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  1. Thiamine Deficiency and Associated Clinical Disorders (Contemporary Clinical Neuroscience) by David W. McCandless, 2009-09-15

41. Central Pontine Myelinolysis In A Previously Healthy 4-Year-Old Child With Acute
central pontine myelinolysis (CPM) is rare, with fewer than 30 cases reported inchildren. First described in 1959,3 it is a demyelinating process that
http://pediatrics.aappublications.org/cgi/content/extract/99/5/738
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PEDIATRICS Vol. 99 No. 5 May 1997, pp. 738-742
EXPERIENCE AND REASON:
Central Pontine Myelinolysis in a Previously Healthy 4-Year-Old Child With Acute Rotavirus Gastroenteritis
The first 300 words of the full text of this article appear below. INTRODUCTION Acute gastroenteritis is one of the most common childhood illnesses encountered today. Vomiting and diarrhea often cause dehydration. Although the disease is usually self-limiting, patients may require rehydration therapy. Central pontine myelinolysis (CPM) is rare, with fewer than 30 cases reported in children. First described in 1959, it is a demyelinating process that affects the central pons and may involve other white matter areas. CPM presents with an altered

42. BrainTalk Communities - Central Pontine Myelinolysis...
Online patient support groups for healthcare and neurology.
http://brain.hastypastry.net/forums/archive/index.php/t-52367.html
BrainTalk Communities Specific Neurological Conditions (A - L) Cerebellar Disorders PDA View Full Version : Central Pontine Myelinolysis... WhataBreeze 11-24-2004, 09:52 PM HELLO FRIEND... :)
SINCE THIS FORUM'S LAST THREAD WAS 8/22/04 I THOUGHT I'D GIVE IT A
LITTLE WAKE UP CALL. CPM IS ALSO LISTED AS A CEREBELLAR DISORDER.
YES THERE ARE ONLY A FEW OF US AROUND HERE AT B/T THAT EITHER HAS
THIS KILLER DEMYELINATING MYELIN DISORDER IN THE BRAINSTEM THAT
TAKES 75% OF US WITHIN 30 DAYS OF DX OR MOST OF THE 25% WHO ARE
LUCKY/UNLUCKY ENOUGH TO LIVE ON. WE THAT HAVE CPM FIND IT
SOOOOO AMAZING WHEN WE SIT BACK AND WATCH ALL YOU NICE PEOPLE
TRYING TO HELP ONE ANOTHER. :) THE BEST WE CAN DO IS FIND
ANOTHER "CPM'ER" TO ADD TO OUR LIST TO JUST SUPPORT EACH OTHER
AND TALK ABOUT OUR SYMPTOMS TOGETHER. WE HAVE NO FOUNDATIONS TO EVEN RECOGNIZE IT. EVEN TODAY AS MY FATHER IS IN A TOP NOTCH HOSPITAL IN A MAJOR CITY IN THE U.S. ON A RENAL AND NEUROLOGICAL FLOOR, I HAVE YET TO FIND ANYONE WITHOUT THEIR MD TO KNOW WHAT IT IS. "JOIN US SOMETIME AND READ SOME OF THESE NEW THREADS

43. BrainTalk Communities - Central Pontine Myelinolysis
Online patient support groups for healthcare and neurology.
http://brain.hastypastry.net/forums/archive/index.php/t-38666.html
BrainTalk Communities Specific Neurological Conditions (M - Z) Myelin Disorders PDA View Full Version : central pontine myelinolysis browny 09-15-2004, 02:35 PM Hi,i am a resident of the UK who has been diagnosed with CPM.There seems to be no expertise on this condition in the UK.Any help,advise,or even chat most welcome. WhataBreeze 09-15-2004, 10:40 PM Hello Browny, :cool:
There are a few of us floating around BT as you will see. Our closest cousin will be those in the MS forums. I have found that most don't have a clue what CPM is however most on this site have been very kind and accepting to those of us that unfortunately were totally forgot about mainly because we were dead before they got to us. In time, slowly but surely I'm hoping we might just find enough of us to make a dent in the wonderful world of medicine. Saying my prayers that a real inteligent research MD might pick up on a few of us seeing that we aren't totaled yet. I hope to chat more with you and a few others will come out of the woodwork to say hi. God Bless. :) tragic 09-27-2004, 08:09 PM

44. Parkinsonism And Dystonia In Central Pontine And Extrapontine Myelinolysis -- Se
A 51 year old woman developed central pontine myelinolysis and Central pontinemyelinolysis is a well defined syndrome characterised by various degrees
http://www.jnnp.com/cgi/content/full/65/1/119

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Vol Page [Advanced] This Article Abstract Full Text (PDF) Submit a response ... Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Seiser, A Articles by Brainin, M J Neurol Neurosurg Psychiatry 119-121 ( July )
Short report
Parkinsonism and dystonia in central pontine and extrapontine myelinolysis
A Seiser, a S Schwarz, a M M Aichinger-Steiner, a G Funk, a P Schnider, b M Brainin a a Center for Postgraduate Studies in Neuroscience, Danube University, Krems, Austria, and Department of Neurology, Landesnervenklinik Klosterneuburg- Gugging, Austria, b Department of Neurology, University of Vienna, Austria
Correspondence to: Dr Andreas Seiser, Department of Neurology, Landesnervenklinik Gugging, Hauptstra

