1. Epstein-Barr Virus epsteinbarr virus and Infectious Mononucleosis. DISEASE INFORMATION. epstein-barr virus, frequently referred to as EBV, is a member of the herpesvirus http://www.cdc.gov/ncidod/diseases/ebv.htm

National Center for Infectious Diseases Epstein-Barr Virus and Infectious Mononucleosis DISEASE INFORMATION Epstein-Barr virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95% of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time. Symptoms of infectious mononucleosis are fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. Heart problems or involvement of the central nervous system occurs only rarely, and infectious mononucleosis is almost never fatal. There are no known associations between active EBV infection and problems during pregnancy, such as miscarriages or birth defects. Although the symptoms of infectious mononucleosis

2. Epstein-Barr Virus epsteinbarr virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

3. Chronic Fatigue Possibly Related To Epstein-Barr Virus -- Nevada epsteinbarr virus and unexplained illness (Letter). Ann Intern Med 1985;102722. Jones SR. epstein-barr virus and unexplained illness (Letter). http://www.cdc.gov/mmwr/preview/mmwrhtml/00000740.htm

Chronic Fatigue Possibly Related to Epstein-Barr Virus Nevada From November 1984 through August 1985, approximately 90 patients evaluated for persistent fatigue were diagnosed as having chronic Epstein-Barr virus (CEBV) disease by a two-physician community internal medicine practice near Lake Tahoe, Nevada. The diagnoses were made by detecting antibody to the diffuse (EA-D) or the restricted (EA-R) components of early antigen of EBV, as suggested by two recent studies (1,2). Because of controversy about whether CEBV disease exists, two serologic studies were conducted to evaluate whether a syndrome of chronic fatigue could be statistically associated with a specific pattern of antibody titers against EBV. Fifteen "case" patients, felt to be the most likely to have CEBV, were identified by interviewing 134 of the 139 patients tested for EBV serology in the internal medicine practice between January 1, and August 20, 1985. By definition, these patients had persistent or relapsing unexplained fatigue for at least 2 months, which forced them to stop usual daily activities for at least 2 weeks. Other less universal symptoms included intermittent low-grade fever, sore throat, myalgias, arthralgias, and headaches. All 15 patients were white; 13 were female. The median age was 40 years (range 13-52 years). In the first serologic study, the 15 patients were compared with 118 of the 119 patients who had serologic testing for EBV (the serologic test results on one patient were not available). All 118 of these patients were white; 79 (66.9%) were female. The median age was 36 years (range 10-71 years). The case patients were more likely to have reciprocal EA-D titers of 160 or higher (45.5%, compared with 11.6%; p = 0.014) and EBV viral capsid antigen IgG (VCA-IgG) 160 or greater (80.0%, compared with 51.7%; p = 0.033) in the first serum tested. No evidence of acute EBV infection, manifested by positive IgM titers to VCA, was detected in either the cases or the others tested.

4. Mononukleose Folkehelseinstituttets informasjon om virussykdommen Mononukleose/epsteinbarr virus (EBV) ogs¥ kalt Kyssesyken. http://www.fhi.no/eway/default0.asp?pid=223&oid=0&e=0&trg=Area_4504&

5. Epstein-Barr Virus-Key Text Kissing the epsteinbarr virus goodbye? Published by Australian Academy of Science Sponsored by http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. Epstein-Barr Virus-Key Text Australian research on the epsteinbarr virus has led to a glandular fever Pucker up to someone and you risk infection with the epstein-barr virus, http://www.science.org.au/nova/026/026key.htm

Key text Kissing the Epstein-Barr virus goodbye? Published by Australian Academy of Science Sponsored by Glandular fever, a common disease in teenagers, is caused by the Epstein-Barr virus. Australian research on the Epstein-Barr virus has led to a glandular fever vaccine, which is currently being trialled. You will get more from this topic if you have mastered the basics of the immune system Printer-friendly version of complete topic Like most good things in life, kissing can be hazardous to your health. Pucker up to someone and you risk infection with the Epstein-Barr virus, which causes glandular fever and other nasty diseases. But we might not have to give up kissing just yet. A vaccine currently under development in Australian laboratories could help limit the dangers posed by this sometimes deadly virus. How was the virus discovered? In 1961, a surgeon working in Uganda, Denis Burkitt, presented the results of his research to staff at the Middlesex Hospital Medical School in Britain. He reported that the incidence of a certain tumour in African children had a geographic distribution corresponding to rainfall and temperature patterns. The disease, which affects about 8 in every 100,000 children in parts of Africa and Papua New Guinea, quickly became known as Burkitt’s lymphoma. The influence of climate on its incidence seemed to suggest that some biological factor was involved. Three researchers, M.A. Epstein, Y.M. Barr and B.G. Achong, immediately began looking for possible cancer-causing viruses in samples of the tumour sent from Uganda to Britain.

