81. NONTRAUMATIC (SPONTANEOUS) CEREBROSPINAL FLUID RHINORRHEA empty sella syndrome (ESS) is the pathological variant of a radiologically The primary empty sella syndrome analysis of the clinical characteristics, http://www.kfshrc.edu.sa/annals/201/99-037.htm

Nontraumatic (Spontaneous) Cerebrospinal Fluid Rhinorrhea From Cribriform Fistula Associated with Primary Empty Sella: Report of Two Cases and Literature Review Basit A. Syed, MS, MCh(SN), FRCSEd Cerebrospinal fluid (CSF) rhinorrhea is a distinct clinical condition requiring surgery to avoid potential complications, such as meningitis, abscess, and spontaneous pneumocephaly. The condition can be of traumatic or nontraumatic (spontaneous) etiology. The former is more common, and the latter has been considered rare since the first case reported by Miller in 1826. Nontraumatic rhinorrhea presents problems of diagnosis and choice of surgical operation. The precise demonstration of fistula is, therefore, of immense importance for a successful surgical outcome. Among the spontaneous group, CSF rhinorrhea occurring in association with primary empty sella (PES) is a recently recognized entity, and Ommaya et al. were the first to report this association. Most cases of CSF rhinorrhea in association with PES reported in the literature describe a sellar location of the fistulae, whereas an ethmoid location of the fistulae is rarely reported.

82. Endocrinología - El Síndrome De La Silla Vacía (Endocrinology - Empty S empty sella syndrome) http://www.mcghealth.org/Greystone/sadult/endocrin/sella.html

Contact Us Community Calendar Online Appointment Employee Intranet ... Printer Friendly Endocrinolog­a El S­ndrome de la Silla Vac­a ¿Qu© es el s­ndrome de la silla vac­a? El s­ndrome de la silla vac­a es comºn en mujeres con exceso de peso o que tienen presi³n sangu­nea alta. Se caracteriza por un agrandamiento de la estructura ³sea (silla turca) que aloja la gl¡ndula pituitaria en la base del cerebro; algunas veces el resultado de la enfermedad es la elevaci³n de la presi³n de los l­quidos dentro del cr¡neo. La gl¡ndula pituitaria generalmente es peque±a o de tama±o normal. ¿Cu¡les son los s­ ntomas del s­ndrome de la silla vac­a? Cada individuo puede experimentar los s­ntomas de una forma diferente. Adem¡s de la elevaci³n de la presi³n de los l­quidos dentro del cr¡neo, que ocurre aproximadamente en el 10 por ciento de los pacientes, otro s­ntoma es la secreci³n nasal cr³nica. ¿C³mo se diagnostica el s­ndrome de la silla vac­a? Adem¡s de la historia m©dica completa y el examen m©dico, los procedimientos para el diagn³stico del s­ndrome de la silla vac­a pueden incluir los siguientes: Rayos X del cr¡neo.

83. Arch Pediatr Adolesc Med -- Abstract: Empty Sella Syndrome Secondary To Intrasel empty sella syndrome secondary to intrasellar cyst in adolescence. S. Raiti, MJ Albrink, NK Maclaren, WM Chadduck, OF Gabriele and SM Chou http://archpedi.ama-assn.org/cgi/content/abstract/130/9/1009

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 130 No. 9, September 1976 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager Articles in PubMed by Raiti S Chou SM Contact me when this article is cited Empty sella syndrome secondary to intrasellar cyst in adolescence S. Raiti, M. J. Albrink, N. K. Maclaren, W. M. Chadduck, O. F. Gabriele and S. M. Chou A 15-year-old boy had growth failure and failure of sexual development. The probable onset was at age 10. Endocrine studies showed hypopituitarism with deficiency of growth hormone and follicle-stimulating hormone, an abnormal response to metyrapone, and deficiency of thyroid function. Luteinizing hormone level was in the low-normal range. Posterior pituitary function was

84. Thyrotropin And Prolactin Pituitary Reserve In The "empty Sella Syndrome" -- Rid Ten patients (8 women, 2 men) with the empty sella syndrome were studied to evaluate the pituitary reserve of human thyrotropin (hTSH) and prolactin http://jcem.endojournals.org/cgi/content/abstract/41/5/968

