21. Facial Nerve congenital facial diplegia; ± Asymmetric; Ophthalmoplegia, esp VI nerve;Mental retardation; ± Peripheral neuropathy; Skeletal Arthrogryposis; http://www.neuro.wustl.edu/neuromuscular/nanatomy/vii.htm

Front Search Index Links ... Patient Info FACIAL NERVE (VII) DISORDERS Anatomy Bell's palsy Differential diagnosis Facial nerve: Anatomy 2 roots Motor from facial nucleus Nervus intermedius Preganglionic parasympathetics (from superior salivatory nucleus) Branches Nerve to stapedius muscle Chorda tympani: Taste Sensory auricular branch Some axons may arise from vagus (Arnold's nerve) Motor: Facial muscles Facial nerve: Anatomical Diagram External link Brainstem anatomy Nerve anatomy: USUHS Yale Facial nerve paralysis: Signs Facial asymmetry Eyebrow droop Drooping of corner of mouth Uncontrolled tearing Inability to close eye Lips cannot be held tightly together: Diificulty keeping food in mouth Facial muscle atrophy (Late) Facial Paresis: Left Bell's Palsy Sir Charles Bell Epidemiology Lifetime prevalence: 6.4 to 20 per 1,000 Incidence: Increased with age Overall: 0.5 per year per 1,000 Age 20: 0.1 per year per 1,000 Age 80: 0.6 per year per 1,000 Male = Female Recurrence: 7% Side: Right in 63% Increased incidence: Diabetes; Pregnant females Pathogenesis Evidence for herpes simplex type 1 infection Clinical Features Onset Paralysis: Progresses to maximal defecit over 3 to 72 hours Pain (50%): Near mastoid process Excess tearing (33%) Other: Hyperacusis; Dysgeusia

22. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Genetic_Disorders/ Mobius Syndrome Also known as congenital facial diplegia, an information sheetcompiled by NINDS. MCW Healthlink Mobius Syndrome - Details about this http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Genetic_Dis

@import "/styles/navbar.css"; @import "/styles/tabStyles.css"; Set home page Bookmark site Add search Latest News ... Email to friend Text Size A A A Front Page ... Genetic Disorders : Mobius Syndrome Subtopics Search Google: Mobius Syndrome News Books Links ... Mayo Clinic Develops New Coma Measurement System (September 8, 2005) full story Nitric Oxide Could Extend Fertility (September 8, 2005) Biochemistry , an American Chemical Society journal. full story Flipped, Expelled, Copied, And Shrunk: Researchers Document Dramatic Genome Alterations During Primate Evolution (September 6, 2005) Genome Research presents a series of studies that provide insight into the evolution and variation of primate genomes. The issue will appear online and in print on September 1, concomitant with the publication of the chimpanzee genome sequence in the journal Nature full story Discovery Will Aid Identification Of Misregulated Genes In Rett Syndrome (September 4, 2005) Molecular Cell that the "Rett Syndrome protein", MeCP2, only binds to genes with a specific sequence of nucleotide bases. This knowledge will aid in the identification of the genes that are regulated by the gene MECP2. This work was supported, in part, by the Rett Syndrome Research Foundation (RSRF). full story Big Differences In Duplicated DNA Distinguish Chimp And Human Genomes (September 2, 2005)

23. ScienceDaily -- Browse Topics: Health/Child_Health/Conditions_and_Diseases/Conge congenital facial diplegia Congenital Heart Disease Congenital MusculoskeletalDisorders Congenital Nephroblastoma Congenital Pain Insensitivity http://www.sciencedaily.com/directory/Health/Child_Health/Conditions_and_Disease

@import "/styles/navbar.css"; @import "/styles/tabStyles.css"; Set home page Bookmark site Add search Latest News ... Email to friend Text Size A A A Front Page ... Conditions and Diseases : Congenital Disorders Subtopics Congenital Facial Diplegia Congenital Heart Disease Congenital Musculoskeletal Disorders Congenital Nephroblastoma ... Genetic Disorders See Also: Health: Conditions and Diseases: Congenital Anomalies Search Google: Congenital Disorders News Books Links ... Detecting Brain Infections Without Surgery (September 7, 2005) full story Marijuana-derived Drug Suppresses Bladder Overactivity And Irritation In Animal Models (September 6, 2005) full story A New Player In The Battle Against Hepatitis Prevents Inflammation And The Death Of Liver Cells (September 5, 2005) full story Pinpointing The Cause Of A Neurodegenerative Disorder (August 30, 2005) full story Gender Hormones May Lend To Social Disorder Therapies (August 29, 2005) full story Scientists Listen To Brain Patterns Of Tone-deafness (August 29, 2005) full story Neurotransmitter Orexin Associated With Pleasure And Reward Pathways In The Brain (August 28, 2005) full story Researchers Find Evidence For 'Tanning Addiction' (August 27, 2005)

