ... Switching to New Agents CCO Expert Recap Rio de Janeiro, Jul 2005 Retroviruses, Feb. 2005 Bangkok Jul. 2004 Washington DC, Nov. 2004 ... Guidelines Clinical Care Options Sites Main Hepatitis HIV Oncology ... Choosing and Using New Antiretrovirals for Multiclass-Experienced HIV-Infected Patients Contact the editor: hiveditor@clinicaloptions.com Advisory Board Welcome to the Clinical Care Options Site Our content is free for everyone to view, but you are required to log in as a registered user. Registration is quick and free! Not Registered Yet? Click here to REGISTER NOW Log In If Already Registered. User Name: User Password: Remember Me: Click here if you have already registered but have forgotten your User Name or Password Don't Wish to Register? To carry on unregistered for now, click here Site Requirements Advertising Policy Editorial Policy

77. Entrez PubMed The latent membrane protein (LMP1) of epsteinbarr virus (EBV) is expressed in EBV-associated nasopharyngeal carcinoma, which is notoriously metastatic. http://www.virologyj.com/pubmed/12110730

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78. Mononucleosis (Epstein-Barr Virus) Infectious mononucleosis is caused by the epsteinbarr virus (EBV), and is typically manifested by fever, exudative pharyngitis, swollen glands, http://www.in.gov/isdh/publications/2002communicable_disease_ref_guide/mononucle

Table of Contents Mononucleosis (Epstein-Barr Virus) Clinical Manifestations Infectious mononucleosis is caused by the Epstein-Barr virus (EBV), and is typically manifested by fever, exudative pharyngitis, swollen glands, and atypical lymphocytes in the blood. The spectrum of the disease is extremely variable. Infections may go unrecognized in young children, whereas, in older children and adults, clinical illness with the typical signs and symptoms are more common. Occasionally, infection may be accompanied by a rash, which is more likely to occur in people treated with Ampicillin. Complications may include aseptic meningitis, encephalitis, or Guillian-Barre syndrome. The virus is a member of the herpes-virus group. Incubation Period From 4-7 weeks after exposure. Period of Communicability Viral secretions may occur through salival exchange for many months after infection. The period of communicability is indeterminate. Applicable Laws For Indiana Schools None Applicable. School Nursing Implications Articles soiled with nose and throat discharges should be disinfected.

79. JAMA -- Abstract: Epstein-Barr Virus In Pediatric Multiple Sclerosis, April 21, Context Infection with common viruses, particularly epsteinbarr virus (EBV), has been postulated to contribute to the pathobiology of multiple sclerosis http://jama.ama-assn.org/cgi/content/abstract/291/15/1875

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 291 No. 15, April 21, 2004 Featured Link E-mail Alerts Preliminary Communication Article Options Full text PDF Send to a Friend Related articles in this issue ... Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Alotaibi S Banwell B Articles that cite this article ISI Web of Science (10) ... Contact me when this article is cited Topic Collections Immunologic Disorders Viral Infections Neurology Topic Collection Alerts Epstein-Barr Virus in Pediatric Multiple Sclerosis Suad Alotaibi, MD Julia Kennedy, MSc Raymond Tellier, MD Derek Stephens, MSc Brenda Banwell, MD JAMA. Infection with common viruses, particularly Epstein-Barr virus (EBV), has been postulated to contribute to the pathobiology of multiple sclerosis (MS). Detailed virological studies in

80. JAMA -- Abstract: Temporal Relationship Between Elevation Of Epstein-Barr Virus Notice of Retraction Multiple Sclerosis and epsteinbarr virus (JAMA. 2003;2891533-1536) Alberto Ascherio, Mark Rubertone, Donna Spiegelman, Lynn Levin, http://jama.ama-assn.org/cgi/content/abstract/293/20/2496

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 293 No. 20, May 25, 2005 Featured Link E-mail Alerts Original Contribution Article Options Full text PDF Previous Article Send to a Friend ... Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Levin LI Ascherio A Articles that cite this article ISI Web of Science (3) ... Contact me when this article is cited Topic Collections Immunologic Disorders Viral Infections Neurology Topic Collection Alerts Temporal Relationship Between Elevation of Epstein-Barr Virus Antibody Titers and Initial Onset of Neurological Symptoms in Multiple Sclerosis Lynn I. Levin, PhD, MPH Kassandra L. Munger, MSc Mark V. Rubertone, MD, MPH Charles A. Peck, MD Evelyne T. Lennette, PhD Donna Spiegelman, ScD Alberto Ascherio, MD, DrPH

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