41. Diabetes Insipidus Detailed information on diabetes insipidus, including causes, symptoms, diagnosis,and treatment. http://www.healthsystem.virginia.edu/uvahealth/peds_diabetes/di.cfm

[ Skip Navigation ] Health System Home For Health Answers Healthcare Professionals ... Advanced Search Health System Search Search for Information People UVa Home Health System News Health System Events (all) Health System Publications ... Making a Gift Topics Adolescent Medicine Allergy/Asthma/Immunology Blood Disorders Burns Cancer Common Injuries/Poison Tips Craniofacial Anomalies Dermatology Diabetes/Endo/Metabolism Eye Care Genitourinary/Kidney High-Risk Newborn High-Risk Pregnancy Infectious Diseases Medical Genetics Mental Health Nervous System Disorders Normal Newborns Oral Health Orthopaedics Pediatric Surgery Respiratory Disorders Terminal Illness in Children Transplantation UVa Health Topics A to Z FIND A DOCTOR Pediatric Endocrinology Pediatric Neurosurgery MAKE AN APPOINTMENT ... CLINICAL TRIALS Search This Site Diabetes Insipidus What is diabetes insipidus? Diabetes insipidus is a condition that results from insufficient production of the antidiuretic hormone (ADH), a hormone that helps the kidneys and body conserve the correct amount of water. Normally, the antidiuretic hormone controls the kidneys' output of urine. It is secreted by the hypothalamus (a small gland located at the base of the brain) and stored in the pituitary gland and then released into the bloodstream. ADH is secreted to decrease the amount of urine output so that dehydration does not occur. Diabetes insipidus, however, causes excessive production of very diluted urine and excessive thirst. The disease is categorized into groups:

42. Home Page: Diabetes Insipidus Mutation Database Mutations that cause nephrogenic or neurogenic diabetes insipidus have beenidentified in the following genes. arginine vasopressin receptor 2 (AVPR2) http://www.medicine.mcgill.ca/nephros/

Gene Gene AVP Gene ... Other Sites of Interest Nephrogenic and Neurogenic Diabetes Insipidus McGill University and McGill University Health Centre This website is supported by grants to Daniel Bichet Kenneth Morgan from the Canadian Genetic Diseases Network (Federal Networks of Centres of Excellence Program). This website was implemented by Joyce Crumley (2000). Mutations that cause nephrogenic or neurogenic diabetes insipidus have been identified in the following genes: arginine vasopressin receptor 2 ( aquaporin-2 ( prepro-arginine-vasopressin-neurophysin II ( AVP Information on mutations can be retrieved by: name type of mutation location in the gene functional studies For further information, click on one of the menu links at the top of the page. Acknowledgements While reasonable effort has been made to ensure that this website is of high quality, the Montreal Diabetes Insipidus Group makes no warranty, express or implied, as to the accuracy of the information or its suitability for any specific purpose. The Group will not be responsible for any consequences arising out of any inaccuracies or omissions, nor be liable for damages, direct or indirect, that result from the use of this website. Page last modified: 24 October 2003 Site last modified: 24 October 2003

43. Diabetes Insipidus a CHORUS notecard document about diabetes insipidus. http://chorus.rad.mcw.edu/doc/01040.html

CHORUS Collaborative Hypertext of Radiology Multisystem entities About CHORUS Search Feedback diabetes insipidus hypothalamic rare genetic disorder pituitary destruction: craniopharyngioma, surgery, trauma, meningitis, histiocytosis X psychogenic (water intoxication) compulsive intake of large amounts of fluid inhibition of normal vasopressin production primary nephrogenic rare sex-linked recessive disorder (infants and young males) tubules and collecting system unresponsive to vasopressin secondary nephrogenic drug toxicity, analgesic nephropathy, sickle cell, hypokalemia, hypercalcemia, chronic uremic nephropathy, postobstructive nephropathy, amyloidosis, sarcoidosis Yong H. Hahn, MD - 2 February 1995 Last updated 26 May 2004 Related CHORUS documents: eosinophilic granuloma Hand-Schueller-Christian disease histiocytosis X Letterer-Siwe disease ... pancreatic islet-cell tumors Search for related articles: AJR American Journal of Roentgenology PubMed : index to biomedical literature ... Medical College of Wisconsin

