81. Neuropathic Pain And Neuropathy Neuropathy and diabetic Neuropathy Life Extension Foundation; Pain (Chronic) -Life Extension Foundation; The pain is severe; my feet feel like they are http://qualitycounts.com/fpneuropathic_pain.html

This site is supported by commissions from my affiliates. If you could, please place orders directly via the links on my site. Quality Counts .com Comprehensive Anti-aging Research iHerb 7.5% discount code "qc"/Free shipping on orders over $20 Home iHerb Vitacost ... Drug Databases Longevity Affiliates: Complete Shopping Directory iHerb 7.5% discount code"qc" Life Extension Buyers Club Int. Anti-aging Systems ... Health Conditions Neuropathic Pain/Neuropathy Related Topics: Pain Popular Medications: Neurontin Effexor Lamictal (lamotrigine) Topamax® (topiramate) Popular Supplements: benfotiamine alpha lipoic acid D-phenylalanine enzymes Alternative News: Neuropathy and Diabetic Neuropathy - Life Extension Foundation Pain (Chronic) - Life Extension Foundation The pain is severe; my feet feel like they are on fire. Do you have any recommendations? - Dr. Murray Treatment for diabetic mononeuropathy with alpha-lipoic acid - Int J Clin Pract. 2005 Jun;59(6):645-50 - "alpha-lipoic acid appears to be an effective drug in the treatment for not only peripheral and autonomic diabetic neuropathy, but also diabetic mononeuropathy of the cranial nerves leading to full recovery of the patients" - See iHerb alpha-lipoic acid products (7.5% discount code "qc").

82. Virtual Hospital: University Of Iowa Family Practice Handbook, Fourth Edition: N diabetic neuropathy. This is the most common cause of diffuse polyneuropathy.It arises in one half of all diabetics, and the neuropathy is primarily axonal http://www.vh.org/adult/provider/familymedicine/FPHandbook/Chapter09/10-9.html

University of Iowa Family Practice Handbook, Fourth Edition, Chapter 9 Neurology: Neuropathy Coleman O. Martin, MD Department of Neurology University of Iowa College of Medicine Peer Review Status: Externally Peer Reviewed by Mosby Overview Neuropathy Classification Anatomic classification Mononeuropathy . Involvement of a single nerve (e.g., carpal tunnel syndrome, meralgia paresthetica). Polyneuropathy . Diffuse involvement of the peripheral nerves (e.g., diabetic neuropathy). Mononeuritis multiplex . Seemingly random involvement of multiple isolated nerves. Can occur in vasculitis, porphyria, diabetes, HIV, and others. Cellular classification Axonal neuropathy . Loss of function from loss of nerve cells. Typically affects longest nerves first with patients describing loss of sensation or paresthesias of the feet. Axonal neuropathy is usually symmetric, although it may be asymmetric early in the course. Weakness occurs late and tends to involve the most distal muscles. Demyelinating neuropathy . Damage to the Schwann cells leads to impairment of nerve conduction. Weakness tends to involve both proximal and distal muscles. Time course Acute neuropathy . Sudden onset of dysfunction from an injury or immunologic attack. Chronic neuropathy . Usually insidious onset with slow progression from low-level ongoing nerve injury. Diagnosis Careful history

83. New Study Shows Effexor(R) XR Reduces Pain Associated With Diabetic Neuropathy As diabetic neuropathy progresses over time, the pain caused by nerve damage may About Diabetes and diabetic Neuropathy Diabetes affects 15.7 million http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/06-12-200

84. Small Fiber Neuropathy In Diabetes: Clinical Consequence And Assessment -- Quatt diabetic autonomic neuropathy and the heart. Diabetes Res Clin Pract 1996;303136 The pathology of human diabetic neuropathy. Diabetes 1997;46S50-S53. http://ijl.sagepub.com/cgi/content/refs/3/1/16