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS This Article Submit a related Letter to the Editor Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Ridgway, E. C. Articles by Maloof, F. ARTICLES Thyrotropin and prolactin pituitary reserve in the "empty sella syndrome" EC Ridgway, IA Kourides, B Kliman, T Bigos and F Maloof Ten patients (8 women, 2 men) with the "empty sella syndrome" were studied to evaluate the pituitary reserve of human thyrotropin (hTSH) and prolactin (hPRL). None of the patients had signs or symptoms of hypopituitarism or primary hypothyroidism. All patients had normal baseline thyroid function tests except for 2 patients with mild elevations in total triiodothyronine as measured by competitive protein displacement assay (T3D). Eight of ten patients had normal hTSH responses to thyrotropin releasing hormone (TRH)

85. Antipituitary Antibodies In Patients With The Primary Empty Sella Syndrome -- Ko to the development of pituitary atrophy and the primary empty sella syndrome, be clinically useful as a screening test for the empty sella syndrome. http://jcem.endojournals.org/cgi/content/abstract/67/4/633

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS This Article Submit a related Letter to the Editor Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Komatsu, M. Articles by Tanaka, K. ARTICLES Antipituitary antibodies in patients with the primary empty sella syndrome M Komatsu, T Kondo, K Yamauchi, N Yokokawa, K Ichikawa, M Ishihara, T Aizawa, T Yamada, Y Imai and K Tanaka Department of Gerontology, Shinshu University School of Medicine, Nagano-ken, Japan. The frequency of detection of serum antibodies against pituitary cells was determined in 32 patients with the primary empty sella syndrome. Antibodies reacting with corticotropin-secreting mouse AtT20 and PRL- secreting rat GH3 cells were found in 24 (75%) and 15 (47%), respectively, of the 32

86. Empty Sella Syndrome - SWMC Serving Vancouver Washington Portland Oregon empty sella syndrome Online Medical Encyclopedia courtesy of Southwest Washington Medical Center, a Top 100 Hosptital award winner locacted in Vancouver, http://www.swmedicalcenter.com/117960.cfm

@import url(default.css); Health Information Manager Back to Health Library Print This Page Email to a Friend The pituitary gland Empty sella syndrome Definition: Empty sella syndrome is the absence of the pituitary gland on radiological imaging of the sella turcica, a bony structure that normally partly surrounds the gland. Causes, incidence, and risk factors: The pituitary gland is a small gland located at the base of the brain. It makes several hormones that control the function of other glands in the body, including the thyroid, the adrenal glands, and the ovaries or testes. The pituitary gland is partly surrounded by a bony structure called the sella turcica ("Turkish saddle"). When the pituitary gland is not visible on CT or MRI scans of the sella turcica, the condition is referred to as empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten out along the walls of the sella. When the sella is empty because the pituitary gland has regressed following an injury such as head trauma or an event such as surgery or radiation therapy, the condition is called secondary empty sella syndrome. Primary empty sella syndrome is most often an incidental finding during radiological imaging of the brain . Pituitary function is usually normal, and patients do not have any symptoms. The hormone prolactin is mildly elevated in 10% to 15 % of patients, and the elevated prolactin may interfere with normal function of the testes or ovaries.

87. MeSH empty sella syndromes; Empty Sella Turcica Syndrome; empty sella syndrome, Primary; Primary empty sella syndrome; empty sella syndrome, Secondary http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=mesh&list_uids=680

88. News - Case Of Empty Sella Syndrome Syndrome Mistakenly Diagnosed As Syndrome Of Case of empty sella syndrome Syndrome Mistakenly Diagnosed as Syndrome of Inappropriate Antidiuretic. http://www.docguide.com/news/content.nsf/news/8525697700573E188525700D0052680E

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89. P\S\L - News Case Of Empty Sella Syndrome Syndrome Mistakenly Few cases of empty sella syndrome mistakenly diagnosed as syndrome of If an endocrinologist had not caught empty sella syndrome in this patient, http://main.pslgroup.com/news/content.nsf/MedicalNews/8525697700573E188525700D00