44. Introduction: Autoimmune Diabetes Insipidus - WrongDiagnosis.com Introduction to Autoimmune diabetes insipidus as a medical condition includingsymptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis. http://www.wrongdiagnosis.com/a/autoimmune_diabetes_insipidus/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Autoimmune Diabetes Insipidus Next sections Basic Summary for Autoimmune Diabetes Insipidus Symptoms of Autoimmune Diabetes Insipidus Glossary for Autoimmune Diabetes Insipidus Next chapters: Autoimmune Endometriosis Chronic Fatigue Syndrome Polychondritis Relapsing Polychondritis ... Feedback Introduction: Autoimmune Diabetes Insipidus Autoimmune Diabetes Insipidus: Autoimmune disorder leading to diabetes insipidus Researching symptoms of Autoimmune Diabetes Insipidus: Further information about the symptoms of Autoimmune Diabetes Insipidus is available including a list of symptoms of Autoimmune Diabetes Insipidus , or alternatively return to research other symptoms in the symptom center Contents for Autoimmune Diabetes Insipidus: Basic Summary for Autoimmune Diabetes Insipidus Symptoms of Autoimmune Diabetes Insipidus Glossary for Autoimmune Diabetes Insipidus Diseases Did we miss something? Please provide feedback or suggestions By using this site you agree to our . Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our

45. Introduction: Diabetes Insipidus - WrongDiagnosis.com Introduction to diabetes insipidus as a medical condition including symptoms,diagnosis, misdiagnosis, treatment, prevention, and prognosis. http://www.wrongdiagnosis.com/d/diabetes_insipidus/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Diabetes Insipidus Next sections Basic Summary for Diabetes Insipidus Prevalence and Incidence of Diabetes Insipidus Types of Diabetes Insipidus Causes of Diabetes Insipidus ... Symptoms of Diabetes Insipidus Next chapters: Kidney Dialysis Primary amyloidosis Dialysis-related amyloidosis Renal Tubular Acidosis ... Feedback Introduction: Diabetes Insipidus Diabetes Insipidus: Diabetes insipidous is a metabolic disorder involving the pituitary gland and the kidneys. Although it shares the name, diabetes insipidous is not a subtype nor in any way related to the more common sugar diabetes (diabetes mellitus). Researching symptoms of Diabetes Insipidus: Further information about the symptoms of Diabetes Insipidus is available including a list of symptoms of Diabetes Insipidus , other diseases that might have similar symptoms in differential diagnosis of Diabetes Insipidus , or alternatively return to research other symptoms in the symptom center Misdiagnosis and Diabetes Insipidus: Research more detailed information about misdiagnosis of Diabetes Insipidus underlying causes of Diabetes Insipidus (possibly misdiagnosed), or research

46. Diabetes Insipidus Defines diabetes insipidus and reviews the mechanics of normal fluid regulation.Discusses the different forms of the condition and the tests used to http://kidney.niddk.nih.gov/kudiseases/pubs/insipidus/

Email To A Friend PDF Version Home : Diabetes Insipidus Diabetes Insipidus On this page: Diabetes Insipidus versus Diabetes Mellitus Normal Fluid Regulation in the Body Central DI Nephrogenic DI ... For More Information Diabetes insipidus (DI) causes frequent urination. The large volume of urine is diluted, mostly water. To make up for lost water, you may feel the need to drink large amounts. You are likely to urinate frequently, even at night, which can disrupt sleep or, on occasion, cause bedwetting. Because of the excretion of abnormally large volumes of dilute urine, you may quickly become dehydrated if you do not drink enough water. Children with DI may be irritable or listless and may have fever, vomiting, or diarrhea. In its clinically significant forms, DI is a rare disease. Top Diabetes Insipidus versus Diabetes Mellitus DI should not be confused with diabetes mellitus, which results from insulin deficiency or resistance leading to high blood glucose. Diabetes insipidus and diabetes mellitus are unrelated, although they can have similar signs and symptoms, like excessive thirst and excessive urination. Diabetes mellitus (DM) is far more common than DI and receives more news coverage. DM has two forms, referred to as type 1 diabetes (formerly called juvenile diabetes, or insulin-dependent diabetes mellitus, or IDDM) and type 2 diabetes (formerly called adult-onset diabetes, or noninsulin-dependent diabetes mellitus, or NIDDM). DI is a different form of illness altogether.

