1. Mobius Syndrome Information Page: National Institute Of Neurological Disorders A Mobius Syndrome (congenital facial diplegia) information sheet compiled by theNational Institute of Neurological Disorders and Stroke (NINDS). http://www.ninds.nih.gov/disorders/mobius/mobius.htm

Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system More about Mobius Syndrome Studies with patients Research literature Press releases Search NINDS... (help) Contact Us My Privacy NINDS is part of the National Institutes of Health You are here: Home Disorders Mobius Syndrome NINDS Mobius Syndrome Information Page Synonym(s): Congenital Facial Diplegia Get Web page suited for printing Email this to a friend or colleague Table of Contents (click to jump to sections) What is Mobius Syndrome? Is there any treatment? What is the prognosis? What research is being done? ... Organizations What is Mobius Syndrome? Is there any treatment? There is no specific course of treatment for Mobius syndrome. Treatment is supportive and in accordance with symptoms. Infants may require feeding tubes or special bottles to maintain sufficient nutrition. Surgery may correct crossed eyes and improve limb and jaw deformities. Physical and speech therapy often improves motor skills and coordination, and leads to better control of speaking and eating abilities. Plastic reconstructive surgery may be beneficial in some individuals. Nerve and muscle transfers to the corners of the mouth have been performed to provide limited ability to smile. What is the prognosis?

2. NINDS Forwarding Page Also known as congenital facial diplegia, an information sheet compiled by NINDS. http://www.ninds.nih.gov/health_and_medical/disorders/mobius.htm

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3. Mobius Syndrome Information Page National Institute Of Mobius Syndrome (congenital facial diplegia) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. Disorders Index: National Institute Of Neurological Disorders And Stroke (NINDS) congenital facial diplegia Congenital Myasthenia Congenital Myopathy Congenital Vascular Cavernous Malformations Corticobasal Degeneration http://www.ninds.nih.gov/disorders/disorder_index.htm

Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system Browse All Disorders Browse All Organizations More about a disorder Clinical Trials Research Literature Press Releases Search NINDS... (help) Contact Us My Privacy NINDS is part of the National Institutes of Health You are here: Home Disorders Features Stroke: What You Need to Know Curriculum Supplement Browse All Disorders (includes synonyms and research topics) Request mailed brochures Select a letter to jump to the disorder or return to top of page A B C D ... Z A Absence of the Septum Pellucidum Acquired Epileptiform Aphasia Acute Disseminated Encephalomyelitis ADHD ... Autonomic Dysfunction Select a letter to jump to the disorder or return to top of page A B C D ... Z B Back Pain Barth Syndrome Batten Disease Behcet's Disease ... Bulbospinal Muscular Atrophy Select a letter to jump to the disorder or return to top of page A B C D ... Z C Canavan Disease Carpal Tunnel Syndrome Causalgia Cavernomas ... Cytomegalovirus Infection Select a letter to jump to the disorder or return to top of page A B C D ... Z D Dancing Eyes-Dancing Feet Syndrome Dandy-Walker Syndrome Dawson Disease De Morsier's Syndrome ... Dystonias Select a letter to jump to the disorder or return to top of page A B C D ... Z E Early Infantile Epileptic Encephalopathy Empty Sella Syndrome Encephalitis Lethargica Encephaloceles ... Erb's Palsy Select a letter to jump to the disorder or return to top of page A B C D ... Z F Fabry's Disease Fahr's Syndrome Fainting Familial Dysautonomia ... Friedreich's Ataxia Select a letter to jump to the disorder or return to

5. Moebius Syndrome (Congenital Facial Diplegia) Moebius Syndrome/Sequence (congenital facial diplegia) Moebius Support. MOEBIUS SEQUENCE/SYNDROME. MOEBIUS SYNDROME SUPPORT NETWORK http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. Medical Dictionary: Congenital Facial Diplegia - WrongDiagnosis.com Medical dictionary definition of congenital facial diplegia as a medical termincluding diseases, symptoms, treatments, and other medical and health issues. http://www.wrongdiagnosis.com/medical/congenital_facial_diplegia.htm

Home Symptoms Diseases Risks ... Dictionary Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Congenital Facial Diplegia Next chapters: Congenital heart conditions Congenital immunodeficiency Congenital nephroblastoma Congenital Spinal Muscular Atrophy with arthrogryposis ... Feedback Medical Dictionary: Congenital Facial Diplegia Medical dictionaries: Medical dictionary Medical malpractice dictionary Medical Acronymns/Abbreviations Congenital Facial Diplegia : Another name for Mobius syndrome (or close medical condition association). Congenital Facial Diplegia : Congenital Facial Diplegia is listed as a type of (or associated with) the following medical conditions in our database: Congenital conditions Genetic Disease Congenital Facial Diplegia (medical condition): Type of facial paralysis. Congenital Facial Diplegia : Mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or underdevelopment of the 6th and 7th cranial nerves. These nerves control eye movements and facial expression. More information on medical condition: Mobius syndrome Introduction: Mobius syndrome Basic Summary for Mobius syndrome Symptoms of Mobius syndrome Treatments for Mobius syndrome Footnotes: 1. excerpt from