45. Central Pontine Myelinolysis After Alcohol Withdrawal
Here you can find the article written by Ziona Haklai, MSc, Shimon Glick, MD andJochanan Benbassat, MD, which was published in IMAJ. IMAJ 2000; 2; May;
http://www.ima.org.il/imaj/aug02-21.htm
Past Issues August 2002, Table of Contents >> Central Pontine Home Page Instruction for authors Search Facilities Subscribing to IMAJ ... Contact Us Central Pontine Myelinolysis after Alcohol Withdrawal
C
lick here for article written by Isabelle Korn-Lubetzki, MD, Yelena Virozub, MD and Hedi Orbach, MD.
IMAJ 2002; 7; August; 656
ddddddddddddddddddddddddddddddddddddddd Abst Full Text

46. Arch Neurol -- Ring-Enhancing Lesion In Central Pontine Myelinolysis, June 2005,
RingEnhancing Lesion in central pontine myelinolysis. Arch Neurol. A, TheT1-weighted axial plane MRI shows subtle left pontine swelling (arrow).
http://archneur.ama-assn.org/cgi/content/extract/62/6/1016
Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress
Vol. 62 No. 6, June 2005 Featured Link E-mail Alerts Images in Neurology Article Options Full text PDF Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Choksi R Roach ES Contact me when this article is cited
Ring-Enhancing Lesion in Central Pontine Myelinolysis Arch Neurol. Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. A 4-year-old boy was seen in an emergency department after 3 days of vomiting and watery diarrhea. After his sodium level decreased from 136 to 118 mEq/L, he had a seizure, resulting in respiratory arrest, and required mechanical ventilation. His sodium level increased to 128 mEq/L with rehydration, but

47. Magnetic Resonance Imaging Detection Of A Lesion Compatible With Central Pontine
Detection of a Lesion Compatible With central pontine myelinolysis in a MRI brain scan revealed typical findings of central pontine myelinolysis,
http://jon.sagepub.com/cgi/content/abstract/11/4/441

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Journal of Neuroimaging, Vol. 11, No. 4, 441-443 (2001)
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Magnetic Resonance Imaging Detection of a Lesion Compatible With Central Pontine Myelinolysis in a Pregnant Patient With Recurrent Vomiting and Confusion
Beth Valiulis Louisiana State University Health Sciences Center Roger E. Kelley Louisiana State University Health Sciences Center Mardjohan Hardjasudarma Louisiana State University Health Sciences Center Steven London Louisiana State University Health Sciences Center The authors report a patient who presented with unexplained confusion. She was 15 weeks pregnant and had been having recurrent

48. The Journal Of Trauma: Injury, Infection, And Critical Care - UserLogin
central pontine myelinolysis and/or extrapontine myelinolysis are rare The absence of central pontine myelinolysis in our case is in accordance with the
http://www.jtrauma.com/pt/re/jtrauma/fulltext.00005373-199803000-00030.htm
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49. Central Pontine Myelinolysis In Chronic Renal Failure : A Case Report.
Indian Journal of Nephrology. 1992 JanMar; 2(1) 19-20.
http://medind.nic.in/imvw/imvw17595.html
Extracted from IndMED Bhowmik DM; Dandi BG; Kale SA; Wadia NH; Bulchand S Laslok Hospital and Research Centre, 15, Dr. G Deshmukh Marg, Bombay 400026 Central pontine myelinolysis in chronic renal failure : a case report. Indian Journal of Nephrology. 1992 Jan-Mar; 2(1): 19-20 ABSTRACT: We report a patient with renal failure, altered sensorium, bilateral cerebellar ataxia and pathological laughter. MRI showed demyelination of the pons and midbrain. He showed a complete recovery from the neurological deficit and successful renal transplantation was later carried out. KEYWORDS: Myelinolysis, Central Pontine/ET; Myelinolysis, Central Pontine/PA; Kidney Failure, Chronic/CO; Case REport; Human; Male; Adolescence References: 5 Record Identifier: NI002453

50. Journal Of Computer Assisted Tomography - UserLogin
Reversal of MR Findings of central pontine myelinolysis (1) first describedcentral pontine myelinolysis (CPM) in 1959 as a disease occurring in
http://www.jcat.org/pt/re/jcat/fulltext.00004728-199811000-00027.htm
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51. Medical Image Database, Radiology Teaching Files And Cases, MedPix™: Single
central pontine myelinolysis, CPM Factoid 237 Created 1988-01-01 000000-05 With the advent of CT and MR, central pontine myelinolysis (CPM) is
http://rad.usuhs.mil/medpix/radpix.html?mode=single&comebackto=mode=geo_browse&r