24. %601471 FACIAL PARESIS, HEREDITARY, CONGENITAL; HCFP1 (1967) observed congenital facial diplegia in 3 generations of a family.Masaki (1971) reported father and a son and daughter with bilateral facial http://srs.sanger.ac.uk/srsbin/cgi-bin/wgetz?[omim-ID:601471] -e

25. %157900 MOEBIUS SYNDROME; MBS (1977) observed congenital facial diplegia and flexion finger contractures in 7members of 3 Neuro, congenital facial diplegia; Cranial nerve VI palsy; http://srs.sanger.ac.uk/srsbin/cgi-bin/wgetz?[omim-ID:157900] -e

26. Neurology -- Sign In Page congenital facial diplegia due to nuclear lesion. Rev Neurol Psychiatry 1903;1149–155 . The spectrum of congenital facial diplegia (Möbius syndrome). http://www.neurology.org/cgi/content/full/64/4/649

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This item requires a subscription to Neurology Online. Full Text Verzijl et al. Neurology. This Article Abstract Figures Only Full Text (PDF) ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Verzijl, H. T.F.M. Articles by Padberg, G. W. Related Collections Cranial neuropathy Anterior nerve cell disease To view this item, select one of the options below: Sign In User Name Sign in without cookies. Can't get past this page? Help with Cookies. Need to Activate? Password Forgot your user name or password? Purchase Short-Term Access Pay per Article - You may access this article (from the computer you are currently using) for 1 day for US$20.00 Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.

27. Neuroguide.com - Human Neurological Diseases congenital facial diplegia. * Mobius Syndrome Information (NINDS) CongenitalFacial Diplegia, Corticobasal Degeneration, Cranial Arteritis http://www.neuroguide.com/cgi-bin/pdistoc.pl?file=CongenitalFacialDiplegia

28. Neuroguide.com - Human Neurological Diseases Unexplained Facial Pain Medical resources for the treatment of Trigeminal congenital facial diplegia, Corticobasal Degeneration, Cranial Arteritis http://www.neuroguide.com/cgi-bin/pdistoc.pl?file=trigeminal

29. Moebius Syndroom Moebius syndroom. Synoniemen congenital facial diplegia Congenital OculofacialParalysis Moebieus Sequence. Korte beschrijving http://www.erfelijkheid.nl/zena/moebi.php

A B C D ... OVERIG Moebius syndroom Synoniemen Congenital Facial Diplegia Congenital Oculofacial Paralysis Moebieus Sequence Korte beschrijving Het Moebius syndroom is een aangeboren aandoening. Het wordt gekenmerkt door een uitdrukkingsloos gezicht. Twee van de twaalf hoofdzenuwen werken niet goed, namelijk de zenuwen die de oogbewegingen en gezichtsexpressie besturen. Vaak werken ook andere zenuwen niet helemaal goed. Er zijn nog andere symptomen die bij het Moebius Syndroom kunnen voorkomen, zoals: kaakvervormingen, afwijkingen aan de tong, slikproblemen, scheelkijken, klompvoeten en handafwijkingen. Soms gaat Moebius samen met een verstandelijke beperking of, in een enkel geval, autisme. Moebius gaat soms samen met de Pierre Robin sequentie Diagnose Het Moebius syndroom kan worden vermoed op grond van bovenstaande verschijnselen. Maar omdat het zeer weinig voorkomt, wordt het niet altijd herkend. Behandeling Het Moebius syndroom is niet te genezen. De gelaatsuitdrukking kan door plastische chirurgie verbeterd worden. Ook kunnen aandoeningen aan de ledematen en scheel kijken gecorrigeerd worden. Fysiotherapie kan helpen bij het ontwikkelen van de gezichtsmotoriek. Voorkomen (frequentie) In Nederland worden ongeveer 4 à 5 kinderen per jaar met het Moebius syndroom geboren.