7. The Center For The Biology Of Chronic Disease - Home Research center regarding epsteinbarr virus and the disease it causes. http://biologyofchronicdisease.org

Home About Nobel Donate The Book ... Contact The Center for the Biology of Chronic Disease " When we understand nature, chaos turns into order, fear into confidence, and disease into health. " -Hanan Polansky, from Microcompetition with Foreign DNA and the Origin of Chronic Disease OUR MISSION To advance the research on the biology of chronic disease To advance the discovery of a cure for chronic disease CBCD Publishing

8. The Expression And Function Of Epstein-Barr Virus Encoded Latent The expression and function of epsteinbarr virus encoded latent genes L S Young1 , C W Dawson1 and A G Eliopoulos1 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. Epstein Barr Virus-Useful Sites epsteinbarr virus – kiss this disease good-bye Provides a list of questions and answers about the Epstein Barr virus and the development of a potential http://www.science.org.au/nova/026/026sit.htm

Kissing the Eppstein-Barr virus goodbye? Useful sites Published by Australian Academy of Science Sponsored by Printer-friendly version of complete topic Cooperative Research Centre for Vaccine Technology, Australia EBV Cellular Immunotherapy Project http://www.crc-vt.qimr.edu.au/research/passiveimmunity/ebv.html Provides a list of questions and answers about the Epstein Barr virus and the development of a potential vaccine. http://www.crc-vt.qimr.edu.au/media/ebv.html Glandular fever (Better Health Channel, Australia) Glandular fever (or kissing disease) is the common term used to describe an acute viral infection called infectious mononucleosis. The virus that causes glandular fever is known as Epstein-Barr virus. Glandular fever mainly affects young adults. A chronic form of glandular fever is one of the suggested causes of chronic fatigue syndrome. http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Glandular_fever?OpenDocument The herpes virus (Australian Broadcasting Corporation) A transcript from The Health Report , 29 July 2002.

10. The Expression And Function Of Epstein-Barr Virus Encoded Latent The expression and function of epsteinbarr virus encoded latent genes L S Young1 , C W Dawson1 and A G Eliopoulos1 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. Unique Epstein-Barr Virus (EBV) Latent Gene Expression, EBNA T., Herbst, H. 8 other authors (1993). epsteinbarr virus-infected T lymphocytes in epstein-barr virus-associated hemophagocytic http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. Hardin MD : Epstein-Barr Virus From the University of Iowa s Hardin MD, Internet sources on epsteinbarr virus. http://www.lib.uiowa.edu/hardin/md/ebv.html

Epstein-Barr Virus A Hardin MD Just Plain Links Page Return to Hardin MD : Home AIDS / HIV +Pictures Autoimmune Diseases +Pictures Bells Palsy +Pictures Blood Diseases +Pictures Cancer +Pictures Chronic Fatigue Syndrome +Pictures Cold Sores +Pictures Crohns Disease +Pictures Cytomegalovirus +Pictures Dermatomyositis +Pictures Ear, Nose, Throat +Pictures Fibromyalgia +Pictures HPV +Pictures Herpes +Pictures Hives +Pictures Hodgkins Disease +Pictures Immune System +Pictures Kawasaki Disease +Pictures Lupus +Pictures Lymphoma Pictures Mononucleosis +Pictures Multiple Sclerosis +Pictures Oral Diseases +Pictures Shingles +Pictures Strep Infections +Pictures Tonsils +Pictures Toxoplasmosis +Pictures Virus Diseases +Pictures Epstein-Barr Virus Pictures Yahoo : Epstein-Barr virus Directory Epstein-Barr virus Australian Academy of Science Epstein-Barr virus and infectious mononucleosis National Center for Infectious Diseases, US Center for Disease Control (CDC) High Levels of Epstein-Barr virus antibodies in women linked to risk of multiple sclerosis Harvard Univ (Press release announcing article appearing in JAMA Dec 26, 2001) Epstein Barr virus Diana Hardie, Univ Cape Town, South Africa

