41. CREUTZFELDT-JAKOB DISEASE AND RELATED DISORDERS INTRODUCTION creutzfeldtjakob disease is a disease of bizarre nature that creutzfeldt-jakob disease occurs on a worldwide basis of 1 per million http://www.biomed.lib.umn.edu/hw/creutzfeld.html

From: Champion Expanding Encyclopedia Of Mortuary Practices Number 625. pp 2514-17, 1995 CREUTZFELDT-JAKOB DISEASE AND RELATED DISORDERS Part 1 By James H. Bedino, Chemist/Dir. Research, The Champion Company ABSTRACT : An in-depth discussion and explanation of Creutzfeldt-Jakob disease along with several related prion driven disorders are covered for the elucidation and education of the embalmer. Early history of the various diseases is outlined with the interrelationships to kuru, scrapie, BSE and other similar neuro-degenerative diseases. The bizarre nature of the causative agent is discussed in detail along with its remarkable survivability. The dangers and concerns that embalmers have are delineated and placed in perspective. A suggested protocol to minimize risk during embalming is presented. A summation and suggestions for embalmers completes the article. INTRODUCTION : Creutzfeldt-Jakob disease is a disease of bizarre nature that almost every embalmer or funeral director has heard of but has virtually no idea concerning the facts and realities of the disease itself. There is a very small amount of information that has been available to the embalming profession concerning Creutzfeldt-Jakob disease and unfortunately it is either incomplete, misleading or outright incorrect. There is more conjecture and rumor involved with this disease than almost any other disease and there is virtually no valid information available to help the embalmer. This has resulted in a definite uncertainty and even panic in most situations involving embalmers when they encounter this disease during the course of their professional career. Nothing is more fearful than complete rack of information concerning a potentially deadly disease.

42. Creutzfeldt-Jakob Disease - Wikipedia, The Free Encyclopedia creutzfeldtjakob disease (CJD) is a very rare and incurable brain creutzfeldt-jakob disease and related transmissible spongiform encephalopathies. http://en.wikipedia.org/wiki/Creutzfeldt-Jakob_disease

Wikimedia needs your help in the final days of its fund drive. See our fundraising page Over US$225,000 has been donated since the drive began on 19 August. Thank you for your generosity! Creutzfeldt-Jakob disease From Wikipedia, the free encyclopedia. Creutzfeldt-Jakob disease This article needs to be cleaned up to conform to a higher standard of quality. This article has been tagged since April 2005. See How to Edit and Style and How-to for help, or this article's talk page Creutzfeldt-Jakob Disease (CJD) is a very rare and incurable brain disease that is ultimately fatal. It is the most common of the transmissible spongiform encephalopathies (TSEs). TSEs (also known as prion diseases) are caused by a unique type of infectious agent called prions, an abnormally- structured form of a protein found in the brain. Other prion diseases include Gerstmann-Str¤ussler-Scheinker syndrome (GSS), fatal familial insomnia (FFI) and kuru in humans, as well as BSE and scrapie in animals. Contents Clinical features of CJD Prions Diagnosis Blood donor restrictions ... edit Clinical features of CJD Although CJD is the most common human prion disease, it is still extremely rare and only occurs in about one out of every one million people. It usually affects people aged 45-75, most commonly appearing in people between the ages of 60-65. The exception to this is the more recently-recognised 'variant' CJD (vCJD), which occurs in younger people. The first

43. Texas Department Of State Health Services, IDEAS > Creutzfeldt Jakob Disease Substantive information regarding CJD from the Texas Department of State Health Services. http://www.tdh.state.tx.us/ideas/creutzfeldt-jakob/

Click Here for Requested Information and Page Content Diseases: A-C Amebiasis Anthrax Arboviral Encephalitides ... Sitemap/Alphabetical Listing of Diseases and Topics Your Location: IDEAS Home Creutzfeldt-Jakob Disease (CJD) Creutzfeldt-Jakob Disease (CJD) ICD-9 046.1, ICD-10 A81.0 FAQs Data Reporting Other Sites What is CJD? What Are CJD's Signs And Symptoms? What Causes CJD? How Do You Get CJD? The first likely case of vCJD was identified in the United States in Florida in April 2002. This person is a 22-year-old United Kingdom (UK) citizen residing in the United States. Investigators concluded that the disease was contracted in the UK (Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, October 18, 2002). The first case of BSE in the United States was identified in an adult Holstein cow from Washington state on December 23, 2003. Preliminary reports suggest that the BSE-infected cow was imported into the United States from Canada in August 2001. The investigation of this case is in progress (Centers for Disease Control and Prevention, Division of Viral and Rickettsial Diseases). Last Updated: Wednesday, September 01, 2004