JOURNAL HOME HELP CONTACT US SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: The International Journal of Lower Extremity Wounds, Vol. 3, No. 1, 16-21 (2004) DOI: 10.1177/1534734603262483 This Article Abstract Full Text (PDF) References ... Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager ... Reprints and Permissions PubMed PubMed Citation Articles by Quattrini, C. Articles by Malik, R. A. Small Fiber Neuropathy in Diabetes: Clinical Consequence and Assessment C. Quattrini Department of Medicine, Manchester Royal Infirmary, UK, LMAG School of Medicine, Dentistry, Nursing and Pharmacy, University of Manchester, Manchester, UK M. Jeziorska LMAG School of Medicine, Dentistry, Nursing and Pharmacy, University of Manchester, Manchester, UK R. A. Malik Department of Medicine, Manchester Royal Infirmary, UK, Recent findings have shed new light on the role of peripheral nerves in the skin and have established a modern concept of cutaneous neurobiology. There is bidirectional rather than unidirectional

85. UMHS Press Release: U-M Neuropathy Center Opens diabetic peripheral neuropathy, which occurs when high blood sugar and the immune For more information on diabetic neuropathy research at the UM visit http://www.med.umich.edu/opm/newspage/2005/neuropathy.htm

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86. Neuropathy Neuropathy Updated December 23, 2004 diabetic Neuropathy What You Can DoAbout It American Academy of Family Physicians (also in Spanish) http://www.noah-health.org/en/endocrine/diabetes/concerns/neuropathy.html

Skip navigation About NOAH Help English Spanish Both Advanced NOAH Endocrine Disorders Change text size: Neuropathy Updated: December 23, 2004 Autonomic Neuropathy Mayo Clinic Diabetic Neuropathy American Geriatric Society Diabetic Neuropathy: What You Can Do About It American Academy of Family Physicians (also in Spanish Diabetes Neuropathies: The Nerve Damage of Diabetes National Institute of Diabetes and Digestive and Kidney Diseases Neuropathy Joslin Diabetes Center Neuropathy JAMA Patient Page Neuropathy and Nerve Damage American Diabetes Association NINDS Diabetic Neuropathy Information Page National Institute of Neurological Disorders and Stroke Peripheral Neuropathy Mayo Clinic Prevent Diabetes Problems: Keep Your Nervous System Healthy National Institute of Diabetes and Digestive and Kidney Diseases (also in Spanish Information Resources Peripheral Neuropathy Webforum Harvard Univ Researched by NOAH Contributing Editor: NOAH Team NOAH Endocrine Disorders Diabetes Complications and Concerns > Neuropathy Health Topics Index A to Z Page of the Month Advanced Search ... Feedback

87. Journal Of Clinical Neuromuscular Disease - UserLogin The authors have yet to define what diabetic neuropathy is or what diabetic Astonishingly, there is a section entitled Central diabetic neuropathy. http://www.jcnmd.com/pt/re/jclnnmd/fulltext.00131402-200406000-00009.htm

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88. Diabetes Insight - Neuropathy - Diabetic Complications Diabetes Insight and Support has been set up to provide support, information anda discussion forum for people and families living with diabetes in the UK, http://www.diabetes-insight.info/lwd/complications/neurpthy.asp

Diabetes and Neuropathy. Nervous System Impairment (Neuropathy) Diabetic Neuropathy can affect virtually every part of the body. Diabetic nerve damage eventually affects some 65 percent of people with diabetes. As with other diabetes complications, poor blood glucose control lies at the root of neuropathy. As average glucose level increases, so does risk of neuropathy. However, scientists still are not sure why high blood glucose levels should interfere with the nervous system. Oddly, neuropathy does not affect the brain or spinal nerves. But it can damage the rest of the nervous system. Symptoms may include: a loss of bowel or bladder control, problems with digestion, muscle weakness, sex problems, pain or a pins-and-needles feeling in the hands or feet, or a loss of pain sensation in the extremities, which may contribute to such problems as foot ulcers. The symptoms of neuropathy also depend on which nerves and what part of the body is affected. Neuropathy may be diffuse, affecting many parts of the body, or focal, affecting a single, specific nerve and part of the body. The two categories of diffuse neuropathy are peripheral neuropathy affecting the feet and hands and autonomic neuropathy affecting the internal organs.