47. Nephrogenic Diabetes Insipidus Penn State Hershey Medical Center provides world class care and services to patients. http://www.hmc.psu.edu/healthinfo/no/nephrogenicdiabetes.htm

48. Diabetes Insipidus Penn State Hershey Medical Center provides world class care and services to patients. http://www.hmc.psu.edu/healthinfo/d/diabetesinsipidus.htm

49. Diabetes Insipidus - General Information General information of diabetes insipidus. diabetes insipidus is caused bythe inability of the kidneys to conserve water, which leads to frequent http://chinese-school.netfirms.com/diabetes-insipidus.html

Corporate Services Other Services Private Instruction Invest in China ... Contact Us Content Diabetes Diabetes Information Diabetes Facts History of Diabetes ... Signs of Diabetes Also: Diabetes Sign Symptoms Type 2 Diabetes Symptoms Also: Type II Diabetes Symptoms Gestational Diabetes Symptoms Symptoms, Juvenile Diabetes Also: Diabetes Symptoms in Child Glucose (see also Blood Glucose Glucose Level Also: Blood Glucose Level Glucose Meter Also: Blood Glucose Meter Glucose Monitor Also: Blood Glucose Monitor Glucose Test Also: Glucose Tolerance Test Glucose Intolerance Diabetes Diet Diabetes Food ... Diabetes is the No. 6 leading causes of deaths in the United States, according to 2001 data from the United States National Center for Health Statistics. Diabetes Insipidus Definition Diabetes insipidus is caused by the inability of the kidneys to conserve water, which leads to frequent urination and pronounced thirst. Causes, incidence, and risk factors Diabetes insipidus is an uncommon condition that occurs when the kidneys are unable to conserve water as they perform their function of filtering blood. The amount of water conserved is controlled by antidiuretic hormone (ADH, also called vasopressin). ADH is a hormone produced in a region of the brain called the hypothalamus. It is then stored and released from the pituitary gland, a small gland at the base of the brain.

50. Nephrogenic Diabetes Insipidus - General Information General information of nephrogenic diabetes insipidus. http://chinese-school.netfirms.com/diabetes-insipidus-nephrogenic.html

Corporate Services Other Services Private Instruction Invest in China ... Contact Us Content Diabetes Diabetes Information Diabetes Facts History of Diabetes ... Signs of Diabetes Also: Diabetes Sign Symptoms Type 2 Diabetes Symptoms Also: Type II Diabetes Symptoms Gestational Diabetes Symptoms Symptoms, Juvenile Diabetes Also: Diabetes Symptoms in Child Glucose (see also Blood Glucose Glucose Level Also: Blood Glucose Level Glucose Meter Also: Blood Glucose Meter Glucose Monitor Also: Blood Glucose Monitor Glucose Test Also: Glucose Tolerance Test Glucose Intolerance Diabetes Diet Diabetes Food ... Diabetes is the No. 6 leading causes of deaths in the United States, according to 2001 data from the United States National Center for Health Statistics. Nephrogenic Diabetes Insipidus Alternative names Nephrogenic diabetes insipidus; Acquired nephrogenic diabetes insipidus; Definition Nephrogenic diabetes insipidus is a disorder characterized by the passage of large volumes of urine due to a defect of the kidney tubules. See also diabetes insipidus-central. Causes, incidence, and risk factors

51. Central Diabetes Insipidus Familial diabetes insipidus (very rare). Point mutation in ADH precursor gene.Precursor accumulates; Toxicity to ADH synthesizing cells http://www.fpnotebook.com/REN25.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Nephrology Endocrinology Sodium ... Diabetes Insipidus Central Diabetes Insipidus Nephrogenic Diabetes Insipidus Laboratory Fluid Deprivation Test Hare-Hickey Test ... dDAVP Central Diabetes Insipidus Central DI Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Practice Management Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Nephrology Index Acid and Base Disorders Calcium Chloride Cardiovascular Medicine Dermatology Edema Endocrinology Examination Failure Glomerulus Laboratory General Pulmonology Magnesium Neurology Pharmacology Phosphorus Potassium Prevention Radiology Sodium Surgery Tubule Page Endocrinology Index Sodium DI Sodium DI Central Sodium DI Nephrogenic Definition Antidiuretic Hormone (ADH) deficiency Pathophysiology Polyuria Decreased ADH release Permanent Polyuria Central lesion above median eminence Transient Polyuria Central lesion below median eminence ADH passes via hypothalamus to portal capillaries Results in ADH release below the median eminence Etiology Idiopathic (30%) Autoimmune disease (common) Lymphocyte inflammation Pituitary stalk (thickened stalk on MRI) Posterior pituitary Anterior Pituitary deficiency Growth Hormone ACTH deficient Familial Diabetes Insipidus (very rare)