7. MOEBIUS SYNDROME (CONGENITAL FACIAL DIPLEGIA) Features Listed For MOEBIUS SYNDROME (congenital facial diplegia) McKusick 157900. Absent fingers or oligodactyly http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Medical Dictionary: Congenital CMV Infection - WrongDiagnosis.com Print this document Previous Home Up Congenital CMV infection NextChapter 5689 Medical Dictionary congenital facial diplegia http://www.wrongdiagnosis.com/medical/congenital_cmv_infection.htm

Home Symptoms Diseases Risks ... Dictionary Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Congenital CMV infection Next chapters: Congenital Facial Diplegia Congenital heart conditions Congenital immunodeficiency Congenital nephroblastoma ... Feedback Medical Dictionary: Congenital CMV infection Medical dictionaries: Medical dictionary Medical malpractice dictionary Medical Acronymns/Abbreviations Congenital CMV infection : Another name for Infant Cytomegalic virus (or close medical condition association). Congenital CMV infection : Congenital CMV infection is listed as a type of (or associated with) the following medical conditions in our database: Cytomegalovirus Viral diseases Congenital CMV infection (medical condition): A serious CMV viral infection in newborns. Congenital CMV infection : CMV is the leading cause of congenital infection in the United States. An estimated 6,000 babies each year develop life-threatening complications of congenital CMV infection at birth or suffer serious consequences later in life, including mental retardation, blindness, deafness, or epilepsy. Investigators supported by NIAID are currently studying how the virus interferes with normal fetal development and at which stages the fetus is most susceptible to infection. Congenital CMV is the most common cause of progressive deafness in children.

9. Medical Dictionary Congenital Facial Diplegia - WrongDiagnosis.com Medical dictionary definition of congenital facial diplegia as a medical term including diseases, symptoms, treatments, and other medical and health http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. Mobius Syndrome Information Page National Institute Of Neurological Mobius Syndrome (congenital facial diplegia) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. EMedicine - Möbius Syndrome : Article Excerpt By: Cheryl Ann Palmer, MD Although von Graefe described a case of congenital facial diplegia in 1880, thesyndrome was reviewed and defined further by Möbius in 1888 and 1892. http://www.emedicine.com/neuro/byname/möbius-syndrome.htm

(advertisement) Excerpt from Möbius Syndrome Synonyms, Key Words, and Related Terms: congenital facial diplegia, congenital nuclear agenesis, congenital nuclear hypoplasia, congenital oculofacial paralysis Please click here to view the full topic text: Möbius Syndrome Background: Möbius syndrome is due, in part, to loss of function of motor cranial nerves. Although von Graefe described a case of congenital facial diplegia in 1880, the syndrome was reviewed and defined further by Möbius in 1888 and 1892. Because of these contributions, Möbius is now the eponym used to describe the syndrome. The definition and diagnostic criteria for Möbius syndrome vary among authors. Both von Graefe and Möbius accepted only cases with both congenital facial diplegia and bilateral abducens nerve palsies as constituting Möbius syndrome. In 1939, Henderson broadened the definition and included cases with congenital unilateral facial palsy. Other authors are more restrictive in attempts to eliminate conditions of a different pathogenesis being labeled as Möbius syndrome. These investigators require the presence of a congenital musculoskeletal anomaly in order to make the diagnosis. Pathophysiology: The complete pathophysiological description of Möbius syndrome remains elusive. Whether nerve, brainstem, or muscle aplasia is the primary event has not been established. Nerves that may be involved include cranial nerves (CN) VI through XII, with general sparing of CN VIII. CN III and CN IV can be involved, but rarely are. The facial nerves (CN VII) are involved in all cases, the abducens nerves (CN VI) in a high percentage of cases (75%), and the hypoglossal nerves (CN XII) in only a minority of cases.