44. Mad Cows Disease, Creutzfeldt-Jakob Disease Informs of an simple heart test to find out whether patients have the fatal brainwasting condition, variant creutzfeldt-jakob disease, known as vCJD. http://www.cgi-installer-software.com/sites/hospitalweb/html/madcowsdisease.htm

Daily Mail, October 12, 2004 By Sarah Sims MAD COWS DISEASE, Creutzfeldt-Jakob Disease, Test that can rule out mad cow fears. The world's first test for the human form of mad cow disease has been developed by British scientists and is set to be available to doctors next year. Experts at the Manchester Royal Infirmary have invented a simple, painless heart test which takes just ten minutes to find out whether patients have the fatal brain-wasting condition, variant Creutzfeldt-Jakob Disease, known as vCJD. The breakthrough could offer peace of mind to 6,000 people in Britain who have been told that they may have contracted the deadly disease through a blood transfusion or receiving blood plasma products. The test would rule out the possibility that they had the disease. Dr Chris Pomfrett has devised the heartbeat test which hospital doctors or GPs can perform to discover if someone has vCJD up to five years before they experience any symptoms. The wireless belt device is strapped around the chest and works by measuring the heartbeat 1,000 times a second for ten minutes, which experts then use to look for the signature pattern of vCJD. Dr Pomfrett says: `In each of the vCJD patients it worked 100 per cent as it picked up the same signature.

45. Creutzfeldt-Jakob Disease - MayoClinic.com You ve probably heard of mad cow disease, but you may not be as familiar with Creuztfeldtjakob disease, a degenerative brain disorder. http://www.mayoclinic.com/invoke.cfm?id=DS00531

46. Health Canada - Diseases - Mad Cow Disease (BSE) New Window creutzfeldtjakob disease (CJD) in Canada Public Health Agency of Canada Information on Variant creutzfeldt-jakob disease (vCJD) - Human Form http://www.hc-sc.gc.ca/english/diseases/bse/

47. Health Canada - Creutzfeldt-Jakob Disease (Variant CJD) - First One of Health Canada s mandates is to reduce the incidence of disease, conditions and personal injuries. http://www.hc-sc.gc.ca/english/diseases/cjd/

48. Alzheimer's Society - CJD Support Network UK support network for all forms of creutzfeldtjakob disease. Offers information about the group as well as the disorder and contact details. http://www.alzheimers.org.uk/CJD

breadCrumbs("http://www.alzheimers.org.uk","/","index.htm","crumb","crumb","crumb","0"); Contact us Make a donation Membership Shop ... Fundraising events The CJD Support Network is now an independent charity. The contact details are: CJD Support Network Birchwood, Heath Top Ashley Heath Market Drayton Shropshire CJD Support Network helpline: 01630 673973 Email support@cjdsupport.net Website http://www.cjdsupport.net This page should redirect you to the page you require. If not, please click http://www.cjdsupport.net back to top Privacy policy Feedback Credits Contact us ... Links

49. CJD : The Department Of Health - P&G: Health Topics: CJD details for organisations concerned with creutzfeldtjakob disease (CJD) and Bovine Current Page Creutzfeld-jakob disease (CJD). CJD publications http://www.dh.gov.uk/PolicyAndGuidance/HealthAndSocialCareTopics/CJD/fs/en