52. Nephrogenic Diabetes Insipidus Endocrinology Sodium diabetes insipidus Central diabetes insipidus.Nephrogenic diabetes insipidus Nephrogenic diabetes insipidus. Nephrogenic DI http://www.fpnotebook.com/REN26.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Nephrology Endocrinology Sodium ... Central Diabetes Insipidus Nephrogenic Diabetes Insipidus Laboratory Fluid Deprivation Test Hare-Hickey Test Pharmacology ... dDAVP Nephrogenic Diabetes Insipidus Nephrogenic DI Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Practice Management Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Nephrology Index Acid and Base Disorders Calcium Chloride Cardiovascular Medicine Dermatology Edema Endocrinology Examination Failure Glomerulus Laboratory General Pulmonology Magnesium Neurology Pharmacology Phosphorus Potassium Prevention Radiology Sodium Surgery Tubule Page Endocrinology Index Sodium DI Sodium DI Central Sodium DI Nephrogenic Definition Deficient response by kidney to Antidiuretic Hormone Pathophysiology ADH fails increasing collecting duct water permeability Failed countercurrent mechanism Inadequate generation of hypertonic interstitium Causes Congenital Chronic disease of renal medulla Medullary cystic disease Pyelonephritis Protein deficient diet Salt deficient diet Hypercalcemia Hypokalemia Amyloidosis Multiple Myeloma Medications Demeclocycline Lithium Glyburide Diagnosis Fluid Deprivation Test No response to water deprivation No response to exogenous ADH administration

53. Diabetes Insipidus - Keep Kids Healthy Conditions A discussion of diabetes insipidus, which can cause increased urination andexcessive thirst, leading to hypernatremia and dehydration. http://www.keepkidshealthy.com/welcome/conditions/diabetes_insipidus.html

Bookstore Site Map Contact Us Help ... What's New? Search this site: Advanced Search Main Menu Useful Tools Index of Topics Pediatric Problems Parenting Tips ... Web Links Online Resources What's New Reviews Growth Charts Online Forums ... Height Calculator Newsletters: Subscribe to get free news, tips and updates. Recommend Us tell a friend about us or email this page to a friend Main Diseases and Conditions Diabetes Insipidus Diabetes inspidus (DI) is a disorder that causes increased urination ( polyuria ) and increased thirst . It is caused by either a decrease in the hormone arginine vasopressin ( central DI ), or because the kidney does not respond correctly to the hormone ( nephrogenic DI ). Arginine vasopressin is a hormone that normally stimulates the collecting ducts of the kidney to reabsorb water, so if it is not able to work correctly, the kidney produces a very large volume of dilute urine. Arginine vasopressin is normally produced in the hypothalamus , and so there can be a decrease in the its production caused by any condition that disrupts the hypothalamus, including brain tumors and head trauma, and some inherited conditions (septo-optic dysplasia). Nephrogenic DI can either be inherited or it can be a side effect of some medications, including Lithium, and some chronic conditions, such as sickle cell anemia, pyelonephritis, and urinary tract obstructions. In addition to increased thirst and urination, other symptoms can include irritability, poor growth, nocturnal enuresis (wetting the bed at night), and if your child is not able to drink enough fluids to keep up with the large amount of fluid being lost from excessive urination, then your child may develop

54. AllRefer Health - Nephrogenic Diabetes Insipidus (Acquired Nephrogenic Diabetes diabetes insipidus Nephrogenic (Acquired Nephrogenic diabetes insipidus,Nephrogenic diabetes insipidus) information center covers causes, prevention, http://health.allrefer.com/health/diabetes-insipidus-nephrogenic-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Nephrogenic Diabetes Insipidus Diabetes Insipidus - Nephrogenic Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : Acquired Nephrogenic Diabetes Insipidus, Nephrogenic Diabetes Insipidus Definition Nephrogenic diabetes insipidus is a disorder characterized by the passage of large volumes of urine due to a defect of the kidney tubules. See also diabetes insipidus-central Male Urinary System Antidiuretic hormone ADH vasopressin ) is a hormone produced in the hypothalamus of the brain. It concentrates the urine by triggering the kidneys to reabsorb water into the blood stream rather than excreting water into the urine.