30. Mobius Syndrome . This book has been created for......congenital facial diplegia Syndrome; Congenital Oculofacial Paralysis; MobiusSyndrome; Moebieus Sequence. http://www.icongrouponline.com/health/Mobius_Syndrome.html

ICON Health Publications Official Health Sourcebooks Search ICON Health Titles: The Official Parent's Sourcebook on MOBIUS SYNDROME (Congenital Facial Diplegia Syndrome; Congenital Oculofacial Paralysis; Mobius Syndrome; Moebieus Sequence) Revised and Updated for the Internet Age P A P E R B A C K Paperback Book Shipped in 3 to 5 business days E B O O K Electronic File * E-Book version sent via e-mail in 2 business days Pages Price $28.95(USD) ISBN Published Synopsis A comprehensive manual for anyone interested in self-directed research on . Fully referenced with ample Internet listings and glossary. Related Conditions/Synonyms Congenital Facial Diplegia Syndrome; Congenital Oculofacial Paralysis; Mobius Syndrome; Moebieus Sequence Description Table of Contents Introduction Overview Organization Scope Moving Forward PART I: THE ESSENTIALS Chapter 1. The Essentials on Mobius Syndrome: Guidelines Overview What Is Mobius Syndrome? Is There Any Treatment? What Is the Prognosis? What Research Is Being Done? Selected References For More Information More Guideline Sources Vocabulary Builder Chapter 2. Seeking Guidance

31. Health/Conditions And Diseases/Genetic Disorders/Mobius Syndrome -- The Doctors Also known as congenital facial diplegia, an information sheet compiled by NINDS.url www.ninds.nih.gov/health_and_medical/disorders/mob. http://www.thedoctorslounge.net/dir/Health/Conditions_and_Diseases/Genetic_Disor

Advertisement Powered by Careerbuilder Search for: Home Humor Advertising Contact ... Links Specialties Cardiology Chest diseases Dermatology Endocrinology ... Urology Other Sections Membership Research Tools Medical Tutorials Medical Software ... Specialized Centers Headlines: The Medical Website Directory Popular Categories Popular Links Web Sites report abuse/spam url: report-abuse.dmoz.org/?cat=Health/Conditions_and_D... About.com with Laura L. Jelliffe, Ph.D. Symptoms, diagnosis, and treatment of mobius syndrome. Information on research, community outreach and support. url: genetics.about.com/science/genetics/library/blmob.... MCW Healthlink: Mobius Syndrome Details about this disease, including what it is, the causes, symptoms and treatment options. url: healthlink.mcw.edu/article/921441372.html Mobius Syndrome Also known as congenital facial diplegia, an information sheet compiled by NINDS. url: www.ninds.nih.gov/health_and_medical/disorders/mob... Moebius Syndrome Foundation Bringing together information from and links to medical and lay support for those affected by Moebius syndrome. url: www.ciaccess.com/moebius/

32. The Laryngoscope - UserLogin Although unlikely, an incomplete congenital facial diplegia could conceivably bemissed The spectrum of congenital facial diplegia (Moebius syndrome). http://www.laryngoscope.com/pt/re/laryngoscope/fulltext.00005537-199804000-00011

LWWOnline LOGIN eALERTS REGISTER ... Publish Ahead of Print You are attempting to access protected content. To access this content please login using an established account or create/activate an account. If you have already created/ activated an online account, please login below: User Name: Password: Note: passwords are CASE SENSITIVE If you are a new user or guest visiting an LWWonline site for the first time, please complete the new account setup process to view or purchase content. Forgot your password? Subscribe Renewal Information Subscribe to RSS feed utrdc-pt02 Release 4.0

33. Mobius Syndrome Mobius syndrome, congenital facial diplegia with restriction of lateral eyemovements, was first described by von Graefe in 1880 (von Graefe 1880). http://www.medlink.com/PublicCIP.ASP?access=public&UID=MLT000HD&code=

34. Mobius Syndrome Synonym(s) congenital facial diplegia. What is Mobius Syndrome? Mobius syndrome,a rare genetic disorder characterized by facial paralysis, http://www.clevelandclinic.org/health/health-info/docs/1300/1307.asp?index=6064&