@import "/pages/css-p/layout_101.css"; @import "/pages/css/core_standard.css"; @import "/pages/css/core_modules.css"; @import "/pages/css/core_links.css"; @import "/pages/css/core_buttons.css"; @import "/pages/css/core_forms.css"; @import "/pages/css/core_tables.css"; @import "/pages/css/core_corners.css"; @import "/pages/default/css/brnd_buttons.css"; @import "/pages/default/css/brnd_forms.css"; @import "/pages/default/css/brnd_links.css"; @import "/pages/default/css/brnd_modules.css"; @import "/pages/default/css/brnd_standard.css"; @import "/pages/default/css/brnd_tables.css"; @import "/pages/default/css/brnd_corners.css"; @import "/pages/default/css/bspk_standard.css"; @import("/pages/css/standard_fix_ie51mac.css"); Primary Navigation - link to other main sections from here Skip Navigation DH home Policy and guidance Publications and statistics ... Procurement and proposals You are here: DH home Policy and guidance Health and social care topics CJD CJD CJD publications and statistics Assessing the implications for blood donors if recipients are infected with vCJD Assessing the implications for blood donors if recipients are infected with vCJD CJD publications Key DH-published guidance documents, consultations and monthly statistics on CJD.

50. Creutzfeldt-Jakob Disease creutzfeldtjakob disease is a disorder involving rapid decrease of mental function and movement. These are abnormalities believed to be caused by damage http://www.healthcentral.com/ency/408/000788.html

Dr. Dean TV Specials Newsletters Home ... Health Tools Search Choose a Health Topic * All Health Topics * Acne Addictions AIDS/HIV Alcohol Abuse Allergies Alternative Medicine Alzheimer's Arthritis Asthma Attention Deficit Disorder (ADHD) Backache Bipolar Affective Disorder Birth Control Blood Blood Pressure Bone/Joint/Tendon Bowel Brain Breast cancer Cancer Cerebral Palsy Cholesterol Cramps Crohn's Disease Cysts Dental/Oral Depression Diabetes Diet, Fitness, Looks Disabled/Special Needs Drug Abuse Ear/Nose/Throat Eating/Appetite Eczema Encephalitis Eye/Vision Fatigue Fever Flu Food Poisoning Foot Gallbladder Gastrointestinal Genetic/Congenital GERD/Heartburn Hair Loss Hair/Scalp Headache Hearing Heart Disease, Stroke Heat/Sunstroke Hepatitis Hernia Herpes High Blood Pressure Hormonal Immune Disorders Immunizations/Vaccines Impotence Incontinence/Bladder Infections Injuries Kidney/Urinary Kids Learning Disabilities Liver Lung Cancer Men Menopause, Postmenopause Migraine Mobility/Balance Multiple Sclerosis Muscle Neural Nosebleeds Pain Parasites Pituitary PMS Pregnancy Prostate Cancer Prostate Disorders Psoriasis Psychological Raynaud's Disease Respiratory Reye Syndrome Rheumatoid Arthritis Schizophrenia Seniors Sensory Sexually Transmitted Disease Skin Sleep Speech Disorders Spinal Thyroid Trauma Weight Loss Women Yeast Infections Home Health Encyclopedia Creutzfeldt-Jakob disease Creutzfeldt-Jakob disease Injury Disease Nutrition Poison ... Prevention Creutzfeldt-Jakob disease Definition: Creutzfeldt-Jakob disease is a disorder involving rapid decrease of mental function and movement. These are abnormalities believed to be caused by damage done to the brain by a

51. Apr_Subject Frequently Asked Questions about creutzfeldtjakob disease (CJD) http://www.moh.govt.nz/moh.nsf/wpg_Index/About-CJD

ABOUT Frequently Asked Questions about Creutzfeldt-Jakob Disease (CJD) Updated August 2003 What is Creutzfeldt-Jakob Disease (CJD)? What is variant Creutzfeldt-Jakob Disease (vCJD)? What are the unique differences between CJD and vCJD? What causes variant CJD? ... top of page What is Creutzfeldt-Jakob Disease (CJD)? Creutzfeldt-Jakob Disease is a rare fatal brain disorder which was first recognised more than 80 years ago. There is no effective treatment and no reliable test to predict the disease. Approximately 85 percent of Creutzfeldt-Jakob Disease illnesses occur spontaneously without any known cause. Other causes include certain medical treatments that are no longer used such as human growth hormone injections and dural grafts (brain membrane). The symptoms may take 30 years to develop. Since the disease was identified by Dr. Alfons Maria Jakob in the 1920's, over 3,000 cases have been reported world-wide. What is variant Creutzfeldt-Jakob Disease (vCJD)? A new and more aggressive strain of the disease which was identified in the United Kingdom in 1996. It produces similar symptoms to classical CJD though the disease develops more rapidly. Variant CJD is thought to be contracted by eating meat infected with bovine spongiform encephalitis (BSE) which has been described as "mad cow disease". It historically has affected people in the 16 to 52 year age group. The mean age is 28 years.