89. Entrez PubMed The mechanisms underlying painful diabetic neuropathy remain poorly understood . These results suggest that painful diabetic neuropathy is associated http://www.molecularpain.com/pubmed/15513920

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90. Neuropathological Alterations In Diabetic Truncal Neuropathy: Evaluation By Skin diabetic truncal neuropathy is one of the many peripheral neuropathic diabetic truncal neuropathy usually affects the middle and lower thoracic segments http://www.jnnp.com/cgi/content/full/65/5/762

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91. Florida State University College Of Medicine Digital Library diabetic Neuropathy (Keyword search) List of document Additional diabeticNeuropathy resources (These sites have not been reviewed. http://fsumed-dl.slis.ua.edu/clinical/endocrinology/diabetes/diabetes-complicati

Clinical Resources by Topic: Endocrinology Diabetic Neuropathy Clinical Resources Emergency Geriatrics Pathology Physical/Rehabilitation ... Miscellaneous Resources See also: General Endocrinology Clinical Resources Diabetes Prevention and Screening Resources Diabetic Neuropathy Patient/Family Resources Harrison's Principles of Internal Medicine 16th Ed.-2005: Table of contents Medical Library subscription INFO Chapter 363. Approach to the Patient with Peripheral Neuropathy: Table of contents Introduction: Access document Polyneuropathy: Access document Mononeuropathy Multiplex (Multifocal Neuropathy): Access document Assessment and Diagnosis of Polyneuropathy and Mononeuropathy Multiplex: Access document Special Categories of Neuropathy: Access document Special Neuropathic Presentations: Access document Recovery from Neuropathy: Access document Further Reading: Access document Chapter 323. Diabetes Mellitus: Access document Chronic Complications of DM: Access document Chapter 355. Trigeminal Neuralgia, Bell's Palsy, and Other Cranial Nerve Disorders: Table of contents Introduction: Access document Multiple Cranial Nerve Palsies: Access document Acknowledgement: Access document Further Reading: Access document Chapter 354. Disorders of the Autonomic Nervous System:

92. (ATN) Neuropathy Nutrient Therapies diabetic neuropathy is known to be associated with a reduction in myoinositollevels in Treatment of diabetic neuropathy with gamma-linolenic acid. http://www.aegis.com/pubs/atn/1996/ATN25009.html

ATN) Neuropathy: Nutrient Therapies AIDS TREATMENT NEWS No. 250 - July 5, 1996 Lark Lands Dr. Lands also has had lifelong diabetes, and is an expert on diabetic neuropathy, which has been much better researched than neuropathy caused by HIV. She believes that some (not all) kinds of HIV-related neuropathy may be similar to the diabetic condition, and may respond to some of the same treatments. AIDS TREATMENT NEWS asked Dr. Lands if we could interview her on what has been learned about treating diabetic neuropathy, and how that might apply to HIV. It turned out to be more practical to publish a section of Dr. Lands' new book than to conduct a separate interview. Readers should know that Dr. Lands emphasizes an integrated program of HIV disease management including antivirals and other mainstream medical treatments, nutritional approaches, and other kinds of therapy rather than using nutrition to treat only a specific symptom. Also, her book includes a detailed section on different kinds of HIV neuropathies. Other sections focus in detail on specific nutrients and other therapies, providing much information not included here. Unfortunately the book is not yet available. But readers should know about potential therapies which, although not conclusively proven and not officially approved, are supported by research, and have appeared to be helpful for many people. Patients should talk with their physician before using any therapy, including nutritional treatments. Even if the physician is not familiar with or does not approve of the treatment, he or she may know about specific cautions or contraindications, due to a patient's medical condition.