55. AllRefer Health - Central Diabetes Insipidus (Central Diabetes Insipidus) diabetes insipidus Central (Central diabetes insipidus) information centercovers causes, prevention, symptoms, diagnosis, treatment, incidence, http://health.allrefer.com/health/diabetes-insipidus-central-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Central Diabetes Insipidus Diabetes Insipidus - Central Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : Central Diabetes Insipidus Definition A condition marked by extreme thirst and excessive urine output caused by a deficiency of a hormone ( vasopressin ) that normally would limit the amount of urine made. See also diabetes insipidus - nephrogenic Endocrine Glands Central diabetes insipidus is a rare condition caused by damage to the hypothalamus or pituitary gland in the brain. Damage may be related to surgery, infection, inflammation, tumor , or injury to the head . Sometimes the cause remains unknown. Very rarely, diabetes insipidus can be caused by a genetic defect.

56. BBC - Health - Conditions - Diabetes Insipidus A feature on diabetes insipidus. When diabetes insipidus (DI) exists, thebody either doesn t produce enough ADH or it doesn t respond correctly to the http://www.bbc.co.uk/health/conditions/diabetesinsipidus1.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index FRIDAY 9th September 2005 Text only BBC Homepage Lifestyle Health ... Help Like this page? Send it to a friend! Diabetes insipidus Dr Rob Hicks Although most people would have heard of diabetes mellitus or 'sugar diabetes' few would have come across the condition called diabetes insipidus, a completely different and unrelated condition. In this article What happens? What are the effects? Two forms Diagnosis ... Stemming the flow What happens? Many different hormones help to control metabolic activities within the body. One of these is called anti-diuretic hormone (ADH) and its function is to help control the balance of water in the body. It does this by regulating the production of urine. ADH is produced by the hypothalamus and then stored in the pituitary gland until it's needed. When diabetes insipidus (DI) exists, the body either doesn't produce enough ADH or it doesn't respond correctly to the effects of ADH. What are the effects? Someone with DI passes excessive amounts of urine and in a twenty-four hour period over three litres may be passed Someone with DI passes excessive amounts of urine and in a twenty-four hour period over three litres may be passed. They're always thirsty and find themselves drinking almost constantly. Disturbed sleep and disturbed daytimes are the consequence of having to pass water so frequently - they may need to pass water every 15 to 20 minutes.

57. Diabetes Insipidus Adam P. Evaluation and management of diabetes insipidus. Am Fam Phy 1997;55214652 . 20 years of experience in idiopathic central diabetes insipidus. http://www.endocrinology.med.ucla.edu/diabetes_insipidus.htm

UCLA Endocrinology Home Up Contents Forms Diabetes Insipidus Mark Goodarzi, M.D. I. Normal physiology L-Arginine vasopressin (AVP, ADH), a nonapeptide, is synthesized in the bodies of magnocellular neurons in the paired supraoptic nuclei and paraventricular (lateral to the 3 rd Other effects of AVP: acts at a pressor agent at supraphysiologic levels (as in severe hypovolemia) by binding V1 receptors on blood vessels, which increase intracellular calcium and cause smooth muscle contraction. Regulation of AVP release: Integration of AVP secretion and thirst maintains plasma osmolality tightly at 280-290 mOsm/kg. Plasma osmolality: Anterior hypothalamic osmoreceptors (anterior to the 3 rd Plasma volume: Baroreceptors (stimulated by hypervolemia, inhibited by hypovolemia) inhibit AVP release via cranial nerves IX, X. The atrial cardiopulmonary low-pressure baroreceptors are less sensitive than osmoreceptors, requiring a 5-10% decrease in blood volume before AVP is released. Severe hypovolemia, however, triggers the sino-aortic high-pressure baroreceptors to cause exponential increases in AVP, which may be high enough to exert a pressor effect. Interaction of osmo- and baroreceptors: A decrease in left atrial pressure (as in hypovolemia, hypotension) leads to a reduction of the osmotic threshold and increases the sensitivity for osmotic AVP release. Volume expansion dampens the sensitivity for osmotic AVP release.