52. Pathology Of Degenerative CNS Diseases creutzfeldtjakob disease (CJD) is rare, affecting less than one person in a million per Johnson RT, Gibbs CJ Jr. creutzfeldt-jakob disease and reltaed http://www-medlib.med.utah.edu/WebPath/TUTORIAL/CNS/CNSDG.html

CNS Degenerative Diseases Return to the tutorial menu. Alzheimer's Disease Senile dementia of the Alzheimer's type (SDAT), or Alzheimer's disease (AD) is becoming more common in developed nations as the population includes more and more older persons. There is no known cause for the disease. It is not known why some people present as early as 30 or 40 years of age with dementia while others do not present until their late 70's or 80's. Familial cases with a defined inheritance pattern account for only 5 to 10% of Alzheimer's disease. Familial cases tend to have an earlier age at onset. Genetic defects in familial cases have been identified on chromosomes 21, 19, 14, 12 and 1. The so-called "early onset" cases of AD in persons in their 30's, 40's, and 50's may have a genetic basis. Less than 1% of early onset AD cases are linked to a genetic defect on chromosome 21 (which may explain the appearance of Alzheimer's disease in persons with Down syndrome surviving to middle age) which affects amyloid precursor protein (APP), resulting in fibrillar aggregates of beta-amyloid that is toxic to neurons. About half of early onset AD cases are linked to mutations in the presenilin 1 gene on chromosome 14. A presenilin 2 gene has been discovered on chromosome 1, but this defect accounts for less than 1% of cases. The more typical "late onset" cases of AD occurring after age 60 may have underlying genetic defects. A genetic locus on chromosome 19 encodes for a cholesterol transporter called apolipoprotein E (apoE). The E4 variant of apoE, which increases deposition of fibrillar beta-amyloid, can be found in 40% of AD cases. However, the presence of apoE4 is neither necessary nor sufficient for development of AD, so testing for it is not warranted. A genetic locus on chromosome 12 that encodes for alpha-2-macroglobulin may be found in 30% of AD cases. Mutations in the tau gene which codes for

53. Mad Cow Disease: Hundreds Of Articles On Mad Cow Disease, Creutzfeldt-Jakob Dise mad deer disease , scrapie, creutzfeldtjakob disease (CJD and nvCJD), kuru, Mad cow disease creutzfeldt-jakob disease Mad Deer disease, prions, http://www.organicconsumers.org/madcow.htm

O rganic C onsumers A ssociation News About OCA Action Join/Subscribe ... Irradiation Mad Cow Mad Deer Fair Trade Bovine Growth Hormone-rBGH Globalization ... Organic View MEDIA INQUIRIES For media inquiries on the current Mad Cow Crisis in the US,contact: Ronnie Cummins, National Director, Organic Consumers Association: 218-226-4164 or Dr. Michael Greger M.D. Mad Cow Disease Mad Deer Disease Chronic Wasting Disease, Bovine Spongiform Encephalopathy OCA's Mad Cow Menu: USA / Canada / European News Highlighted News CJD Glossary ... Links - Archives: MAD COW / MAD DEER FEATURE ARTICLES Articles reviewed/commented upon by Michael Greger, MD Statement of John Stauber Regarding Impact of Mad Cow Court Decision U.S. Continues to Violate WHO Guidelines for Mad Cow Disease Could Mad Cow Disease Already be Killing Thousands of Americans Every Year? ... American Beef Industry Places Public at Risk (audio) Mad Cow Disease: Plague of the 21st Century?