93. Peripheral Neuropathy Nutritional Support Article In one study, three patients with severe diabetic peripheral neuropathy were Ziegler, D. Treatment of Symptomatic diabetic Peripheral Neuropathy With http://www.vrp.com/art/555.asp

Email this article to a friend Peripheral Neuropathy Nutritional Support Ward Dean M.D. Peripheral neuropathy is a condition that has many causes. The symptoms are numbness, irritation and pain, usually in the extremities. Its most likely causes are diabetes (most common), nutritional deficiencies, excess alcohol intake, cancer, heavy metal accumulation (lead, mercury), or even a reaction to various medications. One key to treatment, therefore, is to try to find the cause. However when a cause cannot be readily determined, I recommend a shotgun approach, using a variety of supplements which have been demonstrated to be effective in treating this bothersome and often disabling condition. First, one of the most common causes of peripheral neuropathy is a thiamin deficiency - or an abnormal requirement for thiamin. For example, a child in Japan suffered from relapsing cases of severe neuropathy, debilitating muscle weakness, and difficulty maintaining his balance each time he had a febrile illness. Finally, the childs physicians began using high doses of thiamin every time he became sick. Using doses of 500 mg of thiamin per day, neuropathy symptoms would resolve within two weeks (as opposed to two months, without thiamin). In addition, the frequency of illness was reduced from 2 to 4 episodes per year when thiamin was not used, compared to no more than one seasonal illness per year with thiamin. Thiamin was effective in preventing further episodic neurologic attacks at 500 mg per day in this patient. Thiamin, in doses of 20 to 2400 mg/day, has been given to patients with various metabolic diseases, without adverse effects. (Kinoshita 1997) .

94. Antidepressants For Diabetic Neuropathy And Postherpetic Neuralgia Antidepressants for diabetic neuropathy and postherpetic neuralgia. http://www.jr2.ox.ac.uk/bandolier/booth/painpag/Chronrev/antidc/antidep.html

@import "../../../../styles/advanced.css"; Skip navigation Acute Pain Chronic Pain General Antidepressants for diabetic neuropathy and postherpetic neuralgia Clinical bottom line Antidepressants are effective treatments for diabetic neuropathy (NNT 3.4, 95% confidence interval 2.6 to 4.7) and postherpetic neuralgia (NNT 2.1, 1.7 to 3.0) compared with placebo. The NNH for any patient to have a minor adverse effect with antidepressant was 2.7 (2.1 to 3.9) and for a major adverse effect was 17 (10-43). For over thirty years the management of neuropathic pain has involved the use of both antidepressants and anticonvulsants, but which drug class should be first line choice remains unclear. The dogma that the character of the pain was predictive of the response, burning pain responding to antidepressants and shooting pain to anticonvulsants, was shown to be incorrect in diabetic neuropathy, where patients experiencing both burning and shooting pain responded to tricyclic antidepressants. Most studies on neuropathic pain have involved diabetic neuropathy and postherpetic neuralgia, because these conditions represent the majority of patients with neuropathic pain. SYSTEMATIC REVIEW SL Collins et al. Antidepressants and anticonvulsants for diabetic neuropathy and postherpetic neuralgia: a quantitative systematic review. Journal of Pain and Symptom Management 2000 20: 449-458.

95. MedlinePlus Medical Encyclopedia: Diabetic Neuropathy Nerve damage diabetic. Definition Return to top. diabetic neuropathy is a commoncomplication of diabetes mellitus in which nerves are damaged as a result http://www.nlm.nih.gov/medlineplus/ency/article/000693.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Diabetic neuropathy Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Diabetes and nerve damage Central nervous system Alternative names Return to top Nerve damage - diabetic Definition Return to top Diabetic neuropathy is a common complication of diabetes mellitus in which nerves are damaged as a result of hyperglycemia (high blood sugar levels). Causes, incidence, and risk factors Return to top People with diabetes commonly develop temporary or permanent damage to nerve tissue. Nerve injuries are caused by decreased blood flow and high blood-sugar levels , and are more likely to develop if blood-glucose levels are poorly controlled. Some diabetics will not develop nerve damage, while others may develop this condition relatively early. On average, the onset of symptoms occurs 10 to 20 years after diabetes has been diagnosed. Approximately 50% of people with diabetes will eventually develop nerve damage. Peripheral nerve injuries may affect cranial nerves or nerves from the spinal column and their branches. This type of neuropathy (nerve injury) tends to develop in stages. Early on, intermittent pain and