90. Does Pseudotumor Cerebri Cause The Empty Sella Syndrome? -- Foley And Posner 25 Eight patients had both the primary empty sella syndrome, diagnosed by the finding of an airfilled sella turcica at pneumoencephalography, http://www.neurology.org/cgi/content/abstract/25/6/565

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Foley, K. M. Articles by Posner, J. B. ARTICLES Does pseudotumor cerebri cause the empty sella syndrome? KM Foley and JB Posner Eight patients had both the "primary empty sella syndrome," diagnosed by the finding of an air-filled sella turcica at pneumoencephalography, and pseudotumor cerebri, diagnosed by the finding of an elevated cerebrospinal fluid pressure in the presence of normal ventricular size and position on pneumonencephalography. All eight patients were obese women, and six were hypertensive. Six complained of headaches and menstrual irregularities, and

91. The Empty Sella Syndrome -- Sachdev Et Al. 52 (613): 703 -- Postgraduate Medical The empty sella syndrome. Y Sachdev, DC Evered, A Appleby and R Hall. The empty sella syndrome (ESS) presents a varied clinical and radiographic picture. http://pmj.bmjjournals.com/cgi/content/abstract/52/613/703

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS Author Keyword(s) Vol Page [Advanced] This Article Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Sachdev, Y. Articles by Hall, R. Postgraduate Medical Journal, 1976, Vol 52, 703-705 ARTICLES The empty sella syndrome Y Sachdev, DC Evered, A Appleby and R Hall The empty sella syndrome (ESS) presents a varied clinical and radiographic picture. It may remain asymptomatic or may stimulate an intrasellar growth thereby causing diagnostic and therapeutic problems. An air encephalogram (AEG) is required for diagnosis. The purpose of this paper is to review the clinical and radiological features of the ESS and to discuss the pathogenetic mechanisms involved.

92. Dynamic Roentgenographic Changes In The Empty Sella Syndrome -- Grossman 116 (2) Dynamic roentgenographic changes in the empty sella syndrome. CB Grossman. Two cases of empty sella syndrome are presented. Progressive sellar enlargement http://radiology.rsnajnls.org/cgi/content/abstract/116/2/341

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Grossman, C. B. ARTICLES Dynamic roentgenographic changes in the empty sella syndrome CB Grossman Two cases of empty sella syndrome are presented. Progressive sellar enlargement was documented together with evidence of increased intracranial pressure. One patient exhibited de novo development of an empty sella turcica. HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE

93. Endotext.com - Neuroendocrinology, Hypothalamus, And Pituitary, Pituitary – Hyp Arachnoid cysts 1.6. empty sella syndrome 1.6.1. Primary empty sella A primary empty sella syndrome is often discovered accidentally since it is usually http://www.endotext.org/neuroendo/neuroendo11b/neuroendo11b.htm

PITUITARY - HYPOTHALAMIC TUMOR SYNDROMES: ADULTS Chapter 11b - Klaus von Werder, MD, FRCP August 22, 2002 Contents Contributors Search Space Occupying Lesions in the hypothalamic/pituitary region include tumors derived from endocrine or neural tissues, metastatic tumors, chronic inflammatory processes, cystic lesions or vascular aneurysms (Table 1). These lesions may be clinically silent, i. e. do not cause any endocrine, visual or other neurological disturbances, though they often lead to pituitary enlargement and are therefore discovered accidentally when skull X-ray, cranial CT, or MRI is performed for other reasons. These tumors are called pituitary incidentalomas. Management, i. e. therapy and follow up depends on the nature and position of the lesion (1). More frequently, a variety of endocrine, ophthalmological, or neurological symptoms lead the clinician to the diagnosis of a space occupying lesion within the sellar or supra-sellar region, i. e. a pituitary tumor with intra-, supra-, and para-sellar extension or a primary hypothalamic tumor which also may extend into the sellar cavity (Fig. 1). Figure 1.