54. BBC - Health - Conditions - Creutzfeldt-Jakob Disease creutzfeldtjakob disease (CJD). Dr Trisha Macnair. CJD hit the headlines because of the The National creutzfeldt-jakob disease Surveillance Unit http://www.bbc.co.uk/health/conditions/cjd1.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index FRIDAY 9th September 2005 Text only BBC Homepage Lifestyle Health ... Help Like this page? Send it to a friend! Creutzfeldt-Jakob Disease (CJD) Dr Trisha Macnair CJD hit the headlines because of the appearance of a new variant of CJD in young people that may be linked with cattle infected with Bovine Spongiform Encephalitis (BSE). In this article What is it? Symptoms Who's affected? Treatments CJD may have been passed to humans through infected beef products CJD may have been passed to humans through infected beef products because of the link between cattle infected with BSE and a new variant of the disease, vCJD, in young people. But there are several types of CJD and infection isn't the only clue to this mysterious condition - it's not entirely clear how, but cases of CJD may be of an inherited, infectious or unknown origin. About 85 per cent of CJD is sporadic, with no obvious cause - it can't be explained by anything other than random chance. What is it? CJD is a prion disease. Prions are infectious disease-causing agents that consist of a modified protein (unlike bacteria, for example, which are more complex whole cells). In some unique way, which isn't understand, prion proteins can cause degenerative diseases of the nervous tissues (for example, brain, spinal cord and nerves), which are usually fatal.

55. Texas Department Of State Health Services, IDEAS > Creutzfeldt Jakob Disease creutzfeldtjakob disease. creutzfeldt-jakob disease (CJD) is a brain disorder that usually occurs in people over the age of 60. http://www.tdh.state.tx.us/ideas/creutzfeldt-jakob/faqs/

Click Here for Requested Information and Page Content Diseases: A-C Amebiasis Anthrax Arboviral Encephalitides ... Sitemap/Alphabetical Listing of Diseases and Topics Your Location: IDEAS Home Creutzfeldt-Jakob Disease (CJD) Creutzfeldt-Jakob Disease (CJD) ICD-9 046.1, ICD-10 A81.0 FAQs Data Reporting Other Sites What is CJD? What Are CJD's Signs And Symptoms? What Causes CJD? How Do You Get CJD? The first likely case of vCJD was identified in the United States in Florida in April 2002. This person is a 22-year-old United Kingdom (UK) citizen residing in the United States. Investigators concluded that the disease was contracted in the UK (Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, October 18, 2002). The first case of BSE in the United States was identified in an adult Holstein cow from Washington state on December 23, 2003. Preliminary reports suggest that the BSE-infected cow was imported into the United States from Canada in August 2001. The investigation of this case is in progress (Centers for Disease Control and Prevention, Division of Viral and Rickettsial Diseases). Last Updated: Wednesday, September 01, 2004

56. Alzheimer Disease: Related Dementias, Creutzfeldt-Jakob Disease, CJD Alzheimer disease what it is, warning signs, diagnosis and causes. The latest information from the Alzheimer Society of Canada. http://www.alzheimer.ca/english/disease/dementias-creutzfeldt.htm

In this section: Introduction Creutzfeldt-Jakob Disease Lewy body Dementia Frontotemporal Dementia ... Vascular Dementia Related page: What Is Alzheimer Disease? Creutzfeldt-Jakob Disease [Note: If you plan to print this page, please also print the introduction page to Related Dementias. It provides an overview of dementias related to Alzheimer Disease.] What is Creutzfeldt-Jakob Disease? Creutzfeldt-Jakob Disease (CJD) is a rare form of progressive dementia characterized by degeneration and loss of nerve cells leading to the production of microscopic holes in the brain. How does Creutzfeldt-Jakob Disease affect the person? CJD usually has rapid onset and decline. Early symptoms may include lapses in memory, mood swings similar to depression, lack of interest and social withdrawal. The person may become unsteady on her feet. Later symptoms may include blurred vision, sudden jerking movements and rigidity in the limbs. The person may experience slurred speech and have difficulty swallowing. Eventually, movement and speech are lost.