96. Diabetic Neuropathy diabetic neuropathy is a nerve disorder caused by diabetes. The symptoms ofdiabetic neuropathy vary. Numbness and tingling in feet are often the first http://mdchoice.com/Pt/Ptinfo/diabne.asp

Advertisement Sign up for a FREE disease newsletter: Select Disease Allergies Arthritis Cholesterol Depression Diabetes Hypertension Medical Information Arthritis Center Allergy Center Kid's Health Cancer Center ... Health News From our Sponsors Interactive Education Simulators PhotoRounds Medical Databases MEDLINE CancerLit AIDSLine Healthcare Employment About Us Editorial Board Our Company Contact Us We subscribe to the HONcode principles of the Health On the Net Foundation Spell Checker Search the Web's best medical sites Searches over 6,000 Medical Journals Health Information Thursday, September 08, 2005 Find more information about this topic from either the Web or the world's best medical journals by using the search boxes at the top of this page. Diabetic Neuropathy: The Nerve Damage of Diabetes What Is Diabetic Neuropathy? Diabetic neuropathy is a nerve disorder caused by diabetes. Symptoms of neuropathy include numbness and sometimes pain in the hands, feet, or legs. Nerve damage caused by diabetes can also lead to problems with internal organs such as the digestive tract, heart, and sexual organs causing indigestion, diarrhea or constipation, dizziness, bladder infections, and impotence. In some cases, neuropathy can flare up suddenly, causing weakness and weight loss. Depression may follow. While some treatments are available, a great deal of research is still needed to understand how diabetes affects the nerves and to find more effective treatments for this complication.

97. Diabetic Neuropathy diabetic neuropathy is a nerve disorder caused by diabetes. diabetic neuropathyappears to be more common in smokers, people over 40 years of age, http://mdchoice.com/pt/ptinfo/diabne.asp

Advertisement Sign up for a FREE disease newsletter: Select Disease Allergies Arthritis Cholesterol Depression Diabetes Hypertension Medical Information Arthritis Center Allergy Center Kid's Health Cancer Center ... Health News From our Sponsors Interactive Education Simulators PhotoRounds Medical Databases MEDLINE CancerLit AIDSLine Healthcare Employment About Us Editorial Board Our Company Contact Us We subscribe to the HONcode principles of the Health On the Net Foundation Spell Checker Search the Web's best medical sites Searches over 6,000 Medical Journals Health Information Thursday, September 08, 2005 Find more information about this topic from either the Web or the world's best medical journals by using the search boxes at the top of this page. Diabetic Neuropathy: The Nerve Damage of Diabetes What Is Diabetic Neuropathy? Diabetic neuropathy is a nerve disorder caused by diabetes. Symptoms of neuropathy include numbness and sometimes pain in the hands, feet, or legs. Nerve damage caused by diabetes can also lead to problems with internal organs such as the digestive tract, heart, and sexual organs causing indigestion, diarrhea or constipation, dizziness, bladder infections, and impotence. In some cases, neuropathy can flare up suddenly, causing weakness and weight loss. Depression may follow. While some treatments are available, a great deal of research is still needed to understand how diabetes affects the nerves and to find more effective treatments for this complication.