94. Endotext.com - Neuroendocrinology, Hypothalamus, And Pituitary - Radiotherapy Fo However an empty sella syndrome has been described in patients who suffer from a combination of headache, pituitary dysfunction and visual disturbance http://www.endotext.org/neuroendo/neuroendo4/neuroendo4_3.htm

Go Back OPTIC NERVE GLIOMAS Optic nerve and optic chiasm gliomas occur in two varieties: a non-invasive, indolent neoplasm that is typically found in children and an invasive neoplasm that is found in adults. The former is frequently associated with neurofibromatosis type I. Both forms of the tumor produce a well-defined expansion of the optic chiasm and/or the optic nerves. Optic nerve and chiasmal gliomas in children usually have homogeneous signal intensity iso-intense or hyper-intense to gray matter with no contrast enhancement. The chiasmal gliomas of adults have greater inhomogeneity and often have contrast enhancement. These often extend into the hypothalamus or involve the hypothalamus primarily [FIG 22]. Figure 22. Suprasellar astrocytoma. The high water content of this tumor causes low T1 signal (A) and high signal on T2 (B) and FLAIR images (C) Dense uniform enhancement is demonstrated following contrast administration (D). SARCOIDOSIS Sarcoidosis may involve the leptomeninges of the brain, producing granulomas on the pituitary stalk, optic chiasm or lesions of the cerebral parenchyma. The granulomas demonstrate marked contrast enhancement. One of the most typical appearances is a thickened contrast enhancing infundibulum. Lymphoma, metastatic carcinoma and Langherhan's cell histiocytosis X may produce this finding as well [FIG 23].

95. ► Empty-sella Syndrome A medical encycopedia article on the topic empty-sella syndrome. http://www.umm.edu/ency/article/000349.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Disease Nutrition Surgery Symptoms Injury ... Encyclopedia (English) Toggle English Spanish Empty-sella syndrome Overview Symptoms Treatment Prevention Definition: Absence of the pituitary gland on radiological imaging of the sella turcica, a bony structure that partly surrounds the gland. Causes, incidence, and risk factors: The pituitary gland is a small, oval gland at the base of the brain. It makes several hormones that control the function of other glands in the body including the thyroid gland, adrenal glands, and gonads (ovaries or testes). The pituitary gland is partly surrounded by a bony structure called the sella turcica (Turkish saddle). When the pituitary gland is not visible on CT or MRI scans of the sella turcica, the condition is referred to as the empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten out along the walls of the sella. When the sella is empty because the pituitary gland has regressed following an injury (e.g., surgery, head trauma, radiation therapy), the condition is called secondary empty sella syndrome. Primary empty sella syndrome is most often an incidental finding on radiological imaging of the brain. Pituitary function is usually normal, and patients do not have any symptoms. The hormone prolactin is mildly elevated in 10-15 % of patients, and the elevated prolactin may interfere with normal function of the testes or ovaries. Medications that suppress prolactin production (e.g., bromocriptine) are effective in correcting the problem.

96. Empty Sella Presenting As A Syndrome Of Inappropriate Antidiuretic Hormone Secre empty sella presenting as a syndrome of inappropriate antidiuretic hormone secretion MRI scan of the pituitary gland showed an empty sella . http://www.endocrine-abstracts.org/ea/0005/ea0005p65.htm

Endocrine Abstracts previous abstract next abstract Abstract Empty sella presenting as a syndrome of inappropriate antidiuretic hormone secretion AFA Helmy Department of Diabetes and Endocrinology, Basildon Hospital, Essex, UK. An 85 year old woman presented with generalised fatigue.Clinical examination was unremarkable but her biochemistry showed low sodium level of 112 millimoles per litre ( NR : 135-145 ). Investigations were suggestive of Syndrome of Inappropriate Antidiuretic Hormone Secretion ( SIADH ) with low serum osmolality , high urine osmolality and high urinary sodium . Further investigations were normal including renal function , short synacthen test , chest x-ray and CT scan of the head . However the rest of her hormonal profile showed low TSH , low free T4 , low free T3 as well as low FSH and low LH levels but normal prolactin. MRI scan of the pituitary gland showed an 'Empty Sella ' . She did have a poor response to fluid restriction alone but started to respond gradually when Demeclocycline was added with a small dose of Thyroxine . Discussion : An ' Empty Sella ' is sometimes reported on pituitary imaging. This is sometimes due to a defect in the diaphragma and extension of the subarachnoid space ( cisternal herniation ) or may follow spontaneous infarction of a pituitary tumour. All or most of the sella tursica is devoid of apparent pituitary tissue which is eccentrically placed and flattened against the floor or roof of the fossa . Pituitary function is usually normal . However , Empty Sella remains one of the causes of Hypopituitarism .

