1. Engle Laboratory Localization of a gene for duane retraction syndrome to chromosome 2q31. Kirkham, T. Duane s retraction syndrome and cleft palate. http://www.childrenshospital.org/cfapps/research/data_admin/Site339/mainpageS339

Children's Hospital Research Children's Hospital Labs Engle Laboratory Engle Lab Home Page Eye disorders studied Eye muscle anatomy CFEOM ... Congenital ptosis Duane syndrome Horizontal gaze palsy with progressive scoliosis Marcus Gunn syndrome Genes identified Research Participation ... Contact Us Duane syndrome Duane syndrome with radial ray anomalies DURS2 locus DURS1 locus Research: Duane syndrome Duane syndrome (DS) is an eye movement disorder present at birth (congenital) characterized by a limited ability to move an eye inward towards the nose (adduction), outward towards the ear (abduction), or in both directions. In addition, when the affected eye(s) move inward towards the nose, the eyeball retracts (pulls in) and the eye opening (palpebral fissure) narrows. In some cases when the eye attempts to look inward, it moves upwards (upshoot) or downwards (downshoot). Similar to CFEOM, Duane syndrome falls under the larger heading of strabismus (misalignment of the eyes) under the subclassification of incomitant strabimsus (misalignment of the eyes which varies with gaze directions) and subheading of extraocular muscle fibrosis syndromes (conditions associated with restriction of both active and passive movement of the eyeball). Although "muscle fibrosis" suggests that syndromes under this heading are primary disorders of muscle, evidence suggests that DS (and other Congenital Cranial Dysinnervation Disorders-CCDD's) may actually be primary disorders of nerve innervation

2. HOME: Internet Ophthalmology A description of DRS, with clinical manifestations, pathogenesis and treatment. From University at Buffalo School of Medicine and Biomedical Sciences. http://www.smbs.buffalo.edu/oph/ped/duanes.htm

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3. HONselect - Duane Retraction Syndrome Ocular Retraction Syndrome - duane retraction syndrome, Type 1 - duane retraction syndrome, Type 2 - duane retraction syndrome, Type 3 - Duane http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. DUANE RETRACTION SYNDROME Contact A Family - For Families With printer friendly duane retraction syndrome search this site home how we can help medical information index of conditions http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Duane Retraction Syndrome - Ocular Retraction Syndrome - Information Page With H A syndrome characterized by marked limitation of abduction of the eye, variable http://www.hon.ch/HONselect/RareDiseases/EN/C10.292.562.250.html

InitBulle("navy","#F8F8F8","#000066",1); HONcode sites All Web sites HONselect News ... Images HONselect Search English French German Spanish Portuguese the word the part of word in MeSH term in MeSH term and description Information on "Duane Retraction Syndrome": Medical hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Hierarchy English French German Spanish Portuguese Duane Retraction Syndrome Definition: A syndrome characterized by marked limitation of abduction of the eye, variable limitation of adduction and retraction of the globe, and narrowing of the palpebral fissure on attempted adduction. The condition is caused by aberrant innervation of the lateral rectus by fibers of the oculomotor nerve. There are three subtypes: type 1 (associated with loss of abduction), type 2 (associated with loss of adduction), and type 3 (loss of abduction and adduction). Two loci for Duane retraction syndrome have been located, one at chromosome 8q13 (DURS1) and another at chromosome 2q31(DURS2). It is usually caused by congenital hypoplasia of the abducens nerve or nucleus, but may rarely represent an acquired syndrome. (Adams et al., Principles of Neurology, 6th ed, p271; Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p691) Synonym(s): Ocular Retraction Syndrome / Duane Retraction Syndrome, Type 1 / Duane Retraction Syndrome, Type 2 / Duane Retraction Syndrome, Type 3 /

6. OSL Medial Rectus Re-recession For Unacceptable Head-Turn And Medial Rectus Rerecession for Unacceptable Head-Turn and Esotropia in Duane's Retraction Syndrome. Ben Zion Biedner, MD http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. HONselect - Duane Retraction Syndrome Translate this page English, duane retraction syndrome, - Ocular Retraction Syndrome - Duane RetractionSyndrome, Type 1 - duane retraction syndrome, Type 2 http://www.hon.ch/HONselect/RareDiseases/C10.292.562.250.html