58. Dr. Koop - Diabetes Insipidus - Nephrogenic Nephrogenic diabetes insipidus is a disorder characterized by the passage oflarge volumes of urine due to a defect of the kidney tubules. See also . http://www.drkoop.com/ency/93/000511.html

Home Health Reference Diabetes insipidus - nephrogenic Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library Inside DrKoop News Archive Animations Health Videos Health Tools ... Newsletters Diabetes insipidus - nephrogenic Injury Disease Nutrition Poison ... Prevention Diabetes insipidus - nephrogenic Definition: Nephrogenic diabetes insipidus is a disorder characterized by the passage of large volumes of urine due to a defect of the kidney tubules. See also diabetes insipidus-central Alternative Names: Nephrogenic diabetes insipidus; Acquired nephrogenic diabetes insipidus; Causes, incidence, and risk factors: Antidiuretic hormone ( ADH ; vasopressin) is a hormone produced in the hypothalamus of the brain. It concentrates the urine by triggering the kidneys to reabsorb water into the blood stream rather than excreting water into the urine. Nephrogenic diabetes insipidus involves a defect in the kidney tubules (the portion of the kidneys that causes water to be excreted or reabsorbed). The specific kidney defect is usually a partial or complete failure of special receptors located on or within the kidney tubules to respond to ADH, the hormone that transmits the instruction to concentrate the urine to the inside of the cells.

59. Dr. Koop - Diabetes Insipidus - Central Central diabetes insipidus is a rare condition marked by extreme thirst andexcessive urine output caused by a deficiency of the hormone that normally http://www.drkoop.com/ency/93/000460.html

Home Health Reference Diabetes insipidus - central Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library Inside DrKoop News Archive Animations Health Videos Health Tools ... Newsletters Diabetes insipidus - central Injury Disease Nutrition Poison ... Prevention Diabetes insipidus - central Definition: Central diabetes insipidus is a rare condition marked by extreme thirst and excessive urine output caused by a deficiency of the hormone vasopressin that normally would limit the amount of urine made. See also diabetes insipidus - nephrogenic Alternative Names: Central diabetes insipidus Causes, incidence, and risk factors: Central diabetes insipidus is a rare condition caused by damage to the hypothalamus or pituitary gland in the brain. Damage may be related to surgery, infection, inflammation, tumor , or injury to the head . Sometimes the cause remains unknown. Very rarely, diabetes insipidus can be caused by a genetic defect. Normally, the hypothalamus in the brain makes vasopressin, a hormone that causes the kidneys to conserve water by making concentrated urine. In diabetes insipidus , there is a lack of vasopressin. Without vasopressin, the kidneys fail to reabsorb excess filtered water. This results in a rapid loss of water from the body in the form of dilute urine.

60. Diabetes Insipidus - Endocrinology Health Guide Health Guide on diabetes insipidus, a condition that results from insufficientproduction of the antidiuretic hormone. http://www.umm.edu/endocrin/diabins.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Endocrinology Health Guide... Pituitary Gland Disorders... Pituitary Tumors Acromegaly ... Glossary Related Resources Within UMM Endocrinology Joslin Diabetes Center School of Medicine Endocrinology Site Translate using Google to Spanish German French Italian Portuguese Endocrinology Health Guide Diabetes Insipidus F A C T : Though produced by the hypothalamus, the portion of the brain that stimulates the pituitary gland, the antidiuretic hormone, is actually stored and released into the bloodstream by the pituitary gland. What is diabetes insipidus? Diabetes insipidus is a condition that results from insufficient production of the antidiuretic hormone by the hypothalamus, the portion of the brain that stimulates the pituitary gland. Normally, the antidiuretic hormone controls the kidneys' output of urine. Diabetes insipidus causes excessive thirst and excessive production of very diluted urine. Causes of diabetes insipidus: Diabetes insipidus can be caused by several conditions, including: malfunctioning hypothalamus malfunctioning pituitary gland damage to hypothalamus or pituitary gland during surgery brain injury tumor tuberculosis blockage in the arteries leading to the brain encephalitis meningitis sarcoidosis (a rare inflammation of the lymph nodes and other tissues throughout the body) What are the symptoms of diabetes insipidus?

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