52. Medical Image Database, Radiology Teaching Files And Cases, MedPix™: Factoid Im
TOPIC central pontine myelinolysis (CPM) (osmotic myelinolysis) Magnify Centralpontine myelinolysis (CPM) ( central pontine myelinolysis (CPM) ( .
http://rad.usuhs.mil/synapse/radpix.html?mode=factoid_images&recnum=1501

53. MEDArticleMgr
central pontine myelinolysis is a condition characterized by nerve damage There is no known cure for central pontine myelinolysis and treatment is
http://www.drgreene.org/body.cfm?id=49&action=display&articlenum=775

54. JPMA :::
Extra pontine myelinolysis of the basal ganglia without central pontine central pontine myelinolysis temporally related to hypophosphatemia.
http://jpma.org.pk/jpma/6june05/fulltex11.htm
Case Report
Extra Pontine Myelinolysis associated with Hypophosphatemia
Faisal Qadir, Asim Hasan, Moeen Masood*
Departments of Medicine and Neurology, Liaquat National Hospital, Karachi and Regions Hospital, University of Minnesota*, St. Paul, Minneapolis, USA.
Introduction Focal symmetric demyelination in the CNS may be precipitated by aggressive correction of a hyper or hypoosmolar state - osmotic myelinolysis.1 Since the first descriptions of central pontine myelinolysis (CPM) were put forth in 1959 in alcoholic patients, it has become evident that myelinolysis is not exclusively restricted to the pons. In many cases myelinolysis may share other brain regions, while in still others the pons may not be affected at all - extra-pontine myelinolysis(EPM).2 Hence, specific anatomical locations are more susceptible to demyelination than others.
We have reviewed the published cases of extra pontine myelinolysis and believe this to be the first report of EPM occurring in the setting of severe hypophosphatemia.

55. Central Pontine Myelinolysis: Clinical And EEG Considerations
central pontine myelinolysis Clinical and EEG Considerations. AnnaMaria Lawson, R.EEG T.,a and Ernst Niedermeyer, MDb
http://apt.allenpress.com/aptonline/?request=get-abstract&issn=1086-508X&volume=

56. Parkinsonism And Recovery In Central And Extrapontine Myelinolysis Panagariya As
central pontine myelinolysis is a demyelinating affection of central pons diagnosed We report a case of central pontine and extra pontine myelinolysis,
http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2005;volume=53;iss

57. Central Pontine Myelinolysis And Pregnancy -- Castillo Et Al. 73 (3): 459 -- Obs
central pontine myelinolysis and pregnancy. RA Castillo, RA Ray, and F Yaghmai.central pontine myelinolysis, also known as osmotic demyelination syndrome,
http://www.greenjournal.org/cgi/content/abstract/73/3/459
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Articles
Central pontine myelinolysis and pregnancy
RA Castillo, RA Ray, and F Yaghmai Central pontine myelinolysis, also known as osmotic demyelination syndrome, is an uncommon disorder associated with rapid correction of severe hyponatremia. We present the case of a healthy young pregnant woman with hyperemesis gravidarum who developed severe hyponatremia (serum sodium 103 mEq/L). After rapid correction of her serum sodium within 12-15 hours with a 0.9% saline solution, the patient became comatose and died of sepsis and respiratory failure. Examination of the brain showed extensive demyelination in both pontine and extrapontine areas.
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58. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Neurological_Disor
EMedicine - central pontine myelinolysis An introduction, Drkoop MedicalEncyclopedia central pontine myelinolysis - A definition of central pontine
http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Neurologica
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59. Central Pontine Myelinolysis
Return to Index.
http://www.nemcrad.org/neuro/Diseases/CentralPontineMyelinolysis.html

60. Help HER - » Understanding Hyperemesis | Complications | Neurological Condition
eMedicine.com central pontine myelinolysis External Link MEDLINEplus MedicalEncyclopedia central pontine myelinolysis External Link
http://www.hyperemesis.org/hyperemesis-gravidarum/complications/neurological.php
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19-24 months Over 25 months Home Understanding Hyperemesis Complications Related Links: Parenteral (Intravenous) Nutritional Therapy Offsite Resources: PubMed Research Find more abstracts about Wernicke's Encephalopathy and HG than the many we have listed at the bottom of this page.
Neurological Conditions
Neurological Conditions like Wernicke's Encephalopathy and Central Pontine Myelinolysis are easily treated, but most likely to cause a fatal result for the mother and unborn child if left untreated. Considering the vast amount of research, it is amazing that many health care professionals are still unaware of these complications. Wernicke's Encephalopathy Classic Signs: Diplopia, nystagmus, disorientation, confusion, and coma. Unfortunately, Wenicke's Encephalopathy (WE) is not uncommon in hyperemesis gravidarum due to malnutrition, yet is very often goes unrecognized until significant and potentially permanent morbidity occurs. It can be fatal in up to 20% of cases, and may even cause spontaneous abortion (miscarriage).

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