List of rare diseases: English Deutsch Language: MeSH term: Accepted terms: English: Duane Retraction Syndrome - Ocular Retraction Syndrome - Duane Retraction Syndrome, Type 1 - Duane Retraction Syndrome, Type 2 - Duane Retraction Syndrome, Type 3 - Duane Syndrome - Duane's Syndrome Français: Syndrome de rétraction du globe oculaire de Duane - Duane rétraction, syndrome - Syndrome de rétraction - Syndrome de Duane - Syndrome de Stilling-Türk-Duane - Syndrome de rétraction de Duane de type II - Syndrome de rétraction de Duane de type 2 Deutsch: Duane-Retraktionssyndrom - Retractio bulbi - Okuläres Retraktionssyndrom - Stilling-Türk-Duane-Syndrom Español: Síndrome de Retracción de Duane - Síndrome de Retracción Ocular Português: Síndrome da Retração Ocular - Síndrome de Retração Ocular HONselect ressources Definition: Yes Articles: Yes Images: No News: No Conferences: No Clinical trials: No Web sites: English Yes Français Yes Deutsch No Español No Português No Home About us Site map Search ... Contact http://www.hon.ch/HONselect/RareDiseases/C10.292.562.250.html Last modified: Wed May 18 2005

8. Handbook Of Ocular Disease Management - Duane's Retraction Syndrome Signs and symptoms Duane's retraction syndrome (DRS) is a congenital disorder of ocular motility characterized by lim ited abduction http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. EMedicine - Duane Syndrome : Article By Arun Verma, MD Duane Syndrome duane retraction syndrome (DRS) was first described in the laterpart of the 19th century by Sinclair (1895), Bahr (1896), Stilling (1887), http://www.emedicine.com/oph/topic326.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Ophthalmology Extraocular Muscles Duane Syndrome Last Updated: June 9, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: Duane's syndrome, Duane retraction syndrome, DRS, congenital retraction syndrome, Stilling-Turk-Duane retraction syndrome, congenital ocular motility disorder AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Arun Verma, MD , Senior Consultant, Department of Ophthalmology, Daljit Singh Eye Hospital, Amritsar, India Editor(s): Gerhard W Cibis, MD , Director of Pediatric Ophthalmology Service, Clinical Professor, Department of Ophthalmology, University of Kansas; Director, Clinical Professor, Department of Ophthalmology, Children's Mercy Hospital, University of Missouri at Kansas City; Donald S Fong, MD, MPH

10. Stilling-T Rk-Duane Syndrome (www.whonamedit.com) deficiency, eye retraction syndrome, ocular retraction syndrome, retractio bulbi, retraction syndrome. Associated persons Alexander Duane http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. EMedicine - Globe Retraction : Article Excerpt By: Michael T Yen, MD of the horizontal rectus muscles such as in duane retraction syndrome.Patients with Duane syndrome have strabismus, upshooting or downshooting eye http://www.emedicine.com/oph/byname/globe-retraction.htm

(advertisement) Excerpt from Globe Retraction Synonyms, Key Words, and Related Terms: enophthalmos, diplopia, orbital blowout fracture, orbital fracture, orbital trauma, ocular trauma, eye trauma, eye injury, sports injury, retracted globe, Duane retraction syndrome, Duane syndrome, amblyopia, orbital tumor, orbital metastasis, breast cancer, breast carcinoma, lung cancer, lung carcinoma, prostate cancer, prostate carcinoma, metastatic carcinoma Please click here to view the full topic text: Globe Retraction Background: Globe retraction occurs when globe is displaced deeper within the orbit from its normal position. It may occur from active co-contraction of the horizontal rectus muscles such as in Duane retraction syndrome. Patients with Duane syndrome have strabismus, upshooting or downshooting eye movements, and narrowing of palpebral fissure and retraction of globe on adduction. Enlargement of orbital cavity after orbital blowout fractures also may cause the globe to be retracted. It may be due to prolapse of orbital contents into adjacent sinuses, atrophy of orbital fat, or contracture of necrotic extraocular muscles entrapped within the fracture. Globe retraction also can be seen in metastatic scirrhous breast carcinoma from cicatrization of orbital tissue. Although less common, some cases of sclerosing orbital pseudotumor have been reported to cause globe retraction. A thorough history and examination are required to determine appropriate management for patients with globe retraction.

12. Arch Ophthalmol Abstract Infrared Oculography Of Duane's Infrared oculography of Duane's retraction syndrome (type 1) http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. DUANE RETRACTION SYNDROME: Contact A Family - For Families With Disabled Childre Contact a Family is a UK charity for families with disabled children. We offerinformation on specific conditions and rare disorders. http://www.cafamily.org.uk/Direct/d35.html