97. Arch Pediatr Adolesc Med -- Abstract: Empty-sella Syndrome. Occurrence In Childh emptysella syndrome. Occurrence in childhood. IA Wilkinson, SC Duck, Primary empty-sella syndrome has been rarely reported in childhood. http://archpedi.ama-assn.org/cgi/content/abstract/136/3/245

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 136 No. 3, March 1982 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager Articles in PubMed by Wilkinson IA Daniels DL Contact me when this article is cited Empty-sella syndrome. Occurrence in childhood I. A. Wilkinson, S. C. Duck, W. E. Gager and D. L. Daniels Primary empty-sella syndrome has been rarely reported in childhood. Substantial visual disturbance was accompanied by minimal endocrine dysfunction in an 8-year-old girl whose only other complaint was headache. This syndrome in children is associated with more dramatic signs and symptoms than have been reported for adults and may be associated with progressive destruction of pituitary reserve.

98. Entrez PubMed Bartter s syndrome is characterized by hypochloremia, hypokalemia, metabolic alkalosis associated wi http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

99. Arch Otolaryngol Head Neck Surg -- Abstract: CSF Rhinorrhea Associated With The CSF rhinorrhea associated with the emptysella syndrome empty-sella syndrome should be considered a diagnostic possibility in patients with nontraumatic http://archotol.ama-assn.org/cgi/content/abstract/106/5/302

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 106 No. 5, May 1980 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager Articles in PubMed by Gray WC Leveque H Contact me when this article is cited CSF rhinorrhea associated with the empty-sella syndrome W. C. Gray, M. Salcman, K. Rao and H. Leveque The empty-sella syndrome consists of the abnormal extension into the sella turcica of an arachnoid diverticulum filled with CSF, which displaces and compresses the pituitary gland. Such a diverticulum can erode through the sellar floor and lead to CSF rhinorrhea through the sphenoidal sinus. Empty-sella syndrome should be considered a diagnostic possibility in patients with nontraumatic CSF rhinorrhea. Diagnosis and treatment are best accomplished with a team approach involving the otolaryngologist

100. Endocrinología - El Síndrome De La Silla Vacía (Endocrinology - Empty S Translate this page El Síndrome de la Silla Vacía. ¿Qué es el síndrome de la silla vacía? El síndrome de la silla vacía es común en mujeres con exceso de peso o que tienen http://www.mcghealth.org/printer/internet/Greystone/sadult/endocrin/sella.html

MCG Health System Endocrinolog­a El S­ndrome de la Silla Vac­a ¿Qu© es el s­ndrome de la silla vac­a? El s­ndrome de la silla vac­a es comºn en mujeres con exceso de peso o que tienen presi³n sangu­nea alta. Se caracteriza por un agrandamiento de la estructura ³sea (silla turca) que aloja la gl¡ndula pituitaria en la base del cerebro; algunas veces el resultado de la enfermedad es la elevaci³n de la presi³n de los l­quidos dentro del cr¡neo. La gl¡ndula pituitaria generalmente es peque±a o de tama±o normal. ¿Cu¡les son los s­ ntomas del s­ndrome de la silla vac­a? Cada individuo puede experimentar los s­ntomas de una forma diferente. Adem¡s de la elevaci³n de la presi³n de los l­quidos dentro del cr¡neo, que ocurre aproximadamente en el 10 por ciento de los pacientes, otro s­ntoma es la secreci³n nasal cr³nica. ¿C³mo se diagnostica el s­ndrome de la silla vac­a? Adem¡s de la historia m©dica completa y el examen m©dico, los procedimientos para el diagn³stico del s­ndrome de la silla vac­a pueden incluir los siguientes: Rayos X del cr¡neo.

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