35. Journal Of Craniofacial Surgery - UserLogin Henderson J. The congenital facial diplegia syndrome clinical features, pathologyand Engler R, Oetgen W, Hyman L. congenital facial diplegia (Moebius http://www.jcraniofacialsurgery.com/pt/re/jcransurg/fulltext.00001665-200309000-

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36. Entrez PubMed A 13year-old boy with autosomal-dominant congenital facial diplegia was evaluatedby electrophysiol http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2

37. Entrez PubMed Pathogenetic considerations on congenital facial diplegia Article in ItalianDi Tizio A, D Ambrosi D. MeSH Terms Abducens Nerve/abnormalities* http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=5

38. Möbius' Syndrome II (www.whonamedit.com) Akinesia algera; arthrogryposis; congenital abducensfacial paralysis; congenitalbulbar paralysis; congenital facial diplegia; congenital facial paralysis; http://www.whonamedit.com/synd.cfm/52.html

Home List categories Eponyms A-Z Biographies by country ... Contact Whonamedit.com does not give medical advice. This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor. A recommendation: Hypography is an open community about science and all things related Möbius' syndrome II Also known as: Möbius anomalad Synonyms: Akinesia algera; arthrogryposis; congenital abducens-facial paralysis; congenital bulbar paralysis; congenital facial diplegia; congenital facial paralysis; congenital nuclear agenesis; congenital nuclear aplasia; congenital occulofacial paralysis; congenital paralysis of the sixth and seventh nerves; infantile nuclear aplasia; nuclear agenesis syndrome; oculofacial paralysis syndrome; Associated persons: Paul Julius Möbius Description: In this very rare syndrome, the abducens and facial nerves, which originate in the brain stem, may not develop from birth. It is characterized by congenital palsy of the external rectus and facial muscles, usually bilateral, associated with paralysis of the sixth and seventh nerves. The patient has a masklike expression and is unable to abduct the eyes beyond midpoint. Involvement of the jaw may cause feeding problems.

39. Leslie med8589 327 The spectrum of congenital facial diplegia (Moebius syndrome).med75-79 327 Moebius syndrome. med93-95 326 Congenital syndromes of oculomotor http://neuro-www.mgh.harvard.edu/neurowebforum/ChildNeurologyArticles/Leslie.htm

Leslie This response submitted by Dr. Shawn K. Centers on 12/19/96. Author's Email: Dear Leslie: Although previuosly it was thought that there was an agenesis ( failure to develop )of the control centers for the cranial nerves ( especially cranial nerve VI and VII) some of the recent research seems to call this into question. If there is complete agenesis this means that there is no possibility of the facial paralysis improving or worsening. One recent report describes muscle recruitment measured by EMG studies in two Moebius patients following treatment with simple physical therapy. In another report there is described improvement in facial paralysis using biofeedback techniques (the patients were both children). The Miami Project in FL seems to be the center that is doing the most research with biofeedback training in muscle paralysis. There is also a research center in England who claims to have gotten improvement in muscle hypotonia and facial paralysis using a type of tactile kinesthetic stimulation using "brushing technique" wirth a number of Moebius patients (mostly children). As of yet their research is unpublished. There are likewise reports of a Moebius patient's paralysis worsening and thought to be caused by a superimposed Bell's Palsy. When I was younger I recieved treatment at the Michigan State University We really have very little to offer them at this time in terms of treatment. With better information we may be able to offer some suggestions

40. Mobius Syndrome Topic - Unified Search Environment CONGENITAL NUCLEAR APLASIA DXP/SY/NOCODE congenital facial diplegia SYNDROMEDXP/SY/NOCODE PARALYSIS, OCULOFACIAL, CONGENITAL DXP/SY/NOCODE http://www.use.hcn.com.au/portals/shared/subject.`Mobius Syndrome`/home.html

Mobius Syndrome Topic Tree Definition: A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020) Synonyms and Source Vocabularies: Mobius Syndrome CONGENITAL NUCLEAR APLASIA CONGENITAL FACIAL DIPLEGIA SYNDROME PARALYSIS, OCULOFACIAL, CONGENITAL Moebius Congenital Oculofacial Paralysis Hypoglossia-hypodactyly syndrome Congenital Abnormality Abnormalities, Drug-Induced Abnormalities, Multiple Basal Cell Nevus Syndrome Beckwith-Wiedemann Syndrome Bloom Syndrome Cockayne Syndrome ... Congenital neurologic anomalies

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