printer friendly DUANE RETRACTION SYNDROME home how we can help medical information index of conditions ... how you can help Did you find this page helpful? yes no Contact a Family has hosted two telephone conferences for families of children with Duane syndrome. A follow up conference call is planned for Spring 2005. If you are a UK based family and would like to take part in this please contact the Freephone Helpline for details. Duane Retraction syndrome: Duane syndrome; DRS Duane Retraction syndrome is a congenital disorder of ocular movements which was first described in 1905. There are three types of DRS that share common features. The condition may affect one or both eyes. DRS more commonly affects the left eye and is more common in girls. The reasons for this are not yet known. In DRS there is an abnormality of horizontal eye movements resulting in restriction of the affected eye from turning outwards or inwards or in both directions. As the eye is turned in toward the nose (called adduction) the eyelids narrow as the eye is apparently drawn back (retracted). As the affected eye is turned outwards (abducted), the eye lids widen. There may be associated vertical eye movement changes causing an up shoot or down shoot. Individuals who are affected with DRS may also have a squint (strabismus) when they look straight ahead. It is possible to have good vision in each eye with stereo vision. However, in order to maintain stereo vision, individuals with DRS may adopt a face turn.

14. Health Conditions Diseases Neurological Disorders Ocular Motility IndiaPress Directory powered by DMOZ of Health Conditions Diseases Neurological Disorders Ocular Motility Disorders duane retraction syndrome http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Index D: Contact A Family - For Families With Disabled Children: Information On DRS see duane retraction syndrome Dancing Eye syndrome DandyWalker Cysts seeDandy-Walker Down syndrome with Heart Defect duane retraction syndrome http://www.cafamily.org.uk/Idx/d.html

printer friendly home how we can help medical information ... how you can help Please use the index below to access the condition you require information on. It may take longer to find what you are looking for this way compared with our "search this site" facility in the navigator on the left but we try to point you in the most appropriate direction using this index and therefore the results should be better. For speed, this index has been split into separate alphabetical files: numbers 0-9 A B C ... Z Contact a Family also has information on many other specific conditions and rare disorders. If you cannot find the information you require in The Contact a Family Directory Online , you may wish to use our Contact a Family Helpline service. D+HUS see Haemolytic Uraemic syndrome DAF syndrome see Niemann-Pick disease DAMP see Attention Deficit Hyperactivity Disorder DDH see Congenital Dislocation and Developmental Dysplasia of the Hip DGS see 22q11 Deletion syndromes DHPA see DHPD see DRS see Duane Retraction syndrome Dancing Eye syndrome Dandy-Walker Cysts see Dandy-Walker syndrome Dandy-Walker syndrome Darier disease De Morsiers syndrome see Septo-Optic Dysplasia Deafblindness Deafness Deafness with goiter see Pendred syndrome Deficiency of HLA Expression see Primary Immunodeficiencies Degos disease Dejerine-Sottas disease see Muscular Dystrophy and neuromuscular disorders Dementia, Hereditary Multi-infarct Type see

16. Duane Retraction SyndromeDirectory Health Conditions And duane retraction syndrome Directory Health Conditions and Diseases Neurological Disorders Ocular Motility Disorders duane retraction syndrome A http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Duane Retraction Syndrome Definition - Medical Dictionary Definitions Of Popular Online Medical Dictionary and glossary with medical definitions. http://www.medterms.com/script/main/art.asp?articlekey=26329

18. Journal Of Pediatric Ophthalmology And Strabismus Management of duane retraction syndrome. This continuing medical education activityis sponsored by SLACK Incorporated. Journal of Pediatric Ophthalmology http://www.journalofpediatricophthalmology.com/showAbst.asp?thing=9688

19. Journal Of Pediatric Ophthalmology And Strabismus Association of duane retraction syndrome and Brown Syndrome. Journal of PediatricOphthalmology and Strabismus Vol. 42 No. 4 July/August 2005 http://www.journalofpediatricophthalmology.com/showAbst.asp?thing=10930

20. HighWire -- Browse Journals - Duane Retraction Syndrome Browse Journals publishing on duane retraction syndrome, (return to Topic Listpage) Alphabet, , Frequency of articles in duane retraction syndrome http://highwire.stanford.edu/lists/topic_dir/608683/608684/617096/617097/617202/

ANNOUNCEMENT: CHECK OUT THE PREVIEW RELEASE OF OUR NEW WEB SITE! My Favorite Journals ( HW-hosted journals HW-hosted Medline Author: Keyword(s): Year: Vol: Page: Home Adv. Search For Institutions For Publishers ... Sign in or register for access to all HighWire Press customization features Browse Journals publishing on Duane Retraction Syndrome: (return to Topic List page) Duane Retraction Syndrome Sort by: Alphabet Frequency of articles in Duane Retraction Syndrome Focus of journal on Duane Retraction Syndrome What's this? Journals focusing on Duane Retraction Syndrome (in order by highest focus) Neurology info free ISSUES Home ... Ocular Motility Disorders Duane Retraction Syndrome Home Adv. Search For Institutions For Publishers ... partners/suppliers

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