57. Creutzfeldt-Jakob Disease creutzfeldtjakob disease (CJD) is a transmissible, rapidly progressing, creutzfeldt-jakob disease Foundation. PO Box 611625, North Miami, http://www.healthatoz.com/healthatoz/Atoz/ency/creutzfeldt-jakob_disease.jsp

58. CRUETZFEDLT-JAKOB DISEASE creutzfeldtjakob disease (CJD) is a rare, fatal brain disorder caused by a An estimated 200 Americans die each year with creutzfeldt-jakob disease. http://www.idph.state.il.us/public/hb/hbcjdhlb.htm

CREUTZFELDT-JAKOB DISEASE What is Creutzfeldt-Jakob disease? Creutzfeldt-Jakob disease (CJD) is a rare, fatal brain disorder caused by a prion. The disease causes mental deterioration and a variety of neurological symptoms, and usually leads to death within a year of onset. Threre are various forms of CJD; in about 85 percent of the cases, the cause is unknown. One form of CJD may be linked to consumption of beef in Great Britain. Another form is familial or genetic, that is, relatives of a CJD case with the form are more likely to develop the disease than other persons. Many Americans first heard of the disease in 1983 when they learned it had claimed the life of New York City Ballet choreographer George Balanchine. How does CJD affect the patient? In early stages of the disease, patients may experience failing memory, changes in behavior, lack of coordination or visual disturbances. As the illness progresses, mental deterioration becomes pronounced, involuntary movements (especially muscle jerks) appear, and the patient may become blind, develop weakness in the arms or legs, and ultimately lapse into a coma. Death is usually due to infections in the bedridden, unconscious patient. Symptoms of CJD can be similar to those seen in other progressive neurological disorders such as Alzheimer's disease and other dementias. However, CJD causes unique changes in brain tissue that, at this time, can be detected only by surgical biopsy or at autopsy.

59. Introduction: Creutzfeldt-Jakob Disease - WrongDiagnosis.com Introduction to creutzfeldtjakob disease as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis. http://www.wrongdiagnosis.com/c/creutzfeldt_jakob_disease/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Creutzfeldt-Jakob Disease Next sections Basic Summary for Creutzfeldt-Jakob Disease Prevalence and Incidence of Creutzfeldt-Jakob Disease Prognosis of Creutzfeldt-Jakob Disease Types of Creutzfeldt-Jakob Disease ... Causes of Creutzfeldt-Jakob Disease Next chapters: Variant CJD Kuru Fatal familial insomnia Feline spongiform encephalopathy ... Feedback Introduction: Creutzfeldt-Jakob Disease Creutzfeldt-Jakob Disease: Creutzfeldt-Jakob Disease (CJD) is a rare 1-in-a-million disease that occurs spontaneously, with 10-15% inheritance, and unrelated to animal diseases. It usually leads to dementia. CJD is a rare brain disease in humans caused by abnormal brain proteins ( prions ). It is similar to the various transmissible spongiform encephalopathies that afflict animals including " mad cow disease ". Unfortunately, prognosis for CJD is poor as there are no effective treatments against prions. CJD is not usually contagious, except rarely by direct exposure to the brain (such as brain surgery). Because CJD is rare it is often misdiagnosed as other brain-related diseases. Common misdiagnoses include

60. Article: Creutzfeldt-Jakob Disease Fact Sheet: NINDS - WrongDiagnosis.com Medical article creutzfeldtjakob disease Fact Sheet NINDS including all symptom, diagnosis, misdiagnosis, treatment and prevention information. http://www.wrongdiagnosis.com/artic/creutzfeldt_jakob_disease_fact_sheet_ninds.h

Home Symptoms Diseases Risks ... Newsletter Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Creutzfeldt-Jakob Disease Fact Sheet: NINDS Next chapters: Crime and Older People - Age Page - Health Information: NIA Crohn's Disease: NIDDK Cryptococcal Meningitis, NIAID Fact Sheet: NIAID Cryptococcosis: DBMD ... Feedback Creutzfeldt-Jakob Disease Fact Sheet: NINDS Article title: Creutzfeldt-Jakob Disease Fact Sheet: NINDS Main condition: CJD Conditions: CJD Table of Contents What is Creutzfeldt-Jakob Disease? What are the Symptoms of the Disease? How is CJD Diagnosed? How is the Disease Treated? ... Where Can I Get Help? What is Creutzfeldt-Jakob Disease? Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. It affects about one person in every one million people per year worldwide; in the United States there are about 200 cases per year. CJD usually appears in later life and runs a rapid course. Typically, onset of symptoms occurs about age 60, and about 90 percent of patients die within 1 year. In the early stages of disease, patients may have failing memory, behavioral changes, lack of coordination and visual disturbances. As the illness progresses, mental deterioration becomes pronounced and involuntary movements, blindness, weakness of extremities, and coma may occur.

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