13. Elevated Expression Of C-myc In Lymphoblastoid Cells Does Not Elevated expression of cmyc in lymphoblastoid cells does not support an epstein-barr virus latency III-to-I switch Alexander Pajic1 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. Epstein-Barr Virus Test epsteinbarr virus test Philadelphia WB Saunders Co., 1997. Fleischer, Gary R. epstein-barr virus. In Textbook of Human Virology. 2nd ed. http://www.healthatoz.com/healthatoz/Atoz/ency/epstein-barr_virus_test.jsp

15. Epstein-Barr Virus Infections Biology, Pathogenesis, And Management epsteinbarr virus Infections http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. EMedicine - Mononucleosis And Epstein-Barr Virus Infection : Article By Glenna B Mononucleosis and epsteinbarr virus Infection - epstein-barr virus (EBV), or human herpesvirus 4, is a gamma-herpesvirus that infects more than 95% of the http://www.emedicine.com/PED/topic705.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Infectious Diseases Mononucleosis and Epstein-Barr Virus Infection Last Updated: October 5, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: EBV, acute infectious mononucleosis, infectious mononucleosis, mono, human herpesvirus 4, HHV-4, kissing disease AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Glenna B Winnie, MD , Director, Division of Pulmonology, Associate Professor, Department of Pediatrics, University of Pittsburgh and Children's Hospital of Pittsburgh Glenna B Winnie, MD, is a member of the following medical societies: American Academy of Pediatrics American College of Physician Executives American Lung Association American Society for Microbiology ... American Thoracic Society , and Society for Pediatric Research Editor(s): Rosemary Johann-Liang, MD

17. Epstein-Barr Virus Infections Biology, Pathogenesis, And epsteinbarr virus Infections http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. MedlinePlus Medical Encyclopedia: Epstein-Barr Virus Test This is a blood test used to detect antibodies to the epsteinbarr virus (EBV) antigens. How the test is performed Return to top http://www.nlm.nih.gov/medlineplus/ency/article/003513.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Epstein-Barr virus test Contents of this page: Illustrations Alternative names Definition How the test is performed ... Special considerations Illustrations Blood test Alternative names Return to top EBV antibody test; Monospot; Heterophile agglutination test Definition Return to top This is a blood test used to detect antibodies to the Epstein-Barr virus ( EBV ) antigens. How the test is performed Return to top Blood is drawn from a vein on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding. For an infant or young child, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.

19. ABC News Epstein-Barr Virus May Boost Lupus Risk In Blacks epsteinbarr virus May Boost Lupus Risk in Blacks http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

20. Epstein-Barr Virus Infectious Mononucleosis - October 1, 2004 - American Family epsteinbarr virus and infectious mononucleosis. Accessed online August 16, 2004, Retrobulbar neuritis complicating acute epstein-barr virus infection. http://www.aafp.org/afp/20041001/1279.html

Advanced Search AAFP Home Page Journals Vol. 70/No. 7 (October 1, 2004) Epstein-Barr Virus Infectious Mononucleosis MARK H. EBELL, M.D, M.S., Athens, Georgia Patient information: A handout on infectious mononucleosis, written by the author of this article, is provided on page 1289. A PDF version of this document is available. Download PDF now (9 pages /202 KB). See page 1201 for definitions of strength-of-recommendation labels. I nfectious mononucleosis is a clinical syndrome caused by Epstein-Barr virus (EBV) that is particularly common in adolescents and children. Typical features of infectious mononucleosis include fever, pharyngitis, adenopathy, malaise, and an atypical lymphocytosis. Splenomegaly, hepatomegaly, jaundice, and splenic rupture can occur in patients with infectious mononucleosis, but these complications are rare. Data collected more than 30 years ago on the incidence of infectious mononucleosis show the highest rates in persons 10 to 19 years of age (six to eight cases per 1,000 persons per year). The incidence in persons younger than 10 years and older than 30 years is less than one case per 1,000 persons per year

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