12. Dorlands Medical Dictionary facial diplegia, congenital, M bius syndrome. F rster's diplegia, atonicastatic d. infantile diplegia, birth palsy. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Moebius Syndrome congenital facial diplegia Syndrome; Congenital Oculofacial Paralysis; Mobius Syndrome;Moebieus Sequence. Disorder Subdivisions. None. General Discussion http://my.webmd.com/hw/raising_a_family/nord451.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report Moebius Syndrome Important It is possible that the main title of the report Moebius Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Congenital Facial Diplegia Syndrome Congenital Oculofacial Paralysis Mobius Syndrome Moebius Sequence Disorder Subdivisions None General Discussion Moebius syndrome is a rare developmental disorder present at birth (congenital) that is characterized by facial paralysis. Affected individuals are not able to smile or frown because two important nerves, the sixth (abducens) and seventh (facialis) cranial nerves are absent or not fully developed. In some instances, this syndrome may also be associated with physical problems in other parts of the body. Resources Children's Craniofacial Association 13140 Coit Road Suite 307 Dallas, TX 75240

14. Congenital Facial Diplegia - Topic , congenital facial diplegia, http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Moebius Syndrome Synonyms. congenital facial diplegia Syndrome; Congenital Oculofacial Paralysis;Mobius Syndrome; Moebieus Sequence. Disorder Subdivisions. None http://www.bchealthguide.org/kbase/nord/nord451.htm

var hwPrint=1;var hwDocHWID="nord451";var hwDocTitle="Moebius Syndrome";var hwRank="1";var hwSectionHWID="nord451-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Moebius Syndrome Important It is possible that the main title of the report Moebius Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Congenital Facial Diplegia Syndrome Congenital Oculofacial Paralysis Mobius Syndrome Moebieus Sequence Disorder Subdivisions None General Discussion Moebius syndrome is a rare developmental disorder present at birth (congenital) that is characterized by facial paralysis. Affected individuals are not able to smile or frown because two important nerves, the sixth (abducens) and seventh (facialis) cranial nerves are absent or not fully developed. In some instances, this syndrome may also be associated with physical problems in other parts of the body. Resources Children's Craniofacial Association 13140 Coit Road Suite 307 Dallas, TX 75240

16. Webkatalog 3. Mobius Syndrome Also known as congenital facial diplegia, an information sheet compiled by NINDS. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Moebius Syndrome (Congenital Facial Diplegia) Moebius Syndrome/Sequence (congenital facial diplegia). Moebius Support MOEBIUS SEQUENCE/SYNDROME MOEBIUS SYNDROME SUPPORT NETWORK Mobius Syndrome http://www.bdid.com/moebius.htm

HOME Moebius Syndrome/Sequence (Congenital Facial Diplegia) Moebius Support MOEBIUS SEQUENCE/SYNDROME MOEBIUS SYNDROME SUPPORT NETWORK Mobius Syndrome ... HOME

18. Congenital Facial Diplegia Web resources on congenital facial diplegia. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. Birth Disorder Information Directory - CO-CZ congenital facial diplegia. List of Sites. Congenital Fiber Type Disproportion.Congenital fiber type disproportion CONGENITAL MUSCLE FIBRETYPE http://www.bdid.com/defectco.htm

HOME Co-Cy COACH Syndrome See Cerebellar Vermis Hypo/Aplasia, Oligophrenia, Congenital Ataxia, Ocular Coloboma, and Hepatic Fibrosis (COACH) Syndrome Coarctation of (the) Aorta (CoA) List of Sites Coats' Disease (Congenital Retinal Telangiectasia, Exudative Retinitis, Leber Miliary Aneurysm) Coats disease Cobb Syndrome Syndromes associated with AVMs Cocaine Antenatal Infection See Fetal Cocaine Syndrome Related Books Cochin Jewish Disorder (Haim Munk Syndrome, Keratosis Palmoplantaris Periodontopathia) Keratosis palmoplantaris periodontopathia KERATOSIS PALMOPLANTARIS WITH PERIODONTOPATHIA AND ONYCHOGRYPOSIS Cockayne Syndrome List of Sites COD-MD Syndrome See Walker Warburg Syndrome CODAS Syndrome (Cerebrooculodentoauriculoskeletal Syndrome) Cerebro oculo dento auriculo skeletal syndrome CODAS SYNDROME Coffin Syndrome (Arthritis Short Stature Deafness) Coffin syndrome Coffin-Lowry Syndrome List of Sites Coffin Siris Syndrome (Fifth Digit Syndrome) Coffin siris syndrome FIFTH DIGIT SYNDROME COFS Syndrome See Cerebrooculofacioskeletal (COFS) Syndrome Cohen Hayden Syndrome (Proteus-Like Syndrome with Mental Retardation and Eye Defects) Cohen hayden syndrome Cohen Lockood Wyborney Syndrome (Blepharophimosis Ptosis Syndactyly Mental Retardation) blepharophimosis ptosis syndactyly mental retardation Cohen Syndrome List of Sites Colavita Kozlowski Syndrome (Short Limb Dwarf, Lethal Colavita Kozlowski Type)

20. Volume 62 January - December 1939 The congenital facial diplegia syndrome clinical features, pathology and aetiology JL . Henderson. Pages 381 403 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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