98. BOOK REVIEWS There are three major types of diabetic neuropathy, and they can affect virtuallyevery part of the body. Focal neuropathy affects the eyes, facial muscles, http://www.nfb.org/vod/vsum0016.htm

BOOK REVIEWS by Marilyn Helton Porch swings, overhead fans and meals prepared on the outdoor grill... Now, all you need to round out your lazy days of summer is a stack of good books. Here are my notes to help you select some topics in your area of interest. If you've had diabetes for more than 10 years, there's a good chance you're part of the 60% of diabetics who have developed diabetic neuropathy, a nerve disorder caused by diabetes. Significant clinical neuropathy can develop within the first 10 years after your diagnosis, and the risk increases the longer you have diabetes. There are three major types of diabetic neuropathy, and they can affect virtually every part of the body. Focal neuropathy affects the eyes, facial muscles, hearing, pelvis, lower back, thigh and abdomen. Diffuse (autonomic) neuropathy affects the heart, digestive system, sexual organs, urinary tract and sweat glands. Diffuse (peripheral) neuropathy affects the legs, feet, arms and hands. After his diagnosis of peripheral neuropathy, John Senneff, a retired attorney, found there was little information available as he sought to learn more about it. It is often called the "silent disease" because so few people talk about it, or have even heard its name, but Senneff has managed to explain it detail in his new book:

99. Diabetic Neuropathy diabetic neuropathy traditionally is considered progressive and irreversible andwill A prospective study of 29 patients with diabetic neuropathy and 47 http://www.circulatorboot.com/literature/neuropat.html

Diabetic Neuropathy Adler AI, Boyko EJ, Ahroni JH, Stensel V, Forsberg RC and Smith DG Risk factors for diabetic peripheral sensory neuropathy. Comments: "CAGE" is the acronym for cut down, annoyed by criticism, guilty about drinking and eye-opener drinks (Ewing JA: Detecting alcoholism: the CAGE questionnaire. JAMA 252: 1905-1907, 1984). The authors hypothesized that more healthy smokers continued smoking while the less healthy stopped. While the glycohemoglobin levels differed significantly between the neuropathy (11.6%) and non-neuropathy group (10.9%), both were high. One wonders if these patients would have fared better if they were followed in a diabetes specialty clinic rather than a general medical clinic. Adriaensen H, Plaghki L, Mathieu C, Joffroy A, Vissers K Armstrong DG, Lavery LA, Vazquez JR, Short B, Kimbriel HR, Nixon BP, Boulton AJ Clinical efficacy of the first metatarsophalangeal joint arthroplasty as a curative procedure for hallux interphalangeal joint wounds in patients with diabetes. Comments: One always worries about healing, infection and long term benefit after surgery on a diabetic foot, especially one with neuropathy. This was a retrospective case record study in patients without significant vascular disease or infection. The control and surgery patients were quite similar except for slightly better glycemic control in the surgical group (GHb% 7.9+/-1.4 vs 8.4+/-1.2). Such patients generally heal their ulcers with offloading and time. Surgical patients, of course, commonly enjoy a few days in the hospital off their feet and tend to restrict ambulation after their surgery more than nonsurgical patients. The surgeons doing the procedures do not tell us why they chose some patients to operate on and not others. Obviously, a prospective study with a sham-surgery control group would be desirable.

100. HONselect Information on , Medical hierarchy and definition, Research Articles,Web resources, Medical Images, Medical News, Medical Conferences, Clinical Trials http://www.hon.ch/HONselect/Selection/C19.246.447.html

InitBulle("navy","#F8F8F8","#000066",1); HONcode sites All Web sites HONselect News ... Images HONselect Search English French German Spanish Portuguese the word the part of word in MeSH term in MeSH term and description Information on "": Medical hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Hierarchy English Browse New search Web resources for Browse New search Medical image(s) for Browse New search Medical News for No results for this term. More health news Browse New search Scientific articles from MEDLINE for English All recent articles Therapy: by recall by ... New search Clinical Trials for No results for this term. Consult others clinical trials from ClinicalTrials.gov Browse New search Medical Conferences/Events for No results for this term. Consult HON's world-wide database of medical meetings Browse New search Refine the search for Broader term(s): Browse New search Most frequently used terms List of Rare Disease ... Contact http://www.hon.ch/HONselect/Selection/C19.246.447.html Last modified: Tue Sep 6 2005

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